f9947861222769fb5b4f06723db1e943 pmc_9508125.pdf 0b94a34f66bf4a32c0d1981235620ba893c87e32 pmc_9508125.pdf 23027f460fd70e68b146fa1e94cb376e3e675dacb61cb66c64e1771d9c7e6ab1 pmc_9508125.pdf Title: The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases Subject: Nature Communications, doi:10.1038/s41467-022-33180-5 Keywords: Author: Sukanya Luang Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Wed Sep 21 12:38:27 2022 CEST ModDate: Fri Sep 23 11:56:46 2022 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 19 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 5928009 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EIEOAH+AdvOT0c200bf0 Type 1C WinAnsi yes yes no 753 0 EIENNF+AdvOTcc1f6510.I Type 1C WinAnsi yes yes no 22 0 EIEOAI+AdvOT0c200bf0+fb Type 1C Custom yes yes yes 754 0 EIENOG+AdvOTdd63dae3+20 Type 1C WinAnsi yes yes no 23 0 EIENOH+AdvOTdd63dae3+22 Type 1C Custom yes yes yes 24 0 EIEMGI+AdvOT13119950 Type 1C WinAnsi yes yes no 25 0 EIEMGJ+AdvOT89719618 Type 1C WinAnsi yes yes no 26 0 EIEMGK+AdvOTa2fa4214.B Type 1C WinAnsi yes yes no 1167 0 EIENNC+AdvOTdd63dae3 Type 1C WinAnsi yes yes no 29 0 EIEODI+AdvOT511ca30e.B Type 1C WinAnsi yes yes no 30 0 EIENND+AdvOTdd63dae3+03 Type 1C Custom yes yes yes 31 0 EIENNE+AdvOTdd63dae3+fb Type 1C Custom yes yes yes 33 0 EIEOII+Arial-BoldMT Type 1C WinAnsi yes yes no 27 0 EIEPLC+AdvOT3d287b35.B Type 1C WinAnsi yes yes no 28 0 EIEOGI+ArialMT Type 1C Custom yes yes yes 32 0 EIEPMC+AdvOT70e1938e Type 1C WinAnsi yes yes no 164 0 EIEPND+AdvOT70e1938e+fb Type 1C Custom yes yes yes 165 0 EIEPPD+AdvOT401859e4.I Type 1C WinAnsi yes yes no 174 0 EIEPPE+AdvOT70e1938e+03 Type 1C Custom yes yes yes 175 0 EIFOHN+AdvOT3d287b35.B+03 Type 1C Custom yes yes yes 259 0 EIFOBO+SymbolMT Type 1C Custom yes yes no 260 0 EIGCCI+AdvOTcc1f6510.I+fb Type 1C Custom yes yes yes 355 0 EIGNGE+Arial-ItalicMT Type 1C WinAnsi yes yes no 415 0 EIGNOD+AdvOT8608a8d1 Type 1C WinAnsi yes yes no 583 0 EIGNOC+AdvOTdd63dae3+02 Type 1C MacRoman yes yes no 584 0 EIGODD+AdvOT23e3f5cb.I Type 1C WinAnsi yes yes no 755 0 EIGODE+AdvOT0c200bf0+20 Type 1C WinAnsi yes yes no 756 0 EIGODC+AdvOT0c200bf0+03 Type 1C Custom yes yes yes 757 0 EIGOID+AdvOT8608a8d1+22 Type 1C Custom yes yes yes 772 0 EIGOJD+AdvOT13119950+20 Type 1C WinAnsi yes yes no 799 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-01 02:41:07 CEST RepresentationInformation: pmc_9508125.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-10-06 02:16:00 CEST Size: 5928009 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR2' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR8' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR12' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR14' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR15' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR14' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR26' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR27' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR30' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR30' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR27' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR14' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR15' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR33' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR34' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR2' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR35' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR36' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR38' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR39' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR40' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR34' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR42' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR43' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR44' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR45' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR46' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR47' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR48' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR2' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR47' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR2' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR35' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR36' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR49' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR53' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR54' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR55' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR56' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR57' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR58' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR59' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR60' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR59' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR60' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR59' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR59' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR61' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR62' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR63' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR60' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR64' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR64' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR65' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR66' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR67' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR2' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR66' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR68' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR69' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR70' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR71' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR72' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR73' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR67' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR74' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR75' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR76' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR77' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR78' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR79' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR80' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR76' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR77' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR79' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR81' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR82' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR83' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR84' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR85' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR90' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR91' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR92' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR93' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR94' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR83' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR82' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR95' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR2' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR96' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR97' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR76' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR77' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR98' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR78' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR99' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR55' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR98' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR100' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR102' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR103' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR104' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR105' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR106' cannot be found Offset: 5379386 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR107' cannot be found Offset: 5379386 MIMEtype: application/pdf PDFMetadata: Objects: 1302 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-„hydrolases Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Children: Item: Title: Mutants altered in Trp286 and Trp434 residues Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Substrate specificity of WT, and Trp286 and Trp434 mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Steady-state kinetic constants of WT, and Trp286 and Trp434 mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Inhibition constants Ki of WT, and Trp286 and Trp434 mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: WT and mutant HvExoI:thio-β-d-glucoside complexes reveal the details of binding at the atomic level Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: G2SG-OMe binding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: 4NP-G3SG and 4NP-G3SG3OG binding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: G4SG-OMe and G4SG4OG4SG4OG4SG binding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: G6SG-OMe binding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Conformational behaviour of S- and O-nobreaklinked β-d-glucosides Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Binding and hydrolysis of the G4OG3OG natural substrate were explored via cMD and QM/MM MD metadynamics simulations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Binding and displacements of laminaritriose (G3OG3OG) and laminarihexaose (G3OG3OG3OG3OG3OG) hydrolytic products Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Glc displacement route (egress) or substrate-product assisted processivity in WT Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Children: Item: Title: Generation of HvExoI mutants, protein expression, and purification Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Enzyme stability, substrate specificity, kinetic analyses, and inhibition Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Protein crystallisation and ligand perfusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Crystal structure determination Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: cMD simulations of Michaelis complexes derived from thio-ligand complexes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: cMD simulations of the Michaelis complex with a natural substrate G4OG3OG bound to WT and W434A, based on the WT:G4SG4OG4S complex Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: QM/MM MD metadynamics simulations of G3OG and G4OG3OG substrates in WT Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Analyses of cMD and QM/MM MD metadynamics simulations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: cMD simulations of laminaritriose or laminarihexaose hydrolysis products by WT and the W434H and W434A mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: GaMD simulations of laminaritriose and laminarihexaose hydrolysis products by WT, and the W434H and W434A mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: GpathFinder simulations to explore Glc displacement routes in WT, and the W434H and W434A HvExoI mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Unconstrained MD simulations to explore sliding of substrates in WT, and the W434H and W434A HvExoI mutants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: Reporting summary Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Data availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Code availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Additional information Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Info: Title: The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases Author: Sukanya Luang Subject: Nature Communications, doi:10.1038/s41467-022-33180-5 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Wed Sep 21 13:08:27 CEST 2022 