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Title:           Brainstem neuromelanin and iron MRI reveals a precise signature for idiopathic and LRRK2 Parkinson’s disease
Subject:         npj Parkinson’s Disease, doi:10.1038/s41531-023-00503-2
Keywords:        
Author:          Martín Martínez
Creator:         Springer
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     Item: 
      Title: Brainstem neuromelanin and iron MRI reveals a precise signature for idiopathic and LRRK2 Parkinson’s disease
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       Item: 
        Title: Introduction
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       Item: 
        Title: Results
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         Item: 
          Title: Subjects’ recruitment and genetic analysis
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         Item: 
          Title: Quantification of NM CR and nVol in SNc and LC
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         Item: 
          Title: Quantification of iron CR and nVol in SNc and RN
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         Item: 
          Title: Quantification of iron in SNc vs. substantia nigra pars reticulata (SNr)
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         Item: 
          Title: Analysis of NM and iron side asymmetry and topographical interaction
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         Item: 
          Title: ROC analyses for evaluation of diagnostic performance
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         Item: 
          Title: Quantitative and diagnostic analysis of early-stage PD
          Destination: B7
         Item: 
          Title: Association between brainstem MRI parameters and demographic and clinical variables in PD
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        Title: Discussion
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        Title: Methods
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          Title: Sample size estimation
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          Title: Subjects
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          Title: Neurological and neuropsychological assessment
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          Title: Genetic analysis
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          Title: Neuroimaging analysis
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            Title: MRI protocol and acquisition
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            Title: Image preprocessing
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           Item: 
            Title: Automatic image segmentation of brainstem structures
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           Item: 
            Title: Intra-subject spatial alignment of NM and iron sequences
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           Item: 
            Title: Quantification of NM and iron in brainstem structures
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           Item: 
            Title: Probabilistic maps of NM and iron content in brainstem nuclei
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            Title: Spatial distribution of NM and iron in the SNc
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          Title: Statistical analyses
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          Title: Reporting summary
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        Title: References
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        Title: Competing interests
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    Author: Martín Martínez
    Subject: npj Parkinson’s Disease, doi:10.1038/s41531-023-00503-2
    Keywords: 
    Creator: Springer
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   Type: CRC32
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