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yes yes no 313 0 PCNIEH+AdvOT7d6df7ab.I+20 Type 1C WinAnsi yes yes no 314 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-06-13 02:41:15 CEST RepresentationInformation: pmc_9133327.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-05-31 06:21:34 CEST Size: 1311517 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 543 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: An Imidazoline 2 Receptor Ligand Relaxes Mouse Aorta via Off-Target Mechanisms Resistant to Aging Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Item: Title: Materials and Methods Destination: flink2 Children: Item: Title: Animals Destination: slink1 Item: Title: Preparation of Isolated Aortic Rings Destination: slink2 Item: Title: Evaluation of Aortic Reactivity Destination: slink3 Item: Title: Measurement of Prostanoid Production Destination: slink4 Item: Title: Statistical Analysis Destination: slink5 Item: Title: Chemicals Destination: slink6 Item: Title: Results Destination: flink3 Children: Item: Title: MCR5 Induces Greater Relaxations Than B06 and 2-BFI Destination: slink7 Item: Title: MCR5 Relaxations Are Largely Non-mediated by I2R Destination: slink8 Item: Title: MCR5 Relaxations Are Higher in KCl Pre-Contracted Vessels Destination: slink9 Item: Title: MCR5 Blocks Smooth Muscle L-Type Voltage-Gated Ca2+ Channels Destination: slink10 Item: Title: MCR5 Relaxations Are Modulated by KATP, Voltage-Gated K+ Channels, and the Na+/K+-ATPase Destination: slink11 Item: Title: MCR5 Relaxations Are Modulated by Endothelial-Derived NO and Prostacyclin Destination: slink12 Item: Title: MCR5 Relaxations Are Not Impaired in Old Mice Despite the Presence of Endothelial Dysfunction Destination: slink13 Item: Title: Discussion Destination: flink4 Item: Title: Data Availability 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