ModDate: Fri Sep 23 11:56:46 CEST 2022 ID: 0x9a3863de1e48dd33d1fa0d7eb82fba9c, 0x16d63372b3d366042935d0b3677f53b3 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 46 ImageHeight: 40 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 627 ImageHeight: 152 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 127 ImageHeight: 600 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 127 ImageHeight: 600 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 627 ImageHeight: 450 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 627 ImageHeight: 152 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 627 ImageHeight: 450 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1979 ImageHeight: 1244 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1963 ImageHeight: 1250 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1984 ImageHeight: 1349 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1984 ImageHeight: 1031 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1177 ImageHeight: 1977 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1748 ImageHeight: 1315 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1479 ImageHeight: 1409 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1730 ImageHeight: 353 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Fonts: Type1: Font: BaseFont: EIFOHN+AdvOT3d287b35.B+03 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EIFOHN+AdvOT3d287b35.B+03 Flags: Symbolic FontBBox: -208, -197, 895, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIFOBO+SymbolMT FontSubset: true FirstChar: 2 LastChar: 3 FontDescriptor: FontName: EIFOBO+SymbolMT Flags: Symbolic FontBBox: 0, -220, 1113, 1005 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: EIGOID+AdvOT8608a8d1+22 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EIGOID+AdvOT8608a8d1+22 Flags: Symbolic FontBBox: 0, -322, 1218, 968 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIGNOD+AdvOT8608a8d1 FontSubset: true FirstChar: 181 LastChar: 181 FontDescriptor: FontName: EIGNOD+AdvOT8608a8d1 Flags: Nonsymbolic FontBBox: -62, -208, 927, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIGNOC+AdvOTdd63dae3+02 FontSubset: true FirstChar: 251 LastChar: 251 FontDescriptor: FontName: EIGNOC+AdvOTdd63dae3+02 Flags: Nonsymbolic FontBBox: -93, -208, 593, 781 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: EIEMGK+AdvOTa2fa4214.B FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: EIEMGK+AdvOTa2fa4214.B Flags: Serif, Nonsymbolic FontBBox: -125, -218, 989, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIENNF+AdvOTcc1f6510.I FontSubset: true FirstChar: 44 LastChar: 122 FontDescriptor: FontName: EIENNF+AdvOTcc1f6510.I Flags: Serif, Nonsymbolic FontBBox: -218, -218, 1020, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIENOG+AdvOTdd63dae3+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: EIENOG+AdvOTdd63dae3+20 Flags: Nonsymbolic FontBBox: -197, -125, 1322, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIENOH+AdvOTdd63dae3+22 FontSubset: true FirstChar: 2 LastChar: 21 FontDescriptor: FontName: EIENOH+AdvOTdd63dae3+22 Flags: Symbolic FontBBox: -62, -250, 1083, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIEMGI+AdvOT13119950 FontSubset: true FirstChar: 38 LastChar: 233 FontDescriptor: FontName: EIEMGI+AdvOT13119950 Flags: Nonsymbolic FontBBox: -31, -218, 947, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEMGJ+AdvOT89719618 FontSubset: true FirstChar: 35 LastChar: 124 FontDescriptor: FontName: EIEMGJ+AdvOT89719618 Flags: Nonsymbolic FontBBox: -20, -218, 927, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEOII+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: EIEOII+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEPLC+AdvOT3d287b35.B FontSubset: true FirstChar: 40 LastChar: 124 FontDescriptor: FontName: EIEPLC+AdvOT3d287b35.B Flags: Serif, Nonsymbolic FontBBox: -125, -218, 1000, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIENNC+AdvOTdd63dae3 FontSubset: true FirstChar: 37 LastChar: 246 FontDescriptor: FontName: EIENNC+AdvOTdd63dae3 Flags: Serif, Nonsymbolic FontBBox: -93, -218, 979, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEODI+AdvOT511ca30e.B FontSubset: true FirstChar: 48 LastChar: 57 FontDescriptor: FontName: EIEODI+AdvOT511ca30e.B Flags: Nonsymbolic FontBBox: -41, -218, 979, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIENND+AdvOTdd63dae3+03 FontSubset: true FirstChar: 1 LastChar: 8 FontDescriptor: FontName: EIENND+AdvOTdd63dae3+03 Flags: Symbolic FontBBox: -156, -197, 833, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIGNGE+Arial-ItalicMT FontSubset: true FirstChar: 97 LastChar: 118 FontDescriptor: FontName: EIGNGE+Arial-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIGOJD+AdvOT13119950+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: EIGOJD+AdvOT13119950+20 Flags: Nonsymbolic FontBBox: -229, -104, 1156, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEOGI+ArialMT FontSubset: true FirstChar: 2 LastChar: 197 FontDescriptor: FontName: EIEOGI+ArialMT Flags: Symbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIENNE+AdvOTdd63dae3+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EIENNE+AdvOTdd63dae3+fb Flags: Symbolic FontBBox: 19, 0, 812, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIGCCI+AdvOTcc1f6510.