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18:23:27 CEST Size: 10890639 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 994 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing Children: Item: Title: Abstract Children: Item: Title: Background: Item: Title: Results: Item: Title: Conclusions: Item: Title: Background Item: Title: Results Children: Item: Title: Population characteristics Item: Title: Dominance accounts for about a quarter of genetic variance of organismal traits Item: Title: Mapping dominance QTLs improves GWAS sensitivity Item: Title: Gene expression is strongly influenced by dominance effects Item: Title: Trans-acting enrichment among dominance eQTLs Item: Title: eQTL hotspots are enriched for dominance effects Item: Title: Dominance enrichment among genes with multiple isoforms Item: Title: Discussion Item: Title: Conclusions Item: Title: Methods Children: Item: Title: Data processing of genotypes, physiological and expression traits in F2 pigs Item: Title: Data processing of genotypes, organismal, and expressional traits in HS rats Item: Title: Data processing of genotypes, organismal, and expressional traits in HS mice Item: Title: Estimation of additive and dominance variance components Item: Title: Detection and classification of QTLs and eQTLs Item: Title: Anchor 23 Item: Title: Acknowledgements Item: Title: References Info: Title: Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing Author: Leilei Cui Subject: 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XQPIRJ+WarnockPro-It30 Flags: Symbolic, SmallCap FontBBox: -50, -191, 796, 708 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: 2023-09-29T01:52:06 Adobe InDesign 15.1 (Windows) 2023-11-20T18:22:33+01:00 2023-11-20T18:22:33+01:00 application/pdf https://doi.org/10.1186/s13059-023-03060-2 BioMed Central Genome Biology, https://doi.org/10.1186/s13059-023-03060-2 Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing Leilei Cui Bin Yang Shijun Xiao Jun Gao Amelie Baud Delyth Graham Martin McBride Anna Dominiczak Sebastian Schafer Regina Lopez Aumatell Carme Mont Albert Fernandez Teruel Norbert Hübner Jonathan Flint Richard Mott Lusheng Huang 10.1186/s13059-023-03060-2 2010-04-23 true springer.com springerlink.com https://doi.org/10.1186/s13059-023-03060-2 10.1186/s13059-023-03060-2 1474-760X journal Genome Biology The Author(s) 2010-04-23 true 10.1186/s13059-023-03060-2 noindex springer.com springerlink.com Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) False uuid:e86e4582-4dbe-4c18-8a7f-9447f60e76e0 uuid:710c878f-75b8-4408-a502-eccba854723d default 1 converted uuid:e86e4582-4dbe-4c18-8a7f-9447f60e76e0 converted to PDF/A-2b pdfToolbox 2023-09-29T04:43:20Z 2 B Richard Mott http://orcid.org/0000-0002-1022-9330 http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. issn Text internal Volume number volume Text internal Issue number number Text internal Starting page startingPage Text internal Ending page endingPage Text external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external Copyright copyright Text http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. DocumentID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. 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