74adcef856e507e82442a110d1b2ba97 pmc_10060861.pdf bb66e0ed63df685e24623ba91850fed51ae2cf0b pmc_10060861.pdf 1d5ccaf76e6a89b8088049e83f490e8054ae01be2d89011f913cadb901800763 pmc_10060861.pdf Title: Brain system segregation and pain catastrophizing in chronic pain progression Subject: Pain processing involves emotional and cognitive factors that can modify pain perception. Keywords: chronic pain, functional magnetic resonance imaging, resilience, system segregation, pain catastrophizing, psychological distress Author: Selma Delgado-Gallén Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Sat Mar 11 10:13:09 2023 CET ModDate: Sat Mar 11 12:04:06 2023 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2303035 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- FJVPYV+MinionPro-Regular Type 1 Custom yes yes no 27 0 THWNNR+MuseoSans-700 Type 1 Custom yes yes no 28 0 BNKVZT+MuseoSans-300 Type 1 Custom yes yes no 29 0 XFWJUN+MuseoSans-300Italic Type 1 Custom yes yes no 34 0 EYVEHG+MuseoSans-500 Type 1 Custom yes yes no 35 0 CMERJW+MTGU Type 1 Builtin yes yes no 36 0 BWBHZI+MinionPro-Bold Type 1 Custom yes yes no 287 0 VASGMA+MTSYN Type 1 Builtin yes yes no 288 0 MJQNFJ+RBLMI Type 1 Builtin yes yes no 296 0 XOULEO+MinionPro-It Type 1 Custom yes yes no 300 0 FXXYXK+MuseoSans-500Italic Type 1 Custom yes yes no 502 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-25 02:30:04 CEST RepresentationInformation: pmc_10060861.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-19 02:20:15 CEST Size: 2303035 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 1155 FreeObjects: 7 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Brain system segregation and pain catastrophizing in chronic pain progression Children: Item: Title: 1. Introduction Item: Title: 2. Materials and methods Children: Item: Title: 2.1. Participants and study design Item: Title: 2.2. Assessments Children: Item: Title: 2.2.1. Pain: Clinical symptoms Item: Title: 2.2.2. Pain experience over time: Intensity and affective interference Item: Title: 2.2.3. Pain catastrophizing Item: Title: 2.2.4. Health-related questionnaires Item: Title: 2.3. MRI acquisition and analysis Children: Item: Title: 2.3.1. MRI acquisition parameters Item: Title: 2.3.2. MRI preprocessing Item: Title: 2.3.3. Functional magnetic resonance imaging: System segregation Item: Title: 2.4. Data analysis Children: Item: Title: 2.4.1. Comparisons between no pain and pain groups Item: Title: 2.4.2. Correlations between pain variables, psychological aspects, and system segregation Item: Title: 2.4.3. Description of longitudinal pain progression Item: Title: 2.4.4. Regression models within the chronic pain group Item: Title: 2.4.5. Statistical analyses Item: Title: 3. Results Children: Item: Title: 3.1. Differences between no pain and chronic pain group Item: Title: 3.2. Correlations in psychological aspects and pain variables Item: Title: 3.3. Description of longitudinal pain progression Item: Title: 3.4. Chronic pain and the role of brain networks in pain progression Item: Title: 4. Discussion Children: Item: Title: 4.1. Differences between groups and pain characteristics Item: Title: 4.2. Pain characteristics and their correlations with psychological aspects Item: Title: 4.3. Catastrophizing is associated with pain progression Item: Title: 4.4. System segregation and pain experience progression Item: Title: 4.5. Default mode and dorsoattentional networks interactions with helplessness Item: Title: 4.6. Limitations and future directions Item: Title: 5. Conclusion Item: Title: Data availability statement Item: Title: Ethics statement Item: Title: Author contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Conflict of interest Item: Title: Publisher's note Item: Title: References Info: Title: Brain system segregation and pain catastrophizing in chronic pain progression Author: Selma Delgado-Gallén Subject: Pain processing involves emotional and cognitive factors that can modify pain perception. Keywords: chronic pain, functional magnetic resonance imaging, resilience, system segregation, pain catastrophizing, psychological distress Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Sat Mar 11 10:43:09 CET 2023 ModDate: Sat Mar 11 12:34:06 CET 2023 ID: 0xe592431fd852fdcafbb3b4e4dde1d39a, 0x8caf46ec4597cd4fb73b415ef333a1f6 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: VASGMA+MTSYN FontSubset: true FirstChar: 0 LastChar: 68 FontDescriptor: FontName: VASGMA+MTSYN Flags: Symbolic FontBBox: 0, -954, 1043, 900 FontFile: true Font: BaseFont: XFWJUN+MuseoSans-300Italic FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: XFWJUN+MuseoSans-300Italic Flags: Symbolic FontBBox: -245, -210, 1030, 883 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: EYVEHG+MuseoSans-500 FontSubset: true FirstChar: 3 LastChar: 241 FontDescriptor: FontName: EYVEHG+MuseoSans-500 Flags: Symbolic FontBBox: -121, -210, 1088, 892 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: CMERJW+MTGU FontSubset: true FirstChar: 98 LastChar: 98 FontDescriptor: FontName: CMERJW+MTGU Flags: Symbolic FontBBox: 25, -213, 839, 683 FontFile: true Font: BaseFont: FXXYXK+MuseoSans-500Italic FontSubset: true FirstChar: 70 LastChar: 116 FontDescriptor: FontName: FXXYXK+MuseoSans-500Italic Flags: Symbolic FontBBox: -249, -210, 1047, 892 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: MJQNFJ+RBLMI FontSubset: true FirstChar: 58 LastChar: 62 FontDescriptor: FontName: MJQNFJ+RBLMI Flags: Symbolic FontBBox: -11, -230, 987, 750 FontFile: true Font: BaseFont: FJVPYV+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: FJVPYV+MinionPro-Regular Flags: Symbolic FontBBox: -289, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: THWNNR+MuseoSans-700 FontSubset: true FirstChar: 2 LastChar: 122 FontDescriptor: FontName: THWNNR+MuseoSans-700 Flags: Symbolic FontBBox: -125, -210, 1126, 902 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XOULEO+MinionPro-It FontSubset: true FirstChar: 19 LastChar: 237 FontDescriptor: FontName: XOULEO+MinionPro-It Flags: Symbolic FontBBox: -201, -360, 1684, 919 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: BNKVZT+MuseoSans-300 FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: BNKVZT+MuseoSans-300 Flags: Symbolic FontBBox: -118, -210, 1088, 883 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: BWBHZI+MinionPro-Bold FontSubset: true FirstChar: 49 LastChar: 117 FontDescriptor: FontName: BWBHZI+MinionPro-Bold Flags: Symbolic FontBBox: -318, -360, 1684, 917 FontFile: true EncodingDictionary: Differences: true XMP: chronic pain, functional magnetic resonance imaging, resilience, system segregation, pain catastrophizing, psychological distress pdfTeX-1.40.15 1.5 application/pdf fnins-17-1148176.tex Brain system segregation and pain catastrophizing in chronic pain progression Pain processing involves emotional and cognitive factors that can modify pain perception. Selma Delgado-Gallén MD Soler María Cabello-Toscano Kilian Abellaneda-Pérez Javier Solana-Sánchez Goretti España-Irla Alba Roca-Ventura David Bartrés-Faz Josep M. Tormos Alvaro Pascual-Leone Gabriele Cattaneo 2023-03-11T14:43:09+05:30 chronic pain functional magnetic resonance imaging resilience system segregation pain catastrophizing psychological distress 2023-03-11T14:43:09+05:30 2023-03-11T16:34:06+05:30 2023-03-11T16:34:06+05:30 LaTeX with hyperref package uuid:59590ae4-6262-4b1d-9d1d-1339b6c46262 uuid:b3a2ccef-dfa2-495f-b7cd-8ac0b3a4b453 Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 48, 791, 237, 807 Annotation: Subtype: Link Rect: 433, 798, 514, 807 Annotation: Subtype: Link Rect: 433, 790, 523, 798 Annotation: Subtype: Link Rect: 433, 779, 543, 789 Annotation: Subtype: Link Rect: 48, 704, 126, 721 Annotation: Subtype: Link Rect: 62, 382, 153, 389 Annotation: Subtype: Link Rect: 158, 314, 186, 321 Annotation: Subtype: Link Rect: 48, 305, 84, 312 Annotation: Subtype: Link Rect: 84, 305, 120, 312 Annotation: Subtype: Link Rect: 120, 305, 146, 312 Annotation: Subtype: Link Rect: 146, 305, 172, 312 Annotation: Subtype: Link Rect: 213, 650, 546, 722 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 97, 525, 140, 536 ActionDest: 822 Annotation: Subtype: Link Rect: 144, 525, 163, 536 ActionDest: 822 Annotation: Subtype: Link Rect: 162, 489, 236, 500 ActionDest: 822 Annotation: Subtype: Link Rect: 238, 489, 257, 500 ActionDest: 822 Annotation: Subtype: Link Rect: 90, 465, 115, 476 ActionDest: 933 Annotation: Subtype: Link Rect: 118, 465, 137, 476 ActionDest: 933 Annotation: Subtype: Link Rect: 140, 465, 159, 476 ActionDest: 933 Annotation: Subtype: Link Rect: 162, 465, 224, 476 ActionDest: 895 Annotation: Subtype: Link Rect: 227, 465, 246, 476 ActionDest: 895 Annotation: Subtype: Link Rect: 249, 465, 291, 476 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 453, 76, 464 ActionDest: 933 Annotation: Subtype: Link Rect: 78, 453, 97, 464 ActionDest: 933 Annotation: Subtype: Link Rect: 100, 453, 178, 464 ActionDest: 822 Annotation: Subtype: Link Rect: 180, 453, 200, 464 ActionDest: 822 Annotation: Subtype: Link Rect: 179, 369, 238, 379 ActionDest: 822 Annotation: Subtype: Link Rect: 245, 369, 264, 379 ActionDest: 822 Annotation: Subtype: Link Rect: 165, 345, 216, 355 ActionDest: 822 Annotation: Subtype: Link Rect: 221, 345, 240, 355 ActionDest: 822 Annotation: Subtype: Link Rect: 245, 345, 291, 355 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 332, 70, 343 ActionDest: 895 Annotation: Subtype: Link Rect: 74, 332, 94, 343 ActionDest: 895 