84ceac8242fe08917bd5a1f7da8d335b pmc_9557300.pdf 48f7aaf8faf1436fa6f0b997311e7044f78851bb pmc_9557300.pdf 8d4b9a117917d6b8f4092eef9f019111182e939632209f344397aa9eb97518f0 pmc_9557300.pdf Title: Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial Subject: Background: Post-stroke cognitive and emotional complications are frequent in the chronic stages of stroke and have important implications for the functionality and quality of life of those affected and their caregivers. Keywords: stroke, mindfulness, physical exercise, computerized cognitive training, neuroimaging, biomarkers Author: Maria Mataró Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.16 CreationDate: Tue Sep 27 07:26:23 2022 CEST ModDate: Tue Sep 27 09:26:10 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1661432 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ZHCNEG+MinionPro-Regular Type 1 Custom yes yes no 21 0 TJNRBR+MuseoSans-700 Type 1 Custom yes yes no 22 0 JUVYUT+MuseoSans-300 Type 1 Custom yes yes no 23 0 XIZUJH+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 28 0 DZAQQE+MuseoSans-300Italic Type 1 Custom yes yes no 29 0 BCLPPQ+MuseoSans-500 Type 1 Custom yes yes no 30 0 GLYSYL+MinionPro-Bold Type 1 Custom yes yes no 215 0 JFRSVQ+MTSYN Type 1 Builtin yes yes no 343 0 RNMPIC+Dingbats Type 1 Builtin yes yes no 354 0 NIJUPK+MinionPro-It Type 1 Custom yes yes no 630 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-27 02:37:16 CEST RepresentationInformation: pmc_9557300.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-09-25 02:20:01 CEST Size: 1661432 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 993 FreeObjects: 79 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial Children: Item: Title: Introduction Item: Title: Aims of the study Item: Title: Materials and methods Children: Item: Title: Study oversight and schedule Item: Title: Deviation from the initial protocol Item: Title: Participants Item: Title: Recruitment and screening Item: Title: Assessments Item: Title: Randomization and blinding Item: Title: Interventions Children: Item: Title: Mindfulness-based stress reduction program Item: Title: Multicomponent physical exercise program Item: Title: Computerized cognitive training program Item: Title: Intervention adherence Item: Title: Safety considerations Item: Title: Tailoring participants' individual needs Item: Title: Data management and results Children: Item: Title: Confidentiality and access to data Item: Title: Baseline variables Item: Title: Outcome variables Children: Item: Title: Primary outcomes Children: Item: Title: Cognitive functioning Item: Title: Emotional wellbeing Item: Title: Secondary outcomes Children: Item: Title: Psychosocial and lifestyle measurements Item: Title: Anthropometric measures and physical fitness Item: Title: Brain magnetic resonance imaging Item: Title: Blood-sample and stool-sample data Item: Title: Exit qualitative interviews Item: Title: Analysis Children: Item: Title: Power analysis Item: Title: Statistical analysis Item: Title: Discussion Item: Title: Dissemination Item: Title: Ethics statement Item: Title: Author contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Conflict of interest Item: Title: Publisher's note Item: Title: Supplementary material Item: Title: References Info: Title: Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial Author: Maria Mataró Subject: Background: Post-stroke cognitive and emotional complications are frequent in the chronic