f730a4aba6fd72ae1993c14564dd6de3 pmc_10299091.pdf 1942efae742a9b7ea89cc7a56b4176ac8941e80b pmc_10299091.pdf 291b69f494077180c66fb59497b3f32aaaac97076b59aee3be34b8bc8b4bfbb4 pmc_10299091.pdf Title: Low Correlation between Gait and Quality of Life in Advanced Knee Osteoarthritis Subject: Advanced knee osteoarthritis patients’ gait usually undergoes alterations leading to decreased mobility and lower functional performance, which can result in a worsening of their quality of life (QoL). While several authors have reported a moderate correlation between gait parameters and QoL assessed by generic questionnaires, the literature is scarce. This study aimed to explore the relationship between gait and QoL parameters assessed by a generic and a disease-specific questionnaire in patients with advanced knee osteoarthritis. In this single-centre, prospective, observational study, 129 patients with advanced knee osteoarthritis scheduled for elective total knee replacement were selected. The patients’ gait was evaluated by means of a validated wireless device while they walked 30 m at a comfortable speed. Patient function was also analysed using the Knee Society Score (KSS). QoL was measured with the EQ-5D and the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaires. Patients showed a mean walking speed of 0.95 0.19 m/s, a mean cadence of 105.6 9.9 steps/min, and a mean stride length of 1.25 0.17 m on both legs. They presented poor knee status (KSS < 60) and poor QoL, with an EQ-5D of 0.44 0.24 and a total KOOS of 29.77 13.99. Positive low correlations (r < 0.5, p < 0.5) were found only between the speed, propulsion and stride length of both legs, and the overall and ADLs subscale scores of the total KOOS questionnaire. In conclusion, several gait parameters have a significant low correlation with the QoL of patients with advanced knee osteoarthritis, as assessed by an osteoarthritis-specific questionnaire. Keywords: advanced knee osteoarthritis; gait; quality of life; activities of daily living; KOOS; EQ-5D Author: Valentín Freijo, Claudia Navarro, Begoña Molina and Jordi Villalba Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Thu Jun 8 10:59:34 2023 CEST ModDate: Thu Jun 8 11:25:32 2023 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 762285 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- APWKLL+VnURWPalladioL Type 1 Custom yes yes no 10 0 LMJGTF+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 XNCKMP+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 JXVBQC+URWPalladioL-Ital Type 1 Custom yes yes no 24 0 KOSUXD+CMSY10 Type 1 Builtin yes yes no 28 0 WLENKM+VnURWPalladioL-Bold Type 1 Custom yes yes no 32 0 ODVVLZ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 50 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 53 0 INCJJD+PalatinoLinotype CID TrueType Identity-H yes yes yes 76 0 INCJJG+PalatinoLinotype,Italic Type 1C WinAnsi yes yes no 81 0 INCJJC+PalatinoLinotype,Bold Type 1C WinAnsi yes yes no 84 0 INCJJE+PalatinoLinotype2 Type 1C WinAnsi yes yes no 87 0 INCKLA+PalatinoLinotype3 Type 1C MacRoman yes yes no 90 0 INCLFN+PalatinoLinotype,Bold2 Type 1C MacRoman yes yes no 93 0 GEJNTL+VnURWPalladioL-Italic Type 1 Custom yes yes no 115 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-09-14 02:29:32 CEST RepresentationInformation: pmc_10299091.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-09-13 02:17:52 CEST Size: 762285 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 280 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@44c8afef Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7b69c6ba Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@46daef40 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@12f41634 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13c27452 Info: Title: Low Correlation between Gait and Quality of Life in Advanced Knee Osteoarthritis Author: Valentín Freijo, Claudia Navarro, Begoña Molina and Jordi Villalba Subject: Advanced knee osteoarthritis patients’ gait usually undergoes