16f206f3736acf61c61d40ff4d186dec pmc_10282840.pdf e10a33747ae70c848f3c2b282c2019e2e88428f6 pmc_10282840.pdf 6f6937fd501759ed77efd815ddcf362b2411ae48eccfbb32c557c16013942e70 pmc_10282840.pdf Title: Effect of a low versus intermediate tidal volume strategy on pulmonary complications in patients at risk of acute respiratory distress syndrome—a randomized clinical trial Subject: Introduction: There is no consensus on whether invasive ventilation should use low tidal volumes (VT) to prevent lung complications in patients at risk of acute respiratory distress syndrome (ARDS). Author: Candelaria de Haro; Ary Serpa Neto; Gemma Gomà; Maria Elena González; Alfonso Ortega; Catalina Forteza; Fernando Frutos-Vivar; Raquel García; Fabienne D. Simonis; Federico Gordo-Vidal; David Suarez; Marcus J. Schultz; Antonio Artigas Creator: Adobe InDesign 14.0 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Sat Jun 3 09:51:17 2023 CEST ModDate: Sat Jun 3 09:51:31 2023 CEST Custom Metadata: no Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 770355 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VNMFKC+MuseoSans-500 Type 1C Custom yes yes yes 8 0 TKNTIG+MuseoSans-300 Type 1C Custom yes yes yes 9 0 RHJHGK+MuseoSans-700 Type 1C Custom yes yes yes 10 0 PEKVEO+STIXGeneral-Regular Type 1C Custom yes yes yes 12 0 OFAPQQ+MuseoSans-300Italic Type 1C WinAnsi yes yes yes 1283 0 NBLJCS+MinionPro-Regular Type 1C Custom yes yes yes 11 0 KZXRMY+MinionPro-It Type 1C Custom yes yes yes 34 0 IWYFKC+MuseoSans-500Italic Type 1C WinAnsi yes yes yes 51 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-03-28 02:38:53 CET RepresentationInformation: pmc_10282840.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-03-15 02:38:08 CET Size: 770355 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 1335 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-GB Outlines: Item: Title: Effect of a low versus intermediate tidal volume strategy on pulmonary complications in patients at risk of acute respiratory distress syndrome—a randomized clinical trial Children: Item: Title: 1. Introduction Item: Title: 2. Materials and methods Children: Item: Title: 2.1. Study design Item: Title: 2.2. Patients Item: Title: 2.3. Randomization Item: Title: 2.4. Interventions Item: Title: 2.5. Standard ventilatory care Item: Title: 2.6. Outcomes Item: Title: 2.7. Definitions Item: Title: 2.8. Power calculation Item: Title: 2.9. Statistical analysis plan Item: Title: 3. Results Children: Item: Title: 3.1. Patients Item: Title: 3.2. Intervention Item: Title: 3.3. Development of ARDS Item: Title: 3.4. Secondary endpoints Item: Title: 3.5. Sensitivity analysis Item: Title: 4. Discussion Item: Title: 5. Conclusion Item: Title: Data availability statement Item: Title: Ethics statement Item: Title: Author contributions Item: Title: Conflict of interest Item: Title: Publisher’s note Item: Title: References Info: Title: Effect of a low versus intermediate tidal volume strategy on pulmonary complications in patients at risk of acute respiratory distress syndrome a randomized clinical trial Author: Candelaria de Haro; Ary Serpa Neto; Gemma Gomà; Maria Elena González; Alfonso Ortega; Catalina Forteza; Fernando Frutos-Vivar; Raquel García; Fabienne D. Simonis; Federico Gordo-Vidal; David Suarez; Marcus J. Schultz; Antonio Artigas Subject: Introduction: There is no consensus on whether invasive ventilation should use low tidal volumes (VT) to prevent lung complications in patients at risk of acute respiratory distress syndrome (ARDS). 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tidal volume strategy on pulmonary complications in patients at risk of acute respiratory distress syndrome—a randomized clinical trial Candelaria de Haro Ary Serpa Neto Gemma Gomà Maria Elena González Alfonso Ortega Catalina Forteza Fernando Frutos-Vivar Raquel García Fabienne D. Simonis Federico Gordo-Vidal David Suarez Marcus J. Schultz Antonio Artigas Introduction: There is no consensus on whether invasive ventilation should use low tidal volumes (VT) to prevent lung complications in patients at risk of acute respiratory distress syndrome (ARDS). intensive care critical care mechanical ventilation lung protection tidal volume ARDS mortality Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 47, 808, 218, 790 Annotation: Subtype: Link Rect: 49, 41, 117, 33 Annotation: Subtype: Link Rect: 499, 41, 545, 33 Annotation: Subtype: Link Rect: 47, 717, 203, 699 Annotation: Subtype: Link Rect: 215, 720, 545, 696 Annotation: Subtype: Link Rect: 215, 695, 450, 671 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