stages of stroke and have important implications for the functionality and quality of life of those affected and their caregivers. Keywords: stroke, mindfulness, physical exercise, computerized cognitive training, neuroimaging, biomarkers Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.16 CreationDate: Tue Sep 27 07:56:23 CEST 2022 ModDate: Tue Sep 27 09:56:10 CEST 2022 ID: 0xf151e76495689364a88f5f0e62bb6650, 0x1145f9ee54e11942b89b8eb4763704a3 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: RNMPIC+Dingbats FontSubset: true FirstChar: 51 LastChar: 51 FontDescriptor: FontName: RNMPIC+Dingbats Flags: Symbolic FontBBox: -1, -143, 981, 819 FontFile: true Font: BaseFont: ZHCNEG+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 250 FontDescriptor: FontName: ZHCNEG+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: TJNRBR+MuseoSans-700 FontSubset: true FirstChar: 2 LastChar: 122 FontDescriptor: FontName: TJNRBR+MuseoSans-700 Flags: Symbolic FontBBox: -125, -210, 1126, 902 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: NIJUPK+MinionPro-It FontSubset: true FirstChar: 40 LastChar: 250 FontDescriptor: FontName: NIJUPK+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JUVYUT+MuseoSans-300 FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: JUVYUT+MuseoSans-300 Flags: Symbolic FontBBox: -118, -210, 1088, 883 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GLYSYL+MinionPro-Bold FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: GLYSYL+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JFRSVQ+MTSYN FontSubset: true FirstChar: 0 LastChar: 21 FontDescriptor: FontName: JFRSVQ+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: XIZUJH+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 134 LastChar: 134 FontDescriptor: FontName: XIZUJH+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -166, -214, 1050, 967 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: DZAQQE+MuseoSans-300Italic FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: DZAQQE+MuseoSans-300Italic Flags: Symbolic FontBBox: -245, -210, 1030, 883 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: BCLPPQ+MuseoSans-500 FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: BCLPPQ+MuseoSans-500 Flags: Symbolic FontBBox: -121, -210, 1088, 892 FontFile: true EncodingDictionary: Differences: true XMP: stroke, mindfulness, physical exercise, computerized cognitive training, neuroimaging, biomarkers pdfTeX-1.40.16 1.5 application/pdf fnagi-14-936077.tex Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial Background: Post-stroke cognitive and emotional complications are frequent in the chronic stages of stroke and have important implications for the functionality and quality of life of those affected and their caregivers. Maria Mataró stroke mindfulness physical exercise computerized cognitive training neuroimaging biomarkers 2022-09-27T10:56:23+05:30 2022-09-27T10:56:23+05:30 2022-09-27T12:56:10+05:30 2022-09-27T12:56:10+05:30 LaTeX with hyperref package uuid:0000541d-ce4c-44c4-8900-5f759b1dc462 uuid:13ee8cf4-bf3f-43f5-b510-95b455a4f8e3 Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 55, 784, 271, 800 Annotation: Subtype: Link Rect: 428, 791, 500, 801 Annotation: Subtype: Link Rect: 428, 782, 534, 792 Annotation: Subtype: Link Rect: 428, 772, 537, 783 Annotation: Subtype: Link Rect: 56, 689, 133, 706 Annotation: Subtype: Link Rect: 69, 196, 159, 205 Annotation: Subtype: Link Rect: 221, 511, 539, 706 