af7cd886b99554615ec4b4b2e64b1161 pmc_9325998.pdf 3a7f53bee777e47a87fe2b54cb7ee0cfc5364f26 pmc_9325998.pdf 1490392a3a819798bd1b66b1ed4b0f1f28ca5c49a59b00c62f877f9c46059881 pmc_9325998.pdf Title: Understanding and Predicting Cognitive Improvement of Young Adults in Ischemic Stroke Rehabilitation Therapy Subject: Accurate early predictions of a patient's likely cognitive improvement as a result of a stroke rehabilitation programme can assist clinicians in assembling more effective therapeutic programs. Keywords: cognitive improvement, AI explainability, machine learning (ML), ischemic stroke, predictive models, cognitive therapy, web-based therapy Author: Helard Becerra Martinez Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Thu Jul 7 06:55:46 2022 CEST ModDate: Thu Jul 7 07:47:28 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 22 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 4343597 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KATTGH+HelveticaNeueLTStd-Bd Type 1C WinAnsi yes yes no 51 0 SSSILI+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 56 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 68 0 OJQGIM+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 70 0 EXMHTP+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 75 0 IQUBDH+MinionPro-Regular Type 1C Custom yes yes no 83 0 VKCIIM+MinionPro-Bold Type 1C Custom yes yes no 128 0 KSRXNT+HelveticaNeueLTStd-Md Type 1C Custom yes yes no 130 0 VPAOUG+MinionPro-It Type 1C Custom yes yes no 133 0 GNKBUG+MTSY Type 1C Custom yes yes yes 148 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-28 02:34:24 CEST RepresentationInformation: pmc_9325998.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-09-27 02:17:27 CEST Size: 4343597 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 471 FreeObjects: 27 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Understanding and Predicting Cognitive Improvement of Young Adults in Ischemic Stroke Rehabilitation Therapy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: 1. Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: 2. Related Study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: 3. Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: 3.1. Data Sources Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Children: Item: Title: 3.1.1. Cognitive Records Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: 3.1.2. Therapy Records Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: 3.2. Study Population Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: 3.3. Feature Engineering Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: 3.4. Data Exploration Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: 3.5. Modeling Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Children: Item: Title: 3.5.1. Cognitive Outcome Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: 3.5.2. Pre-processing Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 3.5.3. Classification Algorithms Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: 3.5.4. Performance Evaluation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: 3.5.5. Feature Selection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: 3.5.6. Hyper-Parameters Optimization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: 3.6. Explanation Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 4. Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Children: Item: Title: 4.1. Experiment Data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 4.2. Exploratory Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 4.3. Cognitive Improvement Prediction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: 4.4. Explanation Reports Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Children: Item: Title: 4.4.1. General Interpretation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: 4.4.2. Individual Interpretation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: 5. Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Children: Item: Title: 5.1. On the Data Exploration Process Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: 5.2. On the Modeling Process Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: 5.3. On the Explanatory Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: 5.4. On the Cognitive Improvement Prediction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: 5.5. Limitations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: 5.6. Future Study and Direction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: 6. Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3 Info: Title: Understanding and Predicting Cognitive Improvement of Young Adults in Ischemic Stroke Rehabilitation Therapy Author: Helard Becerra Martinez Subject: Accurate early predictions of a patient's likely cognitive improvement as a result of a stroke rehabilitation programme can assist clinicians in assembling more effective therapeutic programs. 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2022-07-07T11:17:28+05:30 application/pdf Accurate early predictions of a patient's likely cognitive improvement as a result of a stroke rehabilitation programme can assist clinicians in assembling more effective therapeutic programs. 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Annotation: Subtype: Link Rect: 237, 103, 248, 115 Destination: External Annotation: Subtype: Link Rect: 256, 103, 267, 115 Destination: External Annotation: Subtype: Link Rect: 514, 440, 549, 450 Destination: External Annotation: Subtype: Link Rect: 407, 247, 418, 258 Destination: External Annotation: Subtype: Link Rect: 43, 29, 111, 37 Annotation: Subtype: Link Rect: 114, 29, 174, 37 Annotation: Subtype: Link Rect: 433, 29, 551, 38 Page: Label: 20 Sequence: 20 Annotations: Annotation: Subtype: Link Rect: 66, 319, 77, 330 Destination: External Annotation: Subtype: Link Rect: 246, 193, 257, 204 Destination: External Annotation: Subtype: Link Rect: 43, 18, 111, 26 Annotation: Subtype: Link Rect: 114, 18, 174, 26 Annotation: Subtype: Link Rect: 433, 18, 551, 27 Page: Label: 21 Sequence: 21 Annotations: Annotation: Subtype: Link Rect: 70, 650, 171, 659 Annotation: Subtype: Link Rect: 125, 622, 206, 630 Annotation: Subtype: Link Rect: 145, 584, 226, 592 Annotation: Subtype: Link Rect: 70, 555, 151, 564 Annotation: Subtype: Link Rect: 223, 538, 283, 545 Annotation: Subtype: Link Rect: 163, 517, 242, 526 Annotation: Subtype: Link Rect: 104, 434, 178, 441 Annotation: Subtype: Link Rect: 108, 396, 207, 403 Annotation: Subtype: Link Rect: 70, 358, 170, 365 Annotation: Subtype: Link Rect: 104, 329, 193, 337 Annotation: Subtype: Link Rect: 108, 300, 188, 308 Annotation: Subtype: Link Rect: 70, 271, 146, 280 Annotation: Subtype: Link Rect: 70, 197, 161, 204 Annotation: Subtype: Link Rect: 97, 159, 176, 166 Annotation: Subtype: Link Rect: 70, 102, 170, 110 Annotation: Subtype: Link Rect: 331, 687, 461, 697 Annotation: Subtype: Link Rect: 331, 604, 416, 611 Annotation: Subtype: Link Rect: 407, 576, 472, 583 Annotation: Subtype: Link Rect: 431, 555, 512, 564 Annotation: Subtype: Link Rect: 361, 489, 448, 498 Annotation: Subtype: Link Rect: 448, 470, 526, 479 Annotation: Subtype: Link Rect: 411, 452, 518, 460 Annotation: Subtype: Link Rect: 450, 415, 549, 422 Annotation: Subtype: Link Rect: 331, 377, 465, 384 Annotation: Subtype: Link Rect: 368, 347, 451, 356 Annotation: Subtype: Link Rect: 397, 271, 551, 280 Annotation: Subtype: Link Rect: 317, 262, 482, 271 Annotation: Subtype: Link Rect: 365, 195, 461, 204 Annotation: Subtype: Link Rect: 350, 101, 429, 110 Annotation: Subtype: Link Rect: 43, 29, 111, 37 Annotation: Subtype: Link Rect: 114, 29, 174, 37 Annotation: Subtype: Link Rect: 433, 29, 551, 38 Page: Label: 22 Sequence: 22 Annotations: Annotation: Subtype: Link Rect: 148, 642, 223, 649 Annotation: Subtype: Link Rect: 126, 575, 226, 583 Annotation: Subtype: Link Rect: 147, 517, 230, 526 Annotation: Subtype: Link Rect: 191, 498, 291, 508 Annotation: Subtype: Link Rect: 57, 491, 129, 498 Annotation: Subtype: Link Rect: 70, 462, 163, 469 Annotation: Subtype: Link Rect: 70, 432, 154, 441 Annotation: Subtype: Link Rect: 70, 405, 147, 413 Annotation: Subtype: Link Rect: 118, 367, 204, 375 Annotation: Subtype: Link Rect: 97, 224, 165, 233 Annotation: Subtype: Link Rect: 390, 660, 476, 668 Annotation: Subtype: Link Rect: 386, 642, 489, 649 Annotation: Subtype: Link Rect: 451, 585, 536, 592 Annotation: Subtype: Link Rect: 386, 557, 466, 564 Annotation: Subtype: Link Rect: 410, 489, 499, 498 Annotation: Subtype: Link Rect: 331, 460, 421, 469 Annotation: Subtype: Link Rect: 410, 434, 483, 441 Annotation: Subtype: Link Rect: 442, 404, 541, 413 Annotation: Subtype: Link Rect: 458, 273, 484, 280 Annotation: Subtype: Link Rect: 484, 273, 516, 280 Annotation: Subtype: Link Rect: 515, 273, 551, 281 Annotation: Subtype: Link Rect: 304, 264, 327, 271 Annotation: Subtype: Link Rect: 327, 263, 354, 271 Annotation: Subtype: Link Rect: 43, 29, 111, 37 Annotation: Subtype: Link Rect: 114, 29, 174, 37 Annotation: Subtype: Link Rect: 433, 29, 551, 38 Checksum: 5e57513b Type: CRC32 Checksum: af7cd886b99554615ec4b4b2e64b1161 Type: MD5 Checksum: 3a7f53bee777e47a87fe2b54cb7ee0cfc5364f26 Type: SHA-1