79b83cea37ffd3b063f7914d750c3a78 pmc_9394466.pdf e8692123d589d368c16df997a1c9290a8d21199f pmc_9394466.pdf 1ac175c3c2ecc4b26ef4d65694ad4b222b37d50a897802c1e166506e6dd49161 pmc_9394466.pdf Title: Vaccination and Antibody Testing in Cats Subject: Vaccines protect cats from serious diseases by inducing antibodies and cellular immune responses. Primary vaccinations and boosters are given according to vaccination guidelines provided by industry and veterinary organizations, based on minimal duration of immunity (DOI). For certain diseases, particularly feline panleukopenia, antibody titres correlate with protection. For feline calicivirus and feline herpesvirus, a similar correlation is absent, or less clear. In this review, the European Advisory Board on Cat Diseases (ABCD) presents current knowledge and expert opinion on the use of antibody testing in different situations. Antibody testing can be performed either in diagnostic laboratories, or in veterinary practice using point of care (POC) tests, and can be applied for several purposes, such as to provide evidence that a successful immune response was induced following vaccination. In adult cats, antibody test results can inform the appropriate re-vaccination interval. In shelters, antibody testing can support the control of FPV outbreaks by identifying potentially unprotected cats. Antibody testing has also been proposed to support decisions on optimal vaccination schedules for the individual kitten. However, such testing is still expensive and it is considered impractical to monitor the decline of maternally derived antibodies. Keywords: feline; titre testing; vaccine; immunization; maternal antibodies; duration of immunity; DOI Author: Herman Egberink, Tadeusz Frymus, Katrin Hartmann, Karin Möstl, Diane D. Addie, Sándor Belák, Corine Boucraut-Baralon, Regina Hofmann-Lehmann, Albert Lloret, Fulvio Marsilio, Maria Grazia Pennisi, Séverine Tasker, Etienne Thiry, Uwe Truyen and Margaret J. Hosie Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Jul 29 04:51:21 2022 CEST ModDate: Fri Jul 29 09:42:06 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 277894 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GIFXFT+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 IODWWR+VnURWPalladioL Type 1 Custom yes yes no 15 0 LGJEAX+URWPalladioL-Bold Type 1 Custom yes yes no 19 0 MCNWUJ+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 BBPQKR+URWPalladioL-Ital Type 1 Custom yes yes no 28 0 HOWKDX+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 46 0 PDTLUH+CMSY10 Type 1 Builtin yes yes no 74 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-01-10 02:31:43 CET RepresentationInformation: pmc_9394466.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-12-14 02:17:49 CET Size: 277894 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 242 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4923ab24 Item: Title: Antibodies and Protection against FPV Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Children: Item: Title: Gold Standard Tests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Point-of-Care (POC) Test Kits Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Applications of POC Antibody Testing against FPV Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Children: Item: Title: To Measure the FPV Antibody Response in Kittens Following Vaccination Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: To Test Whether (Re)Vaccination for FPV Is Necessary Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: To Control FPV Infection and Disease Outbreak in Shelters Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: To Determine the Optimal Age of Primary Vaccination for FPV in Kittens Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Children: Item: Title: Acquisition of FPV MDAs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Duration of Protection by MDAs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Active Immunization in Early Life Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Info: Title: Vaccination and Antibody Testing in Cats Author: Herman Egberink, Tadeusz Frymus, Katrin Hartmann, Karin Möstl, Diane D. Addie, Sándor Belák, Corine Boucraut-Baralon, Regina Hofmann-Lehmann, Albert Lloret, Fulvio Marsilio, Maria Grazia Pennisi, Séverine Tasker, Etienne Thiry, Uwe Truyen and Margaret J. Hosie Subject: Vaccines protect cats from serious diseases by inducing antibodies and cellular immune responses. Primary vaccinations and boosters are given according to vaccination guidelines provided by industry and veterinary organizations, based on minimal duration of immunity (DOI). For certain diseases, particularly feline panleukopenia, antibody titres correlate with protection. For feline calicivirus and feline herpesvirus, a similar correlation is absent, or less clear. In this review, the European Advisory Board on Cat Diseases (ABCD) presents current knowledge and expert opinion on the use of antibody testing in different situations. Antibody testing can be performed either in diagnostic laboratories, or in veterinary practice using point of care (POC) tests, and can be applied for several purposes, such as to provide evidence that a successful immune response was induced following vaccination. In adult cats, antibody test results can inform the appropriate re-vaccination interval. In shelters, antibody testing can support the control of FPV outbreaks by identifying potentially unprotected cats. Antibody testing has also been proposed to support decisions on optimal vaccination schedules for the individual kitten. However, such testing is still expensive and it is considered impractical to monitor the decline of maternally derived antibodies. 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