3e50ba650fe9cae4387fe975b3b69a10 Genetic_characterization_of_the_ALFA.pdf 7a86ff13e70d8b327be0ef7a869fba8f399c4028 Genetic_characterization_of_the_ALFA.pdf a56b0d905e973b81ba39357af4e7241e16b5eac929fb9b55a018674b6d417db8 Genetic_characterization_of_the_ALFA.pdf Title: Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer's continuum Subject: Alzheimer's & Dementia 0.0 Keywords: Author: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 10.0.0 (Windows); modified using iText 4.2.0 by 1T3XT CreationDate: Mon Dec 11 10:44:43 2023 CET ModDate: Thu Feb 22 17:53:52 2024 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1942224 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LCFIOH+Lato-Regular Type 1C Custom yes yes yes 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'alz13537-supitem-0024' cannot be found ID: PDF-HUL-122 Offset: 1940587 MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer’s continuum Destination: chapter..1 Children: Item: Title: Abstract Destination: section*.2 Item: Title: 1 | BACKGROUND Destination: section..1.1 Item: Title: 2 | METHODS Destination: section..1.2 Children: Item: Title: 2.1 | Design Destination: subsection..1.2.1 Item: Title: 2.2 | Genetic quality control and imputation Destination: subsection..1.2.2 Item: Title: 2.3 | Statistical analysis Destination: subsection..1.2.3 Item: Title: 3 | RESULTS Destination: section..1.3 Children: Item: Title: 3.1 | Demographic characteristics and APOE genotype distribution Destination: subsection..1.3.1 Item: Title: 3.2 | Polygenic characterization of ALFA participants Destination: subsection..1.3.2 Item: Title: 3.3 | Characteristics of individuals with AD genetic predisposition Destination: subsection..1.3.3 Item: Title: 3.4 | AD genetic risk prediction in the whole disease spectrum Destination: subsection..1.3.4 Item: Title: 4 | DISCUSSION Destination: section..1.4 Item: Title: ACKNOWLEDGMENTS Destination: section*.4 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: section*.6 Item: Title: CONSENT STATEMENT Destination: section*.8 Item: Title: ORCID Destination: section*.10 Item: Title: REFERENCES Destination: section*.12 Item: Title: SUPPORTING INFORMATION Destination: section*.14 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: 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