adb68cafd338ebb1a12d971bb12388d2  pmc_9898037.pdf
a95f0e2c64dbc6c73da4712dba38f72c00eadea2  pmc_9898037.pdf
663d6cd672b76d89c5d5c524d616d47f2a6ce77d09f5d13a0eed0b956af52ff8  pmc_9898037.pdf

Title:          Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
Subject:        Leukemia, doi:10.1038/s41375-022-01802-y
Keywords:       
Author:         Larry Mansouri
Creator:        Springer
CreationDate:   Mon Jan 30 11:48:59 2023 CET
ModDate:        Mon Jan 30 11:51:33 2023 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           AcroForm
JavaScript:     no
Pages:          9
Encrypted:      no
Page size:      595.276 x 790.866 pts
Page rot:       0
File size:      1812417 bytes
Optimized:      yes
PDF version:    1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
DKCDNK+AdvTT5afe5d37.B               Type 1C           WinAnsi          yes yes no     691  0
DKCGOB+AdvOT46dcae81+20              Type 1C           WinAnsi          yes yes no     716  0
DKCGPB+AdvMyriad_I                   Type 1C           WinAnsi          yes yes no     717  0
DKCGPC+AdvMyriad_R                   Type 1C           WinAnsi          yes yes no     718  0
DKCGPD+AdvOT3b30f6db.B               Type 1C           WinAnsi          yes yes no     719  0
DKCGPE+AdvOTa20b42a7                 Type 1C           WinAnsi          yes yes no     732  0
DKCDPK+Arial-BoldMT                  Type 1C           WinAnsi          yes yes no     694  0
DKCEBL+AdvOTce3d9a73                 Type 1C           WinAnsi          yes yes no     702  0
DKCECL+AdvOT46dcae81                 Type 1C           WinAnsi          yes yes no     699  0
DKCECM+AdvTT6780a46b                 Type 1C           WinAnsi          yes yes no     700  0
DKCEPI+AdvTT6780a46b+fb              Type 1C           Custom           yes yes yes    705  0
DKCGNO+AdvTT2876772e+27              Type 1C           Custom           yes yes yes    725  0
DKCGNP+AdvOT65f8a23b.I               Type 1C           WinAnsi          yes yes no     726  0
DKCGOA+AdvOT46dcae81+fb              Type 1C           Custom           yes yes yes    712  0
DKCHBF+AdvTTab7e17fd                 Type 1C           WinAnsi          yes yes no     182  0
DKCHCF+AdvOT46dcae81+22              Type 1C           Custom           yes yes yes    180  0
DKCHCG+AdvOT919a0533.B               Type 1C           WinAnsi          yes yes no     184  0
DKCHCH+AdvOT7d2ebc01                 Type 1C           WinAnsi          yes yes no     176  0
DKCIAD+Arial-ItalicMT                Type 1C           WinAnsi          yes yes no     205  0
DKCIFC+ArialMT                       Type 1C           Custom           yes yes no     203  0
DKCIIC+AdvOT3b30f6db.B+fb            Type 1C           Custom           yes yes yes    240  0
DKCJAA+Arial-BoldItalicMT            Type 1C           WinAnsi          yes yes no     248  0
DKCKAL+AdvTT6780a46b+20              Type 1C           WinAnsi          yes yes no     253  0
DKCMBP+AdvOT3b30f6db.B+20            Type 1C           WinAnsi          yes yes no     291  0
DKCMDP+AdvOT8608a8d1+03              Type 1C           Custom           yes yes yes    292  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2023-07-07 02:39:06 CEST
 RepresentationInformation: pmc_9898037.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2023-02-09 02:14:53 CET
  Size: 1812417
  Format: PDF
  Version: 1.4
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR5' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR5' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR12' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR26' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR27' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR28' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR29' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR33' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR34' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR14' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR35' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR26' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR38' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR39' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR40' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR29' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR32' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR44' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR45' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR46' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR47' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR44' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR48' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR49' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR50' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR31' cannot be found
   Offset: 1781291
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR51' cannot be found
   Offset: 1781291
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 890
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermu琀愀琀椀漀渀 猀琀愀琀甀猀㨀 愀 猀琀甀搀礀 戀礀 䔀刀䤀䌀 椀渀 䠀䄀刀䴀伀一天㸾൥湤潢樍㠷ㄠ〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀ㄩ⽆‰⽎數琠㠸㌠〠刯偡牥湴‸㜰‰⁒⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㠷㈠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䴀ㄩ⽆‰⽐慲敮琠㠷〠〠刯偲敶‸㜳‰⁒⽔楴汥⣾＀䄀䐀䐀䤀吀䤀伀一䄀䰀 䤀一䘀伀刀䴀䄀吀䤀伀丩㸾൥湤潢樍㠷㌠〠潢樍㰼⽃嬰⸰‰⸰‰⸰崯䍯畮琠〯䑥獴⣾＀䄀㤩⽆‰⽎數琠㠷㈠〠刯偡牥湴‸㜰‰⁒⽐牥瘠㠷㐠〠刯呩瑬攨Competing interests
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6
      Children: 
       Item: 
        Title: Introduction
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f
       Item: 
        Title: Materials and methods
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003
        Children: 
         Item: 
          Title: Patients
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191
         Item: 
          Title: Mutational analysis
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb
         Item: 
          Title: Statistical analysis
