TYPE Correction PUBLISHED 13 June 2023 DOI 10.3389/fpsyt.2023.1200313 Corrigendum: Influence of clinical OPEN ACCESS and neurocognitive factors in psychosocial functioning after a EDITED AND REVIEWED BY Wing Chung Chang, The University of Hong Kong, Hong Kong SAR, China *CORRESPONDENCE first episode non-affective Eduard Vieta evieta@clinic.cat Carla Torrent psychosis: differences between † ctorrent@recerca.clinic.cat These authors share first authorship males and females RECEIVED 04 April 2023 ACCEPTED 23 May 2023 Maria Serra-Navarro1,2† , Silvia Amoretti1,2,3,4† , Norma Verdolini1,2,5 , PUBLISHED 13 June 2023 María Florencia Forte1,3 , Ana M. Sánchez-Torres6,7 , CITATION Serra-Navarro M, Amoretti S, Verdolini N, Eduard Vieta1,2*, Derek Clougher1 , Antonio Lobo2,8 , Forte MF, Sánchez-Torres AM, Vieta E, Clougher D, Lobo A, González-Pinto A, Ana González-Pinto2,9,10 , Rocío Panadero2,11 , Alexandra Roldán2,12 , Panadero R, Roldán A, Carvalho AF, de la André F. Carvalho13 , Elena de la Serna2,14 , Alba Toll2,15 , Serna E, Toll A, Ramos-Quiroga JA, Torrent C, Cuesta MJ, Bernardo M and PEPs Group (2023) J. A. Ramos-Quiroga2,4,16,17 , Carla Torrent1,2*, Manuel J. Cuesta6,7 , Corrigendum: Influence of clinical and neurocognitive factors in psychosocial Miguel Bernardo2,3 and PEPs Group functioning after a first episode non-affective 1 Bipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, psychosis: differences between males and University of Barcelona, Barcelona, Catalonia, Spain, 2 Biomedical Research Networking Center for females. Front. Psychiatry 14:1200313. Mental Health Network (CIBERSAM), Barcelona, Spain, 3 Barcelona Clinic Schizophrenia Unit, Hospital doi: 10.3389/fpsyt.2023.1200313 Clinic of Barcelona, Neuroscience Institute, August Pi I Sunyer Biomedical Research Institute (IDIBAPS), COPYRIGHT University of Barcelona, Barcelona, Spain, 4 Psychiatric Genetics Unit, Group of Psychiatry, Mental Health © 2023 Serra-Navarro, Amoretti, Verdolini, and Addictions, Vall d’Hebron Research Institute (VHIR), Barcelona, Catalonia, Spain, 5 Local Health Unit Forte, Sánchez-Torres, Vieta, Clougher, Lobo, Umbria 1, Department of Mental Health, Mental Health Center of Perugia, Perugia, Italy, 6 Department of González-Pinto, Panadero, Roldán, Carvalho, Psychiatry, Complejo Hospitalario de Navarra, Pamplona, Spain, 7 IdiSNA, Navarra Institute for Health de la Serna, Toll, Ramos-Quiroga, Torrent, Research, Pamplona, Spain, 8 Department of Medicine and Psychiatry, Instituto de Investigación Sanitaria Cuesta, Bernardo and PEPs Group. This is an Aragón (IIS Aragón), Zaragoza University, Zaragoza, Spain, 9 Araba University Hospital, Bioaraba Research open-access article distributed under the terms Institute, Vitoria-Gasteiz, Spain, 10 Department of Psychiatry, University of the Basque Country of the Creative Commons Attribution License (UPV-EHU), Vitoria-Gasteiz, Spain, 11 Department of Child and Adolescent Psychiatry, Hospital General (CC BY). The use, distribution or reproduction Universitario Gregorio Marañón, School of Medicine, Institute of Psychiatry and Mental Health, in other forums is permitted, provided the Universidad Complutense, IiSGM, Madrid, Spain, 12 Department of Psychiatry, Hospital de la Santa Creu i original author(s) and the copyright owner(s) Sant Pau, Institut d’Investigació Biomèdica-Sant Pau (IIB-SANT PAU), Universitat Autònoma de Barcelona are credited and that the original publication in (UAB), Barcelona, Spain, 13 Innovation in Mental and Physical Health and Clinical Treatment (IMPACT), this journal is cited, in accordance with School of Medicine, Barwon Health, The Institute for Mental and Physical Health and Clinical Translation, accepted academic practice. No use, Deakin University, Geelong, VIC, Australia, 14 Department of Child and Adolescent Psychiatry and distribution or reproduction is permitted which Psychology, 2017SGR881, Institut Clínic de Neurociències, Hospital Clínic Universitari, CIBERSAM, does not comply with these terms. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Medicine, University of Barcelona, Barcelona, Spain, 15 Hospital del Mar Medical Research Institute (IMIM), Universitat Autònoma de Barcelona (UAB), Barcelona, Spain, 16 Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Catalonia, Spain, 17 Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain KEYWORDS first episode non-affective psychosis, psychosocial functioning, sex differences, cognition, negative symptoms A corrigendum on Influence of clinical and neurocognitive factors in psychosocial functioning after a first episode non-affective psychosis: differences between males and females by Serra-Navarro, M., Amoretti, S., Verdolini, N., Forte, M. F., Sánchez-Torres, A. M., Vieta, E., Clougher, D., Lobo, A., González-Pinto, A., Panadero, R., Roldán, A., Carvalho, A. F., de la Serna, E., Toll, A., Ramos-Quiroga, J. A., Torrent, C., Cuesta, M. J., Bernardo, M., and PEPs Group. (2022). Front. Psychiatry 13:982583. doi: 10.3389/fpsyt.2022.982583 Frontiers in Psychiatry 01 frontiersin.org Serra-Navarro et al. 10.3389/fpsyt.2023.1200313 In the published article, there was an error. The title of a The corrected sentence appears below: sub-section is incorrect. “Two main findings emerged from the present study. Firstly, A correction has been made to Results, Changes in cognitive individuals with FEP had higher substance abuse, lower SES, functions and psychosocial functioning, paragraph 4. This title worse psychosocial functioning and neurocognitive performance previously stated: in all cognitive domains in relation to the HC group (27, 61). “Changes in cognitive functions and psychosocial functioning” As expected, individuals with FEP present more difficulties and The corrected sentence appears below: impairments than the HC group. Secondly, different effects of sex “Changes in cognitive and clinical characteristics and were found regardless of the group. The male group uses more psychosocial functioning” tobacco and cannabis, are younger, have higher CR and CPZ doses, In the published article, there was an error. Part of a paragraph worse premorbid adjustment and perform better in attention and was incorrectly included. processing speed. These differences have been found in individuals A correction has been made to Discussion, paragraph 1. This with schizophrenia. Males tend to show a higher incidence of the sentence previously stated: disorder, an earlier age at onset, poorer premorbid adjustment, “Two main findings emerged from the present study. Firstly, higher rates of substance abuse, worse psychosocial functioning, individuals with FEP had higher substance abuse, lower SES, and a more severe course of the disease, especially in negative worse psychosocial functioning and neurocognitive performance symptoms, while in the FEP group mixed results have been found in all cognitive domains in relation to the HC group (27, 61). (14, 62, 63). In addition, males with psychosis require higher As expected, individuals with FEP present more difficulties and doses of antipsychotic than females (21). In terms of premorbid impairments than the HC group. Secondly, different effects of adjustment, no significant differences were found in our study, sex were found regardless of the group. The male group uses failing to replicate the results of Cotton et al. (64). Previous more tobacco and cannabis, are younger, have higher CR and literature suggests that males have greater negative symptoms CPZ doses, worse premorbid adjustment and perform better in than females with FEP, especially related to emotional withdrawal, attention and processing speed. These differences have been found blunted affects, and avolition-apathy (13, 25, 65, 66). However, in in individuals with schizophrenia. Males tend to show a higher our study, no significant differences were found in this regard. incidence of the disorder, an earlier age at onset, poorer premorbid These results might be interpreted in the light of different models adjustment, higher rates of substance abuse, worse psychosocial that explain SZ spectrum disorders. The neurodevelopmental functioning, and a more severe course of the disease, especially in model of SZ posits that the illness is the end stage of abnormal negative symptoms, while in the FEP group mixed results have been neurodevelopmental processes that began years before the onset found (14, 62). In addition, males with psychosis require higher of the illness (64). Within this theoretical framework, an attempt doses of antipsychotic than females (21). In terms of premorbid to describe relationships between sex/gender and indicators of adjustment, no significant differences were found in our study, neurodevelopment compromise in SZ has been made, but no failing to replicate the results of Cotton et al. (64). Previous