1b8ee49c11436788eca9a2641831af36 pmc_9143151.pdf 72a650881e18f594348787f1c18ecd73769db06a pmc_9143151.pdf b282110ce826ccddd8cba7e4a69aceab042ffc1fb5ae5f4c19da75e60e2b4340 pmc_9143151.pdf Title: Bartonella Endocarditis in Spain: Case Reports of 21 Cases Subject: Blood culture negative endocarditis (BCNE) is frequent in infective endocarditis (IE). One of the causes of BCNE is fastidious microorganisms, such as Bartonella spp. The aim of this study was to describe the epidemiologic, clinical characteristics, management and outcomes of patients with Bartonella IE from the “Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES)”cohort. Here we presented 21 cases of Bartonella IE. This represents 0.3% of a total of 5590 cases and 2% of the BCNE from the GAMES cohort. 62% were due to Bartonella henselae and 38% to Bartonella quintana. Cardiac failure was the main presenting form (61.5% in B. hensalae, 87.5% in B. quintana IE) and the aortic valve was affected in 85% of the cases (76% in B. henselae, 100% in B. quintana IE). Typical signs such as fever were recorded in less than 40% of patients. Echocardiography showed vegetations in 92% and 100% of the patients with B. henselae and B. quintana, respectively. Culture was positive only in one patient and the remaining were diagnosed by serology and PCR. PCR was the most useful tool allowing for diagnosis in 16 patients (100% of the studied valves). Serology, at titers recommended by guidelines, only coincided with PCR in 52.4%. Antimicrobial therapy, in different combinations, was used in all cases. Surgery was performed in 76% of the patients. No in-hospital mortality was observed. One-year mortality was 9.4%. This article remarks the importance for investigating the presence of Bartonella infection as causative agent in all BCNE since the diagnosis needs specific microbiological tools and patients could benefit of a specific treatment. Keywords: infective endocarditis; blood culture negative endocarditis; Bartonella endocarditis;Bartonella spp. Author: Lara García-Álvarez, Concepción García-García, Patricia Muñoz, María del Carmen Fariñas-Álvarez, Manuel Gutiérrez Cuadra, Nuria Fernández-Hidalgo, Elisa García-Vázquez, Encarnación Moral-Escudero, María del Mar Alonso-Socas, Dácil García-Rosado, Carmen Hidalgo-Tenorio, Fernando Domínguez, Josune Goikoetxea-Agirre, Juan Carlos Gainzarain, María Ángeles Rodríguez-Esteban, Xerach Bosch-Guerra, José A. Oteo and on behalf of Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES) Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue May 10 12:21:38 2022 CEST ModDate: Tue May 10 12:37:13 2022 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 326771 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LITXOQ+VnURWPalladioL Type 1 Custom yes yes no 10 0 UBXWFN+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 ROTFYG+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 EKWVOJ+URWPalladioL-Ital Type 1 Custom yes yes no 24 0 UVMWEV+URWPalladioL-BoldItal Type 1 Custom yes yes no 28 0 FFAYKL+VnURWPalladioL-Bold Type 1 Custom yes yes no 32 0 UXHOAG+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 51 0 JGMOZW+CMSY10 Type 1 Builtin yes yes no 79 0 WABLSD+SFRM1000 Type 1 Custom yes yes no 101 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-06-26 02:47:13 CEST RepresentationInformation: pmc_9143151.