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Introduction Destination: section1 Item: Title: 2. Materials and Methods Destination: section2 Children: Item: Title: 2.1. Study Design, Setting, and Participants Destination: section3 Item: Title: 2.2. Variables and Measurement Destination: section4 Item: Title: 2.3. Sample Size Calculation Destination: section5 Item: Title: 2.4. Statistical Analysis Destination: section6 Item: Title: 3. Results Destination: section7 Children: Item: Title: 3.1. Participants Destination: section8 Item: Title: 3.2. Main Results Destination: section9 Item: Title: 4. Discussion Destination: section10 Item: Title: 5. Conclusions Destination: section11 Item: Title: Data Availability Destination: section12 Item: Title: Ethical Approval Destination: section13 Item: Title: Consent Destination: section14 Item: Title: Conflicts of Interest Destination: section15 Item: Title: Authors’ Contributions Destination: section16 Info: Title: BMRI_6238099 1..8 Creator: Aspose Ltd. 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