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Title:           KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir
Subject:         Cell Reports Medicine, 4 (2023) 101202. doi:10.1016/j.xcrm.2023.101202
Author:          Antonio Astorga-Gamaza
Creator:         Elsevier
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Jhove (Rel. 1.28.0, 2023-05-18)
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     Item: 
      Title: KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of th ...
      Destination: titlink1
      Children: 
       Item: 
        Title: Introduction
        Destination: flink1
       Item: 
        Title: Results
        Destination: flink2
        Children: 
         Item: 
          Title: Active HIV transcription associates with higher frequencies of NK cells expressing KLRG1
          Destination: slink3
         Item: 
          Title: HIV infection expands different populations of NK cells expressing KLRG1, and more differentiated cells are maintained afte ...
          Destination: slink4
         Item: 
          Title: KLRG1+ NK cells are functionally impaired in samples from ART individuals
          Destination: slink5
         Item: 
          Title: Antibody intervention enhances the cytotoxic potential of KLRG1+ NK cells at killing HIV-infected cells
          Destination: slink6
         Item: 
          Title: KLRG1 is expressed on CD4+ T cells harboring inducible HIV genomes, and the anti-KLRG1 antibody induces viral reactivation
          Destination: slink7
       Item: 
        Title: Discussion
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        Children: 
         Item: 
          Title: Limitations of the study
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       Item: 
        Title: Supplemental information
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       Item: 
        Title: Acknowledgments
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       Item: 
        Title: Author contributions
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       Item: 
        Title: Declaration of interests
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       Item: 
        Title: Inclusion and diversity
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       Item: 
        Title: References
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       Item: 
        Title: STAR★Methods
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        Children: 
         Item: 
          Title: Key resources table
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         Item: 
          Title: Resource availability
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           Item: 
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           Item: 
            Title: Materials availability
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           Item: 
            Title: Data and code availability
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         Item: 
          Title: Experimental model and study participant details
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          Children: 
           Item: 
            Title: Human subjects
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           Item: 
            Title: Cell lines
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           Item: 
            Title: Plasmids
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         Item: 
          Title: Method details
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          Children: 
           Item: 
            Title: NK cell phenotyping
            Destination: tlink7
           Item: 
            Title: Dimensionality reduction analysis
            Destination: tlink8
           Item: 
            Title: Immunohistochemistry of human lymph nodes
            Destination: tlink9
           Item: 
            Title: Confocal microscopy and quantification
            Destination: tlink10
           Item: 
            Title: NK natural cytotoxicity assay
            Destination: tlink11
           Item: 
            Title: Ex vivo infection of unstimulated PBMCs
            Destination: tlink12
           Item: 
            Title: NK natural cytotoxicity and ADCC against HIV+ cells
            Destination: tlink13
           Item: 
            Title: FACS isolation of KLRG1+ NK cells and CD4+ T cells
            Destination: tlink14
           Item: 
            Title: Viral reactivation in ART-suppressed PWH samples
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           Item: 
            Title: NK killing of cells harboring intact provirus
            Destination: tlink16
           Item: 
            Title: Intact proviral DNA assay (IPDA)
            Destination: tlink17
           Item: 
            Title: Quantification of HIV DNA and RNA by qPCR
            Destination: tlink18
         Item: 
          Title: Quantification and statistical analysis
          Destination: slink16
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    Title: KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir
    Author: Antonio Astorga-Gamaza
    Subject: Cell Reports Medicine, 4 (2023) 101202. doi:10.1016/j.xcrm.2023.101202
    Creator: Elsevier
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    CreationDate: Thu Oct 12 20:27:34 CEST 2023
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               <rdf:li xml:lang="x-default">KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir</rdf:li>
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               <rdf:li>Antonio Astorga-Gamaza</rdf:li>
               <rdf:li>David Perea</rdf:li>
               <rdf:li>Nerea Sanchez-Gaona</rdf:li>
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