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Variational Autoencoders (VAEs) Destination: mk:H2_4 Item: Title: 2.5 Generative Adversarial Networks (GANs) Destination: mk:H2_5 Item: Title: 3 Essential concepts in single-cell omics Destination: mk:H1_3 Children: Item: Title: 3.1 Transcriptomics Destination: mk:H2_6 Item: Title: 3.2 Genomics Destination: mk:H2_7 Item: Title: 3.3 Epigenomics Destination: mk:H2_8 Item: Title: 4 Deep Learning applications in single-cell omics Destination: mk:H1_4 Children: Item: Title: 4.1 Deep learning in single-cell transcriptomics Destination: mk:H2_9 Children: Item: Title: 4.1.1 Pre-processing and quality control Destination: mk:H3_10 Item: Title: 4.1.2 Normalization Destination: mk:H3_11 Item: Title: 4.1.3 Data correction Destination: mk:H3_12 Children: Item: Title: 4.1.3.1 Dropout Destination: mk:H4_13 Item: Title: 4.1.3.2 Batch effects correction Destination: mk:H4_14 Item: Title: 4.1.3.3 Dimensionality reduction Destination: mk:H4_15 Item: Title: 4.1.3.4 In-silico generation and augmentation Destination: mk:H4_16 Item: Title: 4.1.4 Downstream analysis Destination: mk:H3_17 Children: Item: Title: 4.1.4.1 Clustering and cell annotation Destination: mk:H4_18 Item: Title: 4.1.4.2 Cell-Cell communication analysis Destination: mk:H4_19 Item: Title: 4.1.4.3 RNA velocity Destination: mk:H4_20 Item: Title: 4.2 Deep learning in single-cell genomics Destination: mk:H2_21 Children: Item: Title: 4.2.1 Cell type identification in CyTOF Destination: mk:H3_22 Item: Title: 4.2.2 DNA methylation Destination: mk:H3_23 Item: Title: 4.2.3 Histone modification Destination: mk:H3_24 Item: Title: 4.2.4 CNV and SNP prediction Destination: mk:H3_25 Item: Title: 4.3 Deep learning in spatial transcriptomics Destination: mk:H2_26 Item: Title: 4.4 Integrating scRNA-seq and spatial transcriptomics (spot deconvolution) Destination: mk:H2_27 Item: Title: 4.5 Deep learning in the integration of single-cell multimodal omics data Destination: mk:H2_28 Item: Title: 5 Conclusions and future perspective Destination: mk:H1_5 Item: Title: Declarations Destination: mk:H1_6 Children: Item: Title: Ethics approval and consent to participate Destination: mk:H2_29 Item: Title: Funding Statement Destination: mk:H2_30 Item: Title: CRediT authorship contribution statement Destination: mk:H1_7 Item: Title: Declaration of Competing Interest Destination: mk:HH1_3 Item: Title: Data availability Destination: datalink4 Item: Title: Acknowledgments Destination: mk:HH1_5 Item: Title: Consent for publication Destination: mk:H1_8 Item: Title: References Destination: mk:HH2_1 Info: Title: Deep learning applications in single-cell genomics and transcriptomics data analysis Author: Nafiseh Erfanian Subject: Biomedicine & Pharmacotherapy, 165 (2023) 115077. doi:10.1016/j.biopha.2023.115077 Keywords: Deep Learning,Single-cell omics,Genomics,Transcriptomics,Multi-omics integration Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Fri Aug 11 14:13:41 CEST 2023 ModDate: Fri Aug 11 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Biomedicine & Pharmacotherapy, 165 (2023) 115077. doi:10.1016/j.biopha.2023.115077 Deep Learning Single-cell omics Genomics Transcriptomics Multi-omics integration Deep learning applications in single-cell genomics and transcriptomics data analysis Nafiseh Erfanian A. Ali Heydari Adib Miraki Feriz Pablo Iañez Afshin Derakhshani Mohammad Ghasemigol Mohsen Farahpour Seyyed Mohammad Razavi Saeed Nasseri Hossein Safarpour Amirhossein Sahebkar journal Biomedicine & Pharmacotherapy © 2023 The Author(s). Published by Elsevier Masson SAS. 0753-3322 165 1 September 2023 2023-09-01 115077 115077 10.1016/j.biopha.2023.115077 https://doi.org/10.1016/j.biopha.2023.115077 2010-04-23 true 10.1016/j.biopha.2023.115077 elsevier.com sciencedirect.com http://creativecommons.org/licenses/by/4.0/ VoR 10.1016/j.biopha.2023.115077 noindex 2010-04-23 true 12th August 2023 sciencedirect.com elsevier.com Elsevier 2023-08-11T18:59:09 2023-08-11T12:13:41 2023-08-11T18:59:09 True 12th August 2023 Acrobat Distiller 8.1.0 (Windows) Deep Learning,Single-cell omics,Genomics,Transcriptomics,Multi-omics integration uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 117, 571, 197, 582 Flags: Print Destination: 2417 Annotation: Subtype: Link Rect: 197, 576, 204, 586 Flags: Print Destination: 2417 Annotation: Subtype: Link Rect: 205, 571, 300, 582 Flags: Print Destination: 2417 Annotation: Subtype: Link Rect: 300, 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