12c71aa832743184feb9c7cab8afa542 pmc_10327497.pdf 2350613e5979a9f61e194410db0a9f7ffcb4df2f pmc_10327497.pdf 4c46a287bee25e102f488ff9fc03947c154ec12ee0b2b5cb64615d7179c22ec6 pmc_10327497.pdf Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Fri Jun 2 14:29:48 2023 CEST ModDate: Fri Jun 2 14:29:52 2023 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 2243237 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NJZDYO+DINNextLTPro-Light Type 1C Custom yes yes yes 331 0 KHLLIU+DINNextLTPro-Regular Type 1C Custom yes yes yes 332 0 GBINEC+DINNextLTPro-Italic Type 1C Custom yes yes yes 333 0 CWQWKK+DINNextLTPro-Bold Type 1C Custom yes yes yes 348 0 EYJBCG+DINNextLTPro-LightItalic Type 1C Custom yes yes yes 349 0 CVKPAK+DINNextLTPro-Medium Type 1C WinAnsi yes yes yes 357 0 CWQWKK+DINNextLTPro-Bold Type 1C WinAnsi yes yes no 376 0 CWQWKK+DINNextLTPro-Bold Type 1C WinAnsi yes yes no 384 0 BRVJMM+MinionPro-Regular Type 1C Custom yes yes yes 241 0 BAMPMM+MinionPro-It Type 1C WinAnsi yes yes yes 245 0 KHLLIU+DINNextLTPro-Regular Type 1C WinAnsi yes yes yes 247 0 GBINEC+DINNextLTPro-Italic Type 1C Custom yes yes yes 255 0 EYJBCG+DINNextLTPro-LightItalic Type 1C WinAnsi yes yes yes 250 0 NJZDYO+DINNextLTPro-Light Type 1C WinAnsi yes yes yes 252 0 VHLAGY+DINNextLTPro-BoldItalic Type 1C WinAnsi yes yes yes 256 0 KHLLIU+DINNextLTPro-Regular Type 1C WinAnsi yes yes yes 258 0 GBINEC+DINNextLTPro-Italic Type 1C Custom yes yes yes 262 0 EYJBCG+DINNextLTPro-LightItalic Type 1C WinAnsi yes yes yes 263 0 NJZDYO+DINNextLTPro-Light Type 1C WinAnsi yes yes yes 261 0 UIWUSA+MinionPro-Bold Type 1C Custom yes yes yes 273 0 ZYGOKQ+MinionPro-BoldIt Type 1C WinAnsi yes yes yes 276 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-05-15 03:24:20 CEST RepresentationInformation: pmc_10327497.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-05-14 02:33:25 CEST Size: 2243237 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 391 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-US Outlines: Item: Title: Comparative genomics uncovered differences between clinical and environmental populations of Vibrio parahaemolyticus in New Zealand Children: Item: Title: Abstract Item: Title: Data Summary Item: Title: Introduction Item: Title: Methods Children: Item: Title: Collection of V. parahaemolyticus isolates Item: Title: DNA extraction and whole-genome sequencing Item: Title: Genome assembly and gene identification Item: Title: Population structure and ancestral source analyses Item: Title: SNP calling and genome phylogeny Item: Title: Presence–absence analysis of virulence encoding genes Item: Title: Analyses of premature stop codons and non-synonymous mutations Item: Title: Results Children: Item: Title: Population structure and ancestral profiles of the environmental and clinical isolates of V. parahaemolyticus Item: Title: Genetic relatedness of the environmental and clinical isolates Item: Title: Presence–absence variations of the virulence-encoding genes Item: Title: Polymorphism in virulence-associated proteins Item: Title: Discussion Item: Title: References Info: Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Fri Jun 02 14:59:48 CEST 2023 ModDate: Fri Jun 02 14:59:52 CEST 2023 ID: 0xa4e1bc53096e65478463a7eb5742ec60, 0x34d61993faa2424e9f39a21d382e8944 