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6
        Children: 
         Item: 
          Title: Frequency of recurrent gene mutations
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a
         Item: 
          Title: Clinicobiological profiles associated with recurrent gene mutations
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71
         Item: 
          Title: Recurrent gene mutations and clinical outcome
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2
         Item: 
          Title: Multivariate analysis reveals different impact of molecular markers in U-CLL and M-CLL
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9
       Item: 
        Title: Discussion
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f
       Item: 
        Title: References
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78
       Item: 
        Title: Acknowledgements
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee
       Item: 
        Title: ACKNOWLEDGMENTS
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f
       Item: 
        Title: Author contributions
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1
       Item: 
        Title: Funding
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d
       Item: 
        Title: Competing interests
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89
       Item: 
        Title: ADDITIONAL INFORMATION
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9
   Info: 
    Title: Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
    Author: Larry Mansouri
    Subject: Leukemia, doi:10.1038/s41375-022-01802-y
    Keywords: 
    Creator: Springer
    CreationDate: Mon Jan 30 12:18:59 CET 2023
    ModDate: Mon Jan 30 12:21:33 CET 2023
   ID: 0x690017a89aa6cf839478d5f9a00078c5, 0xd2b6d5a9152334409555459b81d7ac3e
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 994
      ImageHeight: 635
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 549
      ImageHeight: 440
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: DKCEPI+AdvTT6780a46b+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: DKCEPI+AdvTT6780a46b+fb
       Flags: Symbolic
       FontBBox: 9, 0, 875, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DKCGOA+AdvOT46dcae81+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: DKCGOA+AdvOT46dcae81+fb
       Flags: Symbolic
       FontBBox: 0, 0, 739, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DKCIFC+ArialMT
      FontSubset: true
      FirstChar: 21
      LastChar: 122
      FontDescriptor: 
       FontName: DKCIFC+ArialMT
       Flags: Nonsymbolic
       FontBBox: -665, -325, 2000, 1040
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: DKCGOB+AdvOT46dcae81+20
      FontSubset: true
      FirstChar: 146
      LastChar: 151
      FontDescriptor: 
       FontName: DKCGOB+AdvOT46dcae81+20
       Flags: Nonsymbolic
       FontBBox: 0, -197, 1125, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCGPB+AdvMyriad_I
      FontSubset: true
      FirstChar: 76
      LastChar: 117
      FontDescriptor: 
       FontName: DKCGPB+AdvMyriad_I
       Flags: Nonsymbolic
       FontBBox: -104, -239, 1083, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCIAD+Arial-ItalicMT
      FontSubset: true
      FirstChar: 32
      LastChar: 119
      FontDescriptor: 
       FontName: DKCIAD+Arial-ItalicMT
       Flags: Nonsymbolic, Italic
       FontBBox: -517, -325, 1359, 998
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCGPC+AdvMyriad_R
      FontSubset: true
      FirstChar: 40
      LastChar: 150
      FontDescriptor: 
       FontName: DKCGPC+AdvMyriad_R
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCGPD+AdvOT3b30f6db.B
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: DKCGPD+AdvOT3b30f6db.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCGNO+AdvTT2876772e+27
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: DKCGNO+AdvTT2876772e+27
       Flags: Symbolic
       FontBBox: 0, -197, 968, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DKCGNP+AdvOT65f8a23b.I
      FontSubset: true
      FirstChar: 44
      LastChar: 112
      FontDescriptor: 
       FontName: DKCGNP+AdvOT65f8a23b.I
       Flags: Nonsymbolic
       FontBBox: -104, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCGPE+AdvOTa20b42a7
      FontSubset: true
      FirstChar: 48
      LastChar: 118
      FontDescriptor: 
       FontName: DKCGPE+AdvOTa20b42a7
       Flags: Serif, Nonsymbolic
       FontBBox: -72, -239, 979, 906
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCMBP+AdvOT3b30f6db.B+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: DKCMBP+AdvOT3b30f6db.B+20
       Flags: Nonsymbolic
       FontBBox: -10, -197, 1250, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCMDP+AdvOT8608a8d1+03
      FontSubset: true
      FirstChar: 0
      LastChar: 0
      FontDescriptor: 
       FontName: DKCMDP+AdvOT8608a8d1+03
       Flags: Symbolic
       FontBBox: -479, -364, 854, 927
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DKCHCH+AdvOT7d2ebc01
      FontSubset: true
      FirstChar: 48
      LastChar: 55
      FontDescriptor: 
       FontName: DKCHCH+AdvOT7d2ebc01
       Flags: Nonsymbolic
       FontBBox: -31, -208, 958, 916
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCIIC+AdvOT3b30f6db.B+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: DKCIIC+AdvOT3b30f6db.B+fb
       Flags: Symbolic
       FontBBox: 0, 0, 833, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DKCDNK+AdvTT5afe5d37.B
      FontSubset: true
      FirstChar: 65
      LastChar: 84
      FontDescriptor: 
       FontName: DKCDNK+AdvTT5afe5d37.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 895, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCHCF+AdvOT46dcae81+22
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: DKCHCF+AdvOT46dcae81+22
       Flags: Symbolic
       FontBBox: 0, -145, 687, 822
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DKCDPK+Arial-BoldMT
