1c8dd316a6487cf9f6da3e96f68ca155 pmc_9751391.pdf 9fd63f407391eb2eb033a835df49445e3163bc4a pmc_9751391.pdf 55d3540a0bf16f39f0c57e276c8b238c511d94fd75999f79c65f68a2b929baca pmc_9751391.pdf Title: New methods for the diagnosis and monitoring of cognitive function in patients with type 2 diabetes Subject: The presence of type 2 diabetes acts as an accelerator of cognitive impairment (mild cognitive impairment and later dementia), with a significant impact on the management of the disease and its complications Keywords: type 2 diabetes, mild cognitive impairment, dementia, retinal microperimetry, neuropsychological tests Author: Andreea Ciudin Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Sat Nov 26 04:06:17 2022 CET ModDate: Sat Nov 26 04:15:25 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.389 x 841.663 pts Page rot: 0 File size: 716917 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AGANMB+AdvTTd3a5f740 Type 1C WinAnsi yes yes no 297 0 AGANMC+AdvPSA18C Type 1C WinAnsi yes yes no 298 0 AGANMD+AdvTT9b12cd41 Type 1C WinAnsi yes yes no 299 0 AGANME+AdvTT9b12cd41+20 Type 1C WinAnsi yes yes no 300 0 AGANMF+AdvPSA323 Type 1C WinAnsi yes yes no 301 0 AGANMG+AdvTT9b12cd41+fb Type 1C Custom yes yes yes 302 0 AGANNH+AdvTT2c8ce45a Type 1C WinAnsi yes yes no 308 0 AGBAMG+AdvTTd168d80a.I Type 1C WinAnsi yes yes no 311 0 AGBBAI+AdvOTd877c31c+03 Type 1C Custom yes yes yes 155 0 AGBBAJ+AdvOT3f84ef53 Type 1C WinAnsi yes yes no 146 0 AGBBBK+AdvOT1ef757c0+22 Type 1C Custom yes yes yes 153 0 AGBBAF+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 147 0 AGBBAG+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 157 0 AGBBAH+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 154 0 AGBEBJ+AdvOTb1404cd8+20 Type 1C WinAnsi yes yes no 162 0 AGBEBK+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 159 0 AGBEBL+AdvTTd3a5f740+fb Type 1C Custom yes yes yes 164 0 AGBGGN+AdvTTd3a5f740+20 Type 1C WinAnsi yes yes no 174 0 AGBGHO+AdvTT58d178b9+03 Type 1C Custom yes yes yes 172 0 AGBGHP+AdvOT7d6df7ab.I+20 Type 1C WinAnsi yes yes no 173 0 AGBGJA+AdvOT1ef757c0+01 Type 1C MacRoman yes yes no 169 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-08-29 02:27:31 CEST RepresentationInformation: pmc_9751391.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-08-03 02:24:43 CEST Size: 716917 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B10' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B11' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B12' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B13' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B14' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B15' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B17' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B18' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B19' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B19' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B20' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B20' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B21' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B22' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B22' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B23' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B24' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B22' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B24' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B25' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B26' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B27' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B27' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B28' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B29' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B30' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B29' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B31' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B32' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B33' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B31' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B30' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B34' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B35' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B36' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B35' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B30' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B37' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B38' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B39' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B40' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B41' cannot be found Offset: 703366 