39acb0a8661da30c3a3a468d9a4d8b97 pmc_9257102.pdf 62fe1d407d42c05a554fc5032e70b8b40579f823 pmc_9257102.pdf 90950688e8018fe4496459bb1da2c5c71aac66865162b0de57850df1f1cb188c pmc_9257102.pdf Title: Immunogenicity of Mycobacterial Extracellular Vesicles Isolated From Host-Related Conditions Informs About Tuberculosis Disease Status Subject: Tuberculosis (TB) still represents a major global health problem affecting over 10 million people worldwide. Keywords: Mycobacterium tuberculosis, extracellular vesicles, immunogenicity, diagnostic biomarkers, serology, iron starvation Author: Susanne Gola and Rafael Prados-Rosales Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.18 CreationDate: Thu Jun 16 11:59:50 2022 CEST ModDate: Thu Jun 16 11:59:50 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 3959259 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- PASQMH+MinionPro-Regular Type 1 Custom yes yes no 24 0 JPRIGS+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 25 0 VOCXBV+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 26 0 WAKGUS+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 31 0 UIYKOX+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 32 0 MOCQUH+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 33 0 POAKCH+MinionPro-It Type 1 Custom yes yes no 118 0 YSHGNE+MinionPro-Bold Type 1 Custom yes yes no 178 0 XODHDR+RBLMI Type 1 Builtin yes yes no 180 0 VHMQED+HelveticaNeueLTStd-Md Type 1 Custom yes yes no 272 0 EHEMMI+MTSYN Type 1 Builtin yes yes no 409 0 JYDOCF+MTGU Type 1 Builtin yes yes no 416 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-11 02:29:53 CEST RepresentationInformation: pmc_9257102.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-09-05 13:36:50 CEST Size: 3959259 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 712 FreeObjects: 12 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Immunogenicity of Mycobacterial Extracellular Vesicles Isolated From Host-Related Conditions Informs About Tuberculosis Disease Status Children: Item: Title: Introduction Item: Title: Results Children: Item: Title: Mycobacterium tuberculosis Modifies the Magnitude and Composition of Mycobacterial Extracellular Vesicle Production When Growing Under Iron Starvation Item: Title: Immunogenicity of High Fe and Low Fe Mycobacterial Extracellular Vesicles Children: Item: Title: Immunogenicity of High Fe Mycobacterial Extracellular Vesicles Item: Title: Immunogenicity of Low Fe Mycobacterial Extracellular Vesicles Item: Title: Performance of Disease Biomarkers Item: Title: Discussion Item: Title: Materials and Methods Children: Item: Title: Bacteria and Culture Item: Title: Isolation of Mycobacterial Extracellular Vesicles Item: Title: Nanoparticle Tracking Analysis Item: Title: Label-Free Mass Spectrometry Analysis Item: Title: Serum Samples Item: Title: Immunoblot Item: Title: Image Analysis Item: Title: Statistics (ROC and Accuracy Analyses) Item: Title: Data Availability Statement Item: Title: Ethics Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Supplementary Material Item: Title: References Info: Title: Immunogenicity of Mycobacterial Extracellular Vesicles Isolated From Host-Related Conditions Informs About Tuberculosis Disease Status Author: Susanne Gola and Rafael Prados-Rosales Subject: Tuberculosis (TB) still represents a major global health problem affecting over 10 million people worldwide. Keywords: Mycobacterium tuberculosis, extracellular vesicles, immunogenicity, diagnostic biomarkers, serology, iron starvation Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.18 CreationDate: Thu Jun 16 12:29:50 CEST 2022 ModDate: Thu Jun 16 12:29:50 CEST 2022 ID: 0x03f53162e30ecabb7b2a36bfd66f84fb, 0x03f53162e30ecabb7b2a36bfd66f84fb Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: UIYKOX+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: UIYKOX+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: VHMQED+HelveticaNeueLTStd-Md FontSubset: true FirstChar: 69 LastChar: 121 FontDescriptor: FontName: VHMQED+HelveticaNeueLTStd-Md Flags: Symbolic FontBBox: -165, -221, 1066, 952 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JYDOCF+MTGU FontSubset: true FirstChar: 109 LastChar: 109 FontDescriptor: FontName: JYDOCF+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: MOCQUH+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 243 FontDescriptor: FontName: MOCQUH+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: YSHGNE+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: YSHGNE+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XODHDR+RBLMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: XODHDR+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: POAKCH+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: POAKCH+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: PASQMH+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: PASQMH+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JPRIGS+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 2 LastChar: 124 FontDescriptor: FontName: JPRIGS+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: EHEMMI+MTSYN FontSubset: true FirstChar: 0 LastChar: 24 FontDescriptor: FontName: EHEMMI+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: VOCXBV+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: VOCXBV+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: WAKGUS+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: WAKGUS+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true XMP: Mycobacterium tuberculosis, extracellular vesicles, immunogenicity, diagnostic biomarkers, serology, iron starvation pdfTeX-1.40.18 1.5 application/pdf Immunogenicity of Mycobacterial Extracellular Vesicles Isolated From Host-Related Conditions Informs About Tuberculosis Disease Status Tuberculosis (TB) still represents a major global health problem affecting over 10 million people worldwide. 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