e0304afa88855f048d732ba8c8c3e5ae  JPhysMater_a2023v6p022501iENG.pdf
4b8012df28533f0e5010effb9e925dbace173306  JPhysMater_a2023v6p022501iENG.pdf
2880f7e6a10d1b3181b3bfe16896c542476488df54da166c64b6df8dc546124c  JPhysMater_a2023v6p022501iENG.pdf

Title:          Roadmap on nanomedicine for the central nervous system
Subject:        Journal of Physics: Materials, 6 (2023) 022501 doi: 10.1088/2515-7639/acab88
Keywords:       nanomedicines,introductions,central nervous system,roadmap,drug delivery,blood-brain barrier
Author:         Gianni Ciofani,Marco Campisi,Clara Mattu,Roger D Kamm,Valeria Chiono,Aji Alex Moothedathu Raynold,João S Freitas,Eugenio Redolfi Riva,Silvestro Micera,Carlotta Pucci,Fernando Novio,Julia Lorenzo,Daniel Ruiz-Molina,Giulia Sierri,Francesca Re,Hannah Wunderlich,Prachi Kumari,Kristen L Kozielski,Mounia Chami,Attilio Marino,Lino Ferreira,Gianni Ciofani,Marco Campisi,Clara Mattu,Roger D Kamm,Valeria Chiono,Aji Alex Moothedathu Raynold,Gianni Ciofani,João S Freitas,Lino Ferreira,Eugenio Redolfi Riva,Silvestro Micera,Carlotta Pucci,Fernando Novio,Julia Lorenzo,Daniel Ruiz-Molina,Giulia Sierri,Francesca Re,Prachi Kumari,Kristen L Kozielski,Hannah Wunderlich,Mounia Chami,Attilio Marino
Creator:        XeLateX with hyperref package
Producer:       XeLateX; modified using iText® 5.5.13.3 ©2000-2022 iText Group NV (AGPL-version)
CreationDate:   Fri Feb 10 13:28:00 2023 CET
ModDate:        Tue Jan  9 13:59:37 2024 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          40
Encrypted:      no
Page size:      595 x 842 pts (A4)
Page rot:       0
File size:      6682919 bytes
Optimized:      no
PDF version:    1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
Helvetica-Bold                       Type 1            WinAnsi          no  no  no      10  0
AHCPYQ+ArialUnicodeMS                CID TrueType      Identity-H       yes yes yes     11  0
Helvetica                            Type 1            WinAnsi          no  no  no      12  0
ODRDVW+MinionLT-Italic               CID TrueType      Identity-H       yes yes yes     65  0
AWGUGB+MinionLT-Bold                 CID TrueType      Identity-H       yes yes yes     66  0
EGTZLW+MinionLT-Regular              CID TrueType      Identity-H       yes yes yes     67  0
EEFGTY+ITCFranklinGothicStd-BkCd-Identity-H CID Type 0C       Identity-H       yes yes yes    690  0
VVCAKA+ITCFranklinGothicStd-DmCd-Identity-H CID Type 0C       Identity-H       yes yes yes    731  0
TZACYD+MinionLT-Semibold             CID TrueType      Identity-H       yes yes yes    775  0
UPVDKB+CMSY6                         Type 1C           Builtin          yes yes yes    784  0
RSMXHD+Academicons                   CID TrueType      Identity-H       yes yes yes    798  0
PIQHKO+CMR10                         Type 1C           Builtin          yes yes yes    574  0
UKCUDR+CMR8                          Type 1C           Builtin          yes yes yes    501  0
EBUAGD+CMMI10                        Type 1C           Builtin          yes yes yes    675  0
PWFWRG+CMMI8                         Type 1C           Builtin          yes yes yes   1007  0
GOIGKC+CMR7                          Type 1C           Builtin          yes yes yes     94  0
LGQNQE+CMSY10                        Type 1C           Builtin          yes yes yes     68  0
COPLCU+CMSY7                         Type 1C           Builtin          yes yes yes     69  0
APBQFB+EURM10                        Type 1C           Builtin          yes yes yes    797  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-01-20 02:38:06 CET
 RepresentationInformation: JPhysMater_a2023v6p022501iENG.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2024-01-11 01:34:53 CET
  Size: 6682919
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 1363
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: 
    Outlines: 
     Item: 
      Title: Roadmap on nanomedicine for the central nervous system
      Children: 
       Item: 
        Title: 1. Introduction
       Item: 
        Title: 2. Microphysiological systems for preclinical testing of drug-loaded nanoparticle transport across the human blood-brain barrier
       Item: 
        Title: 3. Advanced nanomaterials for ischemic stroke treatment
       Item: 
        Title: 4. Nanotechnology-based neuronal interfaces
       Item: 
        Title: 5. Brain cancer nanomedicine: State of the art and challenges
       Item: 
        Title: 6. Nanoparticles-based developments for Parkinson's disease treatment
       Item: 
        Title: 7. Nanomedicine advances in Alzheimer's disease treatment
       Item: 
        Title: 8. Nanoparticles-mediated deep brain stimulation
       Item: 
        Title: 9. Application of nanotechnologies in the treatment of neuroinflammation in neurodegenerative disorders
       Item: 
        Title: 10.  Nanoparticles-mediated immune therapy for the central nervous system
       Item: 
        Title: References
   Info: 
    Title: Roadmap on nanomedicine for the central nervous system
    Author: Gianni Ciofani,Marco Campisi,Clara Mattu,Roger D Kamm,Valeria Chiono,Aji Alex Moothedathu Raynold,João S Freitas,Eugenio Redolfi Riva,Silvestro Micera,Carlotta Pucci,Fernando Novio,Julia Lorenzo,Daniel Ruiz-Molina,Giulia Sierri,Francesca Re,Hannah Wunderlich,Prachi Kumari,Kristen L Kozielski,Mounia Chami,Attilio Marino,Lino Ferreira,Gianni Ciofani,Marco Campisi,Clara Mattu,Roger D Kamm,Valeria Chiono,Aji Alex Moothedathu Raynold,Gianni Ciofani,João S Freitas,Lino Ferreira,Eugenio Redolfi Riva,Silvestro Micera,Carlotta Pucci,Fernando Novio,Julia Lorenzo,Daniel Ruiz-Molina,Giulia Sierri,Francesca Re,Prachi Kumari,Kristen L Kozielski,Hannah Wunderlich,Mounia Chami,Attilio Marino
    Subject: Journal of Physics: Materials, 6 (2023) 022501 doi: 10.1088/2515-7639/acab88
    Keywords: nanomedicines,introductions,central nervous system,roadmap,drug delivery,blood-brain barrier
    Creator: XeLateX with hyperref package
    Producer: XeLateX; modified using iText® 5.5.13.3 ©2000-2022 iText Group NV (AGPL-version)
    CreationDate: Fri Feb 10 13:28:00 CET 2023
    ModDate: Tue Jan 09 13:59:37 CET 2024
   ID: 0xa984d1d72cf2e07f89786098001b4122, 0xd66dd8d1154453a89b43c10108baf122
   Filters: 
    FilterPipeline: FlateDecode
   Fonts: 
    Type0: 
     Font: 
      BaseFont: ODRDVW+MinionLT-Italic
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: AWGUGB+MinionLT-Bold
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: EEFGTY+ITCFranklinGothicStd-BkCd-Identity-H
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: EGTZLW+MinionLT-Regular
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: TZACYD+MinionLT-Semibold
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: VVCAKA+ITCFranklinGothicStd-DmCd-Identity-H
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: RSMXHD+Academicons
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: UPVDKB+CMSY6
      FontSubset: true
      FirstChar: 0
      LastChar: 3
      FontDescriptor: 
       FontName: UPVDKB+CMSY6
       Flags: Serif, Symbolic, Italic
       FontBBox: -4, -948, 1329, 786
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: EBUAGD+CMMI10
      FontSubset: true
      FirstChar: 11
      LastChar: 60
      FontDescriptor: 
       FontName: EBUAGD+CMMI10
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: LGQNQE+CMSY10
      FontSubset: true
      FirstChar: 6
      LastChar: 15
      FontDescriptor: 
       FontName: LGQNQE+CMSY10
       Flags: Serif, Symbolic, Italic
       FontBBox: -29, -960, 1116, 775
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: UKCUDR+CMR8
      FontSubset: true
      FirstChar: 18
      LastChar: 126
      FontDescriptor: 
       FontName: UKCUDR+CMR8
       Flags: Serif, Symbolic
       FontBBox: -36, -250, 1070, 750
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: COPLCU+CMSY7
      FontSubset: true
      FirstChar: 0
      LastChar: 0
      FontDescriptor: 
       FontName: COPLCU+CMSY7
       Flags: Serif, Symbolic, Italic
       FontBBox: -15, -951, 1251, 782
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: APBQFB+EURM10
      FontSubset: true
      FirstChar: 12
      LastChar: 12
      FontDescriptor: 
       FontName: APBQFB+EURM10
       Flags: Serif, Symbolic
       FontBBox: -32, -243, 1060, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: PIQHKO+CMR10
      FontSubset: true
      FirstChar: 18
      LastChar: 126
      FontDescriptor: 
       FontName: PIQHKO+CMR10
       Flags: Serif, Symbolic
       FontBBox: -40, -250, 1009, 750
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: GOIGKC+CMR7
      FontSubset: true
      FirstChar: 43
      LastChar: 43
