aa07ad7a1d26e857bf3cb4c54347bcd7 303441.pdf 7339683d033c2463265e108c4d2c89a46b237b16 303441.pdf f3ac918dea4bce88b49edfd248605268359e5b8a3402184ba53984c1056f096a 303441.pdf Title: Rituximab treatment in myasthenia gravis Subject: Myasthenia gravis (MG) is a chronic autoimmune disease mediated by antibodies against post-synaptic proteins of the neuromuscular junction. Author: Ana Vesperinas-Castro; Elena Cortés-Vicente Creator: Adobe InDesign 14.0 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Wed Sep 27 09:42:18 2023 CEST ModDate: Wed Sep 27 09:42:30 2023 CEST Custom Metadata: no Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 484382 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- TCPVGG+MuseoSans-500 Type 1C Custom yes yes yes 8 0 RZQJEK+MuseoSans-300 Type 1C Custom yes yes yes 689 0 OXCROQ+MuseoSans-700 Type 1C Custom yes yes yes 92 0 NTSLAS+MinionPro-Regular Type 1C Custom yes yes yes 9 0 JNPNWA+MuseoSans-300Italic Type 1C WinAnsi yes yes yes 690 0 IJFHIC+MinionPro-Bold Type 1C WinAnsi yes yes yes 93 0 GGBVGG+STIXGeneral-Regular Type 1C Custom yes yes yes 94 0 EDCJEK+MinionPro-It Type 1C Custom yes yes yes 95 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-11-23 02:45:49 CET RepresentationInformation: 303441.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-11-22 09:18:41 CET Size: 484382 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 1698 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-GB Outlines: Item: Title: Rituximab treatment in myasthenia gravis Children: Item: Title: 1. Introduction Item: Title: 2. Mechanism of action Item: Title: 3. Drug history and indications Item: Title: 4. Use of rituximab in myasthenia gravis Children: Item: Title: 4.1. Rituximab treatment in patients with anti-AChR antibodies Item: Title: 4.1.1. Evidence of use Item: Title: 4.1.2. Recommendation of use Item: Title: 4.2. Rituximab treatment in patients with anti-MuSK antibodies Item: Title: 4.2.1. Evidence of use Item: Title: 4.2.2. Recommendation of use Item: Title: 4.3. Rituximab treatment in seronegative patients Item: Title: 4.3.1. Evidence of use Item: Title: 4.3.2. Recommendation of use Item: Title: 4.4. Rituximab treatment in juvenile myasthenia gravis Item: Title: 4.4.1. Evidence of use Item: Title: 4.4.2. Recommendation of use Item: Title: 5. The physiopathology behind the evidence Item: Title: 6. Regimen of administration Item: Title: 7. Monitorization after treatment Item: Title: 8. Safety profile Item: Title: 9. Discussion Item: Title: Author contributions Item: Title: References Info: Title: Rituximab treatment in myasthenia gravis Author: Ana Vesperinas-Castro; Elena Cortés-Vicente Subject: Myasthenia gravis (MG) is a chronic autoimmune disease mediated by antibodies against post-synaptic proteins of the neuromuscular junction. Creator: Adobe InDesign 14.0 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Wed Sep 27 10:12:18 CEST 2023 ModDate: Wed Sep 27 10:12:30 CEST 2023 ID: 0x200b1a9e1bdc9a488544581b2d08ef25, 0xd6fc6f6e216a91483b85a2b821072276 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: RZQJEK+MuseoSans-300 FontSubset: true FirstChar: 29 LastChar: 243 FontDescriptor: FontName: RZQJEK+MuseoSans-300 Flags: Nonsymbolic FontBBox: -118, -210, 1088, 883 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: JNPNWA+MuseoSans-300Italic FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: JNPNWA+MuseoSans-300Italic Flags: Nonsymbolic FontBBox: -245, -210, 1030, 883 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: TCPVGG+MuseoSans-500 FontSubset: true FirstChar: 29 LastChar: 233 FontDescriptor: FontName: TCPVGG+MuseoSans-500 Flags: Nonsymbolic FontBBox: -121, -210, 1088, 892 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