Annotation: Subtype: Link Rect: 99, 332, 202, 343 ActionDest: 822 Annotation: Subtype: Link Rect: 207, 332, 227, 343 ActionDest: 822 Annotation: Subtype: Link Rect: 76, 296, 123, 307 ActionDest: 933 Annotation: Subtype: Link Rect: 126, 296, 145, 307 ActionDest: 933 Annotation: Subtype: Link Rect: 238, 296, 289, 307 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 285, 67, 295 ActionDest: 822 Annotation: Subtype: Link Rect: 220, 260, 263, 271 ActionDest: 822 Annotation: Subtype: Link Rect: 266, 260, 286, 271 ActionDest: 822 Annotation: Subtype: Link Rect: 169, 224, 196, 235 ActionDest: 895 Annotation: Subtype: Link Rect: 198, 224, 218, 235 ActionDest: 895 Annotation: Subtype: Link Rect: 220, 224, 267, 235 ActionDest: 822 Annotation: Subtype: Link Rect: 269, 224, 289, 235 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 212, 85, 223 ActionDest: 895 Annotation: Subtype: Link Rect: 87, 212, 106, 223 ActionDest: 895 Annotation: Subtype: Link Rect: 242, 200, 289, 211 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 188, 67, 199 ActionDest: 822 Annotation: Subtype: Link Rect: 134, 188, 180, 199 ActionDest: 822 Annotation: Subtype: Link Rect: 184, 188, 203, 199 ActionDest: 822 Annotation: Subtype: Link Rect: 253, 152, 291, 163 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 140, 66, 151 ActionDest: 933 Annotation: Subtype: Link Rect: 68, 140, 88, 151 ActionDest: 933 Annotation: Subtype: Link Rect: 133, 129, 175, 139 ActionDest: 822 Annotation: Subtype: Link Rect: 177, 129, 197, 139 ActionDest: 822 Annotation: Subtype: Link Rect: 150, 68, 195, 79 ActionDest: 822 Annotation: Subtype: Link Rect: 198, 68, 218, 79 ActionDest: 822 Annotation: Subtype: Link Rect: 221, 68, 266, 79 ActionDest: 895 Annotation: Subtype: Link Rect: 269, 68, 289, 79 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 56, 82, 67 ActionDest: 933 Annotation: Subtype: Link Rect: 86, 56, 105, 67 ActionDest: 933 Annotation: Subtype: Link Rect: 109, 56, 175, 67 ActionDest: 822 Annotation: Subtype: Link Rect: 178, 56, 197, 67 ActionDest: 822 Annotation: Subtype: Link Rect: 201, 56, 289, 67 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 603, 322, 614 ActionDest: 895 Annotation: Subtype: Link Rect: 325, 603, 371, 614 ActionDest: 895 Annotation: Subtype: Link Rect: 375, 603, 394, 614 ActionDest: 895 Annotation: Subtype: Link Rect: 397, 603, 435, 614 ActionDest: 933 Annotation: Subtype: Link Rect: 438, 603, 457, 614 ActionDest: 933 Annotation: Subtype: Link Rect: 460, 603, 521, 614 ActionDest: 822 Annotation: Subtype: Link Rect: 525, 603, 544, 614 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 591, 373, 602 ActionDest: 895 Annotation: Subtype: Link Rect: 375, 591, 394, 602 ActionDest: 895 Annotation: Subtype: Link Rect: 476, 555, 522, 566 ActionDest: 895 Annotation: Subtype: Link Rect: 525, 555, 544, 566 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 543, 345, 554 ActionDest: 822 Annotation: Subtype: Link Rect: 347, 543, 367, 554 ActionDest: 822 Annotation: Subtype: Link Rect: 369, 543, 418, 554 ActionDest: 822 Annotation: Subtype: Link Rect: 420, 543, 439, 554 ActionDest: 822 Annotation: Subtype: Link Rect: 441, 543, 484, 554 ActionDest: 895 Annotation: Subtype: Link Rect: 486, 543, 505, 554 ActionDest: 895 Annotation: Subtype: Link Rect: 508, 543, 546, 554 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 533, 322, 542 ActionDest: 895 Annotation: Subtype: Link Rect: 325, 533, 344, 542 ActionDest: 895 Annotation: Subtype: Link Rect: 347, 533, 394, 542 ActionDest: 895 Annotation: Subtype: Link Rect: 396, 533, 415, 542 ActionDest: 895 Annotation: Subtype: Link Rect: 418, 533, 482, 542 ActionDest: 822 Annotation: Subtype: Link Rect: 484, 533, 503, 542 ActionDest: 822 Annotation: Subtype: Link Rect: 506, 533, 544, 542 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 519, 322, 530 ActionDest: 895 Annotation: Subtype: Link Rect: 326, 519, 433, 530 ActionDest: 933 Annotation: Subtype: Link Rect: 438, 519, 457, 530 ActionDest: 933 Annotation: Subtype: Link Rect: 461, 519, 506, 530 ActionDest: 822 Annotation: Subtype: Link Rect: 510, 519, 529, 530 ActionDest: 822 Annotation: Subtype: Link Rect: 533, 519, 546, 530 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 508, 349, 518 ActionDest: 822 Annotation: Subtype: Link Rect: 351, 508, 370, 518 ActionDest: 822 Annotation: Subtype: Link Rect: 475, 436, 519, 447 ActionDest: 933 Annotation: Subtype: Link Rect: 521, 436, 541, 447 ActionDest: 933 Annotation: Subtype: Link Rect: 468, 401, 521, 411 ActionDest: 822 Annotation: Subtype: Link Rect: 525, 401, 544, 411 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 389, 340, 400 ActionDest: 895 Annotation: Subtype: Link Rect: 343, 389, 362, 400 ActionDest: 895 Annotation: Subtype: Link Rect: 