      FontDescriptor: 
       FontName: GOIGKC+CMR7
       Flags: Serif, Symbolic
       FontBBox: -27, -250, 1122, 750
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: PWFWRG+CMMI8
      FontSubset: true
      FirstChar: 22
      LastChar: 22
      FontDescriptor: 
       FontName: PWFWRG+CMMI8
       Flags: Serif, Symbolic, Italic
       FontBBox: -24, -250, 1110, 750
       FontFile3: true
      ToUnicode: true
    CIDFontType0: 
     Font: 
      BaseFont: EEFGTY+ITCFranklinGothicStd-BkCd
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: EEFGTY+ITCFranklinGothicStd-BkCd
       Flags: Serif, Symbolic
       FontBBox: -162, -250, 940, 893
       FontFile3: true
     Font: 
      BaseFont: VVCAKA+ITCFranklinGothicStd-DmCd
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: VVCAKA+ITCFranklinGothicStd-DmCd
       Flags: Serif, Symbolic, ForceBold
       FontBBox: -141, -250, 941, 903
       FontFile3: true
    CIDFontType2: 
     Font: 
      BaseFont: EGTZLW+MinionLT-Regular
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: EGTZLW+MinionLT-Regular
       Flags: Serif, Symbolic
       FontBBox: -141, -250, 1104, 812
       FontFile2: true
     Font: 
      BaseFont: TZACYD+MinionLT-Semibold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: TZACYD+MinionLT-Semibold
       Flags: Serif, Symbolic, ForceBold
       FontBBox: -146, -250, 1126, 830
       FontFile2: true
     Font: 
      BaseFont: ODRDVW+MinionLT-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: ODRDVW+MinionLT-Italic
       Flags: Serif, Symbolic, Italic
       FontBBox: -139, -250, 1103, 812
       FontFile2: true
     Font: 
      BaseFont: RSMXHD+Academicons
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: RSMXHD+Academicons
       Flags: Serif, Symbolic
       FontBBox: 0, -81, 999, 793
       FontFile2: true
     Font: 
      BaseFont: AWGUGB+MinionLT-Bold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AWGUGB+MinionLT-Bold
       Flags: Serif, Symbolic
       FontBBox: -148, -250, 1147, 830
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.1.0-jc003">
  <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
    <rdf:Description rdf:about=""
        xmlns:xmp="http://ns.adobe.com/xap/1.0/"
        xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
        xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
        xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#"
        xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
        xmlns:dc="http://purl.org/dc/elements/1.1/"
        xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
        xmlns:prism_1_="http://prismstandard.org/namespaces/basic/2.1/"
        xmlns:crossmark="http://crossref.org/crossmark/1.0/"
        xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
        xmlns:jav="http://www.niso.org/schemas/jav/1.0/"
        xmlns:ali="http://www.niso.org/schemas/ali/1.0/"
      xmp:CreateDate="2023-02-10T12:28Z"
      xmp:ModifyDate="2024-01-09T12:59:37Z"
      xmp:MetadataDate="2024-01-09T12:59:37Z"
      xmp:CreatorTool="XeLateX with hyperref package"
      pdf:Keywords="nanomedicines,introductions,central nervous system,roadmap,drug delivery,blood-brain barrier"
      pdf:Producer="XeLateX; modified using iText® 5.5.13.3 ©2000-2022 iText Group NV (AGPL-version)"
      dc:format="application/pdf"
      dc:identifier="https://doi.org/10.1088/2515-7639/acab88"
      xmpMM:DocumentID="uuid:d1dc959b-b675-4954-8418-88d7a33ea8dc"
      xmpMM:InstanceID="uuid:20546cef-26c9-4005-8c46-7f2bb62b1333"
      prism_1_:publicationName="Journal of Physics: Materials"
      prism_1_:aggregationType="journal"
      prism_1_:volume="6"
      prism_1_:number="2"
      prism_1_:pageRange="022501"
      prism_1_:issn="2515-7639"
      prism_1_:startingPage="1"
      prism_1_:endingPage="39"
      prism_1_:doi="10.1088/2515-7639/acab88"
      prism_1_:url="https://doi.org/10.1088/2515-7639/acab88"
      crossmark:MajorVersionDate="2023-2-14"
      crossmark:CrossmarkDomainExclusive="true"
      crossmark:DOI="10.1088/2515-7639/acab88"
      pdfx:doi="10.1088/2515-7639/acab88"
      pdfx:robots="noindex"
      pdfx:CrossMarkMajorVersionDate="2023-2-14"
      pdfx:CrossmarkDomainExclusive="true"
      jav:journal_article_version="VoR"
      ali:license_ref="http://iopscience.iop.org/page/copyright">
      <pdfaExtension:schemas>
        <rdf:Bag>
          <rdf:li>
            <rdf:Description
              pdfaSchema:schema="XMP Media Management Schema"
              pdfaSchema:prefix="xmpMM"
              pdfaSchema:namespaceURI="http://ns.adobe.com/xap/1.0/mm/">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:name="DocumentID"
                  pdfaProperty:valueType="URI"
                  pdfaProperty:category="internal"
                  pdfaProperty:description="UUID based identifier for all versions and renditions of a document"/>
                <rdf:li
                  pdfaProperty:name="InstanceID"
                  pdfaProperty:valueType="URI"
                  pdfaProperty:category="internal"
                  pdfaProperty:description="UUID based identifier for specific incarnation of a document"/>
                <rdf:li
                  pdfaProperty:name="VersionID"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Document version identifier"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:schema="PRISM Basic Metadata"
              pdfaSchema:prefix="prism"
              pdfaSchema:namespaceURI="http://prismstandard.org/namespaces/basic/2.1/">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:name="complianceProfile"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="internal"
                  pdfaProperty:description="PRISM specification compliance profile to which this document adheres"/>
                <rdf:li
                  pdfaProperty:name="publicationName"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Publication name"/>
                <rdf:li
                  pdfaProperty:name="aggregationType"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Publication type"/>
                <rdf:li
                  pdfaProperty:name="bookEdition"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Edition of the book in which the document was published"/>
                <rdf:li
                  pdfaProperty:name="volume"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Publication volume number"/>
                <rdf:li
                  pdfaProperty:name="number"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Publication issue number within a volume"/>
                <rdf:li
                  pdfaProperty:name="pageRange"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Page range for the document within the print version of its publication"/>
                <rdf:li
                  pdfaProperty:name="issn"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="ISSN for the printed publication in which the document was published"/>
                <rdf:li
                  pdfaProperty:name="eIssn"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="ISSN for the electronic publication in which the document was published"/>
                <rdf:li
                  pdfaProperty:name="isbn"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="ISBN for the publication in which the document was published"/>
                <rdf:li
                  pdfaProperty:name="doi"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Digital Object Identifier for the document"/>
                <rdf:li
                  pdfaProperty:name="url"
                  pdfaProperty:valueType="URL"
                  pdfaProperty:category="external"
                  pdfaProperty:description="URL at which the document can be found"/>
                <rdf:li
                  pdfaProperty:name="byteCount"
                  pdfaProperty:valueType="Integer"
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Approximate file size in octets"/>
                <rdf:li
                  pdfaProperty:name="pageCount"
                  pdfaProperty:valueType="Integer"
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Number of pages in the print version of the document"/>
                <rdf:li
                  pdfaProperty:name="subtitle"
                  pdfaProperty:valueType="Text"
                  pdfaProperty:category="external"
                  pdfaProperty:description="Document's subtitle"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
        </rdf:Bag>
      </pdfaExtension:schemas>
      <dc:publisher>
        <rdf:Bag>
          <rdf:li>IOP Publishing</rdf:li>
        </rdf:Bag>
