284bc84e09b5a0a4c1230fb469f76112 2023._Open_Respir_Archives_Efficacy_and_Potential_positioning_of_tezepelumab.pdf d3bd8bc864de807f9555dbca1c308d2f764f45ee 2023._Open_Respir_Archives_Efficacy_and_Potential_positioning_of_tezepelumab.pdf 0814ecf69e63c83f3ea62e19837f012f219034d6cec89a31054bef84a9c6d60f 2023._Open_Respir_Archives_Efficacy_and_Potential_positioning_of_tezepelumab.pdf Title: Efficacy and Potential Positioning of Tezepelumab in the Treatment of Severe Asthma Subject: , doi:10.1016/j.opresp.2022.100231 Keywords: Author: Elsevier Creator: Elsevier Producer: Elsevier Editorial Ltda. CreationDate: Mon Mar 27 21:04:06 2023 CEST ModDate: Mon Mar 27 21:05:22 2023 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.28 x 793.7 pts Page rot: 0 File size: 613926 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- HYAXWS+GulliverRM Type 1C Custom yes yes yes 572 0 SFWDLO+Times-Roman Type 1C WinAnsi yes yes no 574 0 TUTKPI+DIN-CondensedBoldA Type 1C WinAnsi yes yes no 576 0 OMWJTV+Univers Type 1C WinAnsi yes yes no 578 0 JKDXOP+OnemtmiguAAAA Type 1C WinAnsi yes yes no 580 0 RGVIKI+MTSY Type 1C Custom yes yes no 583 0 KZRJHM+GulliverIT Type 1C Custom yes yes no 586 0 BMIDVL+GulliverSCOsF Type 1C WinAnsi yes yes no 588 0 KVZEWQ+GulliverBL Type 1C Custom yes yes yes 591 0 KLSYGQ+MATHG-1A Type 1C Custom yes yes no 594 0 STLNZV+OneGulliverA Type 1C WinAnsi yes yes no 477 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-25 02:30:17 CEST RepresentationInformation: 2023._Open_Respir_Archives_Efficacy_and_Potential_positioning_of_tezepelumab.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-22 01:34:32 CEST Size: 613926 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Efficacy and Potential Positioning of Tezepelumab in the Treatment of Severe Asthma Destination: 1 Children: Item: Title: Current severe asthma management in Spain Destination: 1 Item: Title: Justification for new biologics for severe asthma Destination: 1 Item: Title: TSLP: tezepelumab mechanism of action Destination: 1 Children: Item: Title: TSLP Destination: 1 Item: Title: TSLP mechanism of action: binding to its receptor Destination: 1 Item: Title: TSLP production activators Destination: 1 Item: Title: Tezepelumab mechanism of action Destination: 1 Item: Title: Principal tezepelumab clinical trial results Destination: 1 Item: Title: Tezepelumab positioning in clinical practice Destination: 1 Item: Title: Conclusions Destination: 1 Item: Title: Funding Destination: 1 Item: Title: Authors’ contributions Destination: 1 Item: Title: Conflicts of interest Destination: 1 Item: Title: References Destination: 1 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 299 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 121 ImageHeight: 120 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1985 ImageHeight: 1019 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1662 ImageHeight: 1211 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: TUTKPI+DIN-CondensedBoldA FontSubset: true FirstChar: 65 LastChar: 121 FontDescriptor: FontName: TUTKPI+DIN-CondensedBoldA Flags: Nonsymbolic FontBBox: -9, -205, 414, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OMWJTV+Univers FontSubset: true FirstChar: 46 LastChar: 119 FontDescriptor: FontName: OMWJTV+Univers Flags: Nonsymbolic, SmallCap FontBBox: 0, -17, 823, 721 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KLSYGQ+MATHG-1A FontSubset: true FirstChar: 2 LastChar: 4 FontDescriptor: FontName: KLSYGQ+MATHG-1A Flags: Symbolic FontBBox: 0, -252, 761, 809 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: JKDXOP+OnemtmiguAAAA FontSubset: true FirstChar: 44 LastChar: 44 