514, 389, 546, 400 ActionDest: 933 Annotation: Subtype: Link Rect: 303, 378, 322, 388 ActionDest: 933 Annotation: Subtype: Link Rect: 324, 378, 343, 388 ActionDest: 933 Annotation: Subtype: Link Rect: 493, 341, 544, 352 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 329, 322, 340 ActionDest: 895 Annotation: Subtype: Link Rect: 327, 329, 397, 340 ActionDest: 895 Annotation: Subtype: Link Rect: 402, 329, 422, 340 ActionDest: 895 Annotation: Subtype: Link Rect: 427, 329, 475, 340 ActionDest: 895 Annotation: Subtype: Link Rect: 480, 329, 499, 340 ActionDest: 895 Annotation: Subtype: Link Rect: 504, 329, 546, 340 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 317, 324, 328 ActionDest: 822 Annotation: Subtype: Link Rect: 328, 317, 347, 328 ActionDest: 822 Annotation: Subtype: Link Rect: 509, 246, 546, 257 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 234, 323, 245 ActionDest: 895 Annotation: Subtype: Link Rect: 326, 234, 345, 245 ActionDest: 895 Annotation: Subtype: Link Rect: 348, 234, 424, 245 ActionDest: 933 Annotation: Subtype: Link Rect: 427, 234, 447, 245 ActionDest: 933 Annotation: Subtype: Link Rect: 450, 234, 497, 245 ActionDest: 895 Annotation: Subtype: Link Rect: 500, 234, 520, 245 ActionDest: 895 Annotation: Subtype: Link Rect: 523, 234, 546, 245 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 223, 322, 233 ActionDest: 895 Annotation: Subtype: Link Rect: 324, 223, 343, 233 ActionDest: 895 Annotation: Subtype: Link Rect: 345, 223, 403, 233 ActionDest: 822 Annotation: Subtype: Link Rect: 405, 223, 425, 233 ActionDest: 822 Annotation: Subtype: Link Rect: 306, 163, 356, 174 ActionDest: 933 Annotation: Subtype: Link Rect: 362, 163, 381, 174 ActionDest: 933 Annotation: Subtype: Link Rect: 387, 163, 436, 174 ActionDest: 822 Annotation: Subtype: Link Rect: 442, 163, 461, 174 ActionDest: 822 Annotation: Subtype: Link Rect: 458, 151, 475, 162 ActionDest: 933 Annotation: Subtype: Link Rect: 477, 151, 497, 162 ActionDest: 933 Annotation: Subtype: Link Rect: 443, 115, 460, 126 ActionDest: 933 Annotation: Subtype: Link Rect: 465, 115, 484, 126 ActionDest: 933 Annotation: Subtype: Link Rect: 516, 80, 546, 91 ActionDest: 933 Annotation: Subtype: Link Rect: 303, 68, 373, 79 ActionDest: 933 Annotation: Subtype: Link Rect: 375, 68, 394, 79 ActionDest: 933 Annotation: Subtype: Link Rect: 396, 68, 457, 79 ActionDest: 895 Annotation: Subtype: Link Rect: 459, 68, 478, 79 ActionDest: 895 Annotation: Subtype: Link Rect: 480, 68, 523, 79 ActionDest: 822 Annotation: Subtype: Link Rect: 525, 68, 544, 79 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 57, 347, 67 ActionDest: 895 Annotation: Subtype: Link Rect: 349, 57, 368, 67 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 170, 605, 227, 615 ActionDest: 822 Annotation: Subtype: Link Rect: 231, 605, 250, 615 ActionDest: 822 Annotation: Subtype: Link Rect: 254, 605, 273, 615 ActionDest: 822 Annotation: Subtype: Link Rect: 190, 520, 224, 531 ActionDest: 314 Annotation: Subtype: Link Rect: 145, 245, 181, 256 ActionDest: 314 Annotation: Subtype: Link Rect: 234, 90, 291, 101 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 79, 92, 89 ActionDest: 933 Annotation: Subtype: Link Rect: 95, 79, 114, 89 ActionDest: 933 Annotation: Subtype: Link Rect: 306, 680, 352, 691 ActionDest: 933 Annotation: Subtype: Link Rect: 354, 680, 374, 691 ActionDest: 933 Annotation: Subtype: Link Rect: 499, 573, 544, 583 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 561, 322, 572 ActionDest: 895 Annotation: Subtype: Link Rect: 306, 526, 348, 536 ActionDest: 822 Annotation: Subtype: Link Rect: 350, 526, 369, 536 ActionDest: 822 Annotation: Subtype: Link Rect: 306, 477, 380, 488 ActionDest: 822 Annotation: Subtype: Link Rect: 383, 477, 402, 488 ActionDest: 822 Annotation: Subtype: Link Rect: 347, 418, 418, 429 ActionDest: 822 Annotation: Subtype: Link Rect: 421, 418, 440, 429 ActionDest: 822 Annotation: Subtype: Link Rect: 306, 395, 363, 405 ActionDest: 895 Annotation: Subtype: Link Rect: 365, 395, 384, 405 ActionDest: 895 Annotation: Subtype: Link Rect: 409, 323, 442, 333 ActionDest: 314 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 147, 610, 200, 621 ActionDest: 895 Annotation: Subtype: Link Rect: 204, 610, 223, 621 ActionDest: 895 Annotation: Subtype: Link Rect: 227, 610, 291, 621 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 599, 67, 609 ActionDest: 822 Annotation: Subtype: Link Rect: 69, 599, 88, 609 ActionDest: 822 Annotation: Subtype: Link Rect: 90, 599, 168, 609 ActionDest: 895 Annotation: Subtype: Link Rect: 169, 599, 189, 609 ActionDest: 895 Annotation: Subtype: Link Rect: 51, 466, 112, 476 ActionDest: 895 Annotation: Subtype: Link Rect: 115, 466, 134, 476 ActionDest: 895 Annotation: Subtype: Link Rect: 243, 405, 