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1417 ImageHeight: 1498 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 945 ImageHeight: 1943 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1401 ImageHeight: 1317 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1765 ImageHeight: 1680 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1936 ImageHeight: 1357 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: VHLAGY+DINNextLTPro-BoldItalic FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: VHLAGY+DINNextLTPro-BoldItalic Flags: Nonsymbolic FontBBox: -163, -234, 1048, 924 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: BRVJMM+MinionPro-Regular FontSubset: true FirstChar: 13 LastChar: 225 FontDescriptor: FontName: BRVJMM+MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: UIWUSA+MinionPro-Bold FontSubset: true FirstChar: 31 LastChar: 146 FontDescriptor: FontName: UIWUSA+MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: ZYGOKQ+MinionPro-BoldIt FontSubset: true FirstChar: 80 LastChar: 110 FontDescriptor: FontName: ZYGOKQ+MinionPro-BoldIt Flags: Serif, Nonsymbolic, Italic FontBBox: -230, -360, 1684, 1032 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: CVKPAK+DINNextLTPro-Medium FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: CVKPAK+DINNextLTPro-Medium Flags: Nonsymbolic FontBBox: -164, -228, 1027, 920 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: BAMPMM+MinionPro-It FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: BAMPMM+MinionPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: NJZDYO+DINNextLTPro-Light FontSubset: true FirstChar: 28 LastChar: 169 FontDescriptor: FontName: NJZDYO+DINNextLTPro-Light Flags: Nonsymbolic FontBBox: -148, -213, 985, 914 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: CWQWKK+DINNextLTPro-Bold FontSubset: true FirstChar: 31 LastChar: 150 FontDescriptor: FontName: CWQWKK+DINNextLTPro-Bold Flags: Nonsymbolic FontBBox: -170, -238, 1076, 925 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: KHLLIU+DINNextLTPro-Regular FontSubset: true FirstChar: 28 LastChar: 252 FontDescriptor: FontName: KHLLIU+DINNextLTPro-Regular Flags: Nonsymbolic FontBBox: -156, -213, 1008, 917 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: EYJBCG+DINNextLTPro-LightItalic FontSubset: true FirstChar: 31 LastChar: 121 FontDescriptor: FontName: EYJBCG+DINNextLTPro-LightItalic Flags: Nonsymbolic FontBBox: -155, -213, 947, 913 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: GBINEC+DINNextLTPro-Italic FontSubset: true FirstChar: 31 LastChar: 121 FontDescriptor: FontName: GBINEC+DINNextLTPro-Italic Flags: Nonsymbolic FontBBox: -155, -212, 972, 916 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: 2023-06-02T17:59:48+05:30 2023-06-02T17:59:52+05:30 2023-06-02T17:59:52+05:30 Adobe InDesign 15.1 (Windows) uuid:14a52247-a2ed-4913-8e5a-b0637e9cf643 xmp.did:F5ECED53252168118083E0C8553B9672 xmp.id:de345d6f-2f7b-564b-947a-8828abba14f8 proof:pdf xmp.iid:456daa29-254e-0e49-8410-62af165a8e8a xmp.did:6ea8a96c-6d14-8848-9b5f-2225a0683084 xmp.did:F5ECED53252168118083E0C8553B9672 default converted from application/x-indesign to application/pdf Adobe InDesign 15.1 (Windows) / 2023-06-02T17:59:48+05:30 bb25f5fd-e274-4ea1-90b8-d0f8c65361d2 application/pdf Adobe PDF Library 15.0 False Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 