a2150e454b06e8139d245a19f9678edb pmc_10215587.pdf e7b9c6f47e05a7fa58349cf3e2b1adc68ba3c53d pmc_10215587.pdf 6e02484055357d360eb2e57663edf074e8fc41c7596eec23f5047908e45e9f38 pmc_10215587.pdf Title: A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information: An Example with Two Iberian Varieties Subject: INGA FOOD, S.A. initiated a crossbreeding program between two Iberian pig varieties, Retinto (R) and Entrepelado (E), with the goal of producing a hybrid sow (F1). Several studies have been conducted to evaluate its productive performance, and these studies have revealed differences in litter size between the two reciprocal crosses, suggesting the presence of genomic imprinting effects. To further investigate these effects, this study introduces a multivariate gametic model designed to estimate gametic correlations between paternal and maternal effects originating from both genetic backgrounds involved in the reciprocal crosses. The dataset consisted of 1258 records (the total number born—TNB and the number born alive—NBA) from 203 crossbred dams for the Entrepelado (sire) Retinto (dam) cross and 700 records from 125 crossbred dams for the Retinto (sire) Entrepelado (dam) cross. All animals were genotyped using the GeneSeek® GPP Porcine 70 K HDchip (Illumina Inc., San Diego, CA, USA). The results indicated that the posterior distribution of the gametic correlation between paternal and maternal effects was distinctly different between the two populations. Specifically, in the Retinto population, the gametic correlation showed a positive skew with posterior probabilities of 0.78 for the TNB and 0.80 for the NBA. On the other hand, the Entrepelado population showed a posterior probability of a positive gametic correlation between paternal and maternal effects of approximately 0.50. The differences in the shape of the posterior distribution of the gametic correlations between paternal and maternal effects observed in the two varieties may account for the distinct performance outcomes observed in the reciprocal crosses. Keywords: gametic model; Iberian pig; crossbreeding; Retinto; Entrepelado Author: Houssemeddine Srihi, David López-Carbonell, Noelia Ibáñez-Escriche, Joaquim Casellas, Pilar Hernández, Sara Negro and Luis Varona Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue May 16 07:56:36 2023 CEST ModDate: Tue May 16 08:08:19 2023 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2036852 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ENXZUH+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 AWHDWW+VnURWPalladioL Type 1 Custom yes yes no 15 0 PNUZCK+URWPalladioL-Bold Type 1 Custom yes yes no 19 0 NTVWON+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 SXFZNR+URWPalladioL-Ital Type 1 Custom yes yes no 28 0 FWQCWQ+CMSY10 Type 1 Builtin yes yes no 32 0 SZMRXJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 50 0 FUPSPM+CMEX10 Type 1 Builtin yes yes no 75 0 FVXSCS+URWPalladioL-BoldItal Type 1 Custom yes yes no 79 0 GIGFZE+CMR10 Type 1 Builtin yes yes no 83 0 QQXUPP+PazoMath Type 1 Builtin yes yes no 90 0 SUZJEW+PazoMath-Italic Type 1 Builtin yes yes no 94 0 FOBMAM+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 108 0 FOBMAN+PalatinoLinotype CID TrueType Identity-H yes yes yes 111 0 FOBMAO+PalatinoLinotype TrueType WinAnsi yes yes no 117 0 FOBMCA+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 120 0 FOBOJC+PalatinoLinotype TrueType MacRoman yes yes no 123 0 FOBOKC+TimesNewRoman,Bold CID TrueType Identity-H yes yes yes 126 0 OMHGYV+PazoMath-BoldItalic Type 1 Builtin yes yes no 137 0 FOBMAM+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 144 0 FOBMAN+PalatinoLinotype CID TrueType Identity-H yes yes yes 147 0 FOBMAO+PalatinoLinotype TrueType WinAnsi yes yes no 153 0 FOBMCA+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 156 0 FOCCMK+CambriaMath CID TrueType Identity-H yes yes yes 159 0 FOBMAM+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 170 0 FOBMAN+PalatinoLinotype CID TrueType Identity-H yes yes yes 173 0 FOBMAO+PalatinoLinotype TrueType WinAnsi yes yes no 179 0 FOBMCA+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 182 0 FOCCMK+CambriaMath CID TrueType Identity-H yes yes yes 185 0 FOBMAM+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 199 0 FOBMAN+PalatinoLinotype CID TrueType Identity-H yes yes yes 202 0 FOBMAO+PalatinoLinotype TrueType WinAnsi yes yes no 208 0 FOBMCA+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 211 0 FOBOJC+PalatinoLinotype TrueType MacRoman yes yes no 214 0 NUUXUW+VnURWPalladioL-Italic Type 1 Custom yes yes no 221 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-06-30 02:35:43 CEST RepresentationInformation: pmc_10215587.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-06-22 02:22:45 CEST Size: 2036852 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 314 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Results and Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Info: Title: A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information: An Example with Two Iberian Varieties Author: Houssemeddine Srihi, David López-Carbonell, Noelia Ibáñez-Escriche, Joaquim Casellas, Pilar Hernández, Sara Negro and Luis Varona Subject: INGA FOOD, S.A. initiated a crossbreeding program between two Iberian pig varieties, Retinto (R) and Entrepelado (E), with the goal of producing a hybrid sow (F1). Several studies have been conducted to evaluate its productive performance, and these studies have revealed differences in litter size between the two reciprocal crosses, suggesting the presence of genomic imprinting effects. To further investigate these effects, this study introduces a multivariate gametic model designed to estimate gametic correlations between paternal and maternal effects originating from both genetic backgrounds involved in the reciprocal crosses. The dataset consisted of 1258 records (the total number born TNB and the number born alive NBA) from 203 crossbred dams for the Entrepelado (sire) Retinto (dam) cross and 700 records from 125 crossbred dams for the Retinto (sire) Entrepelado (dam) cross. All animals were genotyped using the GeneSeek® GPP Porcine 70 K HDchip (Illumina Inc., San Diego, CA, USA). The results indicated that the posterior distribution of the gametic correlation between paternal and maternal effects was distinctly different between the two populations. Specifically, in the Retinto population, the gametic correlation showed a positive skew with posterior probabilities of 0.78 for the TNB and 0.80 for the NBA. On the other hand, the Entrepelado population showed a posterior probability of a positive gametic correlation between paternal and maternal effects of approximately 0.50. The differences in the shape of the posterior distribution of the gametic correlations between paternal and maternal effects observed in the two varieties may account for the distinct performance outcomes observed in the reciprocal crosses. 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