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-05-30 02:39:24 CEST Size: 326771 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 313 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Results Destination: section.2 Children: Item: Title: Epidemiological Data Destination: subsection.2.1 Item: Title: Clinical Features Destination: subsection.2.2 Item: Title: Microbiological Diagnosis Destination: subsection.2.3 Item: Title: Treatment and Outcome Destination: subsection.2.4 Item: Title: Discussion Destination: section.3 Item: Title: Materials and Methods Destination: section.4 Children: Item: Title: Patients’ Recruitment Destination: subsection.4.1 Item: Title: Definitions Destination: subsection.4.2 Item: Title: Statistics Destination: subsection.4.3 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.5 Info: Title: Bartonella Endocarditis in Spain: Case Reports of 21 Cases Author: Lara García-Álvarez, Concepción García-García, Patricia Muñoz, María del Carmen Fariñas-Álvarez, Manuel Gutiérrez Cuadra, Nuria Fernández-Hidalgo, Elisa García-Vázquez, Encarnación Moral-Escudero, María del Mar Alonso-Socas, Dácil García-Rosado, Carmen Hidalgo-Tenorio, Fernando Domínguez, Josune Goikoetxea-Agirre, Juan Carlos Gainzarain, María Ángeles Rodríguez-Esteban, Xerach Bosch-Guerra, José A. Oteo and on behalf of Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES) Subject: Blood culture negative endocarditis (BCNE) is frequent in infective endocarditis (IE). One of the causes of BCNE is fastidious microorganisms, such as Bartonella spp. The aim of this study was to describe the epidemiologic, clinical characteristics, management and outcomes of patients with Bartonella IE from the “Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES)”cohort. Here we presented 21 cases of Bartonella IE. This represents 0.3% of a total of 5590 cases and 2% of the BCNE from the GAMES cohort. 62% were due to Bartonella henselae and 38% to Bartonella quintana. Cardiac failure was the main presenting form (61.5% in B. hensalae, 87.5% in B. quintana IE) and the aortic valve was affected in 85% of the cases (76% in B. henselae, 100% in B. quintana IE). Typical signs such as fever were recorded in less than 40% of patients. Echocardiography showed vegetations in 92% and 100% of the patients with B. henselae and B. quintana, respectively. Culture was positive only in one patient and the remaining were diagnosed by serology and PCR. PCR was the most useful tool allowing for diagnosis in 16 patients (100% of the studied valves). Serology, at titers recommended by guidelines, only coincided with PCR in 52.4%. Antimicrobial therapy, in different combinations, was used in all cases. Surgery was performed in 76% of the patients. No in-hospital mortality was observed. One-year mortality was 9.4%. This article remarks the importance for investigating the presence of Bartonella infection as causative agent in all BCNE since the diagnosis needs specific microbiological tools and patients could benefit of a specific treatment. Keywords: infective endocarditis; blood culture negative endocarditis; Bartonella endocarditis;Bartonella spp. Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue May 10 12:21:38 CEST 2022 ModDate: Tue May 10 12:37:13 CEST 2022 ID: 0xc50e712078a049527013e337084520b9, 0xc50e712078a049527013e337084520b9 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: FFAYKL+VnURWPalladioL-Bold FontSubset: true FirstChar: 129 LastChar: 226 FontDescriptor: FontName: FFAYKL+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: ROTFYG+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 241 FontDescriptor: FontName: ROTFYG+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WABLSD+SFRM1000 FontSubset: true FirstChar: 180 LastChar: 180 FontDescriptor: FontName: WABLSD+SFRM1000 Flags: Symbolic FontBBox: -189, -321, 1456, 937 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: EKWVOJ+URWPalladioL-Ital FontSubset: true FirstChar: 2 LastChar: 122 FontDescriptor: FontName: EKWVOJ+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: LITXOQ+VnURWPalladioL FontSubset: true FirstChar: 129 LastChar: 243 FontDescriptor: FontName: