1e430b9788e73ca55dcf4758dfea41b1 BioPha_a2023v164p114796iENG.pdf 28cade74bf1e736d326ef5b806788a1d440c2514 BioPha_a2023v164p114796iENG.pdf 12e6bd0c00fa440aaef18676857523b4eb97bb37ab4aaf335d8feaac94888be7 BioPha_a2023v164p114796iENG.pdf Title: Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles Subject: Biomedicine & Pharmacotherapy, 164 (2023) 114976. doi:10.1016/j.biopha.2023.114976 Keywords: Recombinant proteins,Biomaterials,Nanoparticles,Pyroptosis,Cancer,Drug delivery,Gasdermin D Author: Carlos Martínez-Torró Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Fri Jun 16 07:00:34 2023 CEST ModDate: Fri Jun 16 08:06:45 2023 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 10471186 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KEPREY+TeX_CM_Maths_Symbols Type 1C Builtin yes yes yes 1336 0 KBKWAG+CharisSIL CID TrueType Identity-H yes yes yes 1340 0 ZCGAUS+STIX-Regular Type 1C Custom yes yes yes 1345 0 VXCJFZ+Univers Type 1C Builtin yes yes yes 1350 0 IEQCQA+CharisSIL-Bold CID TrueType Identity-H yes yes yes 1354 0 CDQGFZ+STIX-Italic Type 1C Custom yes yes yes 1359 0 OYUUBL+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 1364 0 NNLAUQ+TeX_CM_Roman Type 1C Builtin yes yes yes 1369 0 TQPJSA+CharisSIL-Italic CID TrueType Identity-H yes yes yes 1373 0 OCCNXH+CharisSIL CID TrueType Identity-H yes yes yes 1327 0 XELSLR+CharisSIL-Italic CID TrueType Identity-H yes yes yes 613 0 SSHIIE+TeX_CM_Maths_Italic Type 1C Builtin yes yes yes 132 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-06-30 02:35:50 CEST RepresentationInformation: BioPha_a2023v164p114796iENG.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-06-29 13:33:16 CEST Size: 10471186 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 1458 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, p ... Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Children: Item: Title: 1 Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: 2 Materials and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Children: Item: Title: 2.1 Protein design, production and purification Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: 2.2 Dynamic light scattering Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 2.3 Protein stability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: 2.4 Cell culture and in vitro cell viability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: 2.5 Animal procedures and histology Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: 2.6 Cell cytometry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: 3 Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 4 Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: 5 Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: CRediT authorship contribution statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: Declaration of Competing Interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Data Availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Info: Title: Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles Author: Carlos Martínez-Torró Subject: Biomedicine & Pharmacotherapy, 164 (2023) 114976. doi:10.1016/j.biopha.2023.114976 Keywords: Recombinant proteins,Biomaterials,Nanoparticles,Pyroptosis,Cancer,Drug delivery,Gasdermin D Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Fri Jun 16 07:00:34 CEST 2023 ModDate: Fri Jun 16 08:06:45 CEST 2023 ID: 0x58219958e6169dede8350aa37cfee694, 0x08e7733066a2ed9c6b1e9a17b1395a20 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: OYUUBL+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Font: 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Carrasco-Díaz Naroa Serna Laura Imedio Alberto Gallardo Isolda Casanova Ugutz Unzueta Esther Vázquez Ramón Mangues Antonio Villaverde journal Biomedicine & Pharmacotherapy © 2023 The Author(s). 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