42, 750, 166, 721 Annotation: Subtype: Link Rect: 43, 41, 78, 26 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 70, 451, 75, 438 ActionDest: 218 Annotation: Subtype: Link Rect: 522, 428, 527, 415 ActionDest: 218 Annotation: Subtype: Link Rect: 48, 394, 53, 380 ActionDest: 218 Annotation: Subtype: Link Rect: 184, 382, 210, 369 ActionDest: 218 Annotation: Subtype: Link Rect: 411, 371, 416, 357 ActionDest: 227 Annotation: Subtype: Link Rect: 462, 296, 482, 282 ActionDest: 227 Annotation: Subtype: Link Rect: 519, 244, 544, 231 ActionDest: 227 Annotation: Subtype: Link Rect: 235, 181, 245, 168 ActionDest: 227 Annotation: Subtype: Link Rect: 107, 158, 116, 145 ActionDest: 227 Annotation: Subtype: Link Rect: 336, 147, 345, 133 ActionDest: 227 Annotation: Subtype: Link Rect: 178, 135, 187, 122 ActionDest: 227 Annotation: Subtype: Link Rect: 234, 124, 258, 110 ActionDest: 227 Annotation: Subtype: Link Rect: 503, 95, 512, 81 ActionDest: 227 Annotation: Subtype: Link Rect: 48, 60, 58, 47 ActionDest: 227 Annotation: Subtype: Link Rect: 249, 60, 259, 47 ActionDest: 227 Annotation: Subtype: Link Rect: 453, 60, 463, 47 ActionDest: 227 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 77, 705, 87, 691 ActionDest: 227 Annotation: Subtype: Link Rect: 307, 693, 316, 680 ActionDest: 227 Annotation: Subtype: Link Rect: 134, 454, 144, 440 ActionDest: 227 Annotation: Subtype: Link Rect: 157, 419, 167, 406 ActionDest: 227 Annotation: Subtype: Link Rect: 299, 419, 309, 406 ActionDest: 227 Annotation: Subtype: Link Rect: 318, 396, 328, 383 ActionDest: 227 Annotation: Subtype: Link Rect: 261, 265, 271, 252 ActionDest: 227 Annotation: Subtype: Link Rect: 106, 61, 115, 47 ActionDest: 227 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 351, 705, 360, 691 ActionDest: 227 Annotation: Subtype: Link Rect: 477, 682, 487, 668 ActionDest: 227 Annotation: Subtype: Link Rect: 48, 670, 58, 657 ActionDest: 227 Annotation: Subtype: Link Rect: 318, 610, 327, 596 ActionDest: 227 Annotation: Subtype: Link Rect: 48, 575, 223, 562 Annotation: Subtype: Link Rect: 524, 575, 549, 562 Annotation: Subtype: Link Rect: 45, 564, 281, 550 Annotation: Subtype: Link Rect: 517, 564, 527, 550 ActionDest: 227 Annotation: Subtype: Link Rect: 336, 541, 346, 527 ActionDest: 227 Annotation: Subtype: Link Rect: 48, 529, 58, 516 ActionDest: 227 Annotation: Subtype: Link Rect: 199, 460, 208, 447 ActionDest: 227 Annotation: Subtype: Link Rect: 317, 449, 327, 435 ActionDest: 227 Annotation: Subtype: Link Rect: 214, 437, 223, 424 ActionDest: 227 Annotation: Subtype: Link Rect: 278, 426, 288, 412 ActionDest: 227 Annotation: Subtype: Link Rect: 495, 388, 523, 375 ActionDest: 55 Annotation: Subtype: Link Rect: 148, 342, 158, 329 ActionDest: 227 Annotation: Subtype: Link Rect: 515, 251, 521, 243 ActionDest: 227 Annotation: Subtype: Link Rect: 515, 236, 521, 227 ActionDest: 227 Annotation: Subtype: Link Rect: 515, 141, 521, 133 ActionDest: 236 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 515, 260, 544, 247 ActionDest: 55 Annotation: Subtype: Link Rect: 408, 223, 417, 209 ActionDest: 227 Annotation: Subtype: Link Rect: 124, 200, 133, 186 ActionDest: 227 Annotation: Subtype: Link Rect: 234, 188, 244, 175 ActionDest: 227 Annotation: Subtype: Link Rect: 338, 118, 361, 104 ActionDest: 96 Annotation: Subtype: Link