      </dc:publisher>
      <dc:date>
        <rdf:Seq>
          <rdf:li>2023-02-10T12:28</rdf:li>
        </rdf:Seq>
      </dc:date>
      <dc:language>
        <rdf:Bag>
          <rdf:li/>
        </rdf:Bag>
      </dc:language>
      <dc:type>
        <rdf:Bag>
          <rdf:li>Text</rdf:li>
        </rdf:Bag>
      </dc:type>
      <dc:description>
        <rdf:Alt>
          <rdf:li xml:lang="x-default">Journal of Physics: Materials, 6 (2023) 022501 doi: 10.1088/2515-7639/acab88</rdf:li>
        </rdf:Alt>
      </dc:description>
      <dc:subject>
        <rdf:Bag>
          <rdf:li>nanomedicines</rdf:li>
          <rdf:li>introductions</rdf:li>
          <rdf:li>central nervous system</rdf:li>
          <rdf:li>roadmap</rdf:li>
          <rdf:li>drug delivery</rdf:li>
          <rdf:li>blood-brain barrier</rdf:li>
        </rdf:Bag>
      </dc:subject>
      <dc:title>
        <rdf:Alt>
          <rdf:li xml:lang="x-default">Roadmap on nanomedicine for the central nervous system</rdf:li>
        </rdf:Alt>
      </dc:title>
      <dc:creator>
        <rdf:Seq>
          <rdf:li>Gianni Ciofani,Marco Campisi,Clara Mattu,Roger D Kamm,Valeria Chiono,Aji Alex Moothedathu Raynold,João S Freitas,Eugenio Redolfi Riva,Silvestro Micera,Carlotta Pucci,Fernando Novio,Julia Lorenzo,Daniel Ruiz-Molina,Giulia Sierri,Francesca Re,Hannah Wunderlich,Prachi Kumari,Kristen L Kozielski,Mounia Chami,Attilio Marino,Lino Ferreira,Gianni Ciofani,Marco Campisi,Clara Mattu,Roger D Kamm,Valeria Chiono,Aji Alex Moothedathu Raynold,Gianni Ciofani,João S Freitas,Lino Ferreira,Eugenio Redolfi Riva,Silvestro Micera,Carlotta Pucci,Fernando Novio,Julia Lorenzo,Daniel Ruiz-Molina,Giulia Sierri,Francesca Re,Prachi Kumari,Kristen L Kozielski,Hannah Wunderlich,Mounia Chami,Attilio Marino</rdf:li>
        </rdf:Seq>
      </dc:creator>
      <crossmark:CrossMarkDomains>
        <rdf:Seq>
          <rdf:li>iop.org</rdf:li>
        </rdf:Seq>
      </crossmark:CrossMarkDomains>
      <pdfx:CrossMarkDomains>
        <rdf:Seq>
          <rdf:li>iop.org</rdf:li>
        </rdf:Seq>
      </pdfx:CrossMarkDomains>
    </rdf:Description>
  </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 71, 600, 116, 607
      Annotation: 
       Subtype: Link
       Rect: 422, 700, 543, 706
      Annotation: 
       Subtype: Link
       Rect: 422, 692, 549, 698
      Annotation: 
       Subtype: Link
       Rect: 422, 684, 482, 690
      Annotation: 
       Subtype: Link
       Rect: 422, 652, 499, 659
      Annotation: 
       Subtype: Link
       Rect: 422, 621, 518, 627
      Annotation: 
       Subtype: Link
       Rect: 37, 51, 557, 190
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 417, 797, 552, 806
      Annotation: 
       Subtype: Link
       Rect: 42, 704, 97, 724
      Annotation: 
       Subtype: Link
       Rect: 42, 538, 95, 545
      Annotation: 
       Subtype: Link
       Rect: 42, 530, 103, 537
      Annotation: 
       Subtype: Link
       Rect: 179, 671, 182, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 183, 671, 189, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 190, 673, 194, 676
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 194, 668, 204, 678
      Annotation: 
       Subtype: Link
       Rect: 271, 671, 273, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 275, 671, 278, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 279, 671, 282, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 336, 671, 339, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 340, 671, 343, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 411, 671, 413, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 415, 671, 418, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 418, 668, 428, 678
      Annotation: 
       Subtype: Link
       Rect: 493, 671, 496, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 497, 671, 500, 678
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 500, 668, 510, 678
      Annotation: 
       Subtype: Link
       Rect: 245, 659, 248, 666
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 307, 659, 310, 666
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 400, 659, 402, 666
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 472, 659, 475, 666
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 476, 659, 482, 666
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 544, 659, 547, 666
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 185, 647, 191, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 192, 647, 198, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 256, 647, 262, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 263, 647, 269, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 269, 644, 279, 654
      Annotation: 
       Subtype: Link
       Rect: 364, 647, 369, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 369, 644, 379, 654
      Annotation: 
       Subtype: Link
       Rect: 434, 647, 439, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 496, 647, 502, 654
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 202, 635, 207, 642
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 271, 635, 277, 642
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 358, 635, 363, 642
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 363, 632, 373, 642
      Annotation: 
       Subtype: Link
       Rect: 440, 635, 445, 642
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 445, 632, 455, 642
      Annotation: 
       Subtype: Link
       Rect: 519, 635, 521, 642
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 189, 623, 192, 630
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 194, 623, 196, 630
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 196, 620, 206, 630
      Annotation: 
       Subtype: Link
       Rect: 144, 391, 211, 400
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 119, 745, 183, 755
       ActionDest: 1062
      Annotation: 
       Subtype: Link
       Rect: 547, 745, 552, 755
       ActionDest: 1062
      Annotation: 
       Subtype: Link
       Rect: 119, 732, 523, 743
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 131, 720, 240, 730
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 547, 720, 552, 730
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 119, 707, 349, 718
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 543, 707, 552, 718
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 119, 695, 302, 705
       ActionDest: 562
      Annotation: 
       Subtype: Link
       Rect: 543, 695, 552, 705
       ActionDest: 562
      Annotation: 
       Subtype: Link
       Rect: 119, 682, 364, 693
       ActionDest: 897
      Annotation: 
       Subtype: Link
       Rect: 543, 682, 552, 693
       ActionDest: 897
      Annotation: 
       Subtype: Link
       Rect: 119, 670, 404, 680
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 543, 670, 552, 680
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 119, 657, 359, 668
       ActionDest: 1135
      Annotation: 
       Subtype: Link
       Rect: 543, 657, 552, 668
       ActionDest: 1135
      Annotation: 
       Subtype: Link
       Rect: 119, 645, 321, 655
       ActionDest: 937
      Annotation: 
       Subtype: Link
       Rect: 543, 645, 552, 655
       ActionDest: 937
      Annotation: 
       Subtype: Link
       Rect: 119, 632, 506, 643
       ActionDest: 602
      Annotation: 
       Subtype: Link
       Rect: 131, 620, 168, 630
       ActionDest: 602
      Annotation: 
       Subtype: Link
       Rect: 543, 620, 552, 630
       ActionDest: 602
      Annotation: 
       Subtype: Link
       Rect: 119, 607, 419, 618
       ActionDest: 62
      Annotation: 
       Subtype: Link
       Rect: 543, 607, 552, 618
       ActionDest: 62
      Annotation: 
       Subtype: Link
       Rect: 119, 595, 225, 605
       ActionDest: 112
      Annotation: 
       Subtype: Link
       Rect: 543, 595, 552, 605
       ActionDest: 112
      Annotation: 
       Subtype: Link
       Rect: 119, 582, 161, 593
       ActionDest: 112
      Annotation: 
       Subtype: Link
       Rect: 543, 582, 552, 593
       ActionDest: 112
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 420, 657, 425, 668
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 500, 595, 505, 605
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 526, 532, 531, 543
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 122, 482, 127, 493
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 270, 432, 275, 443
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 396, 370, 401, 380
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 299, 295, 304, 305