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EIGCCI+AdvOTcc1f6510.I+fb Flags: Symbolic FontBBox: -187, -208, 885, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIEPMC+AdvOT70e1938e FontSubset: true FirstChar: 40 LastChar: 122 FontDescriptor: FontName: EIEPMC+AdvOT70e1938e Flags: Serif, Nonsymbolic FontBBox: -114, -218, 989, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEPND+AdvOT70e1938e+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EIEPND+AdvOT70e1938e+fb Flags: Symbolic FontBBox: 9, 0, 854, 781 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIEPPD+AdvOT401859e4.I FontSubset: true FirstChar: 75 LastChar: 75 FontDescriptor: FontName: EIEPPD+AdvOT401859e4.I Flags: Nonsymbolic FontBBox: -229, -218, 1072, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEPPE+AdvOT70e1938e+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EIEPPE+AdvOT70e1938e+03 Flags: Symbolic FontBBox: -187, -197, 864, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIEOAH+AdvOT0c200bf0 FontSubset: true FirstChar: 38 LastChar: 252 FontDescriptor: FontName: EIEOAH+AdvOT0c200bf0 Flags: Nonsymbolic FontBBox: -10, -208, 906, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIEOAI+AdvOT0c200bf0+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EIEOAI+AdvOT0c200bf0+fb Flags: Symbolic FontBBox: 19, 0, 604, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EIGODD+AdvOT23e3f5cb.I FontSubset: true FirstChar: 45 LastChar: 122 FontDescriptor: FontName: EIGODD+AdvOT23e3f5cb.I Flags: Nonsymbolic FontBBox: -62, -208, 947, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIGODE+AdvOT0c200bf0+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: EIGODE+AdvOT0c200bf0+20 Flags: Nonsymbolic FontBBox: -229, -104, 1083, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EIGODC+AdvOT0c200bf0+03 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EIGODC+AdvOT0c200bf0+03 Flags: Symbolic FontBBox: -156, -177, 802, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdf doi:10.1038/s41467-022-33180-5 The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases Sukanya Luang Xavier Fernández-Luengo Alba Nin-Hill Victor A. Streltsov Julian G. Schwerdt Santiago Alonso-Gil James R. Ketudat Cairns Stéphanie Pradeau Sébastien Fort Jean-Didier Maréchal Laura Masgrau Carme Rovira Maria Hrmova Springer US Nature Communications, doi:10.1038/s41467-022-33180-5 Springer 2022-09-23T11:56:46+02:00 2022-09-21T16:08:27+05:30 2022-09-23T11:56:46+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) uuid:d0a70882-c6bb-47bc-81d8-4d95a5b5f799 uuid:19a93a92-91ce-463f-a802-44527027aea9 default 1 converted uuid:eade1599-9042-43cb-9181-da8ccdb50d0c converted to PDF/A-2b pdfToolbox 2022-09-21T16:09:23+05:30 2 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 480, 552, 482, 561 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 480, 552, 482, 561 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 489, 550, 490, 560 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 481, 550, 489, 560 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 489, 550, 491, 560 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 295, 539, 296, 548 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 295, 539, 296, 548 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 538, 305, 547 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 295, 538, 304, 547 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 304, 538, 305, 547 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 320, 527, 322, 536 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 320, 527, 322, 536 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 329, 525, 330, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 321, 525, 329, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 329, 525, 331, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 420, 527, 422, 536 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 420, 527, 422, 536 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 429, 525, 430, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 421, 525, 429, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 429, 525, 431, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 501, 527, 503, 536 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 501, 527, 503, 536 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 510, 525, 511, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 502, 525, 510, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 510, 525, 512, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 307, 514, 309, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 307, 514, 309, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 316, 512, 317, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 307, 512, 316, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 316, 512, 317, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 389, 514, 391, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 389, 514, 391, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 398, 512, 399, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 390, 512, 398, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 398, 512, 400, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 472, 514, 474, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 472, 514, 474, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 481, 512, 482, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 472, 512, 481, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 481, 512, 482, 522 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 277, 501, 279, 510 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 277, 501, 279, 510 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 286, 500, 287, 509 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 277, 500, 286, 509 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 286, 500, 287, 509 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 220, 180, 222, 185 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 225, 180, 228, 185 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 236, 169, 239, 174 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 550, 169, 552, 174 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 554, 169, 557, 174 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 558, 169, 561, 174 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 325, 154, 328, 163 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 487, 105, 489, 110 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 491, 105, 493, 110 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 494, 105, 497, 110 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: -2, 479, 50, 511 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 38, 486, 50, 518 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 38, 490, 40, 500 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 38, 490, 40, 500 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 265, 48, 372, 55 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 278, 52, 281, 57 