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Title:          Design strategies for positively charged endolysins: Insights into Artilysin development
Subject:        Biotechnology Advances, 69 (2023) 108250. doi:10.1016/j.biotechadv.2023.108250
Keywords:       Endolysins,Antibacterial agents,Gram-negative bacteria,Outer membrane,Cationic peptides,Artilysins,Protein engineering
Author:         Jose Vicente Carratalá
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      Title: Design strategies for positively charged endolysins: Insights into Artilysin development
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        Title: 1 Introduction
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          Title: 1.1 Endolysins
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          Title: 1.2 Architecture of endolysins
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          Title: 1.3 Endolysin cleavage site specificity
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        Title: 2 Influence of endolysin's charged regions on gram-negative antimicrobial potential
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        Title: 3 De novo design
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          Title: 3.1 Increasing the net charge of endolysins
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          Title: 3.2 Exploiting the potential of endolysin engineering
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           Item: 
            Title: 3.2.1 Optimizing Artilysin design: To N-terminal modify, or C-terminal modify? That is the Artilysin design question
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            Title: 3.2.3 Optimizing Artilysin design: Cationic and hydrophobic amino acids in peptide composition
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          Title: 3.3 Alternative design options
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        Title: Declaration of Competing Interest
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        Title: References
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  Checksum: c1418e72
   Type: CRC32
  Checksum: 9813f6341e06afd153cb5add17a91552
   Type: MD5
  Checksum: 2e96e13ad368e1b80f69fca9e800ae42c19b6c3d
   Type: SHA-1