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     Item: 
      Title: Characterization of the endotheliopathy, innate-­immune activation and hemostatic imbalance underlying CAR-­T cell toxicities: laboratory tools for an early and differential diagnosis
      Children: 
       Item: 
        Title: Abstract
       Item: 
        Title: Introduction
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Study population and sample collection
         Item: 
          Title: Soluble levels of endothelial dysfunction biomarkers
         Item: 
          Title: Evaluation of innate immune activation
         Item: 
          Title: Hemostasis and fibrinolysis assessment
         Item: 
          Title: Statistical analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Patients’ characteristics
         Item: 
          Title: Endotheliopathy biomarkers in CAR-T cells-treated patients versus healthy controls
         Item: 
          Title: Basal endotheliopathy assessment depending on previous clinical conditions
         Item: 
          Title: Increase of levels of endothelial activation markers after construct’s infusion
         Item: 
          Title: CAR-T-related toxicity and endothelial activation
         Item: 
          Title: Potential role of endothelial and innate-immune activation biomarkers for the prediction of the CAR-T cell toxicity and its severity
         Item: 
          Title: Differentiation between CAR-T cell-related toxicities and septic syndromes
         Item: 
          Title: Impact of the immunosuppressant treatment on endotheliopathy biomarkers
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        Title: Discussion
       Item: 
        Title: Conclusions
       Item: 
        Title: References
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       Rect: 539, 379, 554, 370
      Annotation: 
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       Rect: 322, 370, 406, 362
      Annotation: 
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       Rect: 447, 345, 459, 336
      Annotation: 
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       Rect: 446, 319, 528, 310
      Annotation: 
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       Rect: 322, 285, 363, 276
      Annotation: 
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       Rect: 516, 268, 539, 259
      Annotation: 
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       Rect: 322, 259, 377, 250
      Annotation: 
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       Rect: 349, 242, 448, 233
      Annotation: 
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       Rect: 483, 234, 542, 225
      Annotation: 
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       Rect: 448, 208, 483, 199
      Annotation: 
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       Rect: 435, 182, 502, 173
      Annotation: 
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       Rect: 357, 157, 385, 148
      Annotation: 
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       Rect: 373, 131, 458, 122
      Annotation: 
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       Rect: 464, 114, 493, 105
      Annotation: 
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       Rect: 437, 97, 458, 88
  Checksum: 06904961
   Type: CRC32
  Checksum: 519b98f929500ebc0b3bed725abbfd1e
   Type: MD5
  Checksum: b0b6217ff06c12e0bb398d8077f80c4cf08ed00e
   Type: SHA-1
  Checksum: 611966da34dfd5131bb1f0eb9036b756d7f987c781b7935e04c305fd0171e957
   Type: SHA-256