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Subject: Diabetologia, https://doi.org/10.1007/s00125-023-05940-5 Keywords: Diabetic retinopathy;Modifiable risk factors;Neurovascular unit Author: Rafael Simó Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Tue Jul 25 05:50:38 2023 CEST ModDate: Tue Jul 25 05:56:56 2023 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 785438 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-SemiCn Type 1C WinAnsi yes no yes 409 0 MyriadPro-Semibold Type 1C Custom yes no yes 410 0 MyriadPro-SemiboldSemiCn Type 1C Custom yes no yes 418 0 MyriadPro-Bold Type 1C Custom yes no yes 423 0 GWSFNG+STIX-Regular Type 1C Custom yes yes yes 424 0 XFELQH+Wingdings-Regular Type 1C WinAnsi yes yes yes 433 0 SBEQTS+MyriadPro-SemiCn2 Type 1C WinAnsi yes yes yes 456 0 Springnew-Regular Type 1C WinAnsi yes no yes 462 0 MyriadPro-BoldSemiCn Type 1C Custom yes no yes 246 0 Springnew-Regular2 Type 1C WinAnsi yes no yes 260 0 BIKIFV+STIX-Italic Type 1C WinAnsi yes yes yes 270 0 Springnew-Regular3 Type 1C WinAnsi yes no yes 272 0 BWZCVQ+ArialMT Type 1C WinAnsi yes yes no 291 0 BWZCVQ+Arial-BoldMT Type 1C WinAnsi yes yes no 288 0 MyriadPro-Bold2 Type 1C WinAnsi yes no no 287 0 MyriadPro-Regular Type 1C WinAnsi yes no no 290 0 ArialMT2 Type 1C WinAnsi yes no no 302 0 BWZCVQ+Arial-BoldMT2 Type 1C WinAnsi yes yes no 301 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-10-05 02:29:16 CEST RepresentationInformation: pmc_10390367.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-09-29 02:18:58 CEST Size: 785438 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 498 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: What else can we do to prevent diabetic retinopathy? Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Revisiting modifiable risk factors Children: Item: Title: Glycaemic control Item: Title: Blood pressure Item: Title: Dyslipidaemia Item: Title: Obesity Item: Title: Lifestyle Item: Title: Impact of glucose-lowering drugs on diabetic retinopathy Item: Title: New insights and perspectives on diabetic retinopathy prevention based on targeting the NVU Children: Item: Title: Experimental evidence Item: Title: Clinical perspectives Item: Title: References Info: Title: What else can we do to prevent diabetic retinopathy? Author: Rafael Simó Subject: Diabetologia, https://doi.org/10.1007/s00125-023-05940-5 Keywords: Diabetic retinopathy;Modifiable risk factors;Neurovascular unit Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Tue Jul 25 05:50:38 CEST 2023 ModDate: Tue Jul 25 05:56:56 CEST 2023 ID: 0xd58b9172cc6944408306cfd08dcabdd9, 0xabad1c256ec81946963315f7cffe05ce Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2011 ImageHeight: 1496 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: BWZCVQ+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: BWZCVQ+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-SemiboldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldSemiCn Flags: Nonsymbolic FontBBox: -131, -250, 1115, 886 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BWZCVQ+ArialMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: BWZCVQ+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: GWSFNG+STIX-Regular FontSubset: true FirstChar: 23 LastChar: 248 FontDescriptor: FontName: GWSFNG+STIX-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BWZCVQ+Arial-BoldMT2 FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: BWZCVQ+Arial-BoldMT2 Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: BIKIFV+STIX-Italic FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: BIKIFV+STIX-Italic Flags: Serif, Nonsymbolic, Italic FontBBox: -970, -305, 1429, 1023 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: ArialMT2 FirstChar: 32 LastChar: 121 FontDescriptor: FontName: ArialMT2 Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: XFELQH+Wingdings-Regular FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: XFELQH+Wingdings-Regular Flags: Nonsymbolic FontBBox: 0, -103, 1359, 439 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-BoldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-BoldSemiCn Flags: Nonsymbolic FontBBox: -133, -250, 1161, 894 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-SemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiCn Flags: Nonsymbolic FontBBox: -128, -250, 1059, 876 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Bold2 FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold2 Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true Encoding: WinAnsiEncoding XMP: 2023-07-25T03:50:38 Adobe InDesign 15.1 (Windows) 2023-07-25T03:56:56Z 2023-07-25T03:56:56Z Adobe PDF Library 15.0 Diabetic retinopathy;Modifiable risk factors;Neurovascular unit False application/pdf https://doi.org/10.1007/s00125-023-05940-5 Springer Berlin Heidelberg Diabetologia, https://doi.org/10.1007/s00125-023-05940-5 Diabetic retinopathy Modifiable risk factors Neurovascular unit What else can we do to prevent diabetic retinopathy? Rafael Simó Cristina Hernández 10.1007/s00125-023-05940-5 2010-04-23 true springer.com springerlink.com https://doi.org/10.1007/s00125-023-05940-5 10.1007/s00125-023-05940-5 1432-0428 66 9 1614 1621 journal Diabetologia The Author(s) 2010-04-23 true 10.1007/s00125-023-05940-5 noindex springer.com springerlink.com uuid:e6e49c33-8b2d-49ac-84bb-579fd7a4200c uuid:f99ce008-f674-4f67-b606-ec06491a2fa9 default 1 converted uuid:5476ec3e-ad66-406e-a96f-f9793e642330 converted to PDF/A-2b pdfToolbox 2023-07-25T03:56:39Z 2 B Rafael Simó http://orcid.org/0000-0003-0475-3096 Cristina Hernández http://orcid.org/0000-0002-3109-1721 http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. 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