FontDescriptor: FontName: JKDXOP+OnemtmiguAAAA Flags: Nonsymbolic, AllCap FontBBox: 0, -173, 242, 118 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: RGVIKI+MTSY FontSubset: true FirstChar: 2 LastChar: 2 FontDescriptor: FontName: RGVIKI+MTSY Flags: Symbolic FontBBox: 0, 0, 466, 467 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: KZRJHM+GulliverIT FontSubset: true FirstChar: 31 LastChar: 243 FontDescriptor: FontName: KZRJHM+GulliverIT Flags: Symbolic FontBBox: -137, -211, 945, 816 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HYAXWS+GulliverRM FontSubset: true FirstChar: 31 LastChar: 250 FontDescriptor: FontName: HYAXWS+GulliverRM Flags: Symbolic FontBBox: -79, -211, 1084, 982 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BMIDVL+GulliverSCOsF FontSubset: true FirstChar: 97 LastChar: 117 FontDescriptor: FontName: BMIDVL+GulliverSCOsF Flags: Nonsymbolic, SmallCap FontBBox: 0, -7, 767, 580 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: STLNZV+OneGulliverA FontSubset: true FirstChar: 174 LastChar: 174 FontDescriptor: FontName: STLNZV+OneGulliverA Flags: Symbolic FontBBox: 0, -5, 787, 732 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: SFWDLO+Times-Roman FontSubset: true FirstChar: 32 LastChar: 32 FontDescriptor: FontName: SFWDLO+Times-Roman Flags: FixedPitch, Nonsymbolic, AllCap FontBBox: 0, 0, 1000, 1000 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KVZEWQ+GulliverBL FontSubset: true FirstChar: 46 LastChar: 148 FontDescriptor: FontName: KVZEWQ+GulliverBL Flags: Symbolic FontBBox: -99, -211, 999, 789 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: Elsevier Editorial Ltda. application/pdf Elsevier en 2023-03-27T20:04:06+01:00 Elsevier Editorial Ltda. 2023-03-27T21:05:22+02:00 2023-03-27T20:04:06+01:00 Elsevier 2023-03-27T21:05:22+02:00 http://www.elsevier.es 10.1016/j.opresp.2022.100231 uuid:7ce07cda-c3fe-4f33-93d3-3eebc96b4c9b uuid:6fdf4673-44d0-4542-9c60-57f131716019 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 239, 760, 372, 765 Flags: Print Annotation: Subtype: Link Rect: 272, 677, 366, 682 Flags: Print Annotation: Subtype: Link Rect: 510, 607, 539, 636 Flags: Print Annotation: Subtype: Link Rect: 114, 589, 132, 595 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 121, 589, 139, 595 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 203, 589, 222, 595 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 312, 589, 331, 595 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 440, 589, 459, 595 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 117, 576, 136, 582 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 467, 315, 489, 321 Flags: Print Annotation: Subtype: Link Rect: 489, 315, 552, 321 Flags: Print Annotation: Subtype: Link Rect: 552, 315, 566, 321 Flags: Print Annotation: Subtype: Link Rect: 485, 306, 514, 312 Flags: Print Annotation: Subtype: Link Rect: 514, 306, 526, 312 Flags: Print Annotation: Subtype: Link Rect: 526, 306, 537, 310 Flags: Print Annotation: Subtype: Link Rect: 537, 306, 549, 312 Flags: Print Annotation: Subtype: Link Rect: 549, 306, 555, 311 Flags: Print Annotation: Subtype: Link Rect: 555, 306, 562, 312 Flags: Print Annotation: Subtype: Link Rect: 562, 306, 562, 306 Flags: Print Annotation: Subtype: Link Rect: 104, 95, 164, 100 Flags: Print Annotation: Subtype: Link Rect: 46, 66, 185, 71 Flags: Print Annotation: Subtype: Link Rect: 70, 49, 90, 54 Flags: Print Annotation: Subtype: Link Rect: 90, 49, 146, 54 Flags: Print Annotation: Subtype: Link Rect: 146, 49, 159, 54 Flags: Print Annotation: Subtype: Link Rect: 159, 49, 185, 54 Flags: Print Annotation: Subtype: Link Rect: 185, 49, 