4ffe3ed1fb73529f17604e9f0e78f644 pmc_10106835.pdf 84ab67693fc4e89e79fde8afe971d5a7bedf63ea pmc_10106835.pdf 3923757270e7fab1e9f8068e6a0d327ec01253de2921c10428b79337c09d3e23 pmc_10106835.pdf Title: Gene dysregulation in acute HIV-1 infection – early transcriptomic analysis reveals the crucial biological functions affected Subject: Transcriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting damage to biological functions, especially in the immune system. Keywords: HIV, gene expression profiling, sub-Sahara Africa (SSA), Mozambique, acute HIV infection, host microbial interactions, innate immunity Author: Erica Parker CreationDate: Wed Mar 29 09:41:02 2023 CEST ModDate: Wed Mar 29 09:54:55 2023 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.389 x 841.663 pts Page rot: 0 File size: 10028853 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- BIPDLD+AdvTTd3a5f740 Type 1C WinAnsi yes yes no 1149 0 BIPDMD+AdvTTd3a5f740+20 Type 1C WinAnsi yes yes no 1150 0 BIPDME+AdvPSA18C Type 1C WinAnsi yes yes no 1151 0 BIPDMF+AdvTT9b12cd41 Type 1C WinAnsi yes yes no 1152 0 BIPDMG+AdvTT9b12cd41+20 Type 1C WinAnsi yes yes no 1153 0 BIPDMH+AdvPSA323 Type 1C WinAnsi yes yes no 1154 0 BIPDMI+AdvTT2c8ce45a Type 1C WinAnsi yes yes no 1155 0 BIPDMJ+AdvTT9b12cd41+fb Type 1C Custom yes yes yes 1156 0 BIPGLI+AdvTTd168d80a.I Type 1C WinAnsi yes yes no 1170 0 BIPGPK+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 413 0 BIPHAK+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 421 0 BIPGPI+AdvTT2c8ce45a+fb Type 1C Custom yes yes yes 415 0 BIPGPJ+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 419 0 BIPHBL+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 434 0 BIPHBM+AdvTT58d178b9+03 Type 1C Custom yes yes yes 426 0 BIPHCN+AdvOT3f84ef53 Type 1C WinAnsi yes yes no 427 0 BIPHCO+AdvOT1ef757c0+22 Type 1C Custom yes yes yes 430 0 BIPHEO+AdvOT1ef757c0+01 Type 1C Custom yes yes yes 438 0 BIPNCL+AdvOT46dcae81 Type 1C WinAnsi yes yes no 441 0 BIPNCM+AdvOT7d6df7ab.I+fb Type 1C Custom yes yes yes 443 0 BIPNEM+AdvOT46dcae81+fb Type 1C Custom yes yes yes 447 0 BIPNEN+AdvOTb65e897d.B Type 1C WinAnsi yes yes no 450 0 BJBGKC+HelveticaNeueLTStd-Bd Type 1C WinAnsi yes yes no 455 0 BJGPNA+AdvTTd3a5f740+fb Type 1C Custom yes yes yes 457 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-05 02:29:46 CEST RepresentationInformation: pmc_10106835.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-27 02:24:32 CEST Size: 10028853 Format: PDF Version: 1.4 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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Keywords: HIV, gene expression profiling, sub-Sahara Africa (SSA), Mozambique, acute HIV infection, host microbial interactions, innate immunity CreationDate: Wed Mar 29 09:41:02 CEST 2023 ModDate: Wed Mar 29 09:54:55 CEST 2023 ID: 0x2cf0e2977fad5694ae42f480975bd99e, 0x30acaf8a844afa41b24e0027e6f5a87a Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2919 ImageHeight: 577 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 3248 ImageHeight: 1223 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1848 ImageHeight: 1361 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2953 ImageHeight: 888 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: 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FontName: BIPDMD+AdvTTd3a5f740+20 Flags: Nonsymbolic FontBBox: -114, -166, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIPDME+AdvPSA18C FontSubset: true FirstChar: 180 LastChar: 180 FontDescriptor: FontName: BIPDME+AdvPSA18C Flags: Nonsymbolic FontBBox: -156, -208, 1125, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIPGPI+AdvTT2c8ce45a+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: BIPGPI+AdvTT2c8ce45a+fb Flags: Symbolic FontBBox: 0, 0, 947, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: BIPNEM+AdvOT46dcae81+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: BIPNEM+AdvOT46dcae81+fb Flags: Symbolic FontBBox: 0, 0, 739, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdf Erica Parker Melinda A. Judge Lucia Pastor Laura Fuente-Soro Chenjerai Jairoce Kim W. Carter Denise Anderson Inácio Mandomando Holly D. Clifford Denise Naniche Peter Neils Le Souëf Transcriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting damage to biological functions, especially in the immune system. Copyright © 2023 Parker, Judge, Pastor, Fuente-Soro, Jairoce, Carter, Anderson, Mandomando, Clifford, Naniche and Le Souëf. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Gene dysregulation in acute HIV-1 infection – early transcriptomic analysis reveals the crucial biological functions affected HIV gene expression profiling sub-Sahara Africa (SSA) Mozambique acute HIV infection host microbial interactions innate immunity HIV, gene expression profiling, sub-Sahara Africa (SSA), Mozambique, acute HIV infection, host microbial interactions, innate immunity True https://www.frontiersin.org/legal/copyright-statement 2023-03-29T15:54:55+08:00 2023-03-29T15:41:02+08:00 2023-03-29T15:54:55+08:00 uuid:6340532a-dfb3-47d0-9af5-a3cc2be6d8f6 uuid:645b20e7-5fa5-4970-83cd-02f8117a8fbe Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 222, 686, 544, 707 Annotation: Subtype: Link Rect: 222, 661, 516, 682 Annotation: Subtype: Link Rect: 222, 636, 469, 657 Annotation: Subtype: Link Rect: 222, 611, 486, 632 Annotation: Subtype: Link Rect: 49, 33, 202, 40 Annotation: Subtype: Link Rect: 500, 33, 545, 40 Annotation: Subtype: Link Rect: 49, 691, 125, 706 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