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 281, 257, 286, 268
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 161, 220, 166, 230
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 480, 169, 485, 180
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 303, 132, 308, 142
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 365, 119, 370, 130
       ActionDest: 562
      Annotation: 
       Subtype: Link
       Rect: 211, 94, 216, 105
       ActionDest: 897
      Annotation: 
       Subtype: Link
       Rect: 439, 82, 444, 92
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 463, 82, 468, 92
       ActionDest: 1135
      Annotation: 
       Subtype: Link
       Rect: 150, 44, 155, 55
       ActionDest: 937
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 353, 757, 358, 768
       ActionDest: 602
      Annotation: 
       Subtype: Link
       Rect: 190, 720, 200, 730
       ActionDest: 62
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 178, 737, 182, 746
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 184, 737, 188, 746
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 190, 737, 193, 746
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 247, 737, 251, 746
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 253, 737, 256, 746
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 321, 737, 325, 746
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 327, 737, 331, 746
       ActionDest: 1111
      Annotation: 
       Subtype: Link
       Rect: 409, 737, 413, 746
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 415, 737, 418, 746
       ActionDest: 50
      Annotation: 
       Subtype: Link
       Rect: 404, 595, 413, 605
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 347, 570, 351, 580
       ActionDest: 1273
      Annotation: 
       Subtype: Link
       Rect: 348, 545, 357, 555
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 151, 482, 160, 493
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 122, 445, 132, 455
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 447, 395, 456, 405
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 435, 357, 445, 368
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 450, 357, 459, 368
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 510, 332, 520, 343
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 525, 332, 534, 343
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 381, 231, 391, 242
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 307, 181, 317, 192
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 322, 181, 331, 192
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 384, 156, 393, 167
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 409, 81, 419, 92
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 457, 81, 462, 92
       ActionDest: 1273
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 379, 388, 387, 396
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 469, 388, 516, 396
      Annotation: 
       Subtype: Link
       Rect: 344, 344, 354, 355
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 517, 294, 527, 305
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 323, 219, 333, 229
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 535, 206, 544, 217
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 537, 156, 546, 167
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 260, 119, 269, 129
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 431, 56, 441, 67
       ActionDest: 113
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 452, 99, 460, 107
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 187, 90, 195, 98
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 307, 90, 356, 98
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 298, 443, 345, 451
      Annotation: 
       Subtype: Link
       Rect: 502, 334, 512, 344
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 517, 334, 526, 344
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 257, 309, 267, 319
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 272, 309, 282, 319
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 287, 296, 292, 307
       ActionDest: 1273
      Annotation: 
       Subtype: Link
       Rect: 430, 234, 439, 244
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 478, 234, 483, 244
       ActionDest: 1296
      Annotation: 
       Subtype: Link
       Rect: 193, 168, 203, 178
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 336, 143, 346, 153
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 351, 143, 360, 153
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 277, 118, 282, 128
       ActionDest: 1296
      Annotation: 
       Subtype: Link
       Rect: 313, 118, 318, 128
       ActionDest: 1297
      Annotation: 
       Subtype: Link
       Rect: 198, 80, 208, 91
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 213, 80, 223, 91
       ActionDest: 113
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 186, 745, 195, 755
       ActionDest: 113
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 239, 750, 243, 758
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 306, 750, 310, 758
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 367, 750, 370, 758
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 441, 750, 444, 758
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 446, 750, 450, 758
       ActionDest: 73
      Annotation: 
       Subtype: Link
       Rect: 173, 632, 183, 643
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 251, 607, 261, 618
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 210, 582, 215, 593
       ActionDest: 222
      Annotation: 
       Subtype: Link
       Rect: 455, 570, 465, 580
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 201, 532, 210, 543
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 215, 532, 225, 543
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 400, 495, 410, 505
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 415, 495, 424, 505
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 469, 405, 479, 416
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 483, 405, 493, 416
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 495, 380, 504, 391
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 466, 355, 476, 366
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 189, 293, 198, 303
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 175, 280, 185, 291
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 251, 280, 260, 291
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 349, 280, 359, 291
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 526, 230, 536, 241
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 413, 180, 423, 191
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 513, 118, 522, 128
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 493, 80, 502, 91
       ActionDest: 218
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 453, 82, 458, 92
       ActionDest: 222
      Annotation: 
       Subtype: Link
       Rect: 203, 44, 212, 55
       ActionDest: 218
    Page: 
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 521, 770, 530, 780
       ActionDest: 113
      Annotation: 
       Subtype: Link
       Rect: 535, 770, 545, 780
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 229, 745, 239, 755
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 488, 745, 498, 755
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 203, 732, 213, 743
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 309, 720, 318, 730
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 315, 707, 325, 718
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 523, 682, 533, 693
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 300, 620, 310, 630
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 249, 582, 259, 593
       ActionDest: 113
    Page: 
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 199, 750, 203, 758
       ActionDest: 562
      Annotation: 
       Subtype: Link
       Rect: 284, 750, 288, 758
       ActionDest: 562
      Annotation: 
       Subtype: Link
       Rect: 289, 750, 293, 758
       ActionDest: 562
      Annotation: 
       Subtype: Link
       Rect: 223, 620, 232, 630
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 380, 545, 390, 555
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 395, 545, 404, 555
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 218, 307, 223, 317
       ActionDest: 595
      Annotation: 
       Subtype: Link
       Rect: 398, 244, 408, 255
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 465, 194, 474, 205