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 282, 52, 285, 57 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 440, 84, 443, 89 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 480, 73, 482, 78 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 485, 73, 488, 78 Flags: Print AppearanceDictionary: true Destination: 679 Thumb: true Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 245, 726, 248, 731 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 242, 716, 244, 721 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 216, 705, 221, 710 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 83, 662, 87, 667 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 156, 662, 161, 667 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 254, 662, 259, 667 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 233, 651, 238, 656 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 230, 641, 234, 646 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 224, 630, 229, 635 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 244, 576, 249, 581 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 112, 566, 117, 571 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 223, 566, 228, 571 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 214, 534, 219, 539 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 68, 523, 73, 528 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 74, 523, 80, 528 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 146, 512, 150, 517 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 72, 491, 74, 496 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 77, 491, 80, 496 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 81, 491, 86, 496 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 258, 427, 264, 431 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 211, 405, 216, 410 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 48, 384, 53, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 67, 352, 72, 356 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 75, 352, 80, 356 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 85, 309, 88, 314 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 89, 309, 95, 314 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 136, 298, 142, 303 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 287, 298, 292, 303 Flags: Print AppearanceDictionary: true Destination: 758 Annotation: Subtype: Link Rect: 110, 287, 115, 292 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 208, 287, 214, 292 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 215, 287, 220, 292 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 221, 287, 227, 292 Flags: Print AppearanceDictionary: true Destination: 758 Annotation: Subtype: Link Rect: 108, 277, 112, 281 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 114, 277, 119, 281 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 204, 277, 210, 281 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 94, 255, 100, 260 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 104, 223, 110, 228 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 113, 223, 118, 228 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 119, 223, 124, 228 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 127, 223, 133, 228 Flags: Print AppearanceDictionary: true Destination: 758 Annotation: Subtype: Link Rect: 134, 223, 139, 228 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 380, 587, 382, 592 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 385, 587, 388, 592 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 408, 583, 411, 591 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 479, 566, 484, 571 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 423, 551, 426, 559 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 403, 540, 406, 548 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 345, 523, 350, 528 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 351, 523, 355, 528 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 357, 523, 362, 528 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 396, 497, 399, 505 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 414, 491, 417, 496 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 384, 448, 389, 453 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 390, 448, 396, 453 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 425, 444, 429, 452 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 501, 390, 505, 398 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 398, 304, 403, 313 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 407, 304, 412, 313 Flags: Print AppearanceDictionary: true Destination: 216 Thumb: true Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 393, 58, 397, 66 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 402, 58, 406, 66 Flags: Print AppearanceDictionary: true Destination: 216 Thumb: true Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 59, 292, 64, 300 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 71, 296, 76, 301 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 64, 206, 69, 214 Flags: Print AppearanceDictionary: true Destination: 183 Annotation: Subtype: Link Rect: 80, 206, 85, 214 Flags: Print AppearanceDictionary: true Destination: 216 Annotation: Subtype: Link Rect: 206, 128, 209, 133 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 223, 59, 227, 67 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 237, 59, 242, 67 Flags: Print AppearanceDictionary: true Destination: 183 Annotation: Subtype: Link Rect: 252, 59, 256, 67 Flags: Print AppearanceDictionary: true Destination: 216 Annotation: Subtype: Link Rect: 385, 315, 390, 323 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 480, 202, 483, 207 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 414, 144, 419, 152 Flags: Print AppearanceDictionary: true Destination: 183 Annotation: Subtype: Link Rect: 403, 58, 407, 66 Flags: Print AppearanceDictionary: true Destination: 183 Thumb: true Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 264, 326, 268, 334 Flags: Print AppearanceDictionary: true Destination: 216 Annotation: Subtype: Link Rect: 270, 219, 274, 227 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 283, 219, 287, 227 Flags: Print AppearanceDictionary: true Destination: 183 Annotation: Subtype: Link Rect: 39, 208, 44, 216 Flags: Print AppearanceDictionary: true Destination: 216 Thumb: true Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 230, 390, 234, 398 Flags: Print AppearanceDictionary: true Destination: 233 Annotation: Subtype: Link Rect: 170, 358, 175, 366 Flags: Print AppearanceDictionary: true Destination: 233 Annotation: Subtype: Link Rect: 224, 212, 229, 217 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 231, 212, 236, 217 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 256, 101, 260, 109 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 252, 73, 254, 78 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 93, 47, 98, 56 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 326, 326, 331, 334 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 373, 272, 378, 281 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 546, 240, 551, 248 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 388, 197, 393, 206 Flags: Print AppearanceDictionary: true Destination: 266 Thumb: true Page: Label: 8 Thumb: true Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 103, 373, 109, 378 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 165, 326, 169, 334 Flags: Print AppearanceDictionary: true Destination: 339 Annotation: Subtype: Link Rect: 173, 326, 177, 334 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 174, 251, 178, 259 Flags: Print AppearanceDictionary: true Destination: 339 Annotation: Subtype: Link Rect: 188, 251, 193, 259 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 274, 112, 279, 120 Flags: Print AppearanceDictionary: true Destination: 339 Annotation: Subtype: Link Rect: 287, 112, 292, 120 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 439, 711, 443, 720 Flags: Print AppearanceDictionary: true Destination: 339 Annotation: Subtype: Link Rect: 451, 711, 456, 720 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 470, 594, 474, 602 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 465, 544, 470, 549 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 427, 384, 432, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 435, 384, 440, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 441, 384, 447, 389 Flags: Print AppearanceDictionary: true Destination: 758 Annotation: Subtype: Link Rect: 449, 384, 454, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 455, 384, 460, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 499, 330, 505, 335 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 506, 330, 511, 335 Flags: Print AppearanceDictionary: true Destination: 758 Annotation: Subtype: Link Rect: 512, 330, 518, 335 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 519, 330, 525, 335 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 367, 319, 372, 324 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 373, 319, 378, 324 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 380, 319, 385, 324 Flags: Print AppearanceDictionary: true Destination: 758 Annotation: Subtype: Link Rect: 386, 319, 391, 324 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 489, 287, 494, 292 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 439, 240, 443, 248 Flags: Print AppearanceDictionary: true Destination: 393 Annotation: Subtype: Link Rect: 507, 159, 509, 164 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 511, 159, 514, 164 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 398, 112, 401, 120 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 435, 112, 440, 120 Flags: Print AppearanceDictionary: true Destination: 393 Thumb: true Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 127, 101, 130, 109 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 396, 240, 399, 248 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 530, 223, 535, 228 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 442, 208, 445, 216 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 365, 202, 368, 207 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 399, 169, 405, 174 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 244, 287, 249, 292 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 218, 154, 222, 163 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 227, 154, 232, 163 Flags: Print AppearanceDictionary: true Destination: 216 Annotation: Subtype: Link Rect: 523, 277, 527, 281 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 388, 244, 394, 249 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 395, 244, 401, 249 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 405, 165, 409, 173 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 414, 165, 419, 173 Flags: Print AppearanceDictionary: true Destination: 216 Annotation: Subtype: Link Rect: 493, 84, 498, 89 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 458, 95, 464, 99 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 385, 62, 390, 67 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 483, 52, 488, 57 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 71, 197, 73, 201 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 75, 197, 77, 201 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 209, 177, 210, 181 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 212, 177, 214, 181 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 133, 127, 137, 131 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 330, 177, 334, 181 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 13 Annotations: Annotation: Subtype: Link Rect: 206, 679, 211, 687 Flags: Print AppearanceDictionary: true Destination: 233 Annotation: Subtype: Link Rect: 287, 651, 292, 656 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 71, 619, 74, 624 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 75, 619, 80, 624 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 81, 619, 87, 624 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 101, 598, 107, 603 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 110, 598, 115, 603 