78d795fa282e09b6576707a3576509a6 pmc_10175281.pdf 80f218cd8ef46ef0fbe2660167aee5c934becd58 pmc_10175281.pdf aa7105d25c00772c18aa83b63518668dda01c96f419d89db329c81fe44a0ed28 pmc_10175281.pdf Title: An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization Subject: Scientific Data, doi:10.1038/s41597-023-02182-3 Keywords: Author: Florian Kromp Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu May 11 04:26:24 2023 CEST ModDate: Thu May 11 07:46:46 2023 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1110142 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-It Type 1C WinAnsi yes no yes 44 0 MinionPro-It Type 1C Custom yes no yes 45 0 MinionPro-Regular Type 1C Custom yes no yes 46 0 NWOESS+ArialUnicodeMS CID TrueType Identity-H yes yes yes 392 0 UJIRAC+Corbel-Bold2 Type 1C WinAnsi yes yes yes 47 0 OBPJGQ+Corbel-Bold CID TrueType Identity-H yes yes yes 48 0 EQDLMF+Corbel-BoldItalic Type 1C WinAnsi yes yes yes 393 0 PBQJMF+Corbel2 Type 1C WinAnsi yes yes yes 49 0 KSSQCY+Corbel CID TrueType Identity-H yes yes yes 50 0 PBQJMF+Corbel2 Type 1C WinAnsi yes yes yes 284 0 XJQAXY+Calibri Type 1C Custom yes yes no 59 0 EuclidSymbol Type 1C Custom yes no yes 60 0 MinionPro-Bold Type 1C Custom yes no yes 61 0 XJQAXY+Calibri-Bold Type 1C Custom yes yes no 62 0 Calibri-Bold2 Type 1C WinAnsi yes no no 119 0 Calibri2 Type 1C WinAnsi yes no no 120 0 Calibri4 Type 1C Custom yes no no 137 0 Calibri-Bold3 Type 1C WinAnsi yes no no 138 0 Calibri3 Type 1C WinAnsi yes no no 139 0 Calibri-Bold5 Type 1C WinAnsi yes no no 140 0 Calibri-Bold4 Type 1C WinAnsi yes no no 141 0 MNJDZU+TimesNewRomanPSMT Type 1C WinAnsi yes yes yes 205 0 EuclidSymbol-Italic Type 1C Custom yes no yes 206 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-09-01 08:22:28 CEST RepresentationInformation: pmc_10175281.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-07-06 02:32:15 CEST Size: 1110142 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 444 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization Children: Item: Title: Background & Summary Item: Title: Methods Children: Item: Title: Participants and ethics. Item: Title: Embryo development. Item: Title: Blastocyst imaging. Item: Title: Clinical annotations. Item: Title: Gardner score consortium annotation. Children: Item: Title: Gardner criteria. Item: Title: Consortium annotation. Item: Title: Refined consortium agreement. Item: Title: Data Records Children: Item: Title: Deep learning model training. Item: Title: Technical Validation Children: Item: Title: Inter-annotator agreement. Item: Title: Benchmark for deep learning models. Item: Title: Acknowledgements Item: Title: Fig. 1 Workflow of creating the silver-standard training set and the gold-standard test set involving the Gardner-expert and an international consortium consisting of experienced clinical embryologists. Item: Title: Fig. 2 Class assignment distribution of the Gardner criteria within the silver-standard training set and the gold-standard test set. Item: Title: Fig. 3 Inter-Annotator agreement (a–c) and deep learning baseline agreement (d–f) with the consensus calculated using Cohen’s Kappa-score. Item: Title: Table 1 Parameters provided in the annotations files. Item: Title: Table 2 Mean value and standard deviation of the accuracy and the weighted class-average of precision, recall and F1-score of the expert embryologists remaining after consensus filtering, compared to the consensus vote. Info: Title: An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization Author: Florian Kromp Subject: Scientific Data, doi:10.1038/s41597-023-02182-3 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu May 11 04:56:24 CEST 2023 ModDate: Thu May 11 07:46:46 CEST 2023 ID: 0xd8d6cc53aceafe5d33f2df13be7e52b8, 0x8611d0762c8da6347707f22a08203bae Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1624 ImageHeight: 706 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: OBPJGQ+Corbel-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: KSSQCY+Corbel Encoding: Identity-H ToUnicode: true Font: BaseFont: NWOESS+ArialUnicodeMS Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: EQDLMF+Corbel-BoldItalic FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: EQDLMF+Corbel-BoldItalic Flags: Nonsymbolic, Italic FontBBox: -494, -239, 1194, 952 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Calibri4 FirstChar: 30 LastChar: 119 FontDescriptor: FontName: Calibri4 Flags: Nonsymbolic FontBBox: -503, -312, 1240, 1026 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: Calibri-Bold3 FirstChar: 69 LastChar: 88 FontDescriptor: FontName: Calibri-Bold3 Flags: Nonsymbolic FontBBox: -519, -349, 1263, 1039 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: Calibri3 FirstChar: 44 LastChar: 117 FontDescriptor: FontName: Calibri3 Flags: Nonsymbolic FontBBox: -503, -312, 1240, 1026 