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Title:           Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL
Subject:         eClinicalMedicine, 67 (2024) 102384. doi:10.1016/j.eclinm.2023.102384
Author:          Franz Koenig
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      Title: Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL
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       Item: 
        Title: Introduction
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       Item: 
        Title: Writing approach of this narrative review
        Destination: flink2
       Item: 
        Title: Integrated research platforms are centred on a platform trial master protocol
        Destination: flink3
       Item: 
        Title: Early consultation with regulators can yield an optimised regulatory pathway
        Destination: flink4
       Item: 
        Title: Platform trials enable patient-centric approaches from their inception
        Destination: flink5
       Item: 
        Title: Clinical research networks provide the infrastructure on which the IRP can be established
        Destination: flink6
       Item: 
        Title: Improving efficiency through adaptive clinical trial design
        Destination: flink7
       Item: 
        Title: Master protocols provide the framework for reusable clinical research infrastructures
        Destination: flink8
       Item: 
        Title: Electronic health records can be leveraged to assess trial feasibility and site selection
        Destination: flink9
       Item: 
        Title: Legal frameworks enable effective collaboration across the diverse parties participating in IRPs
        Destination: flink10
       Item: 
        Title: To be sustainable, platform trials require a business plan which creates value for all trial stakeholders
        Destination: flink11
       Item: 
        Title: Platform trials and IRPs must address key gaps in drug development
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       Item: 
        Title: Future directions and remaining challenges
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        Children: 
         Item: 
          Title: Readiness of non-traditional sponsors
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         Item: 
          Title: Data sharing challenges
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         Item: 
          Title: Regulatory requirements lag the regulatory vision
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       Item: 
        Title: Conclusions
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       Item: 
        Title: ContributorsConceptualisation and design: FK, CS, SRN, DM, NM, JMP, MP; Drafting of the article: FK, CS, SRN, DM, JMP, MP;  ...
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        Title: Declaration of interests
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        Title: Acknowledgements
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        Title: Appendix A. Supplementary data
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        Title: References
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   Type: CRC32
  Checksum: b8ec7c7dd682f8c8bf722268f84b828d
   Type: MD5
  Checksum: e9a9f6dbc2615808881a71d0a1d47619b45769c7
   Type: SHA-1
  Checksum: 18566adcf2e60199c6a9018d8b551c2c6331525a6cd36dafb7b8d179fd248ed2
   Type: SHA-256