e9e4f65b920b9f10b5738c20e8bfb653 302818.pdf 2a23117cfea67c3e3221318b1c325e8e138651e2 302818.pdf da83b096467afadb2231896a46bcb0c8d3cf944112e69b231fa9d26cb961c5cd 302818.pdf Title: Comparison and Evaluation of Outcomes of Ureteroscopyand Stone Laser Fragmentation in Extremes of Age Groups(10 Years and 80 Years of Age): A Retrospective Comparative Analysis of over 15 Years from 2 Tertiary European Centres Subject: Aim: To assess and compare the outcomes associated with ureteroscopy and laser fragmentation (URSL) for extremes of age group (10 and 80 years). Methods: Retrospective consecutive data were collected from two European centres for all paediatric patients 10 undergoing URSL over a 15-year period (group 1). It was compared to consecutive data for all patients 80 years (group 2). Data were collected for patient demographics, stone characteristics, operative details, and clinical outcomes. Results: A total of 168 patients had 201 URSL procedures during this time(74 and 94 patients in groups 1 and 2 respectively). The mean age and stone sizes were 6.1 years and 85 years, and 9.7 mm and 13 mm for groups 1 and 2 respectively. While the SFR was slightly higher in group 2 (92.5% versus 87.8%, p = 0.301), post-operative stent rate was also significantly higher in the geriatric population (75.9% versus 41.2%, p = 0.0001). There was also no significant difference in pre-operative stenting (p = 0.886), ureteric access sheath use (UAS) (p = 0.220) and post-operative complications. Group 1 had an intervention rate of 1.3/patient as compared to 1.1/patient in group 2. The overall complications were 7.2% and 15.3% in groups 1 and 2 respectively (0.069), with 1 Clavien IV complication related to post-operative sepsis and brief ICU admission in group 2. Conclusion: The paediatric population had a marginally higher incidence of repeat procedure, but the overall SFR and complications were similar, and post-operative stent insertion rates were much better compared to geriatric patients. URSL is a safe procedure in the extremes of age groups with no difference in the overall outcomes between the two groups. Keywords: ureteroscopy; laser; kidney calculi; paediatric; urolithiasis; stent; elderly Author: Mriganka M. Sinha, Amelia Pietropaolo, Yesica Quiroz Madarriaga, Erika Llorens de Knecht, Anna Bujons Tur, Stephen Griffin and Bhaskar K. Somani Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Mon Feb 20 07:09:07 2023 CET ModDate: Mon Feb 20 07:10:50 2023 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 266486 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KNLZHK+VnURWPalladioL Type 1 Custom yes yes no 10 0 WNHXHH+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 WCBEOT+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 KOSUXD+CMSY10 Type 1 Builtin yes yes no 24 0 VKDXPR+URWPalladioL-Ital Type 1 Custom yes yes no 28 0 IEKGBM+CMBSY10 Type 1 Builtin yes yes no 32 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 50 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 53 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes no 81 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-11-16 02:44:41 CET RepresentationInformation: 302818.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-11-15 09:37:29 CET Size: 266486 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 221 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Item: Title: Results Destination: section.3 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.5 Info: Title: Comparison and Evaluation of Outcomes of Ureteroscopyand Stone Laser Fragmentation in Extremes of Age Groups(10 Years and 80 Years of Age): A Retrospective Comparative Analysis of over 15 Years from 2 Tertiary European Centres Author: Mriganka M. Sinha, Amelia Pietropaolo, Yesica Quiroz Madarriaga, Erika Llorens de Knecht, Anna Bujons Tur, Stephen Griffin and Bhaskar K. Somani Subject: Aim: To assess and compare the outcomes associated with ureteroscopy and laser fragmentation (URSL) for extremes of age group (10 and 80 years). Methods: Retrospective consecutive data were collected from two European centres for all paediatric patients 10 undergoing URSL over a 15-year period (group 1). It was compared to consecutive data for all patients 80 years (group 2). Data were collected for patient demographics, stone characteristics, operative details, and clinical outcomes. Results: A total of 168 patients had 201 URSL procedures during this time(74 and 94 patients in groups 1 and 2 respectively). The mean age and stone sizes were 6.1 years and 85 years, and 9.7 mm and 13 mm for groups 1 and 2 respectively. While the SFR was slightly higher in group 2 (92.5% versus 87.8%, p = 0.301), post-operative stent rate was also significantly higher in the geriatric population (75.9% versus 41.2%, p = 0.0001). There was also no significant difference in pre-operative stenting (p = 0.886), ureteric access sheath use (UAS) (p = 0.220) and post-operative complications. Group 1 had an intervention rate of 1.3/patient as compared to 1.1/patient in group 2. The overall complications were 7.2% and 15.3% in groups 1 and 2 respectively (0.069), with 1 Clavien IV complication related to post-operative sepsis and brief ICU admission in group 2. Conclusion: The paediatric population had a marginally higher incidence of repeat procedure, but the overall SFR and complications were similar, and post-operative stent insertion rates were much better compared to geriatric patients. URSL is a safe procedure in the extremes of age groups with no difference in the overall outcomes between the two groups. 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