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Calibri-Bold5 FirstChar: 41 LastChar: 102 FontDescriptor: FontName: Calibri-Bold5 Flags: Nonsymbolic FontBBox: -519, -349, 1263, 1039 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MinionPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: Calibri-Bold4 FirstChar: 67 LastChar: 77 FontDescriptor: FontName: Calibri-Bold4 Flags: Nonsymbolic FontBBox: -519, -349, 1263, 1039 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MNJDZU+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: MNJDZU+TimesNewRomanPSMT Flags: Serif, Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: EuclidSymbol-Italic FirstChar: 0 LastChar: 255 FontDescriptor: FontName: EuclidSymbol-Italic Flags: Symbolic, Italic FontBBox: -166, -276, 1162, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: UJIRAC+Corbel-Bold2 FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: UJIRAC+Corbel-Bold2 Flags: Nonsymbolic FontBBox: -556, -239, 1155, 952 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: PBQJMF+Corbel2 FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: PBQJMF+Corbel2 Flags: Nonsymbolic FontBBox: -553, -239, 1110, 952 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Calibri-Bold2 FirstChar: 45 LastChar: 86 FontDescriptor: FontName: Calibri-Bold2 Flags: Nonsymbolic FontBBox: -519, -349, 1263, 1039 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: Calibri2 FirstChar: 32 LastChar: 89 FontDescriptor: FontName: Calibri2 Flags: Nonsymbolic FontBBox: -503, -312, 1240, 1026 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: XJQAXY+Calibri FontSubset: true FirstChar: 30 LastChar: 121 FontDescriptor: FontName: XJQAXY+Calibri Flags: Nonsymbolic FontBBox: -503, -312, 1240, 1026 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: EuclidSymbol FirstChar: 0 LastChar: 255 FontDescriptor: FontName: EuclidSymbol Flags: Symbolic FontBBox: -166, -253, 1090, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: XJQAXY+Calibri-Bold FontSubset: true FirstChar: 31 LastChar: 119 FontDescriptor: FontName: XJQAXY+Calibri-Bold Flags: Nonsymbolic FontBBox: -519, -349, 1263, 1039 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true CIDFontType2: Font: BaseFont: NWOESS+ArialUnicodeMS CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: NWOESS+ArialUnicodeMS Flags: Symbolic FontBBox: -1011, -330, 2260, 1078 FontFile2: true Font: BaseFont: KSSQCY+Corbel CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: KSSQCY+Corbel Flags: Symbolic FontBBox: -553, -239, 1110, 952 FontFile2: true Font: BaseFont: OBPJGQ+Corbel-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: OBPJGQ+Corbel-Bold Flags: Symbolic FontBBox: -556, -239, 1155, 952 FontFile2: true XMP: application/pdf doi:10.1038/s41597-023-02182-3 Springer US Scientific Data, doi:10.1038/s41597-023-02182-3 An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization Florian Kromp Raphael Wagner Basak Balaban Vamp#x000E9;ronique Cottin Irene Cuevas-Saiz Clara Schachner Peter Fancsovits Mohamed Fawzy Lukas Fischer Necati Findikli Borut Kovaamp#x0010D;iamp#x0010D; Dejan Ljiljak Iris Martamp#x000ED;nez-Rodero Lodovico Parmegiani Omar Shebl Xie Min Thomas Ebner Springer 2023-05-11T07:46:46+02:00 2023-05-11T07:56:24+05:30 2023-05-11T07:46:46+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) uuid:7583e3c3-6709-4aae-9777-994db991673a uuid:d333b49a-b5f2-4d9e-8cec-e5345825ed0c default 1 converted uuid:fbb310a3-1994-4790-82fa-d068a2e85443 converted to PDF/A-2b pdfToolbox 2023-05-11T07:57:13+05:30 2 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 217, 509, 226, 495 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 535, 496, 544, 484 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 549, 247, 552, 235 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 433, 227, 436, 215 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 437, 227, 440, 215 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 236, 207, 238, 195 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 383, 207, 386, 195 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 218, 54, 299, 42 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 481, 655, 556, 637 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 345, 734, 348, 722 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 182, 624, 185, 612 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 435, 624, 438, 612 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 177, 604, 180, 592 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 327, 564, 330, 552 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 333, 564, 338, 552 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 352, 544, 357, 532 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 359, 544, 364, 532 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 366, 544, 371, 532 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 