f5067fcae21a35fee1503c87bf7adf4d 301712.pdf 73aa5682b671decfc8145566d5376877c41e9136 301712.pdf 863a308dca43dd0ba898814b8e6f82e88af65072fe7a7f0546ae694d09cd800e 301712.pdf Title: Tildrakizumab improves high burden skin symptoms, impaired sleep and quality of life of moderate‐to‐severe plaque psoriasis patients in conditions close to clinical practice Subject: Acad Dermatol Venereol 2023.37:2004-2015 Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0; modified using iText 4.2.0 by 1T3XT CreationDate: Thu Aug 31 03:00:09 2023 CEST ModDate: Thu Oct 24 11:12:17 2024 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 350131 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- TBIJSW+MinionPro-Bold Type 1C 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Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-US Outlines: Item: Title: Tildrakizumab improves high burden skin symptoms, impaired sleep and quality of life of moderate-­to-­severe plaque psoriasis patients in conditions close to clinical practice Children: Item: Title: Abstract Item: Title: INTRODUCTION Item: Title: MATERIALS AND METHODS Children: Item: Title: Study design Item: Title: Patients Item: Title: Procedures Item: Title: Statistical analysis Item: Title: RESULTS Children: Item: Title: Subject disposition and baseline characteristics Item: Title: Clinical response Children: Item: Title: Psoriasis area and severity index (PASI) Item: Title: Body surface area (BSA) Item: Title: Physician's global assessment (PGA) Item: Title: Heath-­related quality of life Children: Item: Title: Dermatology life quality index (DLQI) and DLQI-­relevant (DLQI-­R) Item: Title: Skindex-­16 Item: Title: Additional patient-­reported outcomes Children: Item: Title: Pruritus-­NRS, Pain-­NRS and Scaling-­NRS Item: Title: MOS-­Sleep Item: Title: Work productivity and activity impairment (WPAI) Item: Title: Patient benefit index (PBI) Item: Title: Patient's treatment satisfaction (TSQM) Item: Title: Safety assessments Item: Title: DISCUSSION Item: Title: ACKNO​WLE​DGE​MENTS Item: Title: FUNDING INFORMATION Item: Title: CONFLICT OF INTEREST STATEMENT Children: Item: Title: DATA AVAILABILITY STATEMENT Item: Title: ETHICS STATEMENT Item: Title: REFERENCES Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 110 ImageHeight: 14 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