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 327, 449, 421, 459 Annotation: Subtype: Link Rect: 262, 307, 287, 318 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 296, 76, 306 ActionDest: 711 Annotation: Subtype: Link Rect: 79, 296, 98, 306 ActionDest: 711 Annotation: Subtype: Link Rect: 213, 233, 243, 243 ActionDest: 711 Annotation: Subtype: Link Rect: 245, 233, 264, 243 ActionDest: 711 Annotation: Subtype: Link Rect: 218, 208, 262, 219 ActionDest: 768 Annotation: Subtype: Link Rect: 266, 208, 285, 219 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 196, 86, 206 ActionDest: 711 Annotation: Subtype: Link Rect: 88, 196, 107, 206 ActionDest: 711 Annotation: Subtype: Link Rect: 513, 298, 539, 309 ActionDest: 768 Annotation: Subtype: Link Rect: 307, 286, 331, 297 ActionDest: 768 Annotation: Subtype: Link Rect: 339, 286, 358, 297 ActionDest: 768 Annotation: Subtype: Link Rect: 476, 274, 539, 284 ActionDest: 768 Annotation: Subtype: Link Rect: 307, 261, 342, 272 ActionDest: 768 Annotation: Subtype: Link Rect: 346, 261, 365, 272 ActionDest: 768 Annotation: Subtype: Link Rect: 332, 224, 386, 235 ActionDest: 711 Annotation: Subtype: Link Rect: 392, 224, 411, 235 ActionDest: 711 Annotation: Subtype: Link Rect: 409, 199, 461, 210 ActionDest: 711 Annotation: Subtype: Link Rect: 465, 199, 485, 210 ActionDest: 711 Annotation: Subtype: Link Rect: 489, 199, 537, 210 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 187, 327, 197 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 176, 691, 215, 701 ActionDest: 768 Annotation: Subtype: Link Rect: 217, 691, 237, 701 ActionDest: 768 Annotation: Subtype: Link Rect: 142, 653, 186, 664 ActionDest: 711 Annotation: Subtype: Link Rect: 200, 653, 220, 664 ActionDest: 711 Annotation: Subtype: Link Rect: 75, 566, 136, 577 ActionDest: 711 Annotation: Subtype: Link Rect: 141, 566, 160, 577 ActionDest: 711 Annotation: Subtype: Link Rect: 190, 541, 255, 552 ActionDest: 711 Annotation: Subtype: Link Rect: 262, 541, 282, 552 ActionDest: 711 Annotation: Subtype: Link Rect: 87, 529, 148, 540 ActionDest: 768 Annotation: Subtype: Link Rect: 153, 529, 172, 540 ActionDest: 768 Annotation: Subtype: Link Rect: 58, 516, 100, 527 ActionDest: 768 Annotation: Subtype: Link Rect: 105, 516, 124, 527 ActionDest: 768 Annotation: Subtype: Link Rect: 89, 454, 111, 465 ActionDest: 768 Annotation: Subtype: Link Rect: 114, 454, 133, 465 ActionDest: 768 Annotation: Subtype: Link Rect: 118, 393, 167, 403 ActionDest: 768 Annotation: Subtype: Link Rect: 170, 393, 189, 403 ActionDest: 768 Annotation: Subtype: Link Rect: 192, 393, 214, 403 ActionDest: 768 Annotation: Subtype: Link Rect: 217, 393, 236, 403 ActionDest: 768 Annotation: Subtype: Link Rect: 58, 329, 102, 340 ActionDest: 768 Annotation: Subtype: Link Rect: 106, 329, 125, 340 ActionDest: 768 Annotation: Subtype: Link Rect: 158, 267, 222, 278 ActionDest: 711 Annotation: Subtype: Link Rect: 227, 267, 246, 278 ActionDest: 711 Annotation: Subtype: Link Rect: 212, 230, 260, 241 ActionDest: 768 Annotation: Subtype: Link Rect: 266, 230, 285, 241 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 217, 112, 228 ActionDest: 768 Annotation: Subtype: Link Rect: 117, 217, 137, 228 ActionDest: 768 Annotation: Subtype: Link Rect: 257, 168, 287, 178 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 155, 77, 166 ActionDest: 768 Annotation: Subtype: Link Rect: 81, 155, 101, 166 ActionDest: 768 Annotation: Subtype: Link Rect: 196, 155, 258, 166 ActionDest: 711 Annotation: Subtype: Link Rect: 262, 155, 282, 166 ActionDest: 711 Annotation: Subtype: Link Rect: 244, 143, 285, 153 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 131, 74, 141 ActionDest: 711 Annotation: Subtype: Link Rect: 207, 93, 260, 104 ActionDest: 768 Annotation: Subtype: Link Rect: 262, 93, 282, 104 ActionDest: 768 Annotation: Subtype: Link Rect: 426, 691, 481, 701 ActionDest: 711 Annotation: Subtype: Link Rect: 484, 691, 503, 701 ActionDest: 711 Annotation: Subtype: Link Rect: 507, 691, 539, 701 ActionDest: 768 Annotation: Subtype: Link Rect: 307, 679, 330, 689 ActionDest: 768 Annotation: Subtype: Link Rect: 335, 679, 354, 689 ActionDest: 768 Annotation: Subtype: Link Rect: 360, 679, 420, 689 ActionDest: 711 Annotation: Subtype: Link Rect: 425, 679, 445, 689 ActionDest: 711 Annotation: Subtype: Link Rect: 395, 653, 455, 664 ActionDest: 711 Annotation: Subtype: Link Rect: 461, 653, 480, 664 ActionDest: 711 Annotation: Subtype: Link Rect: 372, 642, 424, 652 ActionDest: 768 Annotation: Subtype: Link Rect: 429, 642, 449, 652 ActionDest: 768 Annotation: Subtype: Link Rect: 507, 628, 539, 639 ActionDest: 768 Annotation: Subtype: Link Rect: 307, 617, 328, 627 ActionDest: 768 Annotation: Subtype: Link Rect: 332, 617, 352, 627 ActionDest: 768 Annotation: Subtype: Link Rect: 483, 566, 537, 577 ActionDest: 768 Annotation: Subtype: Link Rect: 307, 554, 327, 564 ActionDest: 768 Annotation: Subtype: Link Rect: 517, 516, 539, 527 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 504, 368, 515 ActionDest: 711 Annotation: Subtype: Link Rect: 375, 504, 394, 515 ActionDest: 711 Annotation: Subtype: Link Rect: 442, 467, 495, 477 ActionDest: 768 Annotation: Subtype: Link Rect: 501, 467, 520, 477 ActionDest: 768 Annotation: Subtype: Link Rect: 310, 429, 380, 440 ActionDest: 711 Annotation: Subtype: Link Rect: 387, 429, 407, 440 ActionDest: 711 Annotation: Subtype: Link Rect: 477, 379, 539, 390 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 368, 326, 378 ActionDest: 711 Annotation: Subtype: Link Rect: 328, 368, 348, 378 ActionDest: 711 Annotation: Subtype: Link Rect: 413, 317, 490, 328 ActionDest: 768 Annotation: Subtype: Link Rect: 492, 317, 511, 328 ActionDest: 768 Annotation: Subtype: Link Rect: 339, 256, 406, 266 ActionDest: 768 Annotation: Subtype: Link Rect: 412, 256, 431, 266 ActionDest: 768 Annotation: Subtype: Link Rect: 348, 231, 417, 241 ActionDest: 768 Annotation: Subtype: Link Rect: 421, 231, 440, 241 ActionDest: 768 Annotation: Subtype: Link Rect: 485, 217, 537, 228 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 206, 327, 216 ActionDest: 711 Annotation: Subtype: Link Rect: 428, 93, 463, 104 ActionDest: 711 Annotation: Subtype: Link Rect: 465, 93, 484, 104 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 175, 740, 223, 751 ActionDest: 711 Annotation: Subtype: Link Rect: 226, 740, 245, 751 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 90, 88, 100 ActionDest: 239 Annotation: Subtype: Link Rect: 433, 549, 468, 560 ActionDest: 239 Annotation: Subtype: Link Rect: 448, 488, 489, 498 ActionDest: 711 Annotation: Subtype: Link Rect: 491, 488, 510, 498 ActionDest: 711 Annotation: Subtype: Link Rect: 318, 257, 404, 268 Annotation: Subtype: Link Rect: 506, 179, 537, 188 ActionDest: 328 Annotation: Subtype: Link Rect: 439, 164, 492, 175 ActionDest: 711 Annotation: Subtype: Link Rect: 498, 164, 517, 175 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 441, 141, 490, 151 ActionDest: 711 Annotation: Subtype: Link Rect: 496, 141, 516, 151 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 218, 445, 248, 456 ActionDest: 351 Annotation: Subtype: Link Rect: 465, 405, 509, 416 ActionDest: 711 Annotation: Subtype: Link Rect: 515, 405, 534, 416 ActionDest: 711 Annotation: Subtype: Link Rect: 484, 246, 515, 254 ActionDest: 711 Annotation: Subtype: Link Rect: 516, 246, 531, 254 ActionDest: 711 Annotation: Subtype: Link Rect: 488, 216, 539, 224 ActionDest: 711 Annotation: Subtype: Link Rect: 430, 206, 471, 214 ActionDest: 711 Annotation: Subtype: Link Rect: 472, 206, 488, 214 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Rotate: 90 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 451, 702, 480, 716 ActionDest: 768 Annotation: Subtype: Link Rect: 481, 702, 496, 716 ActionDest: 768 Annotation: Subtype: Link Rect: 361, 689, 394, 704 ActionDest: 768 Annotation: Subtype: Link Rect: 395, 689, 411, 704 ActionDest: 768 Annotation: Subtype: Link Rect: 466, 677, 494, 691 ActionDest: 768 Annotation: Subtype: Link Rect: 495, 677, 511, 691 ActionDest: 768 Annotation: Subtype: Link Rect: 421, 665, 444, 679 ActionDest: 711 Annotation: Subtype: Link Rect: 445, 665, 460, 679 ActionDest: 711 Annotation: Subtype: Link Rect: 360, 652, 393, 667 ActionDest: 768 Annotation: Subtype: Link Rect: 395, 652, 410, 667 ActionDest: 768 Annotation: Subtype: Link Rect: 396, 640, 456, 654 ActionDest: 768 Annotation: Subtype: Link Rect: 457, 640, 473, 654 ActionDest: 768 Annotation: Subtype: Link Rect: 400, 627, 460, 642 ActionDest: 768 Annotation: Subtype: Link Rect: 461, 627, 476, 642 ActionDest: 768 Annotation: Subtype: Link Rect: 455, 615, 483, 629 ActionDest: 768 Annotation: Subtype: Link Rect: 485, 615, 500, 629 ActionDest: 768 Annotation: Subtype: Link Rect: 391, 592, 437, 607 ActionDest: 711 Annotation: Subtype: Link Rect: 438, 592, 453, 607 ActionDest: 711 Annotation: Subtype: Link Rect: 444, 580, 470, 594 ActionDest: 768 Annotation: Subtype: Link Rect: 471, 580, 486, 594 ActionDest: 768 Annotation: Subtype: Link Rect: 444, 567, 470, 582 ActionDest: 768 Annotation: Subtype: Link Rect: 471, 567, 486, 582 ActionDest: 768 Annotation: Subtype: Link Rect: 445, 555, 458, 569 ActionDest: 768 Annotation: Subtype: Link Rect: 459, 555, 474, 569 ActionDest: 768 Annotation: Subtype: Link Rect: 436, 542, 448, 557 ActionDest: 768 Annotation: Subtype: Link Rect: 450, 542, 465, 557 ActionDest: 768 Annotation: Subtype: Link Rect: 58, 422, 125, 433 ActionDest: 711 Annotation: Subtype: Link Rect: 131, 422, 150, 433 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 410, 155, 421 ActionDest: 645 Annotation: Subtype: Link Rect: 200, 362, 252, 373 ActionDest: 711 Annotation: Subtype: Link Rect: 254, 362, 274, 373 ActionDest: 711 Annotation: Subtype: Link Rect: 175, 275, 234, 285 ActionDest: 711 Annotation: Subtype: Link Rect: 236, 275, 255, 285 ActionDest: 711 Annotation: Subtype: Link Rect: 137, 262, 236, 273 ActionDest: 645 Annotation: Subtype: Link Rect: 208, 214, 258, 225 ActionDest: 768 Annotation: Subtype: Link Rect: 263, 214, 282, 225 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 143, 703, 173, 718 ActionDest: 768 Annotation: Subtype: Link Rect: 174, 703, 189, 718 ActionDest: 768 Annotation: Subtype: Link Rect: 99, 683, 179, 692 ActionDest: 768 Annotation: Subtype: Link Rect: 181, 683, 196, 692 ActionDest: 768 Annotation: Subtype: Link Rect: 58, 648, 92, 659 ActionDest: 711 Annotation: Subtype: Link Rect: 93, 648, 108, 659 ActionDest: 711 