6a3972b55a546f21888b7bfd659771b2 328568.pdf 841bd547345cccd08a4690744924ae9a12afab01 328568.pdf d58e1dd7132693a53af9958f219fc46d5143c3486d9b454f11f0c4d0ae762e88 328568.pdf Title: Urinary Tract Infections in Men in Primary Care in Catalonia, Spain Subject: Antimicrobial resistance is a major global problem that is primarily driven by the excessive and inappropriate utilization of antibiotics. Urinary tract infections (UTIs) are frequent in primary health care (PHC) and are typically treated with antibiotics. There is ample evidence on the management of this condition in women but not in men. The aim of this study was to describe the epidemiology of UTIs in men in Catalonia, Spain. We conducted a population-based observational cohort study that included male patients diagnosed with UTI within our SIDIAP and CMBD database during the period from 2012 to 2021. UTI diagnoses were grouped into five main groups (cystitis, prostatitis, orchitis and epididymitis, urethritis, and pyelonephritis). Of the 316,762 men with at least one recorded UTI episode, the majority were registered with a diagnosis of cystitis in PHC (212,958 patients). Quinolones were the most commonly recorded treatment for UTIs (between 18.3% and 38.6%, depending on the group), except for urethritis in which a combination of antibiotics (36.7%) was most frequently used. The treatment duration period was between 9 days and 18 days, except for the prostatitis group, in which treatment was extended to 21 days. Urine cultures were documented in up to 30% in the cystitis group. Pyelonephritis was the category linked to most septicemia cases (3.0%). Conclusions: This is the first study to assess UTIs in men using a large PHC database in Spain. The sociodemographic characteristics of our sample are similar to other studies in the literature. In our setting, the use of quinolones for the treatment of UTIs is the most registered, and its duration was between 9 days and 18 days, despite the fact that resistance to quinolones exceeds 20% of the strains in our area. Keywords: urinary tract infection; primary health care; male; anti-bacterial agents; diagnosis; electronic health records Author: Silvia Fernández-García, Ana Moragas Moreno, Maria Giner-Soriano, Rosa Morros, Dan Ouchi, Ana García-Sangenís, Mònica Monteagudo, Ramon Monfà and Carl Llor Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Nov 10 06:39:10 2023 CET ModDate: Fri Nov 10 06:41:28 2023 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 298736 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KORLVE+VnURWPalladioL Type 1 Custom yes yes no 10 0 PLIXHF+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 HRNRNO+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 XSASNH+URWPalladioL-Ital Type 1 Custom yes yes no 24 0 HQCGIP+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 YYFPCJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 47 0 PDTLUH+CMSY10 Type 1 Builtin yes yes no 84 0 BBZMQY+VnURWPalladioL-Italic Type 1 Custom yes yes no 97 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-09-04 04:20:55 CEST RepresentationInformation: 328568.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-09-03 12:33:41 CEST Size: 298736 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 255 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Results Destination: section.2 Children: Item: Title: Population Destination: subsection.2.1 Item: Title: Sociodemographic Characteristics Destination: subsection.2.2 Item: Title: Baseline Clinical Characteristics Destination: subsection.2.3 Item: Title: Characteristics of UTI Episode Destination: subsection.2.4 Item: Title: Discussion Destination: section.3 Item: Title: Materials and Methods Destination: section.4 Children: Item: Title: Study Design and Population Destination: subsection.4.1 Item: Title: Data Collection and Data Sources Destination: subsection.4.2 Item: Title: Study Population Destination: subsection.4.3 Item: Title: Variables and Outcomes Destination: subsection.4.4 Item: Title: Statistical Analysis Destination: subsection.4.5 Item: Title: Ethical Aspects and Data Confidentiality Destination: subsection.4.6 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.6 Info: Title: Urinary Tract Infections in Men in Primary Care in Catalonia, Spain Author: Silvia Fernández-García, Ana Moragas Moreno, Maria Giner-Soriano, Rosa Morros, Dan Ouchi, Ana García-Sangenís, Mònica Monteagudo, Ramon Monfà and Carl Llor Subject: Antimicrobial resistance is a major global problem that is primarily driven by the excessive and inappropriate utilization of antibiotics. Urinary tract infections (UTIs) are frequent in primary health care (PHC) and are typically treated with antibiotics. There is ample evidence on the management of this condition in women but not in men. The aim of this study was to describe the epidemiology of UTIs in men in Catalonia, Spain. We conducted a population-based observational cohort study that included male patients diagnosed with UTI within our SIDIAP and CMBD database during the period from 2012 to 2021. UTI diagnoses were grouped into five main groups (cystitis, prostatitis, orchitis and epididymitis, urethritis, and pyelonephritis). Of the 316,762 men with at least one recorded UTI episode, the majority were registered with a diagnosis of cystitis in PHC (212,958 patients). Quinolones were the most commonly recorded treatment for UTIs (between 18.3% and 38.6%, depending on the group), except for urethritis in which a combination of antibiotics (36.7%) was most frequently used. The treatment duration period was between 9 days and 18 days, except for the prostatitis group, in which treatment was extended to 21 days. Urine cultures were documented in up to 30% in the cystitis group. Pyelonephritis was the category linked to most septicemia cases (3.0%). Conclusions: This is the first study to assess UTIs in men using a large PHC database in Spain. The sociodemographic characteristics of our sample are similar to other studies in the literature. In our setting, the use of quinolones for the treatment of UTIs is the most registered, and its duration was between 9 days and 18 days, despite the fact that resistance to quinolones exceeds 20% of the strains in our area. 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