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Destination: slink2 Item: Title: Bulk RNA sequencing and analysis Destination: slink3 Item: Title: Single-cell RNA sequencing (scRNA-seq) and analysis Destination: slink4 Item: Title: WES and analysis Destination: slink5 Item: Title: Immunohistochemical staining Destination: slink6 Item: Title: T-cell immunophenotyping Destination: slink7 Item: Title: Quantification and statistical analysis Destination: slink8 Item: Title: Results Destination: flink3 Children: Item: Title: Microenvironmental modulation of tumor cells Destination: slink9 Item: Title: Intratumoral transcriptional heterogeneity within the TME Destination: slink10 Item: Title: Interaction between immune cells of the TME and activated CLL Destination: slink11 Item: Title: Permissive TME promotes the expansion of genetic subclones Destination: slink12 Item: Title: Discussion Destination: flink4 Item: Title: Authorship Destination: flink5 Item: Title: References Destination: blink1 Info: Title: The immune microenvironment 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FontDescriptor: FontName: EMAKDK+AdvOT333dc5e5 Flags: Nonsymbolic FontBBox: -31, -250, 1010, 937 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMAKEP+AdvTT51434264+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: EMAKEP+AdvTT51434264+20 Flags: Nonsymbolic FontBBox: -177, -197, 1239, 750 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1182/bloodadvances.2021006941 The immune microenvironment shapes transcriptional and genetic heterogeneity in chronic lymphocytic leukemia Clare Sun Yun-Ching Chen Aina Martinez Zurita Maria Joao Baptista Stefania Pittaluga Delong Liu Daniel Rosebrock Satyen Harish Gohil Nakhle S. Saba Theresa Davies-Hill Sarah E.M. Herman Gad Getz Mehdi Pirooznia Catherine J. Wu Adrian Wiestner BLOOD ADVANCES, 7 (2023) 145-158. doi:10.1182/bloodadvances.2021006941 The American Society of Hematology journal BLOOD ADVANCES © 2022 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. 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