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B40' cannot be found Offset: 703366 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 357 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: New methods for the diagnosis and monitoring of cognitive function in patients with type 2 diabetes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: 1 Introduction. State of the art Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Children: Item: Title: 1.1 Type 2 diabetes as risk factor and accelerator for cognitive impairment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: 1.2 Actual recommendation for screening for cognitive impairment in T2D patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: 1.2.1 The mini mental state examination test Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: 1.2.2. The Montreal cognitive assessment test Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: 1.2.3. Limitations of the actual recommended tests for screening Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: 2 New emerging methods for screening and monitoring of cognitive function Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Children: Item: Title: 2.1 Diabetes specific dementia risk score Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: 2.2 Retinal microperimetry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: 3 Concluding remarks Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Info: Title: New methods for the diagnosis and monitoring of cognitive function in patients with type 2 diabetes Author: Andreea Ciudin Subject: The presence of type 2 diabetes acts as an accelerator of cognitive impairment (mild cognitive impairment and later dementia), with a significant impact on the management of the disease and its complications Keywords: type 2 diabetes, mild cognitive impairment, dementia, retinal microperimetry, neuropsychological tests Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Sat Nov 26 04:06:17 CET 2022 ModDate: Sat Nov 26 04:15:25 CET 2022 ID: 0x463a42736627c36209693948fe417cc0, 0x72b625a16ce2994cbf661ed207596d15 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2919 ImageHeight: 577 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1935 ImageHeight: 956 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1181 ImageHeight: 1187 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: AGBEBJ+AdvOTb1404cd8+20 FontSubset: true FirstChar: 129 LastChar: 129 FontDescriptor: FontName: AGBEBJ+AdvOTb1404cd8+20 Flags: Nonsymbolic FontBBox: 0, -208, 968, 708 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBEBL+AdvTTd3a5f740+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: AGBEBL+AdvTTd3a5f740+fb Flags: Symbolic FontBBox: 0, 0, 906, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGANMB+AdvTTd3a5f740 FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: AGANMB+AdvTTd3a5f740 Flags: Serif, Nonsymbolic FontBBox: -52, -208, 916, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBGJA+AdvOT1ef757c0+01 FontSubset: true FirstChar: 245 LastChar: 245 FontDescriptor: FontName: AGBGJA+AdvOT1ef757c0+01 Flags: Serif, Nonsymbolic FontBBox: -20, -250, 947, 854 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: AGANMC+AdvPSA18C FontSubset: true FirstChar: 180 LastChar: 180 FontDescriptor: FontName: AGANMC+AdvPSA18C Flags: Nonsymbolic FontBBox: -156, -208, 1125, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGANMD+AdvTT9b12cd41 FontSubset: true FirstChar: 40 LastChar: 224 FontDescriptor: FontName: AGANMD+AdvTT9b12cd41 Flags: Serif, Nonsymbolic FontBBox: -52, -208, 906, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGANME+AdvTT9b12cd41+20 FontSubset: true FirstChar: 146 LastChar: 148 FontDescriptor: FontName: AGANME+AdvTT9b12cd41+20 Flags: Nonsymbolic FontBBox: -114, -166, 1010, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBGHO+AdvTT58d178b9+03 FontSubset: true FirstChar: 0 LastChar: 0 FontDescriptor: FontName: AGBGHO+AdvTT58d178b9+03 Flags: Symbolic FontBBox: -645, -354, 916, 895 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGANMF+AdvPSA323 FontSubset: true FirstChar: 180 LastChar: 180 FontDescriptor: FontName: AGANMF+AdvPSA323 Flags: Nonsymbolic FontBBox: -156, -239, 1104, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBGHP+AdvOT7d6df7ab.I+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: AGBGHP+AdvOT7d6df7ab.I+20 Flags: Nonsymbolic FontBBox: -156, -187, 1000, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGANMG+AdvTT9b12cd41+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AGANMG+AdvTT9b12cd41+fb Flags: Symbolic FontBBox: 0, 0, 854, 697 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGBGGN+AdvTTd3a5f740+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: AGBGGN+AdvTTd3a5f740+20 Flags: Nonsymbolic FontBBox: -114, -166, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBBAJ+AdvOT3f84ef53 FontSubset: true FirstChar: 101 LastChar: 101 FontDescriptor: FontName: AGBBAJ+AdvOT3f84ef53 Flags: Nonsymbolic FontBBox: -177, -291, 1083, 1000 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBBAF+AdvOT1ef757c0 FontSubset: true FirstChar: 37 LastChar: 252 FontDescriptor: FontName: AGBBAF+AdvOT1ef757c0 Flags: Serif, Nonsymbolic FontBBox: -20, -250, 947, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGANNH+AdvTT2c8ce45a FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: AGANNH+AdvTT2c8ce45a Flags: Serif, Nonsymbolic FontBBox: -52, -208, 947, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBAMG+AdvTTd168d80a.I FontSubset: true FirstChar: 46 LastChar: 116 FontDescriptor: FontName: AGBAMG+AdvTTd168d80a.I Flags: Serif, Nonsymbolic FontBBox: -145, -208, 968, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBBBK+AdvOT1ef757c0+22 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: AGBBBK+AdvOT1ef757c0+22 Flags: Symbolic FontBBox: -135, -166, 697, 916 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGBBAH+AdvOT1ef757c0+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: AGBBAH+AdvOT1ef757c0+20 Flags: Nonsymbolic FontBBox: -135, -187, 1010, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AGBBAI+AdvOTd877c31c+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AGBBAI+AdvOTd877c31c+03 Flags: Symbolic FontBBox: 0, -364, 854, 927 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGBBAG+AdvOT1ef757c0+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: AGBBAG+AdvOT1ef757c0+fb Flags: Symbolic FontBBox: 0, -10, 781, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AGBEBK+AdvOT7d6df7ab.I FontSubset: true FirstChar: 46 LastChar: 122 FontDescriptor: FontName: AGBEBK+AdvOT7d6df7ab.I Flags: Serif, Nonsymbolic FontBBox: -135, -250, 1000, 854 FontFile3: true Encoding: WinAnsiEncoding XMP: Acrobat Distiller 7.0 (Windows) type 2 diabetes, mild cognitive impairment, dementia, retinal microperimetry, neuropsychological tests 2022-11-26T11:06:17+08:00 2022-11-26T11:15:25+08:00 Arbortext Advanced Print Publisher 10.0.1306/W Unicode 2022-11-26T11:15:25+08:00 application/pdf New methods for the diagnosis and monitoring of cognitive function in patients with type 2 diabetes Andreea Ciudin Rafael Sim&oacute The presence of type 2 diabetes acts as an accelerator of cognitive impairment (mild cognitive impairment and later dementia), with a significant impact on the management of the disease and its complications type 2 diabetes mild cognitive impairment dementia retinal microperimetry neuropsychological tests uuid:e2859e69-9441-422b-8192-9519365459ef uuid:f6794d12-123c-40a5-adc0-21bfa3845446 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 222, 686, 526, 707 Annotation: Subtype: Link Rect: 222, 661, 492, 682 Annotation: Subtype: Link Rect: 222, 636, 464, 657 Annotation: Subtype: Link Rect: 222, 611, 369, 632 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Annotation: Subtype: Link Rect: 56, 691, 133, 706 Annotation: Subtype: Link Rect: 56, 521, 153, 528 Annotation: Subtype: Link Rect: 56, 503, 120, 510 Annotation: Subtype: Link Rect: 56, 349, 164, 356 Annotation: Subtype: Link Rect: 108, 308, 167, 315 Annotation: Subtype: Link Rect: 56, 299, 140, 306 Annotation: Subtype: Link Rect: 447, 793, 469, 800 Annotation: Subtype: Link Rect: 463, 784, 525, 791 Annotation: Subtype: Link Rect: 443, 774, 535, 781 Annotation: Subtype: Link Rect: 56, 782, 247, 799 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 124, 641, 128, 650 Destination: 86 Annotation: Subtype: Link Rect: 161, 516, 191, 525 Destination: 1 Annotation: Subtype: Link Rect: 197, 516, 201, 525 Destination: 86 Annotation: Subtype: Link Rect: 206, 516, 210, 525 Destination: 86 Annotation: Subtype: Link Rect: 276, 454, 280, 463 Destination: 86 Annotation: Subtype: Link Rect: 140, 404, 144, 413 Destination: 86 Annotation: Subtype: Link Rect: 149, 404, 157, 413 Destination: null Annotation: Subtype: Link Rect: 216, 329, 224, 338 Destination: null Annotation: Subtype: Link Rect: 476, 716, 485, 725 Destination: null Annotation: Subtype: Link Rect: 389, 679, 393, 688 Destination: 86 Annotation: Subtype: Link Rect: 508, 629, 517, 638 Destination: null Annotation: Subtype: Link Rect: 524, 629, 533, 638 Destination: null Annotation: Subtype: Link Rect: 479, 604, 487, 613 Destination: null Annotation: Subtype: Link Rect: 492, 604, 500, 613 Destination: null Annotation: Subtype: Link Rect: 432, 454, 440, 463 Destination: null Annotation: Subtype: Link Rect: 444, 454, 453, 463 Destination: null Annotation: Subtype: Link Rect: 312, 441, 320, 450 Destination: null Annotation: Subtype: Link Rect: 443, 339, 452, 348 Destination: null Annotation: Subtype: Link Rect: 