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Destination: atl_HBM_26405_ Children: Item: Title: 1 INTRODUCTION Destination: HeadingHBM_26405hbm26405-sec-0001 Item: Title: 2 METHODS Destination: HeadingHBM_26405hbm26405-sec-0002 Children: Item: Title: 2.1 Sample Destination: HeadingHBM_26405hbm26405-sec-0003 Item: Title: 2.2 MRI data acquisition and preprocessing Destination: HeadingHBM_26405hbm26405-sec-0004 Item: Title: 2.3 Models and descriptors Destination: HeadingHBM_26405hbm26405-sec-0005 Item: Title: 2.4 Multimodal spatial normalisation Destination: HeadingHBM_26405hbm26405-sec-0006 Item: Title: 2.5 Statistical analyses Destination: HeadingHBM_26405hbm26405-sec-0007 Item: Title: 2.6 Machine learning algorithms Destination: HeadingHBM_26405hbm26405-sec-0008 Item: Title: 3 RESULTS Destination: HeadingHBM_26405hbm26405-sec-0009 Children: Item: Title: 3.1 Demographic and clinical information Destination: HeadingHBM_26405hbm26405-sec-0010 Item: Title: 3.2 Inter-group comparison Destination: HeadingHBM_26405hbm26405-sec-0011 Item: Title: 3.3 Machine learning: Diagnosis of BD Destination: HeadingHBM_26405hbm26405-sec-0012 Item: Title: 3.4 Associations with pharmacologic treatment Destination: HeadingHBM_26405hbm26405-sec-0013 Item: Title: 3.5 Associations with clinical features Destination: HeadingHBM_26405hbm26405-sec-0014 Item: Title: 4 DISCUSSION Destination: HeadingHBM_26405hbm26405-sec-0015 Children: Item: Title: 4.1 How can we explain the observed changes in terms of biological parameters? Destination: HeadingHBM_26405hbm26405-sec-0016 Item: Title: 4.2 Is FA the most sensitive diffusion metric in BD? Destination: HeadingHBM_26405hbm26405-sec-0017 Item: Title: 4.3 Association between pharmacologic treatment and brain tissue microstructure Destination: HeadingHBM_26405hbm26405-sec-0018 Item: Title: 4.4 Association between clinical features and brain tissue microstructure Destination: HeadingHBM_26405hbm26405-sec-0019 Item: Title: 4.5 Conclusions and limitations Destination: HeadingHBM_26405hbm26405-sec-0020 Item: Title: AUTHOR CONTRIBUTIONS Destination: HeadingHBM_26405hbm26405-sec-0021 Item: Title: ACKNOWLEDGMENTS Destination: HeadingHBM_26405hbm26405-sec-0022 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: HeadingHBM_26405hbm26405-sec-0023 Children: Item: Title: DATA AVAILABILITY STATEMENT Destination: HeadingHBM_26405hbm26405-sec-0025 Item: Title: REFERENCES Destination: HeadingHBM_26405hbm26405-bibl-00011 Info: Title: Widespread intra‐axonal signal fraction abnormalities in bipolar disorder from multi‐compartment diffusion MRI: sensitivity to diagnosis, association with 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