83aa00d5d0fc369a8dbe134ae13f6861 pmc_9907557.pdf aff3011774db55adda4f811b083f4acdd75a9973 pmc_9907557.pdf fc1fe42dd9342a9ab7191e6665709a71c83463d3b6b9a54ae3db6b3bdc78a133 pmc_9907557.pdf Title: Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference Subject: DOI: 10.1093/europace/euac062; Europace, 25, 1, 2022-07-27.; Abstract: Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three international experts met in Hamburg for 2 days in October 2021. Results of the interdisciplinary, hybrid discussions in breakout groups and the plenary based on recently published and unpublished observations are summarized in this consensus paper to support improved care for patients with AF by guiding prevention, individualized management, and research strategies. The main outcomes are (i) new evidence supports a simple, scalable, and pragmatic population-based AF screening pathway; (ii) rhythm management is evolving from therapy aimed at improving symptoms to an integrated domain in the prevention of AF-related outcomes, especially in patients with recently diagnosed AF; (iii) improved characterization of atrial cardiomyopathy may help to identify patients in need for therapy; (iv) standardized assessment of cognitive function in patients with AF could lead to improvement in patient outcomes; and (v) artificial intelligence (AI) can support all of the above aims, but requires advanced interdisciplinary knowledge and collaboration as well as a better medico-legal framework. Implementation of new evidence-based approaches to AF screening and rhythm management can improve outcomes in patients with AF. Additional benefits are possible with further efforts to identify and target atrial cardiomyopathy and cognitive impairment, which can be facilitated by AI. Keywords: Atrial fibrillation; Artificial intelligence; Heart failure; Atrial cardiomyopathy; Cognitive function; Dementia; Outcomes; Quality of care; Cost; Research; Rhythm management; Catheter ablation; Anticoagulation; Bleeding; Research priorities; Technology; Stroke; Integrated care; Screening; AFNET; EHRA; Guidelines; Consensus statement Author: Renate B. 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Approaches to screening Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Evidence-based implementation of systematic screening for atrial fibrillation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Consumer-led atrial fibrillation screening Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Knowledge gaps and hurdles Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: The growing role of rhythm management Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Children: Item: Title: The paradigm of rhythm management Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Attempt at restoration of sinus rhythm Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Lifelong rhythm management Destination: 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Knowledge gaps and research opportunities Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Atrial (cardio)myopathies: definition, risk factors, and progression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Children: Item: Title: Defining the concept Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Item: Title: Atrial cardiomyopathy disease progression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20 Item: Title: Atrial cardiomyopathy and atrial fibrillation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743 Item: Title: Potential practical implications Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858 Item: Title: Knowledge gaps and research opportunities Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71 Item: Title: Structuring high-quality care Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3 Children: Item: Title: Practical implications Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@32eebfca Item: Title: Knowledge gaps and research opportunities Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207 Item: Title: Artificial intelligence in the management of atrial fibrillation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d Children: Item: Title: Knowledge gaps and research opportunities Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@543c6f6d Item: Title: Steps to facilitate clinical implementation of artificial intelligence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13eb8acf Item: Title: Summary Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@51c8530f Item: Title: Supplementary material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7403c468 Item: Title: 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950 FontFile2: true XMP: uuid:6879b881-a6fa-4ae7-af72-027cac24a662 uuid:9C6FA13D-679E-02A2-0D07-E5D2655906C1 True Atrial fibrillation; Artificial intelligence; Heart failure; Atrial cardiomyopathy; Cognitive function; Dementia; Outcomes; Quality of care; Cost; Research; Rhythm management; Catheter ablation; Anticoagulation; Bleeding; Research priorities; Technology; Stroke; Integrated care; Screening; AFNET; EHRA; Guidelines; Consensus statement PDFlib+PDI 9.0.7p3 (C++/Win64) application/pdf 10.1093/europace/euac062 en Oxford University Press Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference Renate B. Schnabel Elena Andreassi Marinelli Elena Arbelo Giuseppe Boriani Serge Boveda Claire M. Buckley A. John Camm Barbara Casadei Winnie Chua Nikolaos Dagres Mirko de Melis Lien Desteghe Søren Zöga Diederichsen David Duncker Lars Eckardt Christoph Eisert Daniel Engler Larissa Fabritz Ben Freedman Ludovic Gillet Andreas Goette Eduard Guasch Jesper Hastrup Svendsen Stéphane N. Hatem Karl Georg Haeusler Jeff S. Healey Hein Heidbuchel Gerhard Hindricks F.D. Richard Hobbs Thomas Hübner Dipak Kotecha Michael Krekler Christophe Leclercq Thorsten Lewalter Honghuang Lin Dominik Linz Gregory Y.H. Lip Maja-Lisa Løchen Wim Lucassen Katarzyna Malaczynska-Rajpold Steffen Massberg Jose L. Merino Ralf Meyer Lluıs Mont Michael C. Myers Lis Neubeck Teemu Niiranen Michael Oeff Jonas Oldgren Tatjana S. Potpara George Psaroudakis Helmut Pürerfellner Ursula Ravens Michiel Rienstra Lena Rivard Daniel Scherr Ulrich Schotten Dipen Shah Moritz F. Sinner Rüdiger Smolnik Gerhard Steinbeck Daniel Steven Emma Svennberg Dierk Thomas Mellanie True Hills Isabelle C. van Gelder Burcu Vardar Elena Palà Reza Wakili Karl Wegscheider Mattias Wieloch Stephan Willems Henning Witt André Ziegler Matthias Daniel Zink Paulus Kirchhof DOI: 10.1093/europace/euac062; Europace, 25, 1, 2022-07-27.; Abstract: Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three international experts met in Hamburg for 2 days in October 2021. Results of the interdisciplinary, hybrid discussions in breakout groups and the plenary based on recently published and unpublished observations are summarized in this consensus paper to support improved care for patients with AF by guiding prevention, individualized management, and research strategies. The main outcomes are (i) new evidence supports a simple, scalable, and pragmatic population-based AF screening pathway; (ii) rhythm management is evolving from therapy aimed at improving symptoms to an integrated domain in the prevention of AF-related outcomes, especially in patients with recently diagnosed AF; (iii) improved characterization of atrial cardiomyopathy may help to identify patients in need for therapy; (iv) standardized assessment of cognitive function in patients with AF could lead to improvement in patient outcomes; and (v) artificial intelligence (AI) can support all of the above aims, but requires advanced interdisciplinary knowledge and collaboration as well as a better medico-legal framework. Implementation of new evidence-based approaches to AF screening and rhythm management can improve outcomes in patients with AF. Additional benefits are possible with further efforts to identify and target atrial cardiomyopathy and cognitive impairment, which can be facilitated by AI. © The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Cardiology. Atrial fibrillation Artificial intelligence Heart failure Atrial cardiomyopathy Cognitive function Dementia Outcomes Quality of care Cost Research Rhythm management Catheter ablation Anticoagulation Bleeding Research priorities Technology Stroke Integrated care Screening AFNET EHRA Guidelines Consensus statement Journal Europace © The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Cardiology. 1099-5129 1532-2092 25 1 6 27 10.1093/europace/euac062 https://doi.org/10.1093/europace/euac062 2023-02-03T12:39:56+05:30 2023-02-06T10:29:07+05:30 Servigistics Arbortext Advanced Print Publisher 11.1.4546/W-x64 2023-02-06T10:29:07+05:30 PStill version 1.84.42 1 PDF/UA Universal Accessibility Schema http://www.aiim.org/pdfua/ns/id/ pdfuaid part Integer internal Indicates, which part of ISO 14289 standard is followed Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 164, 553, 174, 563 Flags: Print Annotation: Subtype: Link Rect: 486, 377, 496, 387 Flags: Print Annotation: Subtype: Link Rect: 299, 88, 351, 95 Flags: Print Annotation: Subtype: Link Rect: 385, 70, 516, 77 Flags: Print Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 343, 116, 347, 125 Flags: Print Destination: 67 Annotation: Subtype: Link Rect: 348, 116, 352, 125 Flags: Print Destination: 67 Page: Sequence: 3 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