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 479, 194, 488, 205
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 420, 119, 429, 130
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 434, 119, 444, 130
       ActionDest: 218
    Page: 
     Sequence: 15
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 246, 502, 253, 510
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 150, 493, 157, 501
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 150, 484, 157, 492
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 499, 484, 507, 492
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 247, 466, 255, 474
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 223, 457, 230, 465
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 150, 448, 157, 456
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 468, 448, 476, 456
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 320, 430, 328, 438
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 394, 421, 402, 429
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 445, 269, 455, 280
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 493, 244, 498, 255
       ActionDest: 653
      Annotation: 
       Subtype: Link
       Rect: 419, 194, 428, 205
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 268, 132, 278, 142
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 278, 82, 288, 92
       ActionDest: 218
    Page: 
     Sequence: 16
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 210, 522, 218, 530
       ActionDest: 218
    Page: 
     Sequence: 17
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 234, 670, 244, 680
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 490, 645, 499, 655
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 305, 620, 315, 630
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 351, 607, 360, 618
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 267, 445, 277, 455
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 153, 319, 162, 330
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 514, 307, 524, 317
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 245, 269, 255, 280
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 260, 269, 269, 280
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 369, 207, 379, 217
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 236, 182, 245, 192
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 308, 144, 318, 155
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 298, 107, 308, 117
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 517, 69, 526, 80
       ActionDest: 219
    Page: 
     Sequence: 18
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 373, 670, 382, 681
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 231, 620, 240, 631
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 148, 508, 153, 518
       ActionDest: 739
      Annotation: 
       Subtype: Link
       Rect: 162, 508, 172, 518
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 361, 458, 371, 468
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 311, 408, 315, 418
       ActionDest: 752
      Annotation: 
       Subtype: Link
       Rect: 325, 408, 335, 418
       ActionDest: 219
    Page: 
     Sequence: 19
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 386, 175, 394, 184
       ActionDest: 219
    Page: 
     Sequence: 20
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 435, 530, 442, 539
       ActionDest: 219
    Page: 
     Sequence: 21
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 181, 750, 185, 758
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 187, 750, 191, 758
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 247, 750, 251, 758
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 252, 750, 256, 758
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 354, 750, 358, 758
       ActionDest: 757
      Annotation: 
       Subtype: Link
       Rect: 196, 570, 206, 580
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 500, 457, 510, 468
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 272, 420, 282, 430
       ActionDest: 795
      Annotation: 
       Subtype: Link
       Rect: 459, 332, 468, 343
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 246, 307, 256, 318
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 141, 295, 151, 305
       ActionDest: 219
    Page: 
     Sequence: 22
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 431, 304, 441, 314
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 407, 279, 416, 289
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 366, 254, 376, 264
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 180, 182, 189, 192
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 351, 82, 360, 92
       ActionDest: 846
    Page: 
     Sequence: 23
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 149, 439, 158, 449
       ActionDest: 219
    Page: 
     Sequence: 24
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 176, 682, 185, 693
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 462, 670, 471, 680
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 217, 595, 227, 605
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 232, 595, 241, 605
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 401, 370, 411, 380
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 406, 345, 415, 355
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 201, 206, 211, 217
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 427, 194, 437, 204
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 439, 156, 454, 167
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 487, 144, 496, 154
       ActionDest: 893
      Annotation: 
       Subtype: Link
       Rect: 427, 56, 437, 67
       ActionDest: 896
    Page: 
     Sequence: 25
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 377, 288, 391, 299
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 398, 251, 413, 262
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 415, 198, 430, 208
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 398, 173, 408, 183
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 213, 148, 227, 158
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 508, 107, 522, 117
       ActionDest: 219
    Page: 
     Sequence: 26
    Page: 
     Sequence: 27
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 176, 750, 180, 758
       ActionDest: 937
      Annotation: 
       Subtype: Link
       Rect: 256, 750, 259, 758
       ActionDest: 937
      Annotation: 
       Subtype: Link
       Rect: 359, 750, 363, 758
       ActionDest: 937
      Annotation: 
       Subtype: Link
       Rect: 122, 519, 137, 529
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 450, 506, 464, 517
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 469, 506, 483, 517
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 281, 419, 295, 429
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 268, 406, 282, 417
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 329, 369, 339, 379
       ActionDest: 92
      Annotation: 
       Subtype: Link
       Rect: 190, 344, 204, 354
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 343, 281, 352, 292
       ActionDest: 92
      Annotation: 
       Subtype: Link
       Rect: 406, 281, 420, 292
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 273, 181, 288, 192
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 122, 144, 132, 154
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 137, 144, 151, 154
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 450, 131, 464, 142
       ActionDest: 220
    Page: 
     Sequence: 28
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 226, 398, 238, 407
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 241, 398, 253, 407
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 257, 398, 268, 407
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 272, 398, 283, 407
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 287, 398, 299, 407
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 384, 244, 393, 255
       ActionDest: 92
      Annotation: 
       Subtype: Link
       Rect: 471, 232, 486, 242
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 472, 157, 481, 167
       ActionDest: 92
      Annotation: 
       Subtype: Link
       Rect: 503, 157, 517, 167
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 414, 132, 428, 142
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 288, 44, 298, 55
       ActionDest: 218
    Page: 
     Sequence: 29
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 169, 444, 177, 452
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 181, 444, 192, 452
