8078ba27ee154084ec411481165c7db3 pmc_10048316.pdf 42d495f47cac7389acf8e123b8facb7ce07e5940 pmc_10048316.pdf 4ee394845b96f5dbfbd6b41ec2dea3daf4fe254110b9f95d8f51e3f452de8f15 pmc_10048316.pdf Title: Intensive Rehabilitation Program in Older Adults with Stroke: Therapy Content and Feasibility—Preliminary Results from the BRAIN-CONNECTS Study Subject: The main objective was to assess the feasibility of an intensive rehabilitation program (IRP) for stroke patients; and secondly, to detect eventual age-related differences in content, duration, tolerability, and safety in a prospective observational cohort of patients diagnosed with subacute stroke, admitted to inpatient rehabilitation (BRAIN-CONNECTS project). Activities during physical, occupational and speech therapy, and time dedicated to each one were recorded. Forty-five subjects (63.0 years, 77.8% men) were included. The mean time of therapy was 173.8 (SD 31.5) minutes per day. The only age-related differences when comparing patients 65 and <65 years were a shorter time allocated for occupational therapy (-7.5 min (95% CI -12.5 to -2.6), p = 0.004) and a greater need of speech therapy (90% vs. 44%) in the older adults. Gait training, movement patterns of upper limbs, and lingual praxis were the most commonly performed activities. Regarding tolerability and safety, there were no losses to follow-up, and the attendance ratio was above 95%. No adverse events occurred during any session in all patients. Conclusion: IRP is a feasible intervention in patients with subacute stroke, regardless of age, and there are no relevant differences on content or duration of therapy. Keywords: feasibility; stroke; intensive rehabilitation program; older adults Author: Andrea Morgado-Pérez, Maria Coll-Molinos, Ruben Valero, Miriam Llobet, Nohora Rueda, Andrea Martínez, Sonia Nieto, Cindry Ramírez-Fuentes, Dolores Sánchez-Rodríguez, Ester Marco, Josep Puig and Esther Duarte Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Mar 7 09:54:27 2023 CET ModDate: Tue Mar 7 09:57:51 2023 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1402299 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- UYBGVU+VnURWPalladioL Type 1 Custom yes yes no 10 0 FOWXNM+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 VVPONN+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 CNOSGF+URWPalladioL-Ital Type 1 Custom yes yes no 24 0 CNXSVA+CMSY10 Type 1 Builtin yes yes no 28 0 IOJCNK+VnURWPalladioL-Bold Type 1 Custom yes yes no 32 0 LWQXII+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 50 0 IRWHZX+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 53 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes no 84 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-29 02:32:23 CEST RepresentationInformation: pmc_10048316.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-28 02:24:03 CEST Size: 1402299 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 221 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Children: Item: Title: Study Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Study Setting Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: Participants Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Item: Title: Intensive Rehabilitation Program Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@262b2c86 Item: Title: Treatment Record Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@371a67ec Item: Title: Study Endpoints Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5ed828d Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@50d0686 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a3d45bd Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1e7c7811 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@77ec78b9 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1a3869f4 Info: Title: Intensive Rehabilitation Program in Older Adults with Stroke: Therapy Content and Feasibility Preliminary Results from the BRAIN-CONNECTS Study Author: Andrea Morgado-Pérez, Maria Coll-Molinos, Ruben Valero, Miriam Llobet, Nohora Rueda, Andrea Martínez, Sonia Nieto, Cindry Ramírez-Fuentes, Dolores Sánchez-Rodríguez, Ester Marco, Josep Puig and Esther Duarte Subject: The main objective was to assess the feasibility of an intensive rehabilitation program (IRP) for stroke patients; and secondly, to detect eventual age-related differences in content, duration, tolerability, and safety in a prospective observational cohort of patients diagnosed with subacute stroke, admitted to inpatient rehabilitation (BRAIN-CONNECTS project). Activities during physical, occupational and speech therapy, and time dedicated to each one were recorded. Forty-five subjects (63.0 years, 77.8% men) were included. The mean time of therapy was 173.8 (SD 31.5) minutes per day. The only age-related differences when comparing patients 65 and <65 years were a shorter time allocated for occupational therapy (-7.5 min (95% CI -12.5 to -2.6), p = 0.004) and a greater need of speech therapy (90% vs. 44%) in the older adults. Gait training, movement patterns of upper limbs, and lingual praxis were the most commonly performed activities. Regarding tolerability and safety, there were no losses to follow-up, and the attendance ratio was above 95%. No adverse events occurred during any session in all patients. Conclusion: IRP is a feasible intervention in patients with subacute stroke, regardless of age, and there are no relevant differences on content or duration of therapy. 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