LITXOQ+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: UVMWEV+URWPalladioL-BoldItal FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: UVMWEV+URWPalladioL-BoldItal Flags: Symbolic FontBBox: -170, -300, 1073, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: UBXWFN+URWPalladioL-Bold FontSubset: true FirstChar: 3 LastChar: 241 FontDescriptor: FontName: UBXWFN+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JGMOZW+CMSY10 FontSubset: true FirstChar: 6 LastChar: 21 FontDescriptor: FontName: JGMOZW+CMSY10 Flags: Symbolic FontBBox: -29, -960, 1116, 775 FontFile: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 34, 323, 152, 332 Annotation: Subtype: Link Rect: 34, 311, 96, 320 Annotation: Subtype: Link Rect: 34, 164, 96, 186 Annotation: Subtype: Link Rect: 126, 90, 154, 99 Annotation: Subtype: Link Rect: 34, 78, 147, 87 Annotation: Subtype: Link Rect: 34, 756, 167, 792 Annotation: Subtype: Link Rect: 515, 756, 560, 792 Annotation: Subtype: Link Rect: 132, 679, 143, 693 Annotation: Subtype: Link Rect: 318, 666, 329, 680 Annotation: Subtype: Link Rect: 159, 641, 170, 655 Annotation: Subtype: Link Rect: 387, 629, 398, 643 Annotation: Subtype: Link Rect: 117, 17, 279, 28 Annotation: Subtype: Link Rect: 400, 17, 560, 28 Annotation: Subtype: Link Rect: 34, 444, 87, 463 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 479, 555, 486, 564 ActionDest: 110 Annotation: Subtype: Link Rect: 208, 529, 215, 538 ActionDest: 110 Annotation: Subtype: Link Rect: 216, 529, 223, 538 ActionDest: 110 Annotation: Subtype: Link Rect: 541, 517, 548, 526 ActionDest: 110 Annotation: Subtype: Link Rect: 549, 517, 556, 526 ActionDest: 110 Annotation: Subtype: Link Rect: 279, 467, 286, 476 ActionDest: 110 Annotation: Subtype: Link Rect: 437, 441, 444, 451 ActionDest: 110 Annotation: Subtype: Link Rect: 444, 442, 451, 451 ActionDest: 110 Annotation: Subtype: Link Rect: 292, 379, 299, 388 ActionDest: 110 Annotation: Subtype: Link Rect: 520, 366, 527, 375 ActionDest: 110 Annotation: Subtype: Link Rect: 358, 341, 365, 350 ActionDest: 110 Annotation: Subtype: Link Rect: 366, 341, 373, 350 ActionDest: 110 Annotation: Subtype: Link Rect: 255, 316, 267, 325 ActionDest: 110 Annotation: Subtype: Link Rect: 381, 266, 393, 275 ActionDest: 110 Annotation: Subtype: Link Rect: 393, 266, 405, 275 ActionDest: 110 Annotation: Subtype: Link Rect: 417, 241, 429, 250 ActionDest: 110 Annotation: Subtype: Link Rect: 205, 216, 217, 225 ActionDest: 110 Annotation: Subtype: Link Rect: 218, 190, 230, 199 ActionDest: 110 Annotation: Subtype: Link Rect: 230, 190, 242, 199 ActionDest: 110 Annotation: Subtype: Link Rect: 245, 191, 257, 199 ActionDest: 110 Annotation: Subtype: Link Rect: 361, 90, 373, 99 ActionDest: 110 Annotation: Subtype: Link Rect: 374, 90, 386, 99 ActionDest: 110 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 394, 723, 406, 732 ActionDest: 110 Annotation: Subtype: Link Rect: 408, 723, 420, 732 ActionDest: 110 Annotation: Subtype: Link Rect: 399, 647, 411, 657 ActionDest: 110 Annotation: Subtype: Link Rect: 411, 648, 423, 657 ActionDest: 113 Annotation: Subtype: Link Rect: 426, 647, 438, 657 ActionDest: 113 Annotation: Subtype: Link Rect: 526, 245, 532, 254 ActionDest: 76 Annotation: Subtype: Link Rect: 552, 245, 559, 254 ActionDest: 86 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 202, 349, 209, 358 ActionDest: 86 Page: Sequence: 5 Page: Sequence: 6 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 423, 420, 430, 432 ActionDest: 86 Annotation: Subtype: Link Rect: 214, 319, 221, 331 ActionDest: 92 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 284, 522, 296, 531 ActionDest: 113 Annotation: Subtype: Link Rect: 552, 519, 559, 531 ActionDest: 92 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 235, 586, 247, 596 ActionDest: 113 