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: DKCDPK+Arial-BoldMT
       Flags: Nonsymbolic
       FontBBox: -628, -376, 2000, 1010
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCHBF+AdvTTab7e17fd
      FontSubset: true
      FirstChar: 43
      LastChar: 61
      FontDescriptor: 
       FontName: DKCHBF+AdvTTab7e17fd
       Flags: Nonsymbolic
       FontBBox: -156, -250, 1072, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCHCG+AdvOT919a0533.B
      FontSubset: true
      FirstChar: 46
      LastChar: 108
      FontDescriptor: 
       FontName: DKCHCG+AdvOT919a0533.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 656, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCJAA+Arial-BoldItalicMT
      FontSubset: true
      FirstChar: 49
      LastChar: 89
      FontDescriptor: 
       FontName: DKCJAA+Arial-BoldItalicMT
       Flags: Nonsymbolic, Italic
       FontBBox: -560, -376, 1390, 1018
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCECL+AdvOT46dcae81
      FontSubset: true
      FirstChar: 35
      LastChar: 246
      FontDescriptor: 
       FontName: DKCECL+AdvOT46dcae81
       Flags: Nonsymbolic
       FontBBox: -41, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCECM+AdvTT6780a46b
      FontSubset: true
      FirstChar: 37
      LastChar: 252
      FontDescriptor: 
       FontName: DKCECM+AdvTT6780a46b
       Flags: Nonsymbolic
       FontBBox: -41, -250, 875, 843
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCKAL+AdvTT6780a46b+20
      FontSubset: true
      FirstChar: 146
      LastChar: 151
      FontDescriptor: 
       FontName: DKCKAL+AdvTT6780a46b+20
       Flags: Nonsymbolic
       FontBBox: 0, -114, 1156, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DKCEBL+AdvOTce3d9a73
      FontSubset: true
      FirstChar: 65
      LastChar: 89
      FontDescriptor: 
       FontName: DKCEBL+AdvOTce3d9a73
       Flags: Nonsymbolic
       FontBBox: -41, -250, 854, 885
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.2-c001 63.143651, 2012/04/05-09:01:49        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1038/s41375-022-01802-y</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Larry Mansouri</rdf:li>
               <rdf:li>Birna Thorvaldsdottir</rdf:li>
               <rdf:li>Lesley-Ann Sutton</rdf:li>
               <rdf:li>Georgios Karakatsoulis</rdf:li>
               <rdf:li>Manja Meggendorfer</rdf:li>
               <rdf:li>Helen Parker</rdf:li>
               <rdf:li>Ferran Nadeu</rdf:li>
               <rdf:li>Christian Brieghel</rdf:li>
               <rdf:li>Stamatia Laidou</rdf:li>
               <rdf:li>Riccardo Moia</rdf:li>
               <rdf:li>Davide Rossi</rdf:li>
               <rdf:li>Mark Catherwood</rdf:li>
               <rdf:li>Jana Kotaskova</rdf:li>
               <rdf:li>Julio Delgado</rdf:li>
               <rdf:li>Ana E. Rodríguez-Vicente</rdf:li>
               <rdf:li>Rocío Benito</rdf:li>
               <rdf:li>Gian Matteo Rigolin</rdf:li>
               <rdf:li>Silvia Bonfiglio</rdf:li>
               <rdf:li>Lydia Scarfo</rdf:li>
               <rdf:li>Mattias Mattsson</rdf:li>
               <rdf:li>Zadie Davis</rdf:li>
               <rdf:li>Ajay Gogia</rdf:li>
               <rdf:li>Lata Rani</rdf:li>
               <rdf:li>Panagiotis Baliakas</rdf:li>
               <rdf:li>Hassan Foroughi-Asl</rdf:li>
               <rdf:li>Cecilia Jylhä</rdf:li>
               <rdf:li>Aron Skaftason</rdf:li>
               <rdf:li>Inmaculada Rapado</rdf:li>
               <rdf:li>Fatima Miras</rdf:li>
               <rdf:li>Joaquín Martinez-Lopez</rdf:li>
               <rdf:li>Javier Serna</rdf:li>
               <rdf:li>Jesús María Hernández Rivas</rdf:li>
               <rdf:li>Patrick Thornton</rdf:li>
               <rdf:li>María José Larráyoz</rdf:li>
               <rdf:li>María José Calasanz</rdf:li>
               <rdf:li>Viktória Fésüs</rdf:li>
               <rdf:li>Zoltán Mátrai</rdf:li>
               <rdf:li>Csaba Bödör</rdf:li>
               <rdf:li>Karin E. Smedby</rdf:li>
               <rdf:li>Blanca Espinet</rdf:li>
               <rdf:li>Anna Puiggros</rdf:li>
               <rdf:li>Ritu Gupta</rdf:li>
               <rdf:li>Lars Bullinger</rdf:li>
               <rdf:li>Francesc Bosch</rdf:li>
               <rdf:li>Bárbara Tazón-Vega</rdf:li>
               <rdf:li>Fanny Baran-Marszak</rdf:li>
               <rdf:li>David Oscier</rdf:li>
               <rdf:li>Florence Nguyen-Khac</rdf:li>
               <rdf:li>Thorsten Zenz</rdf:li>
               <rdf:li>Maria Jose Terol</rdf:li>
               <rdf:li>Antonio Cuneo</rdf:li>
               <rdf:li>María Hernández-Sánchez</rdf:li>
               <rdf:li>Sarka Pospisilova</rdf:li>
               <rdf:li>Ken Mills</rdf:li>
               <rdf:li>Gianluca Gaidano</rdf:li>
               <rdf:li>Carsten U. Niemann</rdf:li>
               <rdf:li>Elias Campo</rdf:li>
               <rdf:li>Jonathan C. Strefford</rdf:li>
               <rdf:li>Paolo Ghia</rdf:li>
               <rdf:li>Kostas Stamatopoulos</rdf:li>
               <rdf:li>Richard Rosenquist</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Springer US</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:subject>
            <rdf:Bag/>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Leukemia, doi:10.1038/s41375-022-01802-y</rdf:li>
            </rdf:Alt>
         </dc:description>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2023-01-30T16:21:33+05:30</xmp:ModifyDate>
         <xmp:CreateDate>2023-01-30T16:18:59+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2023-01-30T16:21:33+05:30</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords/>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#">
         <xmpMM:DocumentID>uuid:94d88c37-8241-43f4-b61b-e983f4d09c32</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:63218dee-2b38-49c2-8bcc-a80230f3f087</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:45cc2d32-517e-4451-8571-893a3bb2a61a</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2023-01-30T16:21:33+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/">