195, 54 Flags: Print Annotation: Subtype: Link Rect: 195, 49, 205, 53 Flags: Print Annotation: Subtype: Link Rect: 205, 49, 215, 54 Flags: Print Annotation: Subtype: Link Rect: 215, 49, 221, 54 Flags: Print Annotation: Subtype: Link Rect: 221, 49, 227, 54 Flags: Print Annotation: Subtype: Link Rect: 227, 49, 227, 49 Flags: Print Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 468, 615, 490, 621 Flags: Print Annotation: Subtype: Link Rect: 490, 615, 553, 621 Flags: Print Annotation: Subtype: Link Rect: 553, 615, 567, 621 Flags: Print Annotation: Subtype: Link Rect: 486, 606, 516, 611 Flags: Print Annotation: Subtype: Link Rect: 516, 606, 527, 611 Flags: Print Annotation: Subtype: Link Rect: 527, 606, 538, 610 Flags: Print Annotation: Subtype: Link Rect: 538, 606, 550, 611 Flags: Print Annotation: Subtype: Link Rect: 550, 606, 556, 611 Flags: Print Annotation: Subtype: Link Rect: 556, 606, 563, 611 Flags: Print Annotation: Subtype: Link Rect: 563, 606, 563, 606 Flags: Print Annotation: Subtype: Link Rect: 74, 519, 89, 526 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 153, 466, 162, 474 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 293, 466, 302, 474 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 89, 446, 99, 453 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 91, 372, 100, 380 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 66, 299, 75, 306 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 239, 257, 248, 265 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 242, 194, 251, 202 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 532, 550, 541, 557 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 422, 498, 435, 505 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 474, 477, 487, 484 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 405, 446, 418, 453 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 396, 404, 409, 411 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 433, 383, 445, 390 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 540, 383, 553, 390 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 508, 188, 529, 195 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 512, 178, 525, 185 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 558, 94, 571, 101 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 481, 73, 493, 80 Flags: Print Destination: 1 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 80, 697, 93, 705 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 126, 614, 139, 621 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 98, 446, 123, 452 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 123, 446, 136, 453 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 95, 404, 120, 410 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 120, 404, 133, 412 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 79, 279, 92, 286 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 127, 247, 139, 255 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 100, 195, 112, 202 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 66, 112, 91, 118 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 164, 59, 176, 67 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 315, 739, 336, 746 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 477, 739, 489, 746 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 523, 739, 535, 746 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 342, 728, 354, 736 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 401, 728, 414, 736 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 343, 650, 356, 658 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 