Annotation: Subtype: Link Rect: 152, 638, 184, 650 ActionDest: 768 Annotation: Subtype: Link Rect: 185, 638, 200, 650 ActionDest: 768 Annotation: Subtype: Link Rect: 148, 559, 182, 573 ActionDest: 711 Annotation: Subtype: Link Rect: 183, 559, 199, 573 ActionDest: 711 Annotation: Subtype: Link Rect: 138, 546, 194, 561 ActionDest: 768 Annotation: Subtype: Link Rect: 195, 546, 211, 561 ActionDest: 768 Annotation: Subtype: Link Rect: 130, 511, 187, 526 ActionDest: 711 Annotation: Subtype: Link Rect: 188, 511, 204, 526 ActionDest: 711 Annotation: Subtype: Link Rect: 166, 499, 205, 513 ActionDest: 711 Annotation: Subtype: Link Rect: 206, 499, 221, 513 ActionDest: 711 Annotation: Subtype: Link Rect: 147, 477, 201, 491 ActionDest: 768 Annotation: Subtype: Link Rect: 202, 477, 217, 491 ActionDest: 768 Annotation: Subtype: Link Rect: 58, 454, 129, 465 ActionDest: 711 Annotation: Subtype: Link Rect: 130, 454, 145, 465 ActionDest: 711 Annotation: Subtype: Link Rect: 184, 444, 225, 456 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 432, 97, 443 ActionDest: 711 Annotation: Subtype: Link Rect: 98, 432, 114, 443 ActionDest: 711 Annotation: Subtype: Link Rect: 171, 419, 202, 434 ActionDest: 768 Annotation: Subtype: Link Rect: 203, 419, 218, 434 ActionDest: 768 Annotation: Subtype: Link Rect: 137, 409, 191, 421 ActionDest: 711 Annotation: Subtype: Link Rect: 192, 409, 207, 421 ActionDest: 711 Annotation: Subtype: Link Rect: 145, 364, 225, 376 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 352, 87, 363 ActionDest: 768 Annotation: Subtype: Link Rect: 88, 352, 103, 363 ActionDest: 768 Annotation: Subtype: Link Rect: 168, 332, 209, 344 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 320, 71, 330 ActionDest: 711 Annotation: Subtype: Link Rect: 146, 307, 176, 322 ActionDest: 711 Annotation: Subtype: Link Rect: 177, 307, 192, 322 ActionDest: 711 Annotation: Subtype: Link Rect: 164, 287, 225, 299 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 275, 80, 286 ActionDest: 768 Annotation: Subtype: Link Rect: 81, 275, 96, 286 ActionDest: 768 Annotation: Subtype: Link Rect: 99, 252, 157, 263 ActionDest: 768 Annotation: Subtype: Link Rect: 158, 252, 173, 263 ActionDest: 768 Annotation: Subtype: Link Rect: 58, 230, 140, 241 ActionDest: 711 Annotation: Subtype: Link Rect: 142, 230, 157, 241 ActionDest: 711 Annotation: Subtype: Link Rect: 76, 198, 121, 208 ActionDest: 711 Annotation: Subtype: Link Rect: 123, 198, 138, 208 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 55, 577, 162, 588 ActionDest: 645 Annotation: Subtype: Link Rect: 165, 577, 172, 588 ActionDest: 645 Annotation: Subtype: Link Rect: 218, 214, 260, 225 ActionDest: 768 Annotation: Subtype: Link Rect: 263, 214, 282, 225 ActionDest: 768 Annotation: Subtype: Link Rect: 104, 202, 181, 213 ActionDest: 711 Annotation: Subtype: Link Rect: 187, 202, 206, 213 ActionDest: 711 Annotation: Subtype: Link Rect: 85, 189, 192, 200 ActionDest: 768 Annotation: Subtype: Link Rect: 196, 189, 215, 200 ActionDest: 768 Annotation: Subtype: Link Rect: 96, 152, 131, 163 ActionDest: 768 Annotation: Subtype: Link Rect: 138, 152, 157, 163 ActionDest: 768 Annotation: Subtype: Link Rect: 519, 743, 539, 752 ActionDest: 768 Annotation: Subtype: Link Rect: 307, 735, 343, 743 ActionDest: 768 Annotation: Subtype: Link Rect: 345, 735, 363, 743 ActionDest: 768 Annotation: Subtype: Link Rect: 429, 537, 537, 547 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 523, 327, 534 ActionDest: 711 Annotation: Subtype: Link Rect: 504, 523, 539, 534 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 512, 328, 522 ActionDest: 711 Annotation: Subtype: Link Rect: 331, 512, 351, 522 ActionDest: 711 Annotation: Subtype: Link Rect: 479, 512, 539, 522 ActionDest: 711 Annotation: Subtype: Link Rect: 307, 499, 326, 509 ActionDest: 711 Annotation: Subtype: Link Rect: 328, 499, 348, 509 ActionDest: 711 Annotation: Subtype: Link Rect: 412, 362, 442, 372 ActionDest: 447 Annotation: Subtype: Link Rect: 311, 337, 354, 347 ActionDest: 711 Annotation: Subtype: Link Rect: 357, 337, 376, 347 ActionDest: 711 Annotation: Subtype: Link Rect: 459, 276, 498, 286 ActionDest: 768 Annotation: Subtype: Link Rect: 501, 276, 520, 286 ActionDest: 768 Annotation: Subtype: Link Rect: 439, 263, 481, 274 ActionDest: 711 Annotation: Subtype: Link Rect: 483, 263, 502, 274 ActionDest: 711 Annotation: Subtype: Link Rect: 493, 251, 522, 262 ActionDest: 477 Annotation: Subtype: Link Rect: 307, 164, 337, 175 ActionDest: 477 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 77, 103, 137, 113 ActionDest: 768 Annotation: Subtype: Link Rect: 141, 103, 160, 113 ActionDest: 768 Annotation: Subtype: Link Rect: 125, 90, 154, 101 ActionDest: 541 Annotation: Subtype: Link Rect: 365, 196, 399, 206 ActionDest: 591 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 232, 691, 261, 701 ActionDest: 591 Annotation: Subtype: Link Rect: 184, 577, 243, 588 ActionDest: 768 Annotation: Subtype: Link Rect: 250, 577, 270, 588 ActionDest: 768 Annotation: Subtype: Link Rect: 236, 352, 285, 362 ActionDest: 711 Annotation: Subtype: Link Rect: 55, 340, 75, 350 ActionDest: 711 Annotation: Subtype: Link Rect: 77, 340, 127, 350 ActionDest: 768 Annotation: Subtype: Link Rect: 129, 340, 149, 350 ActionDest: 768 Annotation: Subtype: Link Rect: 151, 340, 184, 350 ActionDest: 711 Annotation: Subtype: Link Rect: 186, 340, 205, 350 ActionDest: 711 Annotation: Subtype: Link Rect: 208, 340, 244, 350 ActionDest: 768 Annotation: Subtype: Link Rect: 246, 340, 265, 350 ActionDest: 768 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 375, 114, 539, 125 Annotation: Subtype: Link Rect: 307, 102, 482, 113 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 244, 689, 287, 698 Annotation: Subtype: Link Rect: 65, 681, 123, 690 Annotation: Subtype: Link Rect: 98, 645, 185, 654 Annotation: Subtype: Link Rect: 90, 611, 202, 618 Annotation: Subtype: Link Rect: 158, 573, 246, 582 Annotation: Subtype: Link Rect: 160, 517, 250, 526 Annotation: Subtype: Link Rect: 247, 455, 287, 463 Annotation: Subtype: Link Rect: 65, 447, 125, 454 Annotation: Subtype: Link Rect: 201, 418, 287, 427 Annotation: Subtype: Link Rect: 65, 411, 81, 418 Annotation: Subtype: Link Rect: 264, 382, 287, 391 Annotation: Subtype: Link Rect: 65, 374, 103, 383 Annotation: Subtype: Link Rect: 196, 319, 287, 327 Annotation: Subtype: Link Rect: 65, 311, 108, 318 Annotation: Subtype: Link Rect: 248, 243, 287, 251 Annotation: Subtype: Link Rect: 65, 236, 97, 243 Annotation: Subtype: Link Rect: 274, 215, 287, 223 Annotation: Subtype: Link Rect: 65, 208, 136, 215 Annotation: Subtype: Link Rect: 95, 179, 226, 188 Annotation: Subtype: Link Rect: 244, 159, 287, 168 Annotation: Subtype: Link Rect: 65, 151, 136, 160 Annotation: Subtype: Link Rect: 124, 132, 238, 140 Annotation: Subtype: Link Rect: 184, 103, 268, 112 Annotation: Subtype: Link Rect: 487, 697, 539, 706 Annotation: Subtype: Link Rect: 317, 691, 344, 697 Annotation: Subtype: Link Rect: 414, 