291, 416 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 393, 74, 404 ActionDest: 933 Annotation: Subtype: Link Rect: 80, 393, 100, 404 ActionDest: 933 Annotation: Subtype: Link Rect: 195, 381, 253, 392 ActionDest: 895 Annotation: Subtype: Link Rect: 255, 381, 275, 392 ActionDest: 895 Annotation: Subtype: Link Rect: 203, 321, 242, 332 ActionDest: 822 Annotation: Subtype: Link Rect: 246, 321, 265, 332 ActionDest: 822 Annotation: Subtype: Link Rect: 539, 552, 544, 563 ActionDest: 370 Annotation: Subtype: Link Rect: 396, 540, 402, 551 ActionDest: 370 Annotation: Subtype: Link Rect: 337, 529, 343, 539 ActionDest: 370 Annotation: Subtype: Link Rect: 306, 314, 351, 324 ActionDest: 822 Annotation: Subtype: Link Rect: 354, 314, 373, 324 ActionDest: 822 Annotation: Subtype: Link Rect: 490, 254, 544, 265 ActionDest: 933 Annotation: Subtype: Link Rect: 303, 243, 322, 253 ActionDest: 933 Annotation: Subtype: Link Rect: 325, 243, 370, 253 ActionDest: 895 Annotation: Subtype: Link Rect: 373, 243, 392, 253 ActionDest: 895 Annotation: Subtype: Link Rect: 395, 243, 414, 253 ActionDest: 895 Annotation: Subtype: Link Rect: 417, 243, 436, 253 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 206, 349, 217 ActionDest: 895 Annotation: Subtype: Link Rect: 354, 206, 373, 217 ActionDest: 895 Annotation: Subtype: Link Rect: 337, 183, 381, 193 ActionDest: 895 Annotation: Subtype: Link Rect: 383, 183, 403, 193 ActionDest: 895 Annotation: Subtype: Link Rect: 314, 89, 429, 103 Annotation: Subtype: Link Rect: 315, 77, 429, 91 Annotation: Subtype: Link Rect: 315, 66, 426, 79 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 119, 755, 194, 765 ActionDest: 933 Annotation: Subtype: Link Rect: 198, 755, 218, 765 ActionDest: 933 Annotation: Subtype: Link Rect: 201, 731, 252, 741 ActionDest: 895 Annotation: Subtype: Link Rect: 254, 731, 274, 741 ActionDest: 895 Annotation: Subtype: Link Rect: 276, 731, 291, 741 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 719, 67, 729 ActionDest: 895 Annotation: Subtype: Link Rect: 69, 719, 89, 729 ActionDest: 895 Annotation: Subtype: Link Rect: 124, 695, 158, 706 ActionDest: 467 Annotation: Subtype: Link Rect: 161, 695, 214, 706 ActionDest: 895 Annotation: Subtype: Link Rect: 218, 695, 237, 706 ActionDest: 895 Annotation: Subtype: Link Rect: 240, 695, 246, 706 ActionDest: 425 Annotation: Subtype: Link Rect: 104, 587, 137, 598 ActionDest: 467 Annotation: Subtype: Link Rect: 60, 76, 291, 88 Annotation: Subtype: Link Rect: 48, 66, 196, 75 Annotation: Subtype: Link Rect: 360, 560, 416, 571 ActionDest: 933 Annotation: Subtype: Link Rect: 419, 560, 439, 571 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 138, 338, 197, 346 ActionDest: 933 Annotation: Subtype: Link Rect: 198, 338, 215, 346 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 238, 77, 248 ActionDest: 496 Annotation: Subtype: Link Rect: 98, 202, 128, 213 ActionDest: 496 Annotation: Subtype: Link Rect: 239, 154, 268, 165 ActionDest: 496 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 48, 621, 83, 632 ActionDest: 541 Annotation: Subtype: Link Rect: 463, 695, 496, 706 ActionDest: 639 Annotation: Subtype: Link Rect: 381, 261, 416, 271 ActionDest: 673 Annotation: Subtype: Link Rect: 303, 213, 336, 224 ActionDest: 673 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 79, 234, 156, 245 ActionDest: 822 Annotation: Subtype: Link Rect: 160, 234, 179, 245 ActionDest: 822 Annotation: Subtype: Link Rect: 125, 163, 178, 173 ActionDest: 822 Annotation: Subtype: Link Rect: 183, 163, 202, 173 ActionDest: 822 Annotation: Subtype: Link Rect: 207, 163, 289, 173 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 151, 67, 161 ActionDest: 895 Annotation: Subtype: Link Rect: 72, 151, 115, 161 ActionDest: 822 Annotation: Subtype: Link Rect: 120, 151, 140, 161 ActionDest: 822 Annotation: Subtype: Link Rect: 306, 356, 364, 367 ActionDest: 822 Annotation: Subtype: Link Rect: 368, 356, 387, 367 ActionDest: 822 Annotation: Subtype: Link Rect: 392, 356, 440, 367 ActionDest: 895 Annotation: Subtype: Link Rect: 445, 356, 464, 367 ActionDest: 895 Annotation: Subtype: Link Rect: 369, 297, 405, 307 ActionDest: 822 Annotation: Subtype: Link Rect: 409, 297, 428, 307 ActionDest: 822 Annotation: Subtype: Link Rect: 432, 297, 507, 307 ActionDest: 822 Annotation: Subtype: Link Rect: 511, 297, 530, 307 ActionDest: 822 Annotation: Subtype: Link Rect: 483, 285, 546, 295 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 273, 324, 283 ActionDest: 822 Annotation: Subtype: Link Rect: 328, 273, 348, 283 ActionDest: 822 Annotation: Subtype: Link Rect: 503, 225, 544, 236 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 213, 322, 224 ActionDest: 822 Annotation: Subtype: Link Rect: 516, 177, 546, 188 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 