Rect: 292, 72, 314, 58 ActionDest: 96 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 445, 670, 468, 657 ActionDest: 96 Annotation: Subtype: Link Rect: 330, 532, 352, 519 ActionDest: 142 Annotation: Subtype: Link Rect: 515, 353, 544, 340 ActionDest: 154 Annotation: Subtype: Link Rect: 380, 319, 402, 305 ActionDest: 184 Annotation: Subtype: Link Rect: 487, 279, 516, 265 ActionDest: 154 Annotation: Subtype: Link Rect: 506, 227, 534, 214 ActionDest: 154 Annotation: Subtype: Link Rect: 446, 193, 474, 179 ActionDest: 154 Annotation: Subtype: Link Rect: 117, 170, 139, 156 ActionDest: 184 Annotation: Subtype: Link Rect: 114, 147, 136, 133 ActionDest: 184 Annotation: Subtype: Link Rect: 297, 118, 325, 104 ActionDest: 154 Annotation: Subtype: Link Rect: 179, 95, 208, 81 ActionDest: 154 Annotation: Subtype: Link Rect: 224, 72, 246, 58 ActionDest: 184 Annotation: Subtype: Link Rect: 163, 61, 191, 47 ActionDest: 154 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 56, 106, 84, 93 ActionDest: 184 Annotation: Subtype: Link Rect: 393, 72, 419, 58 ActionDest: 188 Annotation: Subtype: Link Rect: 464, 60, 499, 47 ActionDest: 188 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 178, 392, 205, 379 ActionDest: 188 Annotation: Subtype: Link Rect: 80, 369, 107, 356 ActionDest: 188 Annotation: Subtype: Link Rect: 225, 306, 262, 293 ActionDest: 199 Annotation: Subtype: Link Rect: 347, 295, 384, 281 ActionDest: 199 Annotation: Subtype: Link Rect: 257, 272, 283, 258 ActionDest: 199 Annotation: Subtype: Link Rect: 477, 237, 504, 224 ActionDest: 199 Annotation: Subtype: Link Rect: 517, 226, 544, 212 ActionDest: 199 Annotation: Subtype: Link Rect: 356, 208, 391, 195 ActionDest: 199 Annotation: Subtype: Link Rect: 495, 185, 521, 172 ActionDest: 199 Annotation: Subtype: Link Rect: 427, 174, 453, 160 ActionDest: 199 Annotation: Subtype: Link Rect: 65, 139, 92, 126 ActionDest: 199 Annotation: Subtype: Link Rect: 293, 116, 319, 103 ActionDest: 199 Page: Sequence: 9 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 203, 160, 356, 147 Annotation: Subtype: Link Rect: 365, 160, 403, 147 ActionDest: 227 Annotation: Subtype: Link Rect: 313, 119, 338, 106 ActionDest: 236 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 319, 296, 329, 282 ActionDest: 236 Annotation: Subtype: Link Rect: 91, 273, 100, 259 ActionDest: 236 Annotation: Subtype: Link Rect: 482, 233, 492, 219 ActionDest: 236 Annotation: Subtype: Link Rect: 185, 221, 194, 208 ActionDest: 236 Annotation: Subtype: Link Rect: 111, 210, 120, 196 ActionDest: 236 Annotation: Subtype: Link Rect: 507, 112, 516, 99 ActionDest: 236 Annotation: Subtype: Link Rect: 521, 60, 546, 47 ActionDest: 236 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 190, 716, 215, 703 ActionDest: 236 Annotation: Subtype: Link Rect: 265, 481, 275, 467 ActionDest: 236 Annotation: Subtype: Link Rect: 481, 481, 491, 467 ActionDest: 227 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 387, 667, 549, 658 Annotation: Subtype: Link Rect: 326, 658, 549, 649 Annotation: Subtype: Link Rect: 326, 649, 492, 640 Page: Sequence: 14 Checksum: 087c092c Type: CRC32 Checksum: 12c71aa832743184feb9c7cab8afa542 Type: MD5 Checksum: 2350613e5979a9f61e194410db0a9f7ffcb4df2f Type: SHA-1 Checksum: 4c46a287bee25e102f488ff9fc03947c154ec12ee0b2b5cb64615d7179c22ec6 Type: SHA-256