372, 541, 384, 548 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 372, 352, 393, 360 Flags: Print Destination: 1 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 141, 486, 152, 491 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 254, 385, 275, 392 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 289, 239, 302, 246 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 258, 228, 280, 236 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 102, 71, 115, 79 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 372, 375, 384, 382 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 339, 258, 363, 265 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 404, 216, 425, 224 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 453, 143, 462, 150 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 334, 91, 355, 98 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 490, 70, 503, 77 Flags: Print Destination: 1 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 153, 440, 163, 445 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 116, 367, 137, 374 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 280, 314, 302, 322 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 66, 220, 88, 228 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 172, 95, 193, 102 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 476, 408, 500, 415 Flags: Print Destination: 1 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 444, 682, 507, 687 Flags: Print Annotation: Subtype: Link Rect: 327, 666, 409, 671 Flags: Print Annotation: Subtype: Link Rect: 327, 657, 346, 663 Annotation: Subtype: Link Rect: 349, 658, 354, 663 Annotation: Subtype: Link Rect: 356, 658, 372, 663 Annotation: Subtype: Link Rect: 374, 658, 380, 663 Annotation: Subtype: Link Rect: 382, 658, 402, 663 Annotation: Subtype: Link Rect: 405, 658, 409, 663 Annotation: Subtype: Link Rect: 412, 658, 437, 663 Annotation: Subtype: Link Rect: 440, 658, 447, 663 Annotation: Subtype: Link Rect: 450, 658, 476, 663 Annotation: Subtype: Link Rect: 477, 657, 481, 663 Annotation: Subtype: Link Rect: 484, 658, 516, 663 Annotation: Subtype: Link Rect: 519, 658, 525, 663 Annotation: Subtype: Link Rect: 527, 658, 566, 663 Annotation: Subtype: Link Rect: 327, 650, 346, 654 Annotation: Subtype: Link Rect: 349, 649, 379, 655 Annotation: Subtype: Link Rect: 381, 650, 403, 655 Annotation: Subtype: Link Rect: 406, 650, 412, 655 Annotation: Subtype: Link Rect: 414, 649, 452, 655 Annotation: Subtype: Link Rect: 455, 650, 466, 655 Annotation: Subtype: Link Rect: 468, 649, 489, 655 Annotation: Subtype: Link Rect: 491, 649, 515, 655 Annotation: Subtype: Link Rect: 518, 650, 533, 655 Annotation: Subtype: Link Rect: 536, 650, 541, 655 Annotation: Subtype: Link Rect: 544, 649, 562, 655 Annotation: Subtype: Link Rect: 564, 649, 566, 655 Annotation: Subtype: Link Rect: 327, 642, 345, 647 Annotation: Subtype: Link Rect: 347, 641, 370, 648 Annotation: Subtype: Link Rect: 373, 642, 384, 648 Annotation: Subtype: Link Rect: 386, 642, 415, 648 Annotation: Subtype: Link Rect: 418, 642, 456, 647 Annotation: Subtype: Link Rect: 457, 644, 460, 644 Annotation: Subtype: Link Rect: 461, 643, 467, 647 Annotation: Subtype: Link Rect: 470, 641, 491, 648 Annotation: Subtype: Link Rect: 493, 641, 527, 648 Annotation: Subtype: Link Rect: 378, 611, 514, 616 Flags: Print Annotation: Subtype: Link Rect: 327, 563, 468, 568 Flags: Print Annotation: Subtype: Link Rect: 425, 523, 544, 528 Flags: Print Annotation: Subtype: Link Rect: 327, 507, 349, 513 Annotation: Subtype: Link Rect: 351, 506, 358, 512 Annotation: Subtype: Link Rect: 360, 506, 408, 512 Annotation: Subtype: Link Rect: 410, 506, 417, 512 Annotation: Subtype: Link Rect: 420, 507, 435, 512 Annotation: Subtype: Link Rect: 437, 506, 442, 512 Annotation: Subtype: Link Rect: 445, 507, 470, 512 Annotation: Subtype: Link Rect: 472, 506, 477, 512 Annotation: Subtype: Link Rect: 479, 506, 507, 512 Annotation: Subtype: Link Rect: 509, 506, 514, 512 Annotation: Subtype: Link Rect: 516, 507, 557, 512 Annotation: Subtype: Link Rect: 559, 506, 566, 512 Annotation: Subtype: Link Rect: 327, 499, 333, 503 Annotation: Subtype: Link Rect: 335, 499, 342, 504 Annotation: Subtype: Link Rect: 345, 499, 380, 504 Annotation: Subtype: Link Rect: 382, 499, 389, 504 Annotation: Subtype: Link Rect: 392, 499, 420, 503 Annotation: Subtype: Link Rect: 423, 499, 430, 504 Annotation: Subtype: Link Rect: 432, 499, 448, 503 Annotation: Subtype: Link Rect: 451, 498, 467, 503 Annotation: Subtype: Link Rect: 470, 499, 477, 503 Annotation: Subtype: Link Rect: 480, 499, 503, 504 Annotation: Subtype: Link Rect: 506, 498, 530, 504 Annotation: Subtype: Link Rect: 532, 499, 546, 504 Annotation: Subtype: Link Rect: 549, 499, 566, 504 Annotation: Subtype: Link Rect: 327, 491, 358, 496 Annotation: Subtype: Link Rect: 360, 490, 404, 496 Annotation: Subtype: Link Rect: 427, 459, 566, 464 Flags: Print Annotation: Subtype: Link Rect: 327, 435, 535, 440 Flags: Print Annotation: Subtype: Link Rect: 327, 411, 550, 416 Flags: Print Annotation: Subtype: Link Rect: 327, 387, 550, 392 Flags: Print Annotation: Subtype: Link Rect: 327, 364, 543, 369 Flags: Print Annotation: Subtype: Link Rect: 327, 356, 472, 361 Flags: Print Annotation: Subtype: Link Rect: 327, 340, 550, 345 Flags: Print Annotation: Subtype: Link Rect: 327, 292, 482, 297 Flags: Print Annotation: Subtype: Link Rect: 327, 252, 488, 257 Flags: Print Annotation: Subtype: Link Rect: 384, 220, 518, 225 Flags: Print Annotation: Subtype: Link Rect: 425, 180, 544, 185 Flags: Print Annotation: Subtype: Link Rect: 327, 140, 476, 145 Flags: Print Annotation: Subtype: Link Rect: 327, 101, 462, 106 Flags: Print Annotation: Subtype: Link Rect: 327, 69, 464, 74 Flags: Print Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 123, 723, 272, 728 Flags: Print Annotation: Subtype: Link Rect: 217, 699, 297, 704 Flags: Print Annotation: Subtype: Link Rect: 57, 691, 118, 696 Flags: Print Annotation: Subtype: Link Rect: 57, 660, 190, 665 Flags: Print Annotation: Subtype: Link Rect: 57, 620, 190, 625 Flags: Print Annotation: Subtype: Link Rect: 159, 588, 297, 593 Flags: Print Annotation: Subtype: Link Rect: 152, 548, 275, 553 Flags: Print Annotation: Subtype: Link Rect: 57, 500, 171, 505 Flags: Print Annotation: Subtype: Link Rect: 123, 468, 256, 473 Flags: Print Annotation: Subtype: Link Rect: 57, 428, 190, 433 Flags: Print Annotation: Subtype: Link Rect: 57, 389, 213, 394 Flags: Print Annotation: Subtype: Link Rect: 164, 357, 297, 362 Flags: Print Annotation: Subtype: Link Rect: 144, 325, 277, 330 Flags: Print Annotation: Subtype: Link Rect: 57, 285, 182, 290 Flags: Print Annotation: Subtype: Link Rect: 327, 739, 457, 744 Flags: Print Annotation: Subtype: Link Rect: 422, 691, 566, 696 Flags: Print Annotation: Subtype: Link Rect: 411, 660, 541, 665 Flags: Print Annotation: Subtype: Link Rect: 422, 612, 566, 617 Flags: Print Annotation: Subtype: Link Rect: 327, 564, 482, 569 Flags: Print Annotation: Subtype: Link Rect: 327, 524, 476, 529 Flags: Print Annotation: Subtype: Link Rect: 327, 484, 471, 489 Flags: Print Annotation: Subtype: Link Rect: 327, 428, 482, 433 Flags: Print Annotation: Subtype: Link Rect: 448, 389, 566, 394 Flags: Print Annotation: Subtype: Link Rect: 327, 373, 369, 378 Annotation: Subtype: Link Rect: 371, 372, 376, 377 Annotation: Subtype: Link Rect: 378, 373, 407, 378 Annotation: Subtype: Link Rect: 409, 372, 419, 377 Annotation: Subtype: Link Rect: 422, 371, 452, 378 Annotation: Subtype: Link Rect: 454, 372, 462, 377 Annotation: Subtype: Link Rect: 464, 373, 470, 377 Annotation: Subtype: Link Rect: 472, 373, 478, 378 Annotation: Subtype: Link Rect: 481, 373, 524, 377 Annotation: Subtype: Link Rect: 527, 371, 566, 378 Annotation: Subtype: Link Rect: 327, 363, 357, 370 Annotation: Subtype: Link Rect: 360, 363, 378, 370 Annotation: Subtype: Link Rect: 381, 365, 392, 370 Annotation: Subtype: Link Rect: 395, 363, 418, 370 Annotation: Subtype: Link Rect: 420, 365, 440, 368 Annotation: Subtype: Link Rect: 443, 363, 466, 370 Annotation: Subtype: Link Rect: 469, 365, 474, 370 Annotation: Subtype: Link Rect: 477, 363, 501, 370 Annotation: Subtype: Link Rect: 504, 365, 518, 370 Annotation: Subtype: Link Rect: 521, 364, 542, 368 Annotation: Subtype: Link Rect: 545, 365, 566, 368 Annotation: Subtype: Link Rect: 327, 357, 347, 362 Annotation: Subtype: Link Rect: 351, 357, 375, 362 Annotation: Subtype: Link Rect: 380, 357, 387, 361 Annotation: Subtype: Link Rect: 392, 357, 422, 362 Annotation: Subtype: Link Rect: 427, 357, 432, 361 Annotation: Subtype: Link Rect: 437, 357, 446, 362 Annotation: Subtype: Link Rect: 451, 355, 480, 361 Annotation: Subtype: Link Rect: 485, 355, 519, 362 Annotation: Subtype: Link Rect: 524, 355, 546, 362 Annotation: Subtype: Link Rect: 550, 355, 566, 362 Annotation: Subtype: Link Rect: 327, 349, 366, 354 Annotation: Subtype: Link Rect: 368, 347, 397, 354 Annotation: Subtype: Link Rect: 399, 349, 415, 354 Annotation: Subtype: Link Rect: 327, 317, 460, 322 Flags: Print Annotation: Subtype: Link Rect: 327, 301, 352, 306 Annotation: Subtype: Link Rect: 354, 301, 368, 306 Annotation: Subtype: Link Rect: 370, 300, 376, 306 Annotation: Subtype: Link Rect: 378, 301, 399, 306 Annotation: Subtype: Link Rect: 400, 300, 404, 306 Annotation: Subtype: Link Rect: 407, 301, 423, 306 Annotation: Subtype: Link Rect: 425, 300, 430, 306 Annotation: Subtype: Link Rect: 433, 301, 438, 305 Annotation: Subtype: Link Rect: 440, 301, 447, 306 Annotation: Subtype: Link Rect: 449, 300, 490, 306 Annotation: Subtype: Link Rect: 492, 300, 515, 306 Annotation: Subtype: Link Rect: 518, 301, 523, 306 Annotation: Subtype: Link Rect: 526, 300, 550, 306 Annotation: Subtype: Link Rect: 552, 301, 566, 306 Annotation: Subtype: Link Rect: 327, 292, 348, 296 Annotation: Subtype: Link Rect: 351, 293, 390, 298 Annotation: Subtype: Link Rect: 393, 293, 415, 298 Annotation: Subtype: Link Rect: 419, 293, 430, 298 Annotation: Subtype: Link Rect: 433, 293, 462, 298 Annotation: Subtype: Link Rect: 465, 293, 481, 298 Annotation: Subtype: Link Rect: 484, 292, 504, 298 Annotation: Subtype: Link Rect: 507, 293, 513, 298 Annotation: Subtype: Link Rect: 516, 293, 555, 298 Annotation: Subtype: Link Rect: 558, 293, 565, 298 Annotation: Subtype: Link Rect: 327, 285, 346, 290 Annotation: Subtype: Link Rect: 349, 284, 379, 290 Annotation: Subtype: Link Rect: 382, 285, 388, 289 Annotation: Subtype: Link Rect: 391, 285, 401, 290 Annotation: Subtype: Link Rect: 404, 284, 433, 290 Annotation: Subtype: Link Rect: 436, 284, 471, 290 Annotation: Subtype: Link Rect: 474, 284, 496, 290 Annotation: Subtype: Link Rect: 499, 284, 516, 290 Annotation: Subtype: Link Rect: 520, 285, 542, 290 Annotation: Subtype: Link Rect: 545, 285, 566, 290 Annotation: Subtype: Link Rect: 327, 277, 343, 282 Checksum: 9dd220a1 Type: CRC32 Checksum: 284bc84e09b5a0a4c1230fb469f76112 Type: MD5 Checksum: d3bd8bc864de807f9555dbca1c308d2f764f45ee Type: SHA-1