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 240, 551, 245, 559 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 58, 519, 63, 527 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 59, 433, 64, 441 Flags: Print AppearanceDictionary: true Destination: 266 Annotation: Subtype: Link Rect: 58, 180, 60, 185 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 61, 180, 64, 185 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 66, 180, 71, 185 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 117, 116, 122, 121 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 192, 116, 198, 121 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 527, 679, 532, 687 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 536, 647, 541, 655 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 334, 615, 339, 623 Flags: Print AppearanceDictionary: true Destination: 365 Annotation: Subtype: Link Rect: 426, 583, 430, 591 Flags: Print AppearanceDictionary: true Destination: 339 Annotation: Subtype: Link Rect: 435, 583, 440, 591 Flags: Print AppearanceDictionary: true Destination: 393 Annotation: Subtype: Link Rect: 529, 394, 535, 399 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 384, 283, 388, 291 Flags: Print AppearanceDictionary: true Destination: 393 Annotation: Subtype: Link Rect: 553, 266, 559, 271 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 402, 244, 407, 249 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 408, 244, 413, 249 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 447, 137, 452, 142 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 453, 137, 458, 142 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 460, 137, 466, 142 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 409, 52, 414, 57 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 415, 52, 421, 57 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 422, 52, 428, 57 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 14 Annotations: Annotation: Subtype: Link Rect: 249, 684, 253, 688 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 255, 684, 260, 688 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 75, 609, 81, 613 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 82, 609, 87, 613 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 253, 576, 258, 581 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 259, 576, 264, 581 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 119, 555, 124, 560 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 138, 544, 143, 549 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 272, 480, 277, 485 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 279, 480, 285, 485 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 286, 480, 292, 485 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 267, 416, 273, 421 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 86, 341, 92, 346 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 152, 148, 157, 153 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 75, 116, 81, 121 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 125, 116, 131, 121 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 70, 101, 105, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 111, 101, 127, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 132, 101, 147, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 152, 101, 170, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 175, 101, 190, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 213, 101, 228, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 279, 95, 282, 99 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 283, 95, 286, 99 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 287, 95, 292, 99 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 210, 84, 215, 89 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 242, 84, 248, 89 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 289, 84, 294, 89 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 354, 716, 360, 721 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 415, 641, 420, 646 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 421, 641, 426, 646 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 473, 641, 478, 646 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 493, 534, 498, 539 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 514, 508, 518, 516 Flags: Print AppearanceDictionary: true Destination: 166 Annotation: Subtype: Link Rect: 523, 508, 527, 516 Flags: Print AppearanceDictionary: true Destination: 216 Annotation: Subtype: Link Rect: 488, 433, 524, 441 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 444, 422, 480, 430 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 411, 412, 446, 420 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 393, 401, 434, 409 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 495, 330, 500, 335 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 493, 319, 498, 324 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 344, 309, 349, 314 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 516, 309, 521, 314 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 393, 255, 399, 260 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 520, 144, 556, 152 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 15 Annotations: Annotation: Subtype: Link Rect: 251, 716, 256, 721 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 139, 705, 145, 710 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 189, 705, 195, 710 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 105, 694, 111, 699 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 236, 694, 241, 699 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 176, 566, 181, 571 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 190, 555, 196, 560 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 197, 555, 202, 560 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 194, 427, 200, 431 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 237, 384, 242, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 171, 373, 177, 378 Flags: Print AppearanceDictionary: true Destination: 762 Annotation: Subtype: Link Rect: 