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
            xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
            xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#">
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 339
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 478, 689, 480, 721
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 478, 695, 534, 727
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 534, 695, 549, 705
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 534, 695, 549, 705
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 191, 576, 192, 585
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 191, 576, 192, 585
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 201, 576, 203, 585
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 194, 576, 201, 585
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 201, 576, 201, 585
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 88, 565, 89, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 88, 565, 89, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 98, 565, 100, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 91, 565, 98, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 98, 565, 98, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 180, 565, 181, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 180, 565, 181, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 190, 565, 192, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 183, 565, 190, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 190, 565, 190, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 261, 565, 262, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 261, 565, 262, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 271, 565, 274, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 264, 565, 271, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 271, 565, 272, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 335, 565, 336, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 335, 565, 336, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 345, 565, 347, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 337, 565, 345, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 345, 565, 345, 574
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 95, 555, 96, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 95, 555, 96, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 105, 555, 107, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 97, 555, 105, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 105, 555, 105, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 315, 555, 316, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 315, 555, 316, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 325, 555, 328, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 318, 555, 325, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 325, 555, 325, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 403, 555, 404, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 403, 555, 404, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 413, 555, 416, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 406, 555, 413, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 413, 555, 414, 563
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 287, 544, 288, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 287, 544, 288, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 297, 544, 299, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 289, 544, 297, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 297, 544, 297, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 484, 544, 485, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 484, 544, 485, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 494, 544, 496, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 486, 544, 494, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 494, 544, 494, 552
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 115, 533, 116, 542
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 115, 533, 116, 542
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 124, 533, 127, 542
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 117, 533, 124, 542
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 124, 533, 125, 542
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 104, 522, 105, 531
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 104, 522, 105, 531
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 114, 522, 117, 531
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 107, 522, 114, 531
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 114, 522, 114, 531
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 214, 511, 215, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 214, 511, 215, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 224, 511, 226, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 217, 511, 224, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 224, 511, 224, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 368, 511, 369, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 368, 511, 369, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 378, 511, 380, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 371, 511, 378, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 378, 511, 378, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 501, 511, 502, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 501, 511, 502, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 511, 511, 513, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 504, 511, 511, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 511, 511, 511, 520
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 341, 500, 342, 509
