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Title:           Dopamine receptors D1 and D2 show prognostic significance and potential therapeutic applications for endometrial cancer patients
Subject:         Gynecologic Oncology, 176 (2023) 25-35. doi:10.1016/j.ygyno.2023.06.019
Keywords:        Endometrial cancer; Dopamine receptor; DRD1; DRD2; Prognostic value; Neuromodulation; Targeted therapy; Drug repurposing
Author:          Pia Español
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      Title: Dopamine receptors D1 and D2 show prognostic significance and potential therapeutic applications for endometrial cancer pat...
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        Title: 1. Introduction
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        Title: 2. Methods
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          Title: 2.1. Patient cohort and samples
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            Title: 2.1.1. Immunohistochemistry
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            Title: 2.1.2. Statistical analysis
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          Title: 2.2. In vitro experiments
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            Title: 2.2.1. Endometrial tumor cell lines
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            Title: 2.2.2. Gene expression of dopamine receptors
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            Title: 2.2.3. Cell viability assay
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          Title: 3.1. Clinical characteristics of the patient's cohort
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          Title: 3.2. ADRβ2 expression is reduced in endometrial tumors and has no association with clinico-pathological variables
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          Title: 3.3. Low DRD1 expression in endometrial tumors is associated with higher tumor size and stage
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          Title: 3.4. DRD2 expression is associated with poor prognosis in our patient cohort
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          Title: 3.5. The combined activation of DRD1 and blockage of DRD2 reduced cellular viability in EC tumor cells
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        Title: Declaration of Competing Interest
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        Title: References
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    Keywords: Endometrial cancer; Dopamine receptor; DRD1; DRD2; Prognostic value; Neuromodulation; Targeted therapy; Drug repurposing
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   Type: CRC32
  Checksum: da0f42a7a61c7674fd72e168684cf7b1
   Type: MD5
  Checksum: 4b0fe010ef64bac2da93583762aa470459b408e6
   Type: SHA-1
  Checksum: 704a5c57a25ed2058f41f28989c514caf89a9ec1ff3b1d0e72f4a3836118405a
   Type: SHA-256