Annotation: Subtype: Link Rect: 223, 524, 235, 533 ActionDest: 113 Annotation: Subtype: Link Rect: 238, 524, 250, 533 ActionDest: 113 Annotation: Subtype: Link Rect: 360, 511, 372, 520 ActionDest: 113 Annotation: Subtype: Link Rect: 375, 511, 387, 520 ActionDest: 113 Annotation: Subtype: Link Rect: 180, 499, 192, 508 ActionDest: 113 Annotation: Subtype: Link Rect: 329, 486, 341, 495 ActionDest: 113 Annotation: Subtype: Link Rect: 341, 486, 353, 495 ActionDest: 116 Annotation: Subtype: Link Rect: 447, 461, 454, 470 ActionDest: 110 Annotation: Subtype: Link Rect: 454, 461, 466, 470 ActionDest: 113 Annotation: Subtype: Link Rect: 446, 273, 458, 282 ActionDest: 110 Annotation: Subtype: Link Rect: 215, 210, 227, 219 ActionDest: 110 Annotation: Subtype: Link Rect: 227, 210, 239, 219 ActionDest: 110 Annotation: Subtype: Link Rect: 240, 210, 252, 219 ActionDest: 113 Annotation: Subtype: Link Rect: 252, 210, 264, 219 ActionDest: 113 Annotation: Subtype: Link Rect: 264, 210, 276, 219 ActionDest: 113 Annotation: Subtype: Link Rect: 277, 210, 289, 219 ActionDest: 113 Annotation: Subtype: Link Rect: 289, 210, 301, 219 ActionDest: 113 Annotation: Subtype: Link Rect: 304, 210, 316, 219 ActionDest: 116 Annotation: Subtype: Link Rect: 473, 172, 485, 181 ActionDest: 113 Annotation: Subtype: Link Rect: 422, 135, 434, 144 ActionDest: 113 Annotation: Subtype: Link Rect: 434, 135, 446, 144 ActionDest: 116 Annotation: Subtype: Link Rect: 380, 97, 392, 106 ActionDest: 116 Annotation: Subtype: Link Rect: 476, 72, 488, 81 ActionDest: 110 Annotation: Subtype: Link Rect: 488, 72, 500, 81 ActionDest: 113 Annotation: Subtype: Link Rect: 501, 72, 513, 81 ActionDest: 116 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 402, 637, 409, 646 ActionDest: 110 Annotation: Subtype: Link Rect: 410, 637, 417, 646 ActionDest: 110 Annotation: Subtype: Link Rect: 375, 624, 387, 633 ActionDest: 110 Annotation: Subtype: Link Rect: 418, 549, 430, 558 ActionDest: 116 Annotation: Subtype: Link Rect: 315, 511, 327, 521 ActionDest: 113 Annotation: Subtype: Link Rect: 327, 511, 339, 521 ActionDest: 116 Annotation: Subtype: Link Rect: 255, 486, 267, 495 ActionDest: 113 Annotation: Subtype: Link Rect: 267, 486, 279, 495 ActionDest: 116 Annotation: Subtype: Link Rect: 399, 486, 411, 495 ActionDest: 110 Annotation: Subtype: Link Rect: 360, 436, 372, 445 ActionDest: 116 Annotation: Subtype: Link Rect: 337, 411, 349, 420 ActionDest: 116 Annotation: Subtype: Link Rect: 377, 348, 389, 357 ActionDest: 116 Annotation: Subtype: Link Rect: 466, 260, 473, 269 ActionDest: 110 Annotation: Subtype: Link Rect: 473, 261, 485, 269 ActionDest: 113 Annotation: Subtype: Link Rect: 486, 260, 498, 269 ActionDest: 113 Annotation: Subtype: Link Rect: 498, 260, 510, 269 ActionDest: 116 Annotation: Subtype: Link Rect: 513, 260, 525, 269 ActionDest: 116 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 481, 637, 488, 646 ActionDest: 110 Annotation: Subtype: Link Rect: 231, 586, 243, 596 ActionDest: 116 Annotation: Subtype: Link Rect: 388, 536, 400, 545 ActionDest: 116 Annotation: Subtype: Link Rect: 400, 536, 412, 545 ActionDest: 116 Annotation: Subtype: Link Rect: 392, 322, 399, 331 ActionDest: 110 Annotation: Subtype: Link Rect: 400, 322, 412, 331 ActionDest: 110 Annotation: Subtype: Link Rect: 536, 283, 560, 294 Annotation: Subtype: Link Rect: 165, 271, 403, 282 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 464, 667, 501, 678 Annotation: Subtype: Link Rect: 508, 667, 544, 678 Annotation: Subtype: Link Rect: 158, 633, 195, 643 Annotation: Subtype: Link Rect: 201, 633, 237, 643 Annotation: Subtype: Link Rect: 347, 622, 384, 632 Annotation: Subtype: Link Rect: 131, 599, 168, 609 Annotation: Subtype: Link Rect: 283, 563, 320, 574 Annotation: Subtype: Link Rect: 158, 530, 195, 