443, 791, 538, 798 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 149, 654, 157, 663 Destination: null Annotation: Subtype: Link Rect: 168, 654, 177, 663 Destination: null Annotation: Subtype: Link Rect: 180, 629, 189, 638 Destination: null Annotation: Subtype: Link Rect: 133, 491, 142, 500 Destination: null Annotation: Subtype: Link Rect: 144, 449, 153, 458 Destination: null Annotation: Subtype: Link Rect: 127, 362, 136, 371 Destination: null Annotation: Subtype: Link Rect: 183, 262, 191, 271 Destination: null Annotation: Subtype: Link Rect: 198, 262, 206, 271 Destination: null Annotation: Subtype: Link Rect: 151, 162, 160, 171 Destination: null Annotation: Subtype: Link Rect: 141, 137, 149, 146 Destination: null Annotation: Subtype: Link Rect: 274, 124, 283, 133 Destination: null Annotation: Subtype: Link Rect: 267, 99, 276, 108 Destination: null Annotation: Subtype: Link Rect: 348, 500, 357, 509 Destination: null Annotation: Subtype: Link Rect: 348, 221, 356, 230 Destination: null Annotation: Subtype: Link Rect: 466, 221, 475, 230 Destination: null Annotation: Subtype: Link Rect: 494, 162, 502, 171 Destination: null Annotation: Subtype: Link Rect: 443, 791, 538, 798 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 197, 704, 205, 713 Destination: null Annotation: Subtype: Link Rect: 273, 704, 281, 713 Destination: null Annotation: Subtype: Link Rect: 108, 604, 117, 613 Destination: null Annotation: Subtype: Link Rect: 177, 529, 185, 538 Destination: null Annotation: Subtype: Link Rect: 423, 679, 431, 688 Destination: null Annotation: Subtype: Link Rect: 436, 679, 445, 688 Destination: null Annotation: Subtype: Link Rect: 447, 629, 477, 638 Destination: 56 Annotation: Subtype: Link Rect: 468, 566, 477, 575 Destination: null Annotation: Subtype: Link Rect: 457, 491, 465, 500 Destination: null Annotation: Subtype: Link Rect: 443, 791, 538, 798 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 224, 704, 233, 713 Destination: null Annotation: Subtype: Link Rect: 137, 629, 146, 638 Destination: null Annotation: Subtype: Link Rect: 188, 604, 196, 613 Destination: null Annotation: Subtype: Link Rect: 189, 579, 198, 588 Destination: null Annotation: Subtype: Link Rect: 59, 554, 68, 563 Destination: null Annotation: Subtype: Link Rect: 203, 504, 212, 513 Destination: null Annotation: Subtype: Link Rect: 166, 454, 175, 463 Destination: null Annotation: Subtype: Link Rect: 170, 354, 179, 363 Destination: null Annotation: Subtype: Link Rect: 443, 791, 538, 798 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 69, 602, 157, 609 Annotation: Subtype: Link Rect: 193, 575, 246, 582 Annotation: Subtype: Link Rect: 205, 548, 282, 555 Annotation: Subtype: Link Rect: 164, 513, 217, 520 Annotation: Subtype: Link Rect: 56, 478, 109, 485 Annotation: Subtype: Link Rect: 159, 443, 212, 450 Annotation: Subtype: Link Rect: 79, 400, 132, 407 Annotation: Subtype: Link Rect: 246, 373, 286, 380 Annotation: Subtype: Link Rect: 56, 365, 70, 372 Annotation: Subtype: Link Rect: 159, 338, 217, 345 Annotation: Subtype: Link Rect: 222, 311, 286, 318 Annotation: Subtype: Link Rect: 123, 267, 194, 274 Annotation: Subtype: Link Rect: 76, 240, 166, 247 Annotation: Subtype: Link Rect: 56, 196, 135, 203 Annotation: Subtype: Link Rect: 153, 176, 202, 183 Annotation: Subtype: Link Rect: 217, 156, 283, 163 Annotation: Subtype: Link Rect: 56, 128, 128, 135 Annotation: Subtype: Link Rect: 148, 108, 220, 115 Annotation: Subtype: Link Rect: 441, 610, 494, 617 Annotation: Subtype: Link Rect: 436, 591, 489, 598 Annotation: Subtype: Link Rect: 382, 563, 469, 570 Annotation: Subtype: Link Rect: 493, 528, 538, 535 Annotation: Subtype: Link Rect: 309, 520, 326, 527 Annotation: Subtype: Link Rect: 425, 485, 523, 492 Annotation: Subtype: Link Rect: 497, 458, 538, 465 Annotation: Subtype: Link Rect: 309, 450, 357, 457 Annotation: Subtype: Link Rect: 364, 415, 441, 422 Annotation: Subtype: Link Rect: 428, 360, 513, 367 Annotation: Subtype: Link Rect: 428, 325, 493, 332 Annotation: Subtype: Link Rect: 461, 306, 514, 313 Annotation: Subtype: Link Rect: 451, 279, 536, 286 Annotation: Subtype: Link Rect: 309, 243, 362, 250 Annotation: Subtype: Link Rect: 397, 208, 478, 215 Annotation: Subtype: Link Rect: 437, 172, 508, 179 Annotation: Subtype: Link Rect: 479, 136, 537, 143 Annotation: Subtype: Link Rect: 460, 108, 522, 115 Annotation: Subtype: Link Rect: 443, 791, 538, 798 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 355, 662, 445, 669 Annotation: Subtype: Link Rect: 443, 791, 538, 798 Annotation: Subtype: Link Rect: 56, 39, 142, 46 Annotation: Subtype: Link Rect: 492, 39, 538, 46 Checksum: a5e9b6bd Type: CRC32 Checksum: 1c8dd316a6487cf9f6da3e96f68ca155 Type: MD5 Checksum: 9fd63f407391eb2eb033a835df49445e3163bc4a Type: SHA-1