254, 341, 259, 346 Flags: Print AppearanceDictionary: true Destination: 762 Annotation: Subtype: Link Rect: 70, 309, 76, 314 Flags: Print AppearanceDictionary: true Destination: 762 Annotation: Subtype: Link Rect: 84, 287, 90, 292 Flags: Print AppearanceDictionary: true Destination: 762 Annotation: Subtype: Link Rect: 133, 277, 139, 281 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 172, 223, 177, 228 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 214, 169, 219, 174 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 184, 159, 190, 164 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 81, 148, 87, 153 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 63, 137, 68, 142 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 117, 137, 123, 142 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 349, 690, 384, 698 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 545, 690, 561, 698 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 679, 321, 687 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 498, 679, 537, 687 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 338, 662, 344, 667 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 470, 630, 472, 635 Flags: Print AppearanceDictionary: true Destination: 679 Annotation: Subtype: Link Rect: 473, 630, 476, 635 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 502, 594, 561, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 583, 359, 591 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 387, 512, 393, 517 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 505, 480, 510, 485 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 356, 469, 361, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 515, 469, 520, 474 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 511, 459, 517, 464 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 332, 384, 338, 389 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 553, 362, 559, 367 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 386, 266, 391, 271 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 432, 266, 437, 271 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 534, 112, 561, 120 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 101, 499, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 449, 73, 458, 78 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 460, 73, 468, 78 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 16 Annotations: Annotation: Subtype: Link Rect: 89, 705, 96, 710 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 286, 587, 294, 592 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 81, 437, 86, 442 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 220, 416, 228, 421 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 210, 122, 260, 131 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 111, 101, 128, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 148, 101, 164, 109 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 185, 90, 202, 98 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 216, 79, 233, 88 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 237, 79, 255, 88 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 274, 79, 292, 88 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 39, 58, 57, 66 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 78, 58, 96, 66 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 272, 47, 292, 56 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 733, 323, 741 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 327, 733, 341, 741 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 346, 733, 365, 741 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 385, 733, 405, 741 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 540, 722, 559, 730 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 711, 324, 720 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 329, 711, 347, 720 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 367, 711, 386, 720 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 517, 701, 534, 709 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 540, 701, 559, 709 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 690, 325, 698 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 345, 690, 363, 698 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 482, 679, 501, 687 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 505, 679, 522, 687 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 526, 679, 543, 687 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 669, 323, 677 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 399, 604, 529, 613 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 534, 604, 561, 613 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 594, 402, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 502, 598, 510, 603 Flags: Print AppearanceDictionary: true Destination: null Annotation: Subtype: Link Rect: 511, 598, 519, 603 Flags: Print AppearanceDictionary: true Destination: null Thumb: true Page: Label: 17 Thumb: true Page: Label: 18 Annotations: Annotation: Subtype: Link Rect: 434, 594, 516, 602 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 534, 326, 561, 334 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 328, 315, 540, 323 Flags: Print AppearanceDictionary: true Thumb: true Page: Label: 19 Annotations: Annotation: Subtype: Link Rect: 136, 529, 250, 537 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 61, 519, 94, 527 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 136, 487, 250, 495 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 61, 476, 93, 484 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 508, 465, 516 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 390, 421, 398 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 456, 219, 561, 227 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 208, 365, 216 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 74, 65, 181, 73 Flags: Print AppearanceDictionary: true Thumb: true Checksum: 370d7c04 Type: CRC32 Checksum: f9947861222769fb5b4f06723db1e943 Type: MD5 Checksum: 0b94a34f66bf4a32c0d1981235620ba893c87e32 Type: SHA-1