540 Annotation: Subtype: Link Rect: 436, 494, 474, 505 Annotation: Subtype: Link Rect: 153, 438, 191, 448 Annotation: Subtype: Link Rect: 274, 402, 311, 413 Annotation: Subtype: Link Rect: 223, 391, 391, 402 Annotation: Subtype: Link Rect: 463, 368, 500, 379 Annotation: Subtype: Link Rect: 398, 299, 436, 310 Annotation: Subtype: Link Rect: 494, 287, 531, 298 Annotation: Subtype: Link Rect: 520, 276, 557, 287 Annotation: Subtype: Link Rect: 222, 253, 259, 264 Annotation: Subtype: Link Rect: 251, 230, 288, 241 Annotation: Subtype: Link Rect: 190, 207, 227, 218 Annotation: Subtype: Link Rect: 321, 196, 358, 206 Annotation: Subtype: Link Rect: 86, 172, 298, 183 Annotation: Subtype: Link Rect: 456, 149, 494, 160 Annotation: Subtype: Link Rect: 394, 126, 431, 137 Annotation: Subtype: Link Rect: 472, 103, 509, 114 Annotation: Subtype: Link Rect: 516, 103, 552, 114 Annotation: Subtype: Link Rect: 443, 80, 481, 91 Annotation: Subtype: Link Rect: 487, 80, 523, 91 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 109, 713, 146, 723 Annotation: Subtype: Link Rect: 310, 690, 347, 700 Annotation: Subtype: Link Rect: 520, 666, 557, 677 Annotation: Subtype: Link Rect: 59, 655, 95, 665 Annotation: Subtype: Link Rect: 199, 632, 237, 642 Annotation: Subtype: Link Rect: 243, 632, 279, 642 Annotation: Subtype: Link Rect: 467, 608, 505, 619 Annotation: Subtype: Link Rect: 511, 608, 547, 619 Annotation: Subtype: Link Rect: 346, 586, 384, 596 Annotation: Subtype: Link Rect: 402, 562, 439, 573 Annotation: Subtype: Link Rect: 259, 539, 296, 550 Annotation: Subtype: Link Rect: 277, 482, 560, 493 Annotation: Subtype: Link Rect: 56, 470, 95, 481 Annotation: Subtype: Link Rect: 152, 448, 190, 458 Annotation: Subtype: Link Rect: 104, 425, 141, 435 Annotation: Subtype: Link Rect: 337, 401, 375, 412 Annotation: Subtype: Link Rect: 256, 378, 294, 389 Annotation: Subtype: Link Rect: 242, 356, 279, 366 Annotation: Subtype: Link Rect: 361, 332, 399, 343 Annotation: Subtype: Link Rect: 191, 310, 228, 320 Annotation: Subtype: Link Rect: 262, 287, 300, 297 Annotation: Subtype: Link Rect: 394, 240, 432, 251 Annotation: Subtype: Link Rect: 438, 240, 474, 251 Annotation: Subtype: Link Rect: 410, 217, 448, 228 Annotation: Subtype: Link Rect: 454, 217, 490, 228 Annotation: Subtype: Link Rect: 131, 195, 168, 205 Annotation: Subtype: Link Rect: 175, 195, 211, 205 Annotation: Subtype: Link Rect: 149, 161, 186, 171 Annotation: Subtype: Link Rect: 95, 138, 132, 148 Annotation: Subtype: Link Rect: 59, 115, 96, 125 Annotation: Subtype: Link Rect: 415, 91, 452, 102 Annotation: Subtype: Link Rect: 95, 69, 133, 79 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 108, 724, 146, 735 Annotation: Subtype: Link Rect: 151, 690, 189, 700 Annotation: Subtype: Link Rect: 519, 666, 557, 677 Annotation: Subtype: Link Rect: 167, 632, 204, 642 Annotation: Subtype: Link Rect: 500, 620, 537, 631 Annotation: Subtype: Link Rect: 520, 586, 557, 596 Annotation: Subtype: Link Rect: 203, 563, 240, 573 Annotation: Subtype: Link Rect: 251, 539, 289, 550 Annotation: Subtype: Link Rect: 495, 516, 532, 527 Annotation: Subtype: Link Rect: 59, 494, 96, 504 Annotation: Subtype: Link Rect: 59, 460, 96, 470 Annotation: Subtype: Link Rect: 393, 436, 431, 447 Annotation: Subtype: Link Rect: 411, 414, 449, 424 Annotation: Subtype: Link Rect: 127, 391, 164, 401 Annotation: Subtype: Link Rect: 520, 378, 557, 389 Annotation: Subtype: Link Rect: 395, 355, 432, 366 Annotation: Subtype: Link Rect: 273, 332, 310, 343 Annotation: Subtype: Link Rect: 113, 310, 150, 320 Checksum: d0f19412 Type: CRC32 Checksum: 1b8ee49c11436788eca9a2641831af36 Type: MD5 Checksum: 72a650881e18f594348787f1c18ecd73769db06a Type: SHA-1 Checksum: b282110ce826ccddd8cba7e4a69aceab042ffc1fb5ae5f4c19da75e60e2b4340 Type: SHA-256