associations regarding sex were found (62).” literature suggests that males have greater negative symptoms In the published article, the citation 66, Choi et al., 2009 was than females with FEP, especially related to emotional withdrawal, incorrectly placed and numbered. blunted affects, and avolition-apathy (13, 25, 65, 66). However, in The reference should be cited in the sentence: “mixed results our study, no significant differences were found in this regard. have been found (Ochoa et al., 2012; Navarra-Ventura et al., 2021; These results might be interpreted in the light of different models Choi et al., 2009) (14, 62, 63). In addition, males with psychosis that explain SZ spectrum disorders. The neurodevelopmental require higher doses”, and be numbered as reference 63: model of SZ posits that the illness is the end stage of abnormal 63. Choi JS, Chon MW, Kang DH, Jung MH, Kwon neurodevelopmental processes that began years before the onset JS. Gender difference in the prodromal symptoms of first- of the illness (64). Within this theoretical framework, an attempt episode Schizophrenia. J Korean Med Sci. (2009) 24:1083–8. to describe relationships between sex/gender and indicators of doi: 10.3346/jkms.2009.24.6.1083 neurodevelopment compromise in SZ has been made, but no As consequence, references 63 (Cotton SM et al. 2009), 64 associations regarding sex were found (62). In SZ, sex differences (González-Rodríguez A, 2014) and 65 (Hui CLM, 2016) were have been found, were men tend to show a higher incidence of renumbered as: the disorder, an earlier age at onset, poorer premorbid adjustment, 64. Cotton SM, Lambert M, Schimmelmann BG, Foley DL, higher rates of substance abuse, worse psychosocial functioning, Morley KI, McGorry PD, et al. Gender differences in premorbid, and a more severe course of the disease, especially in negative entry, treatment, and outcome characteristics in a treated symptoms (14, 62, 66) while in the FEP group mixed results epidemiological sample of 661 patients with first episode psychosis. have been found. In fact, in the present study no differences Schizophr Res. (2009) 114:17–24. doi: 10.1016/j.schres.2009. were found in regards to clinical or functional aspects. This could 07.002 be interpreted in light of the neurodegenerative hypothesis (64), 65. González-Rodríguez A, Studerus E, Spitz A, Bugra H, Aston suggesting that SZ is a disorder that debuts at an early age, and J, Borgwardt S, et al. Gender Differences in the Psychopathology from that moment on, a neurodegenerative process begins and the of Emerging Psychosis. Isr J Psychiatry Relat Sci. (2014) subject progressively loses capacities.” 51:85–92. Frontiers in Psychiatry 02 frontiersin.org Serra-Navarro et al. 10.3389/fpsyt.2023.1200313 66. Hui CLM, Leung CM, Chang WC, Chan SKW, Lee Publisher’s note EHM, Chen EYH. Examining gender difference in adult-onset psychosis in Hong Kong. Early Interv Psychiatry. (2016) 10:324–33. All claims expressed in this article are solely those of the doi: 10.1111/eip.12167 authors and do not necessarily represent those of their affiliated The authors apologize for this error and state organizations, or those of the publisher, the editors and the that this does not change the scientific conclusions reviewers. Any product that may be evaluated in this article, or of the article in any way. The original article has claim that may be made by its manufacturer, is not guaranteed or been updated. endorsed by the publisher. References 63. Choi JS, Chon MW, Kang DH, Jung MH, Kwon JS. Gender difference in 65. González-Rodríguez A, Studerus E, Spitz A, Bugra H, Aston J, Borgwardt S, et the prodromal symptoms of first-episode Schizophrenia. J Korean Med Sci. (2009) al. Gender Differences in the Psychopathology of Emerging Psychosis. Isr J Psychiatry 24:1083–8. doi: 10.3346/jkms.2009.24.6.1083 Relat Sci. (2014) 51:85–92. 64. Cotton SM, Lambert M, Schimmelmann BG, Foley DL, Morley KI, McGorry PD, 66. Hui CLM, Leung CM, Chang WC, Chan SKW, Lee EHM, et al. Gender differences in premorbid, entry, treatment, and outcome characteristics in Chen EYH. Examining gender difference in adult-onset psychosis in a treated epidemiological sample of 661 patients with first episode psychosis. Schizophr Hong Kong. Early Interv Psychiatry. (2016) 10:324–33. doi: 10.1111/eip. Res. (2009) 114:17–24. doi: 10.1016/j.schres.2009.07.002 12167 Frontiers in Psychiatry 03 frontiersin.org