alterations leading to decreased mobility and lower functional performance, which can result in a worsening of their quality of life (QoL). While several authors have reported a moderate correlation between gait parameters and QoL assessed by generic questionnaires, the literature is scarce. This study aimed to explore the relationship between gait and QoL parameters assessed by a generic and a disease-specific questionnaire in patients with advanced knee osteoarthritis. In this single-centre, prospective, observational study, 129 patients with advanced knee osteoarthritis scheduled for elective total knee replacement were selected. The patients’ gait was evaluated by means of a validated wireless device while they walked 30 m at a comfortable speed. Patient function was also analysed using the Knee Society Score (KSS). QoL was measured with the EQ-5D and the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaires. Patients showed a mean walking speed of 0.95 0.19 m/s, a mean cadence of 105.6 9.9 steps/min, and a mean stride length of 1.25 0.17 m on both legs. They presented poor knee status (KSS < 60) and poor QoL, with an EQ-5D of 0.44 0.24 and a total KOOS of 29.77 13.99. Positive low correlations (r < 0.5, p < 0.5) were found only between the speed, propulsion and stride length of both legs, and the overall and ADLs subscale scores of the total KOOS questionnaire. In conclusion, several gait parameters have a significant low correlation with the QoL of patients with advanced knee osteoarthritis, as assessed by an osteoarthritis-specific questionnaire. Keywords: advanced knee osteoarthritis; gait; quality of life; activities of daily living; KOOS; EQ-5D Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Thu Jun 08 10:59:34 CEST 2023 ModDate: Thu Jun 08 11:25:32 CEST 2023 ID: 0xa7f8df2b8fbfc2e84939bace435c0ccd, 0xa7f8df2b8fbfc2e84939bace435c0ccd Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: WLENKM+VnURWPalladioL-Bold FontSubset: true FirstChar: 189 LastChar: 189 FontDescriptor: FontName: WLENKM+VnURWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: GEJNTL+VnURWPalladioL-Italic FontSubset: true FirstChar: 178 LastChar: 189 FontDescriptor: FontName: GEJNTL+VnURWPalladioL-Italic Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: XNCKMP+URWPalladioL-Roma FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: XNCKMP+URWPalladioL-Roma Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: JXVBQC+URWPalladioL-Ital FontSubset: true FirstChar: 45 LastChar: 241 FontDescriptor: FontName: JXVBQC+URWPalladioL-Ital Flags: Symbolic FontBBox: -170, -305, 1010, 941 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: APWKLL+VnURWPalladioL FontSubset: true FirstChar: 128 LastChar: 243 FontDescriptor: FontName: APWKLL+VnURWPalladioL Flags: Symbolic FontBBox: -166, -283, 1021, 943 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: KOSUXD+CMSY10 FontSubset: true FirstChar: 0 LastChar: 21 FontDescriptor: FontName: KOSUXD+CMSY10 Flags: Symbolic FontBBox: -29, -960, 1116, 775 FontFile: true Font: BaseFont: LMJGTF+URWPalladioL-Bold FontSubset: true FirstChar: 2 LastChar: 241 FontDescriptor: FontName: LMJGTF+URWPalladioL-Bold Flags: Symbolic FontBBox: -152, -301, 1000, 935 FontFile: true EncodingDictionary: Differences: true Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 98, 292, 152, 301 Annotation: Subtype: Link Rect: 34, 280, 101, 289 Annotation: Subtype: Link Rect: 34, 164, 96, 186 Annotation: Subtype: Link Rect: 126, 90, 154, 99 Annotation: Subtype: Link Rect: 34, 78, 147, 87 Annotation: Subtype: Link Rect: 34, 756, 176, 792 Annotation: Subtype: Link Rect: 515, 756, 560, 792 Annotation: Subtype: Link Rect: 196, 130, 203, 139 ActionDest: 112 Annotation: Subtype: Link Rect: 206, 130, 213, 139 ActionDest: 112 Annotation: Subtype: Link Rect: 167, 17, 304, 28 Annotation: Subtype: Link Rect: 420, 17, 560, 28 Annotation: Subtype: Link Rect: 34, 366, 87, 385 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 438, 685, 445, 694 ActionDest: 112 Annotation: Subtype: Link Rect: 445, 685, 452, 694 ActionDest: 112 Annotation: Subtype: Link Rect: 453, 685, 460, 694 ActionDest: 112 Annotation: Subtype: Link Rect: 463, 685, 475, 694 ActionDest: 119 Annotation: Subtype: Link Rect: 434, 585, 441, 594 ActionDest: 112 Annotation: Subtype: Link Rect: 444, 585, 451, 594 ActionDest: 112 Annotation: Subtype: Link Rect: 452, 585, 464, 594 ActionDest: 119 Annotation: Subtype: Link Rect: 431, 522, 443, 531 ActionDest: 119 Annotation: Subtype: Link Rect: 197, 510, 209, 519 ActionDest: 119 Annotation: Subtype: Link Rect: 482, 497, 494, 506 ActionDest: 119 Annotation: Subtype: Link Rect: 516, 246, 528, 255 ActionDest: 119 Annotation: Subtype: Link Rect: 318, 108, 330, 117 ActionDest: 119 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 527, 657, 534, 669 ActionDest: 70 Annotation: Subtype: Link Rect: 432, 582, 439, 596 ActionDest: 97 Annotation: Subtype: Link Rect: 544, 560, 556, 569 ActionDest: 119 Annotation: Subtype: Link Rect: 443, 169, 455, 178 ActionDest: 119 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 482, 723, 494, 732 ActionDest: 119 Annotation: Subtype: Link Rect: 237, 397, 249, 406 ActionDest: 119 Annotation: Subtype: Link Rect: 276, 297, 288, 306 ActionDest: 119 Annotation: Subtype: Link Rect: 448, 193, 455, 205 ActionDest: 100 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 266, 533, 277, 541 ActionDest: 119 Annotation: Subtype: Link Rect: 211, 456, 218, 468 ActionDest: 100 Annotation: Subtype: Link Rect: 505, 296, 512, 308 ActionDest: 103 Annotation: Subtype: Link Rect: 322, 183, 329, 195 ActionDest: 103 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 306, 163, 318, 172 ActionDest: 119 Annotation: Subtype: Link Rect: 318, 126, 330, 135 ActionDest: 119 Annotation: Subtype: Link Rect: 331, 126, 343, 135 ActionDest: 119 Annotation: Subtype: Link Rect: 423, 113, 435, 122 ActionDest: 119 Annotation: Subtype: Link Rect: 435, 113, 447, 122 ActionDest: 119 Annotation: Subtype: Link Rect: 339, 88, 351, 97 ActionDest: 119 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 229, 735, 241, 744 ActionDest: 119 Annotation: Subtype: Link Rect: 242, 735, 254, 744 ActionDest: 119 Annotation: Subtype: Link Rect: 478, 723, 490, 732 ActionDest: 119 Annotation: Subtype: Link Rect: 490, 723, 502, 732 ActionDest: 119 Annotation: Subtype: Link Rect: 544, 698, 556, 707 ActionDest: 119 Annotation: Subtype: Link Rect: 219, 647, 231, 657 ActionDest: 119 Annotation: Subtype: Link Rect: 231, 647, 243, 657 ActionDest: 119 Annotation: Subtype: Link Rect: 244, 647, 256, 657 ActionDest: 119 Annotation: Subtype: Link Rect: 543, 560, 555, 569 ActionDest: 119 Annotation: Subtype: Link Rect: 229, 509, 241, 519 ActionDest: 122 Annotation: Subtype: Link Rect: 241, 509, 253, 519 ActionDest: 122 Annotation: Subtype: Link Rect: 509, 509, 521, 519 ActionDest: 122 Annotation: Subtype: Link Rect: 522, 509, 534, 519 ActionDest: 122 Annotation: Subtype: Link Rect: 190, 434, 197, 443 ActionDest: 112 Annotation: Subtype: Link Rect: 198, 434, 205, 443 ActionDest: 112 Annotation: Subtype: Link Rect: 205, 434, 217, 443 ActionDest: 122 Annotation: Subtype: Link Rect: 314, 334, 326, 343 ActionDest: 122 Annotation: Subtype: Link Rect: 241, 321, 253, 330 ActionDest: 122 Annotation: Subtype: Link Rect: 543, 309, 555, 318 ActionDest: 122 Annotation: Subtype: Link Rect: 400, 246, 412, 255 ActionDest: 122 Annotation: Subtype: Link Rect: 297, 208, 309, 217 ActionDest: 119 Annotation: Subtype: Link Rect: 322, 146, 334, 154 ActionDest: 119 Annotation: Subtype: Link Rect: 355, 70, 367, 79 ActionDest: 119 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 545, 735, 556, 744 ActionDest: 119 Annotation: Subtype: Link Rect: 355, 510, 362, 519 ActionDest: 112 Annotation: Subtype: Link Rect: 362, 509, 369, 519 ActionDest: 112 Annotation: Subtype: Link Rect: 370, 509, 382, 519 ActionDest: 122 Annotation: Subtype: Link Rect: 382, 509, 394, 519 ActionDest: 122 Annotation: Subtype: Link Rect: 408, 397, 420, 406 ActionDest: 119 Annotation: Subtype: Link Rect: 