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 341, 500, 342, 509
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 351, 500, 353, 509
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 343, 500, 351, 509
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 351, 500, 351, 509
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 91, 489, 92, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 91, 489, 92, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 101, 489, 104, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 94, 489, 101, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 101, 489, 101, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 360, 489, 361, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 360, 489, 361, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 370, 489, 372, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 362, 489, 370, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 370, 489, 370, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 529, 489, 530, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 529, 489, 530, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 539, 489, 541, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 531, 489, 539, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 539, 489, 539, 498
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 190, 478, 191, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 190, 478, 191, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 200, 478, 203, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 193, 478, 200, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 200, 478, 201, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 256, 478, 258, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 256, 478, 258, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 266, 478, 269, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 259, 478, 266, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 266, 478, 267, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 379, 478, 380, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 379, 478, 380, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 389, 478, 392, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 382, 478, 389, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 389, 478, 389, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 440, 478, 441, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 440, 478, 441, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 450, 478, 452, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 442, 478, 450, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 450, 478, 450, 487
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 121, 467, 122, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 121, 467, 122, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 131, 467, 134, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 124, 467, 131, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 131, 467, 131, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 243, 467, 244, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 243, 467, 244, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 253, 467, 256, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 246, 467, 253, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 253, 467, 254, 476
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 159, 269, 324, 278
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 166, 158, 170, 167
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 177, 158, 182, 167
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 138, 128, 142, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 304, 218, 308, 227
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 315, 218, 319, 227
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 518, 188, 522, 197
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 527, 188, 531, 197
       Flags: Print
       AppearanceDictionary: true
       Destination: 142
      Annotation: 
       Subtype: Link
       Rect: 513, 148, 518, 157
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 522, 148, 532, 157
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 536, 148, 545, 157
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 508, 108, 517, 117
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 522, 108, 531, 117
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 476, 749, 549, 757
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 340
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 47, 336, 56, 345
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 62, 336, 72, 345
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 197, 306, 206, 315
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 210, 306, 219, 315
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 47, 276, 56, 285
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 64, 276, 73, 285
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 80, 276, 90, 285
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 97, 276, 106, 285
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 47, 226, 56, 235
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 61, 226, 70, 235
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 166, 186, 175, 195
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 180, 186, 189, 195
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 385, 292, 393, 300
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 424, 274, 428, 282
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 385, 265, 389, 273
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 181, 395, 185, 403
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
     Thumb: true
    Page: 
     Label: 341
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 276, 189, 280, 197
       Flags: Print
       AppearanceDictionary: true
       Destination: 142
      Annotation: 
       Subtype: Link
       Rect: 130, 153, 134, 161
       Flags: Print