480, 534, 486, 522 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 271, 504, 276, 492 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 335, 494, 340, 482 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 362, 484, 368, 472 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 412, 484, 418, 472 Flags: Print AppearanceDictionary: true Destination: 215 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 229, 288, 217 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 276, 179, 374, 167 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 528, 366, 554, 353 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 356, 209, 343 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 334, 336, 338, 323 Flags: Print AppearanceDictionary: true Destination: 52 Annotation: Subtype: Link Rect: 420, 306, 425, 294 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 262, 246, 267, 234 Flags: Print AppearanceDictionary: true Destination: 72 Annotation: Subtype: Link Rect: 180, 207, 186, 195 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 524, 207, 530, 195 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 531, 207, 537, 195 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 352, 197, 357, 185 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 424, 197, 430, 185 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 373, 177, 379, 165 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 380, 177, 386, 165 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 546, 167, 552, 155 Flags: Print AppearanceDictionary: true Destination: 215 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 548, 80, 552, 68 Flags: Print AppearanceDictionary: true Destination: 85 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 174, 514, 180, 502 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 213, 514, 217, 502 Flags: Print AppearanceDictionary: true Destination: 128 Annotation: Subtype: Link Rect: 493, 494, 499, 482 Flags: Print AppearanceDictionary: true Destination: 215 Annotation: Subtype: Link Rect: 366, 464, 371, 452 Flags: Print AppearanceDictionary: true Destination: 128 Annotation: Subtype: Link Rect: 486, 366, 490, 354 Flags: Print AppearanceDictionary: true Destination: 155 Annotation: Subtype: Link Rect: 503, 284, 554, 272 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 274, 386, 262 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 262, 205, 379, 195 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 459, 197, 554, 186 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 188, 218, 178 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 456, 171, 554, 161 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 162, 211, 152 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 272, 129, 387, 118 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 383, 112, 526, 101 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 196, 94, 336, 84 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 214, 78, 332, 67 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 296, 61, 404, 50 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 206, 25, 353, 16 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 219, 726, 359, 716 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 207, 709, 317, 699 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 399, 692, 518, 682 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 253, 675, 407, 665 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 267, 658, 403, 648 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 310, 641, 451, 631 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 229, 624, 361, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 332, 607, 472, 597 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 264, 590, 380, 580 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 520, 582, 554, 571 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 573, 258, 563 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 521, 556, 554, 546 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 547, 255, 537 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 229, 530, 375, 520 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 275, 513, 387, 503 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 476, 505, 554, 495 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 496, 233, 486 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 416, 463, 512, 452 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 349, 185, 441, 172 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 344, 75, 504, 63 Flags: Print AppearanceDictionary: true Thumb: true Checksum: fcce5052 Type: CRC32 Checksum: 78d795fa282e09b6576707a3576509a6 Type: MD5 Checksum: 80f218cd8ef46ef0fbe2660167aee5c934becd58 Type: SHA-1 Checksum: aa7105d25c00772c18aa83b63518668dda01c96f419d89db329c81fe44a0ed28 Type: SHA-256