166, 322, 176 ActionDest: 895 Annotation: Subtype: Link Rect: 324, 166, 343, 176 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 96, 731, 148, 741 ActionDest: 895 Annotation: Subtype: Link Rect: 152, 731, 171, 741 ActionDest: 895 Annotation: Subtype: Link Rect: 99, 683, 130, 694 ActionDest: 895 Annotation: Subtype: Link Rect: 135, 683, 154, 694 ActionDest: 895 Annotation: Subtype: Link Rect: 92, 588, 118, 598 ActionDest: 895 Annotation: Subtype: Link Rect: 120, 588, 140, 598 ActionDest: 895 Annotation: Subtype: Link Rect: 200, 540, 251, 551 ActionDest: 895 Annotation: Subtype: Link Rect: 255, 540, 274, 551 ActionDest: 895 Annotation: Subtype: Link Rect: 143, 516, 183, 528 ActionDest: 822 Annotation: Subtype: Link Rect: 185, 516, 205, 528 ActionDest: 822 Annotation: Subtype: Link Rect: 165, 492, 264, 503 ActionDest: 822 Annotation: Subtype: Link Rect: 266, 492, 286, 503 ActionDest: 822 Annotation: Subtype: Link Rect: 408, 695, 453, 705 ActionDest: 933 Annotation: Subtype: Link Rect: 455, 695, 474, 705 ActionDest: 933 Annotation: Subtype: Link Rect: 400, 671, 446, 681 ActionDest: 822 Annotation: Subtype: Link Rect: 448, 671, 467, 681 ActionDest: 822 Annotation: Subtype: Link Rect: 469, 671, 523, 681 ActionDest: 822 Annotation: Subtype: Link Rect: 525, 671, 544, 681 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 659, 341, 669 ActionDest: 933 Annotation: Subtype: Link Rect: 343, 659, 363, 669 ActionDest: 933 Annotation: Subtype: Link Rect: 369, 659, 406, 669 ActionDest: 933 Annotation: Subtype: Link Rect: 410, 659, 430, 669 ActionDest: 933 Annotation: Subtype: Link Rect: 411, 623, 449, 633 ActionDest: 933 Annotation: Subtype: Link Rect: 451, 623, 471, 633 ActionDest: 933 Annotation: Subtype: Link Rect: 306, 611, 354, 621 ActionDest: 895 Annotation: Subtype: Link Rect: 356, 611, 375, 621 ActionDest: 895 Annotation: Subtype: Link Rect: 496, 611, 544, 621 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 599, 322, 609 ActionDest: 895 Annotation: Subtype: Link Rect: 326, 599, 366, 609 ActionDest: 933 Annotation: Subtype: Link Rect: 370, 599, 390, 609 ActionDest: 933 Annotation: Subtype: Link Rect: 405, 587, 484, 597 ActionDest: 895 Annotation: Subtype: Link Rect: 488, 587, 507, 597 ActionDest: 895 Annotation: Subtype: Link Rect: 510, 587, 546, 597 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 575, 322, 585 ActionDest: 822 Annotation: Subtype: Link Rect: 325, 575, 344, 585 ActionDest: 822 Annotation: Subtype: Link Rect: 499, 270, 546, 281 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 258, 342, 269 ActionDest: 895 Annotation: Subtype: Link Rect: 346, 258, 365, 269 ActionDest: 895 Annotation: Subtype: Link Rect: 452, 78, 490, 89 ActionDest: 895 Annotation: Subtype: Link Rect: 494, 78, 513, 89 ActionDest: 895 Annotation: Subtype: Link Rect: 516, 78, 546, 89 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 66, 324, 77 ActionDest: 822 Annotation: Subtype: Link Rect: 328, 66, 347, 77 ActionDest: 822 Annotation: Subtype: Link Rect: 352, 66, 400, 77 ActionDest: 822 Annotation: Subtype: Link Rect: 405, 66, 424, 77 ActionDest: 822 Annotation: Subtype: Link Rect: 428, 66, 467, 77 ActionDest: 895 Annotation: Subtype: Link Rect: 471, 66, 491, 77 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 175, 159, 225, 169 ActionDest: 822 Annotation: Subtype: Link Rect: 227, 159, 247, 169 ActionDest: 822 Annotation: Subtype: Link Rect: 165, 132, 215, 143 ActionDest: 895 Annotation: Subtype: Link Rect: 218, 132, 237, 143 ActionDest: 895 Annotation: Subtype: Link Rect: 220, 92, 268, 103 ActionDest: 895 Annotation: Subtype: Link Rect: 270, 92, 289, 103 ActionDest: 895 Annotation: Subtype: Link Rect: 48, 79, 109, 90 ActionDest: 822 Annotation: Subtype: Link Rect: 111, 79, 131, 90 ActionDest: 822 Annotation: Subtype: Link Rect: 133, 79, 235, 90 ActionDest: 933 Annotation: Subtype: Link Rect: 237, 79, 256, 90 ActionDest: 933 Annotation: Subtype: Link Rect: 505, 132, 544, 143 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 120, 322, 130 ActionDest: 895 Annotation: Subtype: Link Rect: 516, 106, 546, 117 ActionDest: 895 Annotation: Subtype: Link Rect: 303, 93, 325, 104 ActionDest: 895 Annotation: Subtype: Link Rect: 330, 93, 349, 104 ActionDest: 895 Annotation: Subtype: Link Rect: 526, 93, 546, 104 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 79, 323, 90 ActionDest: 822 Annotation: Subtype: Link Rect: 327, 79, 346, 90 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 253, 754, 291, 765 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 742, 96, 753 ActionDest: 822 Annotation: Subtype: Link Rect: 99, 742, 119, 753 ActionDest: 822 Annotation: Subtype: Link Rect: 177, 730, 220, 741 ActionDest: 822 Annotation: Subtype: Link Rect: 223, 730, 