1427b1ccc4a0db771fe3c17a51af6cb9 Genetic_and_epigenetic_defects.pdf fb1e182af4e40b0853958a25e53514928a6898e3 Genetic_and_epigenetic_defects.pdf 31982dba0068c892eb2df705e5d06e73509562223a0dba9d3833bd7bb6541b05 Genetic_and_epigenetic_defects.pdf Title: Genetic and epigenetic defects of the RNA modification machinery in cancer Subject: Trends in Genetics, 39 (2023) 74-88. doi:10.1016/j.tig.2022.10.004 Keywords: cancer; genetics; epigenetics; RNA modifications; RNA-modifying proteins Author: Ines Orsolic Creator: Elsevier CreationDate: Fri Dec 9 05:33:36 2022 CET ModDate: Fri Dec 9 05:33:36 2022 CET Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 15 Encrypted: no Page size: 602.929 x 782.929 pts Page rot: 0 File size: 1742686 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- FODLED+AdvTTb0eaa911 Type 1C WinAnsi yes yes no 850 0 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Item: Title: m6A in human cancers Destination: s0020 Item: Title: N1-methyladenosine (m1A) modification Destination: s0025 Children: Item: Title: m1A as a diagnostic and prognostic marker Destination: s0030 Item: Title: N5-methylcytosine (m5C) modification Destination: s0035 Children: Item: Title: m5C in the context of cancer Destination: s0040 Item: Title: Pseudouridylation (Ψ) Destination: s0045 Children: Item: Title: Ψ in the context of cancer Destination: s0050 Item: Title: 2′-O-methylation (2′-O-Me) Destination: s0055 Children: Item: Title: 2′-O-Me in the context of cancer Destination: s0060 Item: Title: A–I RNA editing Destination: s0065 Children: Item: Title: Changes in A–I RNA-editing machinery in human diseases Destination: s0070 Item: Title: Other cancer-associated tRNA modifications Destination: s0075 Item: Title: Concluding remarks Destination: s0080 Item: Title: Acknowledgments Destination: s0090 Item: Title: Declaration of interests Destination: s0095 Item: Title: References Destination: section19 Info: Title: Genetic and epigenetic defects of the RNA modification machinery in cancer Author: Ines Orsolic Subject: Trends in Genetics, 39 (2023) 74-88. doi:10.1016/j.tig.2022.10.004 Keywords: cancer; genetics; epigenetics; RNA modifications; RNA-modifying proteins Creator: Elsevier CreationDate: Fri Dec 09 05:33:36 CET 2022 ModDate: Fri Dec 09 05:33:36 CET 2022 ID: 0x59d734a6368068e886baf0999c0fcd62, 0x2aadd0354ff71642b58cad061633983c Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1468 ImageHeight: 1372 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1493 ImageHeight: 1374 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: FODMMK+AdvTTc685db85 FontSubset: true FirstChar: 40 LastChar: 122 FontDescriptor: 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FODLHJ+AdvTT1895a33e+fb Flags: Symbolic FontBBox: 0, 0, 375, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FODLHK+AdvTT1895a33e+20 FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: FODLHK+AdvTT1895a33e+20 Flags: Symbolic FontBBox: -197, -145, 1395, 739 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FODMLK+AdvTTe0754e31.B+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: FODMLK+AdvTTe0754e31.B+03 Flags: Symbolic FontBBox: -958, -229, 927, 958 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: FODMFJ+ArialNarrow FontSubset: true FirstChar: 49 LastChar: 121 FontDescriptor: FontName: FODMFJ+ArialNarrow Flags: Nonsymbolic FontBBox: -182, -307, 1000, 1086 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.tig.2022.10.004 Genetic and epigenetic defects of the RNA modification machinery in cancer Ines Orsolic Arnaud Carrier Manel Esteller cancer genetics epigenetics RNA modifications RNA-modifying proteins Trends in Genetics, 39 (2023) 74-88. doi:10.1016/j.tig.2022.10.004 The Author(s) journal Trends in Genetics (c) 2022 The Author(s) All rights reserved 0168-9525 39 1 January 2023 74-88 74 88 10.1016/j.tig.2022.10.004 https://doi.org/10.1016/j.tig.2022.10.004 2010-04-23 true 10.1016/j.tig.2022.10.004 elsevier.com sciencedirect.com VoR 7.0 10.1016/j.tig.2022.10.004 noindex 2010-04-23 true elsevier.com sciencedirect.com Elsevier 2022-12-09T04:33:36Z 2022-12-09T04:33:36Z 2022-12-09T04:33:36Z True cancer; genetics; epigenetics; RNA modifications; RNA-modifying proteins uuid:991bf1d5-e8ec-4591-b709-d5935557b419 uuid:2f3b3d1c-82a9-4516-a619-17a04f34c577 Pages: Page: Label: 74 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 113, 583, 118, 593 Destination: 794 Annotation: Subtype: Link Rect: 199, 583, 203, 593 Destination: 794 Annotation: Subtype: Link Rect: 300, 580, 309, 589 Annotation: 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