dd5e6895bc3c9e7f6ca1604920a997b3 pmc_9289129.pdf 3cfbd7c24794a719b704bea4401ded89e6b2904c pmc_9289129.pdf 7093565fc05a8b9af4ac72397df43dfa8853ece2da7883b186929f2ed1f426e3 pmc_9289129.pdf Title: Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients Subject: Background: Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. Keywords: atrial fibrillation, stroke, biomarkers, screening, cryptogenic stroke Author: Joan Montaner Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Tue Jun 28 12:54:46 2022 CEST ModDate: Tue Jun 28 12:54:46 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 2396408 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AQYQIT+MinionPro-Regular Type 1 Custom yes yes no 25 0 MPUHDE+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 26 0 AAEZWU+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 27 0 CCVXXJ+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 32 0 XELJTR+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 33 0 LGICPM+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 34 0 XODHDR+RBLMI Type 1 Builtin yes yes no 35 0 GMZCDD+MinionPro-Bold Type 1 Custom yes yes no 84 0 KCJQWO+HelveticaNeueLTStd-Md Type 1 Custom yes yes no 94 0 GEMALB+MinionPro-It Type 1 Custom yes yes no 95 0 TAYJBL+MTSYN Type 1 Builtin yes yes no 125 0 RQMTSU+MTGU Type 1 Builtin yes yes no 132 0 DPEHCO+MinionPro-SemiboldIt Type 1 Custom yes yes no 197 0 NZQTQK+RMTMIB Type 1 Builtin yes yes no 216 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-20 02:30:44 CEST RepresentationInformation: pmc_9289129.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-09-16 02:16:21 CEST Size: 2396408 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 540 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Subjects Children: Item: Title: AFRICAT Study Item: Title: CRYPTO-AF Study Item: Title: Biomarker Quantification Item: Title: Statistical Analysis Item: Title: Results Children: Item: Title: Biomarker Combinations Children: Item: Title: Asymptomatic High-Risk Subjects Children: Item: Title: Comparison to Biomarkers Previously Measured in the Cohort (NT-ProBNP) Item: Title: Cryptogenic Stroke Patients Children: Item: Title: Comparison to Biomarkers Previously Measured in the Cohort (BNP and NT-ProBNP) Item: Title: Discussion Item: Title: Conclusion Item: Title: Data Availability Statement Item: Title: Ethics Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Supplementary Material Item: Title: References Info: Title: Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients Author: Joan Montaner Subject: Background: Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. Keywords: atrial fibrillation, stroke, biomarkers, screening, cryptogenic stroke Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Tue Jun 28 13:24:46 CEST 2022 ModDate: Tue Jun 28 13:24:46 CEST 2022 ID: 0xb31ad677c540e068b1299140ddb86332, 0xb31ad677c540e068b1299140ddb86332 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: CCVXXJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: CCVXXJ+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XELJTR+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: XELJTR+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -165, -214, 1099, 951 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: LGICPM+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 250 FontDescriptor: FontName: LGICPM+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -165, -218, 1125, 947 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XODHDR+RBLMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: XODHDR+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: RQMTSU+MTGU FontSubset: true FirstChar: 36 LastChar: 36 FontDescriptor: FontName: RQMTSU+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: DPEHCO+MinionPro-SemiboldIt FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: DPEHCO+MinionPro-SemiboldIt Flags: Symbolic FontBBox: -216, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GMZCDD+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: GMZCDD+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: NZQTQK+RMTMIB FontSubset: true FirstChar: 60 LastChar: 60 FontDescriptor: FontName: NZQTQK+RMTMIB Flags: Symbolic FontBBox: 0, -250, 994, 706 FontFile: true Font: BaseFont: AQYQIT+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: AQYQIT+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: MPUHDE+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: MPUHDE+HelveticaNeueLTStd-Bd Flags: Symbolic FontBBox: -166, -218, 1078, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: AAEZWU+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 2 LastChar: 224 FontDescriptor: FontName: AAEZWU+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: TAYJBL+MTSYN FontSubset: true FirstChar: 6 LastChar: 21 FontDescriptor: FontName: TAYJBL+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: KCJQWO+HelveticaNeueLTStd-Md FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: KCJQWO+HelveticaNeueLTStd-Md Flags: Symbolic FontBBox: -165, -221, 1066, 952 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GEMALB+MinionPro-It FontSubset: true FirstChar: 40 LastChar: 250 FontDescriptor: FontName: GEMALB+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true XMP: atrial fibrillation, stroke, biomarkers, screening, cryptogenic stroke pdfTeX-1.40.15 1.5 application/pdf Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients Background: Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. 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