5974f3a923e56f97756c6d925c8cd184 pmc_9147348.pdf 8ca2efb469c77c966c4300a96531596cfdb1c0a5 pmc_9147348.pdf 061d069afb5d843a198e332822922e4e11de3ce4f7403e376eb8883130ea663b pmc_9147348.pdf Title: Vaccination of Immunocompromised Cats Subject: Immunocompromise is a common condition in cats, especially due to widespread infections with immunosuppressive viruses, such as feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), but also due to chronic non-infectious diseases, such as tumours, diabetes mellitus, and chronic kidney disease, as well as treatment with immunosuppressive drugs, such as glucocorticoids, cyclosporins, or tumour chemotherapy. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from eleven European countries, discusses the current knowledge and rationale for vaccination of immunocompromised cats. So far, there are few data available on vaccination of immunocompromised cats, and sometimes studies produce controversial results. Thus, this guideline summarizes the available scientific studies and fills in the gaps with expert opinion, where scientific studies are missing. Ultimately, this review aims to help veterinarians with their decision-making in how best to vaccinate immunocompromised cats. Keywords: feline; immunocompromise; immunosuppression; immunodeficiency; vaccine; efficacy; safety; duration of immunity; DOI Author: Katrin Hartmann, Karin Möstl, Albert Lloret, Etienne Thiry, Diane D. Addie, Sándor Belák, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Regina Hofmann-Lehmann, Hans Lutz, Fulvio Marsilio, Maria Grazia Pennisi, Séverine Tasker, Uwe Truyen and Margaret J. 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Addie, Sándor Belák, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Regina Hofmann-Lehmann, Hans Lutz, Fulvio Marsilio, Maria Grazia Pennisi, Séverine Tasker, Uwe Truyen and Margaret J. Hosie Subject: Immunocompromise is a common condition in cats, especially due to widespread infections with immunosuppressive viruses, such as feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), but also due to chronic non-infectious diseases, such as tumours, diabetes mellitus, and chronic kidney disease, as well as treatment with immunosuppressive drugs, such as glucocorticoids, cyclosporins, or tumour chemotherapy. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from eleven European countries, discusses the current knowledge and rationale for vaccination of immunocompromised cats. So far, there are few data available on vaccination of immunocompromised cats, and sometimes studies produce controversial results. Thus, this guideline summarizes the available scientific studies and fills in the gaps with expert opinion, where scientific studies are missing. Ultimately, this review aims to help veterinarians with their decision-making in how best to vaccinate immunocompromised cats. Keywords: feline; immunocompromise; immunosuppression; immunodeficiency; vaccine; efficacy; safety; duration of immunity; DOI Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Apr 29 11:24:55 CEST 2022 ModDate: Fri Apr 29 11:26:54 CEST 2022 ID: 0xd77f3a926d355013a51bde03cace2127, 0xd77f3a926d355013a51bde03cace2127 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: RILWGI+EURM10 FontSubset: true FirstChar: 11 LastChar: 34 FontDescriptor: FontName: RILWGI+EURM10 Flags: Symbolic FontBBox: -32, -243, 1060, 720 FontFile: true Font: BaseFont: HJLDNL+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: HJLDNL+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: OUDXPL+URWPalladioL-Ital FontSubset: true FirstChar: 2 LastChar: 151 FontDescriptor: FontName: OUDXPL+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true 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