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 236, 332, 246, 342
       ActionDest: 484
      Annotation: 
       Subtype: Link
       Rect: 300, 332, 309, 342
       ActionDest: 218
      Annotation: 
       Subtype: Link
       Rect: 459, 319, 473, 330
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 434, 257, 444, 267
       ActionDest: 484
      Annotation: 
       Subtype: Link
       Rect: 498, 257, 512, 267
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 362, 244, 376, 255
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 428, 194, 442, 205
       ActionDest: 219
      Annotation: 
       Subtype: Link
       Rect: 447, 194, 461, 205
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 466, 194, 481, 205
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 486, 194, 500, 205
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 505, 194, 519, 205
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 295, 132, 304, 142
       ActionDest: 92
      Annotation: 
       Subtype: Link
       Rect: 357, 132, 371, 142
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 202, 44, 216, 55
       ActionDest: 220
    Page: 
     Sequence: 30
    Page: 
     Sequence: 31
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 430, 657, 444, 668
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 365, 607, 379, 618
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 261, 582, 271, 593
       ActionDest: 678
      Annotation: 
       Subtype: Link
       Rect: 405, 495, 420, 505
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 205, 470, 219, 480
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 512, 319, 522, 330
       ActionDest: 678
      Annotation: 
       Subtype: Link
       Rect: 490, 282, 504, 292
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 509, 282, 523, 292
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 317, 244, 332, 255
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 487, 219, 502, 230
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 371, 194, 385, 205
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 390, 194, 404, 205
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 317, 169, 331, 180
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 336, 169, 350, 180
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 486, 69, 501, 80
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 388, 44, 402, 55
       ActionDest: 220
    Page: 
     Sequence: 32
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 295, 360, 309, 370
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 478, 322, 493, 333
       ActionDest: 220
    Page: 
     Sequence: 33
    Page: 
     Sequence: 34
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 334, 620, 348, 630
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 237, 595, 251, 605
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 263, 532, 278, 543
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 221, 507, 230, 518
       ActionDest: 63
      Annotation: 
       Subtype: Link
       Rect: 240, 507, 254, 518
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 459, 345, 473, 355
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 419, 320, 434, 330
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 122, 207, 137, 218
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 400, 157, 414, 168
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 264, 120, 279, 130
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 450, 107, 465, 118
       ActionDest: 220
    Page: 
     Sequence: 35
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 343, 516, 355, 525
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 122, 459, 137, 470
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 427, 371, 441, 382
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 311, 346, 326, 357
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 303, 271, 313, 282
       ActionDest: 112
      Annotation: 
       Subtype: Link
       Rect: 322, 271, 337, 282
       ActionDest: 220
    Page: 
     Sequence: 36
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 504, 375, 516, 383
       ActionDest: 220
      Annotation: 
       Subtype: Link
       Rect: 180, 151, 188, 159
      Annotation: 
       Subtype: Link
       Rect: 191, 149, 347, 160
      Annotation: 
       Subtype: Link
       Rect: 184, 138, 192, 146
      Annotation: 
       Subtype: Link
       Rect: 194, 137, 352, 148
      Annotation: 
       Subtype: Link
       Rect: 181, 126, 189, 134
      Annotation: 
       Subtype: Link
       Rect: 191, 124, 348, 135
      Annotation: 
       Subtype: Link
       Rect: 174, 113, 182, 121
      Annotation: 
       Subtype: Link
       Rect: 184, 112, 341, 123
      Annotation: 
       Subtype: Link
       Rect: 200, 101, 208, 109
      Annotation: 
       Subtype: Link
       Rect: 211, 99, 367, 110
      Annotation: 
       Subtype: Link
       Rect: 196, 88, 204, 96
      Annotation: 
       Subtype: Link
       Rect: 206, 87, 363, 98
      Annotation: 
       Subtype: Link
       Rect: 182, 76, 190, 84
      Annotation: 
       Subtype: Link
       Rect: 192, 74, 349, 85
      Annotation: 
       Subtype: Link
       Rect: 173, 63, 181, 71
      Annotation: 
       Subtype: Link
       Rect: 183, 62, 340, 73
    Page: 
     Sequence: 37
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 197, 738, 204, 746
      Annotation: 
       Subtype: Link
       Rect: 206, 738, 229, 746
      Annotation: 
       Subtype: Link
       Rect: 234, 718, 242, 726
      Annotation: 
       Subtype: Link
       Rect: 244, 718, 252, 726
      Annotation: 
       Subtype: Link
       Rect: 232, 698, 240, 706
      Annotation: 
       Subtype: Link
       Rect: 241, 698, 276, 706
      Annotation: 
       Subtype: Link
       Rect: 182, 678, 186, 686
      Annotation: 
       Subtype: Link
       Rect: 188, 678, 211, 686
      Annotation: 
       Subtype: Link
       Rect: 354, 658, 358, 666
      Annotation: 
       Subtype: Link
       Rect: 360, 658, 387, 666
      Annotation: 
       Subtype: Link
       Rect: 392, 638, 400, 646
      Annotation: 
       Subtype: Link
       Rect: 402, 638, 425, 646
      Annotation: 
       Subtype: Link
       Rect: 212, 588, 220, 596
      Annotation: 
       Subtype: Link
       Rect: 222, 588, 245, 596
      Annotation: 
       Subtype: Link
       Rect: 287, 568, 295, 576
      Annotation: 
       Subtype: Link
       Rect: 297, 568, 320, 576
      Annotation: 
       Subtype: Link
       Rect: 140, 548, 144, 556
      Annotation: 
       Subtype: Link
       Rect: 146, 548, 165, 556
      Annotation: 
       Subtype: Link
       Rect: 492, 538, 499, 546
      Annotation: 
       Subtype: Link
       Rect: 501, 538, 517, 546
      Annotation: 
       Subtype: Link
       Rect: 351, 518, 355, 526
      Annotation: 
       Subtype: Link
       Rect: 356, 518, 380, 526
      Annotation: 
       Subtype: Link
       Rect: 273, 498, 281, 506
      Annotation: 
       Subtype: Link
       Rect: 283, 498, 310, 506
      Annotation: 
       Subtype: Link
       Rect: 505, 488, 513, 496
      Annotation: 
       Subtype: Link
       Rect: 515, 488, 538, 496
      Annotation: 
       Subtype: Link
       Rect: 421, 478, 429, 486
      Annotation: 
       Subtype: Link
       Rect: 431, 478, 454, 486
      Annotation: 
       Subtype: Link
       Rect: 208, 458, 216, 466
      Annotation: 
       Subtype: Link
       Rect: 218, 458, 237, 466
      Annotation: 
       Subtype: Link
       Rect: 296, 438, 308, 446
      Annotation: 
       Subtype: Link
       Rect: 310, 438, 333, 446
      Annotation: 
       Subtype: Link
       Rect: 198, 418, 202, 426
      Annotation: 
       Subtype: Link
       Rect: 204, 418, 219, 426
      Annotation: 
       Subtype: Link
       Rect: 233, 398, 236, 406
      Annotation: 
       Subtype: Link
       Rect: 238, 398, 258, 406
      Annotation: 
       Subtype: Link
       Rect: 256, 378, 264, 386
      Annotation: 
       Subtype: Link
       Rect: 266, 378, 293, 386
      Annotation: 
       Subtype: Link
       Rect: 254, 358, 266, 366
      Annotation: 
       Subtype: Link
       Rect: 267, 358, 290, 366
      Annotation: 
       Subtype: Link
       Rect: 329, 338, 337, 346
      Annotation: 
       Subtype: Link
       Rect: 339, 338, 366, 346
      Annotation: 
       Subtype: Link
       Rect: 322, 318, 334, 326
      Annotation: 
       Subtype: Link
       Rect: 336, 318, 359, 326
      Annotation: 
       Subtype: Link
       Rect: 246, 298, 253, 306
      Annotation: 
       Subtype: Link
       Rect: 255, 298, 275, 306
      Annotation: 