421, 396, 433, 406 ActionDest: 122 Annotation: Subtype: Link Rect: 480, 296, 487, 305 ActionDest: 112 Annotation: Subtype: Link Rect: 488, 296, 495, 305 ActionDest: 112 Annotation: Subtype: Link Rect: 495, 296, 507, 305 ActionDest: 122 Annotation: Subtype: Link Rect: 508, 296, 520, 305 ActionDest: 122 Annotation: Subtype: Link Rect: 544, 183, 556, 192 ActionDest: 122 Annotation: Subtype: Link Rect: 448, 145, 460, 154 ActionDest: 122 Annotation: Subtype: Link Rect: 419, 133, 431, 142 ActionDest: 122 Annotation: Subtype: Link Rect: 217, 108, 229, 117 ActionDest: 122 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 536, 584, 560, 595 Annotation: Subtype: Link Rect: 165, 571, 375, 583 Annotation: Subtype: Link Rect: 519, 257, 557, 268 Annotation: Subtype: Link Rect: 59, 247, 95, 257 Annotation: Subtype: Link Rect: 423, 223, 461, 234 Annotation: Subtype: Link Rect: 467, 223, 503, 234 Annotation: Subtype: Link Rect: 131, 201, 168, 211 Annotation: Subtype: Link Rect: 174, 201, 210, 211 Annotation: Subtype: Link Rect: 194, 177, 232, 188 Annotation: Subtype: Link Rect: 236, 154, 274, 165 Annotation: Subtype: Link Rect: 281, 131, 318, 142 Annotation: Subtype: Link Rect: 506, 108, 543, 119 Annotation: Subtype: Link Rect: 325, 86, 363, 96 Annotation: Subtype: Link Rect: 430, 62, 467, 73 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 151, 722, 188, 733 Annotation: Subtype: Link Rect: 519, 710, 557, 721 Annotation: Subtype: Link Rect: 59, 699, 95, 710 Annotation: Subtype: Link Rect: 386, 676, 423, 687 Annotation: Subtype: Link Rect: 429, 676, 465, 687 Annotation: Subtype: Link Rect: 298, 652, 336, 664 Annotation: Subtype: Link Rect: 478, 629, 515, 640 Annotation: Subtype: Link Rect: 521, 629, 557, 640 Annotation: Subtype: Link Rect: 460, 596, 498, 606 Annotation: Subtype: Link Rect: 504, 596, 540, 606 Annotation: Subtype: Link Rect: 338, 572, 375, 585 Annotation: Subtype: Link Rect: 230, 550, 267, 560 Annotation: Subtype: Link Rect: 453, 526, 490, 537 Annotation: Subtype: Link Rect: 59, 492, 96, 502 Annotation: Subtype: Link Rect: 469, 468, 506, 479 Annotation: Subtype: Link Rect: 217, 445, 255, 456 Annotation: Subtype: Link Rect: 254, 422, 291, 433 Annotation: Subtype: Link Rect: 442, 399, 480, 410 Annotation: Subtype: Link Rect: 168, 377, 206, 387 Annotation: Subtype: Link Rect: 499, 353, 537, 364 Annotation: Subtype: Link Rect: 258, 319, 295, 330 Annotation: Subtype: Link Rect: 478, 273, 515, 284 Annotation: Subtype: Link Rect: 521, 273, 557, 284 Annotation: Subtype: Link Rect: 341, 250, 379, 261 Annotation: Subtype: Link Rect: 385, 250, 421, 261 Annotation: Subtype: Link Rect: 59, 216, 96, 226 Annotation: Subtype: Link Rect: 102, 216, 138, 226 Annotation: Subtype: Link Rect: 467, 192, 504, 203 Annotation: Subtype: Link Rect: 122, 159, 159, 169 Annotation: Subtype: Link Rect: 479, 135, 515, 146 Annotation: Subtype: Link Rect: 521, 135, 557, 146 Annotation: Subtype: Link Rect: 449, 112, 486, 123 Annotation: Subtype: Link Rect: 492, 112, 528, 123 Annotation: Subtype: Link Rect: 219, 78, 256, 88 Annotation: Subtype: Link Rect: 262, 78, 298, 88 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 336, 722, 373, 733 Annotation: Subtype: Link Rect: 191, 688, 229, 698 Annotation: Subtype: Link Rect: 360, 664, 398, 675 Annotation: Subtype: Link Rect: 437, 629, 475, 640 Annotation: Subtype: Link Rect: 59, 596, 96, 606 Annotation: Subtype: Link Rect: 516, 572, 554, 583 Annotation: Subtype: Link Rect: 451, 549, 489, 560 Annotation: Subtype: Link Rect: 495, 549, 531, 560 Annotation: Subtype: Link Rect: 394, 526, 432, 537 Annotation: Subtype: Link Rect: 438, 526, 474, 537 Annotation: Subtype: Link Rect: 131, 481, 168, 491 Annotation: Subtype: Link Rect: 175, 481, 211, 491 Annotation: Subtype: Link Rect: 453, 457, 490, 468 Annotation: Subtype: Link Rect: 520, 434, 557, 445 Annotation: Subtype: Link Rect: 185, 399, 222, 410 Checksum: e6dfd7fb Type: CRC32 Checksum: f730a4aba6fd72ae1993c14564dd6de3 Type: MD5 Checksum: 1942efae742a9b7ea89cc7a56b4176ac8941e80b Type: SHA-1