       AppearanceDictionary: true
       Destination: 119
      Annotation: 
       Subtype: Link
       Rect: 399, 180, 407, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 427, 118, 431, 127
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 492, 78, 497, 87
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
     Thumb: true
    Page: 
     Label: 342
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 63, 693, 68, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 142, 633, 147, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 89, 583, 98, 592
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 105, 583, 114, 592
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 106, 524, 111, 533
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 47, 434, 56, 443
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 62, 434, 71, 443
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 77, 434, 86, 443
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 92, 434, 101, 443
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 105, 434, 114, 443
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 227, 394, 232, 403
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 204, 374, 208, 383
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 136, 294, 141, 303
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 255, 205, 260, 214
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 182, 145, 191, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 404, 703, 409, 712
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 410, 633, 415, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 436, 554, 440, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 358, 494, 362, 503
       Flags: Print
       AppearanceDictionary: true
       Destination: 24
      Annotation: 
       Subtype: Link
       Rect: 526, 424, 535, 433
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 489, 105, 494, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 71
      Annotation: 
       Subtype: Link
       Rect: 450, 75, 454, 84
       Flags: Print
       AppearanceDictionary: true
       Destination: 71
      Annotation: 
       Subtype: Link
       Rect: 510, 55, 515, 64
       Flags: Print
       AppearanceDictionary: true
       Destination: 71
     Thumb: true
    Page: 
     Label: 343
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 265, 241, 269, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 54, 191, 59, 200
       Flags: Print
       AppearanceDictionary: true
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 91, 141, 95, 150
       Flags: Print
       AppearanceDictionary: true
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 143, 111, 148, 120
       Flags: Print
       AppearanceDictionary: true
       Destination: 87
      Annotation: 
       Subtype: Link
       Rect: 346, 121, 351, 130
       Flags: Print
       AppearanceDictionary: true
       Destination: 87
     Thumb: true
    Page: 
     Label: 344
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 313, 268, 322, 277
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 328, 268, 337, 277
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 342, 268, 351, 277
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 482, 248, 491, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 495, 248, 504, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 508, 248, 517, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 520, 248, 529, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 533, 248, 542, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 546, 248, 555, 257
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 393, 168, 402, 177
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 313, 128, 322, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 328, 128, 337, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 342, 128, 351, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 514, 118, 523, 127
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 530, 118, 539, 127
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 545, 118, 555, 127
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 345
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 212, 623, 221, 632
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 227, 623, 237, 632
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 243, 623, 252, 632
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 256, 623, 266, 632
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 118, 593, 128, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 135, 593, 145, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 153, 593, 162, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 170, 593, 179, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 164, 554, 173, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 217, 314, 226, 323
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 231, 314, 241, 323
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 246, 314, 255, 323
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 152, 284, 162, 293
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 165, 284, 175, 293
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 125, 225, 134, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 61, 55, 71, 64
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 346
     Sequence: 8
     Thumb: true
    Page: 
     Label: 347
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 337, 559, 465, 566
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 457, 523, 548, 530
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 531, 371, 549, 378
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 301, 362, 412, 369
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 298, 90, 370, 97
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: ae3dbc68
   Type: CRC32
  Checksum: adb68cafd338ebb1a12d971bb12388d2
   Type: MD5
  Checksum: a95f0e2c64dbc6c73da4712dba38f72c00eadea2
   Type: SHA-1