       Subtype: Link
       Rect: 329, 278, 337, 286
      Annotation: 
       Subtype: Link
       Rect: 339, 278, 354, 286
      Annotation: 
       Subtype: Link
       Rect: 164, 258, 172, 266
      Annotation: 
       Subtype: Link
       Rect: 173, 258, 197, 266
      Annotation: 
       Subtype: Link
       Rect: 451, 248, 459, 256
      Annotation: 
       Subtype: Link
       Rect: 461, 248, 484, 256
      Annotation: 
       Subtype: Link
       Rect: 394, 228, 406, 236
      Annotation: 
       Subtype: Link
       Rect: 408, 228, 431, 236
      Annotation: 
       Subtype: Link
       Rect: 198, 208, 202, 216
      Annotation: 
       Subtype: Link
       Rect: 204, 208, 230, 216
      Annotation: 
       Subtype: Link
       Rect: 140, 188, 148, 196
      Annotation: 
       Subtype: Link
       Rect: 150, 188, 173, 196
      Annotation: 
       Subtype: Link
       Rect: 397, 168, 408, 176
      Annotation: 
       Subtype: Link
       Rect: 410, 168, 452, 176
      Annotation: 
       Subtype: Link
       Rect: 140, 148, 152, 156
      Annotation: 
       Subtype: Link
       Rect: 154, 148, 184, 156
      Annotation: 
       Subtype: Link
       Rect: 299, 138, 311, 146
      Annotation: 
       Subtype: Link
       Rect: 312, 138, 336, 146
      Annotation: 
       Subtype: Link
       Rect: 165, 118, 173, 126
      Annotation: 
       Subtype: Link
       Rect: 175, 118, 190, 126
      Annotation: 
       Subtype: Link
       Rect: 207, 98, 215, 106
      Annotation: 
       Subtype: Link
       Rect: 217, 98, 244, 106
      Annotation: 
       Subtype: Link
       Rect: 263, 78, 271, 86
      Annotation: 
       Subtype: Link
       Rect: 272, 78, 299, 86
      Annotation: 
       Subtype: Link
       Rect: 393, 58, 401, 66
      Annotation: 
       Subtype: Link
       Rect: 403, 58, 430, 66
    Page: 
     Sequence: 38
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 348, 760, 356, 769
      Annotation: 
       Subtype: Link
       Rect: 358, 760, 377, 769
      Annotation: 
       Subtype: Link
       Rect: 396, 740, 404, 749
      Annotation: 
       Subtype: Link
       Rect: 406, 740, 433, 749
      Annotation: 
       Subtype: Link
       Rect: 359, 720, 367, 729
      Annotation: 
       Subtype: Link
       Rect: 369, 720, 400, 729
      Annotation: 
       Subtype: Link
       Rect: 140, 700, 148, 709
      Annotation: 
       Subtype: Link
       Rect: 150, 700, 173, 709
      Annotation: 
       Subtype: Link
       Rect: 439, 690, 447, 699
      Annotation: 
       Subtype: Link
       Rect: 449, 690, 476, 699
      Annotation: 
       Subtype: Link
       Rect: 140, 670, 148, 679
      Annotation: 
       Subtype: Link
       Rect: 150, 670, 173, 679
      Annotation: 
       Subtype: Link
       Rect: 140, 650, 148, 659
      Annotation: 
       Subtype: Link
       Rect: 150, 650, 181, 659
      Annotation: 
       Subtype: Link
       Rect: 315, 630, 327, 639
      Annotation: 
       Subtype: Link
       Rect: 329, 630, 348, 639
      Annotation: 
       Subtype: Link
       Rect: 516, 610, 523, 619
      Annotation: 
       Subtype: Link
       Rect: 525, 610, 552, 619
      Annotation: 
       Subtype: Link
       Rect: 490, 590, 498, 599
      Annotation: 
       Subtype: Link
       Rect: 500, 590, 515, 599
      Annotation: 
       Subtype: Link
       Rect: 449, 570, 461, 579
      Annotation: 
       Subtype: Link
       Rect: 462, 570, 482, 579
      Annotation: 
       Subtype: Link
       Rect: 416, 550, 424, 559
      Annotation: 
       Subtype: Link
       Rect: 426, 550, 449, 559
      Annotation: 
       Subtype: Link
       Rect: 220, 530, 231, 539
      Annotation: 
       Subtype: Link
       Rect: 233, 530, 256, 539
      Annotation: 
       Subtype: Link
       Rect: 341, 510, 353, 519
      Annotation: 
       Subtype: Link
       Rect: 355, 510, 378, 519
      Annotation: 
       Subtype: Link
       Rect: 140, 490, 144, 499
      Annotation: 
       Subtype: Link
       Rect: 146, 490, 175, 499
      Annotation: 
       Subtype: Link
       Rect: 258, 470, 270, 479
      Annotation: 
       Subtype: Link
       Rect: 272, 470, 295, 479
      Annotation: 
       Subtype: Link
       Rect: 260, 450, 268, 459
      Annotation: 
       Subtype: Link
       Rect: 270, 450, 289, 459
      Annotation: 
       Subtype: Link
       Rect: 462, 430, 470, 439
      Annotation: 
       Subtype: Link
       Rect: 471, 430, 502, 439
      Annotation: 
       Subtype: Link
       Rect: 140, 400, 152, 409
      Annotation: 
       Subtype: Link
       Rect: 154, 400, 184, 409
      Annotation: 
       Subtype: Link
       Rect: 196, 380, 200, 389
      Annotation: 
       Subtype: Link
       Rect: 202, 380, 217, 389
      Annotation: 
       Subtype: Link
       Rect: 489, 370, 497, 379
      Annotation: 
       Subtype: Link
       Rect: 499, 370, 522, 379
      Annotation: 
       Subtype: Link
       Rect: 318, 350, 322, 359
      Annotation: 
       Subtype: Link
       Rect: 324, 350, 335, 359
      Annotation: 
       Subtype: Link
       Rect: 463, 340, 475, 349
      Annotation: 
       Subtype: Link
       Rect: 477, 340, 500, 349
      Annotation: 
       Subtype: Link
       Rect: 509, 320, 517, 329
      Annotation: 
       Subtype: Link
       Rect: 519, 320, 546, 329
      Annotation: 
       Subtype: Link
       Rect: 284, 300, 288, 309
      Annotation: 
       Subtype: Link
       Rect: 289, 300, 320, 309
      Annotation: 
       Subtype: Link
       Rect: 377, 280, 385, 289
      Annotation: 
       Subtype: Link
       Rect: 387, 280, 414, 289
      Annotation: 
       Subtype: Link
       Rect: 140, 260, 144, 269
      Annotation: 
       Subtype: Link
       Rect: 146, 260, 165, 269
      Annotation: 
       Subtype: Link
       Rect: 163, 240, 167, 249
      Annotation: 
       Subtype: Link
       Rect: 169, 240, 192, 249
      Annotation: 
       Subtype: Link
       Rect: 222, 220, 226, 229
      Annotation: 
       Subtype: Link
       Rect: 228, 220, 259, 229
      Annotation: 
       Subtype: Link
       Rect: 159, 200, 167, 209
      Annotation: 
       Subtype: Link
       Rect: 169, 200, 192, 209
      Annotation: 
       Subtype: Link
       Rect: 255, 180, 263, 189
      Annotation: 
       Subtype: Link
       Rect: 264, 180, 292, 189
      Annotation: 
       Subtype: Link
       Rect: 340, 160, 344, 169
      Annotation: 
       Subtype: Link
       Rect: 346, 160, 373, 169
      Annotation: 
       Subtype: Link
       Rect: 257, 140, 261, 149
      Annotation: 
       Subtype: Link
       Rect: 263, 140, 290, 149
      Annotation: 
       Subtype: Link
       Rect: 506, 130, 518, 139
      Annotation: 
       Subtype: Link
       Rect: 519, 130, 543, 139
      Annotation: 
       Subtype: Link
       Rect: 416, 120, 550, 129
      Annotation: 
       Subtype: Link
       Rect: 140, 110, 234, 119
      Annotation: 
       Subtype: Link
       Rect: 322, 90, 330, 99
      Annotation: 
       Subtype: Link
       Rect: 332, 90, 355, 99
      Annotation: 
       Subtype: Link
       Rect: 396, 70, 400, 79
      Annotation: 
       Subtype: Link
       Rect: 402, 70, 421, 79
    Page: 
     Sequence: 39
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 140, 750, 152, 759
      Annotation: 
       Subtype: Link
       Rect: 154, 750, 177, 759
      Annotation: 
       Subtype: Link
       Rect: 165, 730, 169, 739
      Annotation: 
       Subtype: Link
       Rect: 171, 730, 194, 739
      Annotation: 
       Subtype: Link
       Rect: 237, 710, 241, 719
      Annotation: 
       Subtype: Link
       Rect: 243, 710, 266, 719
      Annotation: 
       Subtype: Link
       Rect: 171, 680, 179, 689
      Annotation: 
       Subtype: Link
       Rect: 181, 680, 212, 689
      Annotation: 
       Subtype: Link
       Rect: 459, 670, 467, 679
      Annotation: 
       Subtype: Link
       Rect: 469, 670, 485, 679
      Annotation: 
       Subtype: Link
       Rect: 318, 650, 326, 659
      Annotation: 
       Subtype: Link
       Rect: 327, 650, 351, 659
      Annotation: 
       Subtype: Link
       Rect: 343, 630, 354, 639
      Annotation: 
       Subtype: Link
       Rect: 356, 630, 375, 639
      Annotation: 
       Subtype: Link
       Rect: 236, 610, 248, 619
      Annotation: 
       Subtype: Link
       Rect: 250, 610, 273, 619
      Annotation: 
       Subtype: Link
       Rect: 276, 590, 280, 599
      Annotation: 
       Subtype: Link
       Rect: 282, 590, 289, 599
      Annotation: 
       Subtype: Link
       Rect: 469, 580, 480, 589
      Annotation: 
       Subtype: Link
       Rect: 482, 580, 509, 589
      Annotation: 