243, 741 ActionDest: 822 Annotation: Subtype: Link Rect: 141, 573, 180, 584 ActionDest: 822 Annotation: Subtype: Link Rect: 182, 573, 202, 584 ActionDest: 822 Annotation: Subtype: Link Rect: 136, 548, 182, 559 ActionDest: 822 Annotation: Subtype: Link Rect: 187, 548, 206, 559 ActionDest: 822 Annotation: Subtype: Link Rect: 268, 512, 291, 523 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 500, 68, 511 ActionDest: 822 Annotation: Subtype: Link Rect: 72, 500, 91, 511 ActionDest: 822 Annotation: Subtype: Link Rect: 151, 476, 196, 487 ActionDest: 895 Annotation: Subtype: Link Rect: 201, 476, 221, 487 ActionDest: 895 Annotation: Subtype: Link Rect: 172, 439, 214, 450 ActionDest: 895 Annotation: Subtype: Link Rect: 217, 439, 236, 450 ActionDest: 895 Annotation: Subtype: Link Rect: 241, 439, 291, 450 ActionDest: 822 Annotation: Subtype: Link Rect: 51, 427, 70, 438 ActionDest: 822 Annotation: Subtype: Link Rect: 51, 380, 104, 390 ActionDest: 822 Annotation: Subtype: Link Rect: 107, 380, 127, 390 ActionDest: 822 Annotation: Subtype: Link Rect: 82, 331, 135, 341 ActionDest: 895 Annotation: Subtype: Link Rect: 137, 331, 157, 341 ActionDest: 895 Annotation: Subtype: Link Rect: 276, 318, 291, 329 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 306, 108, 317 ActionDest: 933 Annotation: Subtype: Link Rect: 112, 306, 131, 317 ActionDest: 933 Annotation: Subtype: Link Rect: 190, 294, 264, 305 ActionDest: 933 Annotation: Subtype: Link Rect: 266, 294, 286, 305 ActionDest: 933 Annotation: Subtype: Link Rect: 375, 595, 427, 606 ActionDest: 895 Annotation: Subtype: Link Rect: 431, 595, 451, 606 ActionDest: 895 Annotation: Subtype: Link Rect: 455, 595, 544, 606 ActionDest: 822 Annotation: Subtype: Link Rect: 303, 583, 322, 593 ActionDest: 822 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 234, 175, 291, 185 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 163, 92, 173 ActionDest: 933 Annotation: Subtype: Link Rect: 95, 163, 114, 173 ActionDest: 933 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 211, 720, 291, 728 Annotation: Subtype: Link Rect: 57, 712, 64, 719 Annotation: Subtype: Link Rect: 240, 683, 291, 692 Annotation: Subtype: Link Rect: 57, 677, 104, 683 Annotation: Subtype: Link Rect: 220, 647, 291, 656 Annotation: Subtype: Link Rect: 57, 641, 71, 647 Annotation: Subtype: Link Rect: 175, 611, 244, 620 Annotation: Subtype: Link Rect: 188, 583, 291, 592 Annotation: Subtype: Link Rect: 57, 577, 55, 584 Annotation: Subtype: Link Rect: 80, 547, 179, 556 Annotation: Subtype: Link Rect: 164, 519, 251, 528 Annotation: Subtype: Link Rect: 248, 500, 291, 508 Annotation: Subtype: Link Rect: 57, 492, 115, 500 Annotation: Subtype: Link Rect: 86, 464, 180, 473 Annotation: Subtype: Link Rect: 160, 436, 231, 445 Annotation: Subtype: Link Rect: 251, 408, 291, 417 Annotation: Subtype: Link Rect: 57, 400, 98, 409 Annotation: Subtype: Link Rect: 144, 372, 244, 381 Annotation: Subtype: Link Rect: 133, 344, 220, 353 Annotation: Subtype: Link Rect: 197, 316, 291, 325 Annotation: Subtype: Link Rect: 57, 310, 71, 317 Annotation: Subtype: Link Rect: 278, 280, 291, 289 Annotation: Subtype: Link Rect: 57, 273, 151, 281 Annotation: Subtype: Link Rect: 117, 253, 291, 261 Annotation: Subtype: Link Rect: 57, 245, 201, 253 Annotation: Subtype: Link Rect: 232, 217, 291, 226 Annotation: Subtype: Link Rect: 57, 210, 84, 217 Annotation: Subtype: Link Rect: 163, 181, 273, 190 Annotation: Subtype: Link Rect: 237, 153, 291, 162 Annotation: Subtype: Link Rect: 57, 147, 104, 153 Annotation: Subtype: Link Rect: 49, 119, 142, 126 Annotation: Subtype: Link Rect: 167, 99, 258, 106 Annotation: Subtype: Link Rect: 533, 727, 546, 736 Annotation: Subtype: Link Rect: 312, 719, 381, 728 Annotation: Subtype: Link Rect: 304, 683, 414, 692 Annotation: Subtype: Link Rect: 491, 663, 546, 672 Annotation: Subtype: Link Rect: 312, 657, 326, 663 Annotation: Subtype: Link Rect: 427, 627, 500, 636 Annotation: Subtype: Link Rect: 401, 599, 492, 608 Annotation: Subtype: Link Rect: 477, 572, 546, 580 Annotation: Subtype: Link Rect: 312, 565, 319, 572 Annotation: Subtype: Link Rect: 421, 500, 528, 508 Annotation: Subtype: Link Rect: 331, 473, 433, 481 Annotation: Subtype: Link Rect: 422, 436, 508, 445 Annotation: Subtype: Link Rect: 416, 408, 481, 417 Annotation: Subtype: Link Rect: 387, 380, 473, 389 Annotation: Subtype: Link Rect: 395, 360, 505, 369 Annotation: Subtype: Link Rect: 533, 332, 546, 341 Annotation: Subtype: Link Rect: 312, 325, 396, 333 Annotation: Subtype: Link Rect: 329, 288, 415, 297 Annotation: Subtype: Link Rect: 304, 269, 397, 277 Annotation: Subtype: Link Rect: 304, 233, 372, 241 Annotation: Subtype: Link Rect: 304, 213, 435, 222 Annotation: Subtype: Link Rect: 489, 185, 546, 194 Annotation: Subtype: Link Rect: 