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4e430093582c9fb21a5cca3412702390309d64808db4e35a90ee8d02f4f5c41d  Immune_restoration.pdf

Title:          Immune restoration with ibrutinib plus venetoclax in first-line chronic lymphocytic leukemia: the phase 2 CAPTIVATE study
Subject:        BLOOD ADVANCES, 7 (2023) 5294-5303. doi:10.1182/bloodadvances.2023010236
Author:         Carol Moreno∗
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      Title: Immune restoration with ibrutinib plus venetoclax in first-line chronic lymphocytic leukemia: the phase 2 CAPTIVATE study
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        Title: Introduction
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       Item: 
        Title: Materials and methods
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         Item: 
          Title: Study design and treatment
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         Item: 
          Title: Immunophenotyping
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         Item: 
          Title: BCL-2 sensitization
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         Item: 
          Title: Safety analysis
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         Item: 
          Title: Statistical analysis
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        Title: Results
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          Title: Baseline characteristics and patient disposition
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         Item: 
          Title: Ibrutinib treatment sensitizes CLL cells to venetoclax
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         Item: 
          Title: Addition of venetoclax to ibrutinib drives a rapid decrease of circulating CLL cells
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         Item: 
          Title: B-cell count recovery after cycle 16 varied based on the randomized treatment arm
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         Item: 
          Title: Abnormal counts of T cells normalized to healthy donor levels
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         Item: 
          Title: Ibrutinib plus venetoclax drives recovery of classical monocytes and DCs
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          Title: Analysis from GLOW confirms the changes in immune cell subsets observed in CAPTIVATE
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         Item: 
          Title: Treatment-emergent infections decrease over time regardless of randomized treatment
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        Title: Discussion
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        Title: Authorship
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        Title: References
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    Title: Immune restoration with ibrutinib plus venetoclax in first-line chronic lymphocytic leukemia: the phase 2 CAPTIVATE study
    Author: Carol Moreno∗
    Subject: BLOOD ADVANCES, 7 (2023) 5294-5303. doi:10.1182/bloodadvances.2023010236
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  Checksum: c791f0dd
   Type: CRC32
  Checksum: ae24b87f55f94b8581004d7739219266
   Type: MD5
  Checksum: 87e93044fd86ca173d643038913b7314d5716c03
   Type: SHA-1
  Checksum: 4e430093582c9fb21a5cca3412702390309d64808db4e35a90ee8d02f4f5c41d
   Type: SHA-256