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Obtention, characterization, and hazard effects of true-to-life PLA-NPLs Subject: Journal of Hazardous Materials, 458 (2023) 131899. doi:10.1016/j.jhazmat.2023.131899 Keywords: Nanoplastics,Teabags,Polylactic acid,Gastrointestinal tract,Food contaminants Author: Gooya Banaei Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Thu Jul 20 16:50:48 2023 CEST ModDate: Thu Jul 20 17:02:32 2023 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 7485857 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KPNHKF+CharisSIL CID TrueType Identity-H yes yes yes 714 0 WJZZWE+STIX-Regular Type 1C Custom yes yes yes 719 0 PFNGJQ+Univers Type 1C Builtin yes yes yes 724 0 BUPQFA+TeX_CM_Maths_Symbols Type 1C Builtin yes yes yes 728 0 NNLAUQ+TeX_CM_Roman Type 1C Builtin yes yes yes 732 0 GGEDHC+CharisSIL-Italic CID TrueType Identity-H yes yes yes 736 0 XGIURF+CharisSIL CID TrueType Identity-H yes yes yes 705 0 ZPXCOX+CharisSIL-Bold CID TrueType Identity-H yes yes yes 308 0 BIPSBH+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 313 0 FCHDYL+CharisSIL-Italic CID TrueType Identity-H yes yes yes 301 0 LIRLLA+STIX-Italic Type 1C Custom yes yes yes 318 0 NTMBZO+TeX_CM_Maths_Italic Type 1C Builtin yes yes yes 323 0 IXNVQQ+STIXGeneral Type 1C Custom yes yes yes 40 0 YUDRDX+CharisSIL-BoldItalic CID TrueType Identity-H yes yes yes 144 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-02-10 02:32:41 CET RepresentationInformation: 1-s2.0-S0304389423011822-main.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-02-08 01:35:55 CET Size: 7485857 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'sec0135' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'sec0135' cannot be found ID: PDF-HUL-122 Offset: 7447084 MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 804 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: The release of polylactic acid nanoplastics (PLA-NPLs) from commercial teabags. Obtention, characterization, and hazard eff ... Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Materials and methods Destination: mk:H1_2 Children: Item: Title: 2.1 PLA nanoplastics obtention Destination: mk:H2_1 Item: Title: 2.2 PLA nanoplastics characterization Destination: mk:H2_2 Item: Title: 2.3 Scanning electron microscopy (SEM) to visualize teabag surfaces and dispersions Destination: mk:H2_3 Item: Title: 2.4 Particles’ shape analysis with transmission electron microscopy (TEM) Destination: mk:H2_4 Item: Title: 2.5 Chemical identification using Fourier Transform Infrared Spectroscopy (FTIR) Destination: mk:H2_5 Item: Title: 2.6 Hydrodynamic size determination by using Dynamic light scattering (DLS) and laser Doppler velocimetry (LDV) Destination: mk:H2_6 Item: Title: 2.7 Quantification of the released nanoparticles by nanoparticle tracking analysis (NTA) Destination: mk:H2_7 Item: Title: 2.8 Cell culture conditions, in vitro model development, and exposure to PLA-NPLs Destination: mk:H2_8 Item: Title: 2.9 Cell internalization by confocal microscopy Destination: mk:H2_9 Item: Title: 2.10 Internalization studies by flow cytometry Destination: mk:H2_10 Item: Title: 2.11 Detection of intracellular reactive oxygen species (ROS) Destination: mk:H2_11 Item: Title: 2.12 Evaluation of the barrier’s integrity and permeability Destination: mk:H2_12 Item: Title: 2.13 Statistical analysis Destination: mk:H2_13 Item: Title: 3 Results and discussion Destination: mk:H1_3 Children: Item: Title: 3.1 Characterization of teabags filters Destination: mk:H2_14 Item: Title: 3.2 Characterization of the released particles Destination: mk:H2_15 Item: Title: 3.3 Quantification of the teabag leachate particles Destination: mk:H2_16 Item: Title: 3.4 In vitro fate and bio-interactions of PLA-NPLs Destination: mk:H2_17 Item: Title: 3.5 Effects of PLA-NPLs in the in vitro model of the intestinal barrier (Caco-2/HT29 cells) Destination: mk:H2_18 Item: Title: 4 Conclusions Destination: mk:H1_4 Item: Title: Environmental implication Destination: mk:H1_5 Item: Title: Author contribution statement Destination: mk:H1_6 Item: Title: CRediT authorship contribution statement Destination: mk:H1_7 Item: Title: Declaration of Competing Interest Destination: mk:HH1_3 Item: Title: Acknowledgments Destination: mk:HH1_4 Item: Title: Appendix A Supporting information Destination: mk:H1_8 Item: Title: References Destination: mk:HH2_1 Info: Title: The release of polylactic acid nanoplastics (PLA-NPLs) from commercial teabags. Obtention, characterization, and hazard effects of true-to-life PLA-NPLs Author: Gooya Banaei Subject: Journal of Hazardous Materials, 458 (2023) 131899. doi:10.1016/j.jhazmat.2023.131899 Keywords: Nanoplastics,Teabags,Polylactic acid,Gastrointestinal tract,Food contaminants Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Thu Jul 20 16:50:48 CEST 2023 ModDate: Thu Jul 20 17:02:32 CEST 2023 ID: 0x13c2192fd411403001c55dde7ebe6071, 0xdeec1d236cf413d19a001ba6f5333ddf Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: GGEDHC+CharisSIL-Italic Encoding: Identity-H ToUnicode: true Font: BaseFont: YUDRDX+CharisSIL-BoldItalic Encoding: Identity-H ToUnicode: true Font: BaseFont: ZPXCOX+CharisSIL-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: BIPSBH+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Font: BaseFont: KPNHKF+CharisSIL Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: NTMBZO+TeX_CM_Maths_Italic FontSubset: true FirstChar: 1 LastChar: 127 FontDescriptor: FontName: NTMBZO+TeX_CM_Maths_Italic Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: PFNGJQ+Univers FontSubset: true FirstChar: 32 LastChar: 251 FontDescriptor: FontName: PFNGJQ+Univers Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: BUPQFA+TeX_CM_Maths_Symbols FontSubset: true FirstChar: 1 LastChar: 138 FontDescriptor: FontName: BUPQFA+TeX_CM_Maths_Symbols Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: IXNVQQ+STIXGeneral FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: IXNVQQ+STIXGeneral Flags: Nonsymbolic FontBBox: -178, -443, 2000, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: NNLAUQ+TeX_CM_Roman FontSubset: true FirstChar: 1 LastChar: 128 FontDescriptor: FontName: NNLAUQ+TeX_CM_Roman Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: LIRLLA+STIX-Italic FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LIRLLA+STIX-Italic Flags: Nonsymbolic, Italic FontBBox: -970, -305, 1429, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: WJZZWE+STIX-Regular FontSubset: true FirstChar: 1 LastChar: 8 FontDescriptor: FontName: WJZZWE+STIX-Regular Flags: Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true CIDFontType2: Font: BaseFont: GGEDHC+CharisSIL-Italic CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: GGEDHC+CharisSIL-Italic Flags: Nonsymbolic, Italic FontBBox: -716, -533, 1627, 1318 FontFile2: true Font: BaseFont: YUDRDX+CharisSIL-BoldItalic CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: YUDRDX+CharisSIL-BoldItalic Flags: Nonsymbolic, Italic, ForceBold FontBBox: -741, -533, 1795, 1320 FontFile2: true Font: BaseFont: ZPXCOX+CharisSIL-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: ZPXCOX+CharisSIL-Bold Flags: Nonsymbolic, ForceBold FontBBox: -720, -533, 1759, 1320 FontFile2: true Font: BaseFont: BIPSBH+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: BIPSBH+TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true Font: BaseFont: KPNHKF+CharisSIL CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: KPNHKF+CharisSIL Flags: Nonsymbolic FontBBox: -692, -533, 1623, 1319 FontFile2: true XMP: http://creativecommons.org/licenses/by/4.0/ elsevier.com sciencedirect.com true 10.1016/j.jhazmat.2023.131899 2010-04-23 application/pdf 10.1016/j.jhazmat.2023.131899 Elsevier B.V. Journal of Hazardous Materials, 458 (2023) 131899. doi:10.1016/j.jhazmat.2023.131899 Nanoplastics Teabags Polylactic acid Gastrointestinal tract Food contaminants The release of polylactic acid nanoplastics (PLA-NPLs) from commercial teabags. Obtention, characterization, and hazard effects of true-to-life PLA-NPLs Gooya Banaei Alba García-Rodríguez Alireza Tavakolpournegari Juan Martín-Pérez Aliro Villacorta Ricard Marcos Alba Hernández VoR 20th July 2023 Acrobat Distiller 8.1.0 (Windows) Nanoplastics,Teabags,Polylactic acid,Gastrointestinal tract,Food contaminants 20th July 2023 sciencedirect.com elsevier.com true 2010-04-23 10.1016/j.jhazmat.2023.131899 noindex journal © 2023 The Author(s). Published by Elsevier B.V. 2023-09-15 15 September 2023 10.1016/j.jhazmat.2023.131899 0304-3894 131899 Journal of Hazardous Materials 131899 https://doi.org/10.1016/j.jhazmat.2023.131899 458 2023-07-20T14:50:48 Elsevier 2023-07-20T15:02:32 2023-07-20T15:02:32 uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 True Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 104, 559, 110, 569 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 111, 554, 230, 565 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 230, 559, 236, 569 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 237, 554, 374, 565 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 374, 554, 480, 565 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 111, 546, 118, 556 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 118, 541, 199, 552 Flags: Print Destination: 686 Annotation: Subtype: Link Rect: 199, 546, 205, 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