312, 178, 326, 185 Annotation: Subtype: Link Rect: 472, 149, 546, 158 Annotation: Subtype: Link Rect: 312, 142, 326, 149 Annotation: Subtype: Link Rect: 494, 113, 546, 122 Annotation: Subtype: Link Rect: 312, 107, 360, 113 Annotation: Subtype: Link Rect: 421, 77, 510, 86 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 113, 740, 195, 748 Annotation: Subtype: Link Rect: 230, 711, 291, 720 Annotation: Subtype: Link Rect: 57, 705, 73, 711 Annotation: Subtype: Link Rect: 222, 675, 291, 684 Annotation: Subtype: Link Rect: 57, 668, 101, 675 Annotation: Subtype: Link Rect: 127, 631, 232, 640 Annotation: Subtype: Link Rect: 172, 603, 281, 612 Annotation: Subtype: Link Rect: 117, 576, 209, 584 Annotation: Subtype: Link Rect: 126, 540, 240, 549 Annotation: Subtype: Link Rect: 138, 512, 215, 521 Annotation: Subtype: Link Rect: 204, 492, 275, 501 Annotation: Subtype: Link Rect: 172, 464, 262, 473 Annotation: Subtype: Link Rect: 49, 436, 155, 445 Annotation: Subtype: Link Rect: 115, 408, 204, 417 Annotation: Subtype: Link Rect: 253, 388, 291, 397 Annotation: Subtype: Link Rect: 57, 381, 106, 389 Annotation: Subtype: Link Rect: 138, 352, 250, 361 Annotation: Subtype: Link Rect: 192, 325, 254, 333 Annotation: Subtype: Link Rect: 83, 289, 180, 298 Annotation: Subtype: Link Rect: 76, 261, 174, 270 Annotation: Subtype: Link Rect: 190, 234, 268, 242 Annotation: Subtype: Link Rect: 87, 197, 186, 206 Annotation: Subtype: Link Rect: 76, 170, 157, 178 Annotation: Subtype: Link Rect: 169, 141, 233, 150 Annotation: Subtype: Link Rect: 230, 113, 291, 122 Annotation: Subtype: Link Rect: 57, 107, 108, 114 Annotation: Subtype: Link Rect: 69, 71, 166, 78 Annotation: Subtype: Link Rect: 432, 739, 521, 748 Annotation: Subtype: Link Rect: 462, 719, 546, 728 Annotation: Subtype: Link Rect: 312, 713, 316, 719 Annotation: Subtype: Link Rect: 446, 683, 546, 692 Annotation: Subtype: Link Rect: 312, 677, 316, 683 Annotation: Subtype: Link Rect: 415, 647, 525, 656 Annotation: Subtype: Link Rect: 409, 619, 519, 628 Annotation: Subtype: Link Rect: 331, 592, 441, 600 Annotation: Subtype: Link Rect: 304, 564, 401, 572 Annotation: Subtype: Link Rect: 523, 544, 546, 553 Annotation: Subtype: Link Rect: 312, 537, 353, 545 Annotation: Subtype: Link Rect: 479, 508, 546, 517 Annotation: Subtype: Link Rect: 312, 502, 319, 508 Annotation: Subtype: Link Rect: 473, 472, 546, 481 Annotation: Subtype: Link Rect: 312, 466, 324, 472 Annotation: Subtype: Link Rect: 507, 436, 546, 445 Annotation: Subtype: Link Rect: 312, 428, 378, 436 Annotation: Subtype: Link Rect: 523, 400, 546, 409 Annotation: Subtype: Link Rect: 312, 393, 398, 401 Annotation: Subtype: Link Rect: 367, 356, 459, 365 Annotation: Subtype: Link Rect: 432, 328, 490, 337 Annotation: Subtype: Link Rect: 304, 293, 381, 302 Annotation: Subtype: Link Rect: 331, 265, 413, 274 Annotation: Subtype: Link Rect: 411, 245, 486, 254 Annotation: Subtype: Link Rect: 484, 217, 546, 226 Annotation: Subtype: Link Rect: 312, 210, 339, 217 Annotation: Subtype: Link Rect: 397, 181, 515, 190 Annotation: Subtype: Link Rect: 470, 161, 535, 170 Annotation: Subtype: Link Rect: 466, 141, 546, 150 Annotation: Subtype: Link Rect: 312, 135, 316, 141 Annotation: Subtype: Link Rect: 479, 105, 546, 114 Annotation: Subtype: Link Rect: 312, 99, 319, 106 Annotation: Subtype: Link Rect: 393, 69, 458, 78 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 453, 799, 546, 807 Annotation: Subtype: Link Rect: 173, 739, 243, 748 Annotation: Subtype: Link Rect: 82, 712, 189, 720 Annotation: Subtype: Link Rect: 245, 683, 291, 692 Annotation: Subtype: Link Rect: 57, 677, 82, 683 Annotation: Subtype: Link Rect: 235, 654, 291, 663 Annotation: Subtype: Link Rect: 57, 648, 104, 655 Annotation: Subtype: Link Rect: 49, 618, 163, 626 Annotation: Subtype: Link Rect: 49, 589, 159, 597 Annotation: Subtype: Link Rect: 228, 552, 291, 561 Annotation: Subtype: Link Rect: 57, 545, 64, 552 Annotation: Subtype: Link Rect: 127, 525, 219, 533 Annotation: Subtype: Link Rect: 170, 504, 256, 513 Annotation: Subtype: Link Rect: 450, 747, 532, 756 Annotation: Subtype: Link Rect: 331, 728, 424, 736 Annotation: Subtype: Link Rect: 341, 687, 427, 696 Annotation: Subtype: Link Rect: 337, 659, 426, 668 Annotation: Subtype: Link Rect: 486, 603, 546, 612 Annotation: Subtype: Link Rect: 312, 597, 319, 604 Annotation: Subtype: Link Rect: 388, 568, 475, 576 Annotation: Subtype: Link Rect: 445, 540, 546, 549 Annotation: Subtype: Link Rect: 312, 533, 319, 540 Annotation: Subtype: Link Rect: 374, 504, 436, 513 Annotation: Subtype: Link Rect: 48, 33, 133, 41 Annotation: Subtype: Link Rect: 498, 33, 546, 41 Checksum: aebfc726 Type: CRC32 Checksum: 74adcef856e507e82442a110d1b2ba97 Type: MD5 Checksum: bb66e0ed63df685e24623ba91850fed51ae2cf0b Type: SHA-1