c82714e3f3d3d8a80339a25f65fc05a5 pmc_9143348.pdf be2cb9637d038964672d881a5c86c94cf3c34a3d pmc_9143348.pdf c2facebf8645f55e21b7c163b8f351372576516b7d5d72f7d2b5c6f8d4277713 pmc_9143348.pdf Title: Usefulness of Muscle Ultrasound to Study Sarcopenic Obesity: A Pilot Case-Control Study Subject: Background and objectives: Sarcopenic obesity (SO) is an emerging problem, especially in candidates for bariatric surgery (BS). We hypothesized that musculoskeletal ultrasound (MUS), a simple and accessible method, could be a reliable index of SO. Materials and Methods: A cross-sectional pilot study including 122 subjects (90 cases and 32 controls, 73% female, mean age: 51.2 years) who underwent BS was conducted at University Hospital Mútua Terrassa. The lean mass (LM) was calculated by bioelectrical impedance analysis (BIA) and the thigh muscle thickness (TMT) by MUS. To identify the subjects with SO by BIA, we used skeletal muscle index (SMI). The validity of MUS was determined using the ROC curve. Results: The mean BMI in the obesity group was 44.22 kg/m2. We observed a correlation between the LM and SMI assessed by BIA and the TMT assessed by MUS (R = 0.46, p < 0.001). This correlation was maintained at significant levels in the SO group (n = 40): R = 0.79; p = 0.003). The TMT assessed by MUS was able to predict SMI using BIA (AUC 0.77; 95% CI: 0.68242 to 0.84281). The optimal cut-off point for maximum efficiency was 1.57 cm in TMT (sensitivity = 75.6% and specificity = 71.1%). Conclusions: The TMT of the quadriceps assessed by US is a useful tool for identifying subjects with SO. Larger studies to validate this simple low-cost screening strategy are warranted. Keywords: sarcopenic obesity; fat mass; lean mass; ultrasound Author: Andreu Simó-Servat, Montse Ibarra, Mireia Libran, Silvia Rodríguez, Verónica Perea, Carmen Quirós, Aida Orois, Noelia Pérez, Rafael Simó and Maria-José Barahona Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri May 20 06:09:12 2022 CEST ModDate: Fri May 20 08:16:45 2022 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1048184 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- YFNERV+VnURWPalladioL Type 1 Custom yes yes no 10 0 EHKAKE+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 VXAYWP+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 LRHHYY+URWPalladioL-Ital Type 1 Custom yes yes no 24 0 XWOCXD+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 46 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 49 0 QMDDXF+CMSY10 Type 1 Builtin yes yes no 71 0 SPXLNH+PazoMath Type 1 Builtin yes yes no 75 0 YFQMYX+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 88 0 WSNVWB+PalatinoLinotype-Italic TrueType WinAnsi yes yes yes 96 0 RCIBEL+PalatinoLinotype-Bold TrueType WinAnsi yes yes yes 100 0 ICOUID+PalatinoLinotype-Roman TrueType WinAnsi yes yes yes 104 0 BKYZOR+ArialMT TrueType WinAnsi yes yes yes 108 0 ODVTOW+URWPalladioL-BoldItal Type 1 Custom yes yes no 117 0 WSNVWB+PalatinoLinotype-Italic TrueType WinAnsi yes yes yes 126 0 RCIBEL+PalatinoLinotype-Bold TrueType WinAnsi yes yes yes 130 0 ICOUID+PalatinoLinotype-Roman TrueType WinAnsi yes yes yes 134 0 YQNCYX+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 138 0 HBYEUF+PalatinoLinotype-BoldItalic TrueType WinAnsi yes yes yes 142 0 BKYZOR+ArialMT TrueType WinAnsi yes yes yes 146 0 WSNVWB+PalatinoLinotype-Italic TrueType WinAnsi yes yes yes 155 0 RCIBEL+PalatinoLinotype-Bold TrueType WinAnsi yes yes yes 159 0 ICOUID+PalatinoLinotype-Roman TrueType WinAnsi yes yes yes 163 0 BKYZOR+ArialMT TrueType WinAnsi yes yes yes 167 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-05-18 03:24:57 CEST RepresentationInformation: pmc_9143348.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-05-18 02:37:06 CEST Size: 1048184 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 325 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: BIA Destination: subsection.2.1 Item: Title: Ultrasonic Technique Destination: subsection.2.2 Item: Title: Statistical Analysis Destination: subsection.2.3 Item: Title: Results Destination: section.3 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.5 Info: Title: Usefulness of Muscle Ultrasound to Study Sarcopenic Obesity: A Pilot Case-Control Study Author: Andreu Simó-Servat, Montse Ibarra, Mireia Libran, Silvia Rodríguez, Verónica Perea, Carmen Quirós, Aida Orois, Noelia Pérez, Rafael Simó and Maria-José Barahona Subject: Background and objectives: Sarcopenic obesity (SO) is an emerging problem, especially in candidates for bariatric surgery (BS). We hypothesized that musculoskeletal ultrasound (MUS), a simple and accessible method, could be a reliable index of SO. Materials and Methods: A cross-sectional pilot study including 122 subjects (90 cases and 32 controls, 73% female, mean age: 51.2 years) who underwent BS was conducted at University Hospital Mútua Terrassa. The lean mass (LM) was calculated by bioelectrical impedance analysis (BIA) and the thigh muscle thickness (TMT) by MUS. To identify the subjects with SO by BIA, we used skeletal muscle index (SMI). The validity of MUS was determined using the ROC curve. Results: The mean BMI in the obesity group was 44.22 kg/m2. We observed a correlation between the LM and SMI assessed by BIA and the TMT assessed by MUS (R = 0.46, p < 0.001). This correlation was maintained at significant levels in the SO group (n = 40): R = 0.79; p = 0.003). The TMT assessed by MUS was able to predict SMI using BIA (AUC 0.77; 95% CI: 0.68242 to 0.84281). The optimal cut-off point for maximum efficiency was 1.57 cm in TMT (sensitivity = 75.6% and specificity = 71.1%). Conclusions: The TMT of the quadriceps assessed by US is a useful tool for identifying subjects with SO. Larger studies to validate this simple low-cost screening strategy are warranted. 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