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     Item: 
      Title: Study of CD27, CD38, HLA-DR and Ki-67 immune profiles for the characterization of active tuberculosis, latent infection and end of treatment
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        Title: Introduction
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Study population and inclusion criteria
         Item: 
          Title: PBMCs isolation, preservation, and thawing
         Item: 
          Title: PBMCs stimulation with mycobacterial antigen
         Item: 
          Title: Extracellular and intracellular staining and acquisition in flow cytometer
         Item: 
          Title: Flow cytometry data analysis
         Item: 
          Title: Statistics
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Expression of CD27, CD38, HLA-DR and Ki-67 markers on Mtb-specific CD4+ T-cells differs in LTBI individuals and anti-TB treated patients compared to aTB patients
         Item: 
          Title: CD27 MFI ratio provides a useful tool to characterize aTB
         Item: 
          Title: Ki-67+ and HLA-DR+ populations yield the highest discriminative performance
         Item: 
          Title: Multiparametric analyses reveal the presence of cell subsets with significant differences in abundance in aTB patients before and after treatment
       Item: 
        Title: Discussion
       Item: 
        Title: Data availability statement
       Item: 
        Title: Ethics statement
       Item: 
        Title: Author contributions
       Item: 
        Title: Funding
       Item: 
        Title: Conflict of interest
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        Title: Publisher’s note
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      Title: References
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  Checksum: 7227ef7d7115acd07ecaa3533cc0aabba706fff6
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