d89f2a312a36f734d7d8dbca37f19465 pmc_9617204.pdf 38884eae1047cb3811c495802a73242c274b3456 pmc_9617204.pdf 384e78309f90141725ed725aae3e9ec41e2897290f1a86525e456f7c24f9267c pmc_9617204.pdf Title: Protocol to generate a patient derived xenograft model of acquired resistance to immunotherapy in humanized mice Subject: STAR Protocols, 3 (2022) 101712. doi:10.1016/j.xpro.2022.101712 Author: Alex Martínez-Sabadell Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Wed Oct 26 21:16:26 2022 CEST ModDate: Wed Oct 26 21:26:02 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 602.986 x 782.986 pts Page rot: 0 File size: 2997785 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DFOAEC+AdvPSA5BC Type 1C WinAnsi yes yes no 435 0 DFOAED+AdvPSA5CD Type 1C WinAnsi yes yes no 437 0 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derived xenograft model of acquired resistance to immunotherapy in humanized mice Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Before you begin Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: Institutional permissions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Key resources table Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Materials and equipment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Step-by-step method details Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Children: Item: Title: CD34+ cells isolation from cord blood Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: PDX generation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Mice humanization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Generation of an acquired immunoresistance model in PDX Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Expected outcomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Limitations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Troubleshooting Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Problem 1 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Potential solution Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Problem 2 Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Potential solution Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Resource availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Children: Item: Title: Lead contact Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Materials availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Data and code availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Declaration of interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Info: Title: Protocol to generate a patient derived xenograft model of acquired resistance to immunotherapy in humanized mice Author: Alex Martínez-Sabadell Subject: STAR 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