       Subtype: Link
       Rect: 490, 560, 498, 569
      Annotation: 
       Subtype: Link
       Rect: 499, 560, 523, 569
      Annotation: 
       Subtype: Link
       Rect: 140, 540, 152, 549
      Annotation: 
       Subtype: Link
       Rect: 154, 540, 173, 549
      Annotation: 
       Subtype: Link
       Rect: 237, 520, 245, 529
      Annotation: 
       Subtype: Link
       Rect: 246, 520, 277, 529
      Annotation: 
       Subtype: Link
       Rect: 184, 500, 196, 509
      Annotation: 
       Subtype: Link
       Rect: 198, 500, 221, 509
      Annotation: 
       Subtype: Link
       Rect: 229, 480, 236, 489
      Annotation: 
       Subtype: Link
       Rect: 238, 480, 254, 489
      Annotation: 
       Subtype: Link
       Rect: 294, 460, 301, 469
      Annotation: 
       Subtype: Link
       Rect: 303, 460, 326, 469
      Annotation: 
       Subtype: Link
       Rect: 180, 440, 188, 449
      Annotation: 
       Subtype: Link
       Rect: 190, 440, 213, 449
      Annotation: 
       Subtype: Link
       Rect: 252, 420, 264, 429
      Annotation: 
       Subtype: Link
       Rect: 266, 420, 293, 429
      Annotation: 
       Subtype: Link
       Rect: 301, 410, 313, 419
      Annotation: 
       Subtype: Link
       Rect: 315, 410, 331, 419
      Annotation: 
       Subtype: Link
       Rect: 357, 400, 523, 409
      Annotation: 
       Subtype: Link
       Rect: 446, 380, 454, 389
      Annotation: 
       Subtype: Link
       Rect: 456, 380, 467, 389
      Annotation: 
       Subtype: Link
       Rect: 140, 350, 148, 359
      Annotation: 
       Subtype: Link
       Rect: 150, 350, 165, 359
      Annotation: 
       Subtype: Link
       Rect: 331, 330, 339, 339
      Annotation: 
       Subtype: Link
       Rect: 341, 330, 360, 339
      Annotation: 
       Subtype: Link
       Rect: 140, 310, 148, 319
      Annotation: 
       Subtype: Link
       Rect: 150, 310, 165, 319
      Annotation: 
       Subtype: Link
       Rect: 140, 280, 156, 289
      Annotation: 
       Subtype: Link
       Rect: 157, 280, 181, 289
      Annotation: 
       Subtype: Link
       Rect: 412, 260, 428, 269
      Annotation: 
       Subtype: Link
       Rect: 429, 260, 456, 269
      Annotation: 
       Subtype: Link
       Rect: 487, 240, 498, 249
      Annotation: 
       Subtype: Link
       Rect: 500, 240, 516, 249
      Annotation: 
       Subtype: Link
       Rect: 140, 210, 152, 219
      Annotation: 
       Subtype: Link
       Rect: 154, 210, 173, 219
      Annotation: 
       Subtype: Link
       Rect: 240, 190, 247, 199
      Annotation: 
       Subtype: Link
       Rect: 249, 190, 261, 199
      Annotation: 
       Subtype: Link
       Rect: 146, 160, 158, 169
      Annotation: 
       Subtype: Link
       Rect: 160, 160, 183, 169
      Annotation: 
       Subtype: Link
       Rect: 318, 140, 326, 149
      Annotation: 
       Subtype: Link
       Rect: 328, 140, 355, 149
      Annotation: 
       Subtype: Link
       Rect: 397, 120, 405, 129
      Annotation: 
       Subtype: Link
       Rect: 407, 120, 422, 129
      Annotation: 
       Subtype: Link
       Rect: 442, 100, 454, 109
      Annotation: 
       Subtype: Link
       Rect: 456, 100, 467, 109
      Annotation: 
       Subtype: Link
       Rect: 308, 80, 316, 89
      Annotation: 
       Subtype: Link
       Rect: 318, 80, 333, 89
      Annotation: 
       Subtype: Link
       Rect: 140, 60, 152, 69
      Annotation: 
       Subtype: Link
       Rect: 154, 60, 181, 69
    Page: 
     Sequence: 40
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 140, 760, 148, 769
      Annotation: 
       Subtype: Link
       Rect: 150, 760, 165, 769
      Annotation: 
       Subtype: Link
       Rect: 236, 740, 244, 749
      Annotation: 
       Subtype: Link
       Rect: 245, 740, 257, 749
      Annotation: 
       Subtype: Link
       Rect: 359, 720, 367, 729
      Annotation: 
       Subtype: Link
       Rect: 369, 720, 396, 729
      Annotation: 
       Subtype: Link
       Rect: 507, 710, 515, 719
      Annotation: 
       Subtype: Link
       Rect: 517, 710, 544, 719
      Annotation: 
       Subtype: Link
       Rect: 382, 690, 390, 699
      Annotation: 
       Subtype: Link
       Rect: 392, 690, 419, 699
      Annotation: 
       Subtype: Link
       Rect: 475, 670, 479, 679
      Annotation: 
       Subtype: Link
       Rect: 481, 670, 508, 679
      Annotation: 
       Subtype: Link
       Rect: 182, 650, 193, 659
      Annotation: 
       Subtype: Link
       Rect: 195, 650, 218, 659
      Annotation: 
       Subtype: Link
       Rect: 422, 630, 430, 639
      Annotation: 
       Subtype: Link
       Rect: 432, 630, 455, 639
      Annotation: 
       Subtype: Link
       Rect: 458, 610, 461, 619
      Annotation: 
       Subtype: Link
       Rect: 463, 610, 493, 619
      Annotation: 
       Subtype: Link
       Rect: 232, 580, 240, 589
      Annotation: 
       Subtype: Link
       Rect: 242, 580, 265, 589
      Annotation: 
       Subtype: Link
       Rect: 520, 570, 527, 579
      Annotation: 
       Subtype: Link
       Rect: 529, 570, 552, 579
      Annotation: 
       Subtype: Link
       Rect: 140, 550, 148, 559
      Annotation: 
       Subtype: Link
       Rect: 150, 550, 180, 559
      Annotation: 
       Subtype: Link
       Rect: 475, 530, 482, 539
      Annotation: 
       Subtype: Link
       Rect: 484, 530, 488, 539
      Annotation: 
       Subtype: Link
       Rect: 489, 510, 501, 519
      Annotation: 
       Subtype: Link
       Rect: 502, 510, 526, 519
      Annotation: 
       Subtype: Link
       Rect: 361, 480, 372, 489
      Annotation: 
       Subtype: Link
       Rect: 374, 480, 397, 489
      Annotation: 
       Subtype: Link
       Rect: 178, 460, 186, 469
      Annotation: 
       Subtype: Link
       Rect: 187, 460, 218, 469
      Annotation: 
       Subtype: Link
       Rect: 187, 430, 195, 439
      Annotation: 
       Subtype: Link
       Rect: 197, 430, 224, 439
      Annotation: 
       Subtype: Link
       Rect: 414, 410, 422, 419
      Annotation: 
       Subtype: Link
       Rect: 424, 410, 447, 419
      Annotation: 
       Subtype: Link
       Rect: 404, 390, 412, 399
      Annotation: 
       Subtype: Link
       Rect: 414, 390, 426, 399
      Annotation: 
       Subtype: Link
       Rect: 163, 360, 171, 369
      Annotation: 
       Subtype: Link
       Rect: 173, 360, 196, 369
      Annotation: 
       Subtype: Link
       Rect: 187, 330, 195, 339
      Annotation: 
       Subtype: Link
       Rect: 197, 330, 224, 339
      Annotation: 
       Subtype: Link
       Rect: 507, 310, 515, 319
      Annotation: 
       Subtype: Link
       Rect: 517, 310, 540, 319
      Annotation: 
       Subtype: Link
       Rect: 254, 290, 262, 299
      Annotation: 
       Subtype: Link
       Rect: 264, 290, 287, 299
      Annotation: 
       Subtype: Link
       Rect: 519, 280, 527, 289
      Annotation: 
       Subtype: Link
       Rect: 529, 280, 552, 289
      Annotation: 
       Subtype: Link
       Rect: 324, 260, 332, 269
      Annotation: 
       Subtype: Link
       Rect: 334, 260, 357, 269
      Annotation: 
       Subtype: Link
       Rect: 401, 240, 409, 249
      Annotation: 
       Subtype: Link
       Rect: 410, 240, 441, 249
      Annotation: 
       Subtype: Link
       Rect: 293, 220, 297, 229
      Annotation: 
       Subtype: Link
       Rect: 299, 220, 326, 229
      Annotation: 
       Subtype: Link
       Rect: 378, 200, 386, 209
      Annotation: 
       Subtype: Link
       Rect: 388, 200, 400, 209
      Annotation: 
       Subtype: Link
       Rect: 183, 180, 191, 189
      Annotation: 
       Subtype: Link
       Rect: 193, 180, 212, 189
      Annotation: 
       Subtype: Link
       Rect: 270, 160, 278, 169
      Annotation: 
       Subtype: Link
       Rect: 280, 160, 295, 169
      Annotation: 
       Subtype: Link
       Rect: 430, 140, 438, 149
      Annotation: 
       Subtype: Link
       Rect: 439, 140, 455, 149
      Annotation: 
       Subtype: Link
       Rect: 261, 120, 273, 129
      Annotation: 
       Subtype: Link
       Rect: 275, 120, 302, 129
      Annotation: 
       Subtype: Link
       Rect: 140, 100, 148, 109
      Annotation: 
       Subtype: Link
       Rect: 150, 100, 177, 109
      Annotation: 
       Subtype: Link
       Rect: 270, 80, 281, 89
      Annotation: 
       Subtype: Link
       Rect: 283, 80, 306, 89
  Checksum: 04bd9923
   Type: CRC32
  Checksum: e0304afa88855f048d732ba8c8c3e5ae
   Type: MD5
  Checksum: 4b8012df28533f0e5010effb9e925dbace173306
   Type: SHA-1
  Checksum: 2880f7e6a10d1b3181b3bfe16896c542476488df54da166c64b6df8dc546124c
   Type: SHA-256