662, 502, 670 Annotation: Subtype: Link Rect: 466, 641, 539, 650 Annotation: Subtype: Link Rect: 317, 633, 330, 641 Annotation: Subtype: Link Rect: 335, 599, 427, 606 Annotation: Subtype: Link Rect: 424, 549, 517, 558 Annotation: Subtype: Link Rect: 526, 502, 539, 510 Annotation: Subtype: Link Rect: 317, 494, 364, 502 Annotation: Subtype: Link Rect: 482, 474, 539, 483 Annotation: Subtype: Link Rect: 317, 466, 331, 475 Annotation: Subtype: Link Rect: 335, 430, 441, 439 Annotation: Subtype: Link Rect: 458, 402, 521, 411 Annotation: Subtype: Link Rect: 462, 382, 539, 391 Annotation: Subtype: Link Rect: 317, 376, 334, 382 Annotation: Subtype: Link Rect: 526, 334, 539, 343 Annotation: Subtype: Link Rect: 317, 327, 390, 335 Annotation: Subtype: Link Rect: 464, 298, 539, 307 Annotation: Subtype: Link Rect: 317, 291, 333, 299 Annotation: Subtype: Link Rect: 380, 252, 479, 261 Annotation: Subtype: Link Rect: 526, 223, 539, 231 Annotation: Subtype: Link Rect: 317, 216, 401, 223 Annotation: Subtype: Link Rect: 421, 167, 537, 176 Annotation: Subtype: Link Rect: 369, 132, 475, 140 Annotation: Subtype: Link Rect: 370, 103, 471, 112 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 448, 791, 539, 800 Annotation: Subtype: Link Rect: 73, 719, 185, 726 Annotation: Subtype: Link Rect: 133, 690, 242, 698 Annotation: Subtype: Link Rect: 182, 653, 265, 662 Annotation: Subtype: Link Rect: 165, 617, 242, 626 Annotation: Subtype: Link Rect: 180, 589, 287, 598 Annotation: Subtype: Link Rect: 185, 570, 281, 578 Annotation: Subtype: Link Rect: 83, 535, 171, 543 Annotation: Subtype: Link Rect: 56, 499, 161, 507 Annotation: Subtype: Link Rect: 208, 478, 287, 487 Annotation: Subtype: Link Rect: 64, 472, 76, 478 Annotation: Subtype: Link Rect: 198, 430, 287, 439 Annotation: Subtype: Link Rect: 64, 424, 80, 430 Annotation: Subtype: Link Rect: 56, 394, 128, 403 Annotation: Subtype: Link Rect: 191, 303, 284, 311 Annotation: Subtype: Link Rect: 125, 219, 235, 228 Annotation: Subtype: Link Rect: 83, 185, 175, 192 Annotation: Subtype: Link Rect: 335, 734, 441, 742 Annotation: Subtype: Link Rect: 388, 697, 481, 706 Annotation: Subtype: Link Rect: 308, 641, 382, 650 Annotation: Subtype: Link Rect: 464, 613, 539, 622 Annotation: Subtype: Link Rect: 317, 607, 325, 614 Annotation: Subtype: Link Rect: 408, 584, 499, 592 Annotation: Subtype: Link Rect: 501, 556, 539, 564 Annotation: Subtype: Link Rect: 317, 549, 349, 556 Annotation: Subtype: Link Rect: 470, 527, 532, 535 Annotation: Subtype: Link Rect: 481, 506, 539, 515 Annotation: Subtype: Link Rect: 317, 498, 358, 507 Annotation: Subtype: Link Rect: 526, 462, 539, 471 Annotation: Subtype: Link Rect: 317, 454, 382, 463 Annotation: Subtype: Link Rect: 388, 426, 497, 435 Annotation: Subtype: Link Rect: 446, 398, 537, 407 Annotation: Subtype: Link Rect: 526, 319, 539, 327 Annotation: Subtype: Link Rect: 317, 311, 393, 319 Annotation: Subtype: Link Rect: 481, 283, 539, 292 Annotation: Subtype: Link Rect: 317, 276, 344, 283 Annotation: Subtype: Link Rect: 475, 216, 504, 224 Annotation: Subtype: Link Rect: 503, 216, 539, 224 Annotation: Subtype: Link Rect: 305, 207, 340, 215 Annotation: Subtype: Link Rect: 340, 207, 366, 215 Annotation: Subtype: Link Rect: 366, 207, 392, 215 Annotation: Subtype: Link Rect: 55, 39, 161, 48 Annotation: Subtype: Link Rect: 491, 39, 539, 48 Checksum: d1d3fe87 Type: CRC32 Checksum: 84ceac8242fe08917bd5a1f7da8d335b Type: MD5 Checksum: 48f7aaf8faf1436fa6f0b997311e7044f78851bb Type: SHA-1