626e840b6ec568701a252f7a5c45b411 pmc_10184782.pdf f1ad3fee24490107203b56b5a12074a1cc7947dc pmc_10184782.pdf c5910c9262babc1ea009cf07c13b9bef52d11ea7ae854ad28ed5125dbf8712de pmc_10184782.pdf Title: The contribution of historical processes to contemporary extinction risk in placental mammals Author: Aryn P. Wilder, Megan A Supple, Ayshwarya Subramanian, Anish Mudide, Ross Swofford, Aitor Serres-Armero, Cynthia Steiner, Klaus-Peter Koepfli, Diane P. Genereux, Elinor K. Karlsson, Kerstin Lindblad-Toh, Tomas Marques-Bonet, Violeta Munoz Fuentes, Kathleen Foley, Wynn K. Meyer, Zoonomia Consortium, Oliver A. Ryder, Beth Shapiro Creator: Antenna House Formatter V7.3 MR1 Linux : 7.3.2.60453 (2023-03-06T13:41+09) Producer: Antenna House PDF Output Library 7.3.1863 CreationDate: Mon May 15 21:11:56 2023 CEST ModDate: Mon May 15 21:11:56 2023 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 20 Encrypted: no Page size: 612 x 792 pts (letter) Page rot: 0 File size: 966177 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- Times-Roman Type 1 Custom no no yes 12 0 Helvetica Type 1 Custom no no yes 14 0 Helvetica-Bold Type 1 Standard no no no 199 0 Times-Bold Type 1 Standard no no no 803 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-01-11 02:29:46 CET RepresentationInformation: pmc_10184782.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-12-02 02:18:39 CET Size: 966177 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 105 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Item: Title: One-Sentence Summary: Item: Title: Historical population size is relevant to contemporary extinction risk Item: Title: Historically smaller populations carry proportionally larger burdens of genetic load Item: Title: Genomic information can help predict extinction risk Item: Title: Discussion Item: Title: Materials and Methods Children: Item: Title: Mammal genomes and metadata Item: Title: Estimating historical effective population sizes and genome-wide heterozygosity Item: Title: Deleterious genetic load Item: Title: Predicting threat from genomic variables Item: Title: References Item: Title: Fig. 1. Item: Title: Fig. 2. Item: Title: Fig. 3. 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Wilder, Megan A Supple, Ayshwarya Subramanian, Anish Mudide, Ross Swofford, Aitor Serres-Armero, Cynthia Steiner, Klaus-Peter Koepfli, Diane P. Genereux, Elinor K. Karlsson, Kerstin Lindblad-Toh, Tomas Marques-Bonet, Violeta Munoz Fuentes, Kathleen Foley, Wynn K. Meyer, Zoonomia Consortium, Oliver A. 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