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Id-Lahoucine Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Sat Aug 5 03:07:46 2023 CEST ModDate: Tue Nov 21 14:08:34 2023 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1028931 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- QRKQGQ+Wingdings-Regular Type 1C WinAnsi yes yes yes 592 0 MinionPro-Regular Type 1C Custom yes no yes 52 0 ONKSAQ+Corbel-Bold CID TrueType Identity-H yes yes yes 55 0 Corbel2 TrueType WinAnsi yes no yes 66 0 YMOFKW+Corbel CID TrueType Identity-H yes yes yes 61 0 Corbel3 CID TrueType Identity-H yes no yes 625 0 MinionPro-Bold3 Type 1C Custom yes no yes 53 0 MinionPro-It Type 1C WinAnsi yes no yes 54 0 BZKJVQ+MinionPro-Regular3 Type 1C Custom yes yes no 56 0 BZKJVQ+MTMI Type 1C Custom yes yes no 57 0 BZKJVQ+MTSYN2 Type 1C Custom yes yes no 58 0 BZKJVQ+MinionPro-Bold2 Type 1C Custom yes yes no 59 0 BZKJVQ+CMEX10 Type 1C Custom yes yes no 60 0 BZKJVQ+CMEX102 Type 1C Custom yes yes no 62 0 BZKJVQ+MinionPro-Regular2 Type 1C Custom yes yes no 63 0 BZKJVQ+MinionPro-Bold Type 1C Custom yes yes no 64 0 BZKJVQ+MTSYN Type 1C Custom yes yes no 65 0 BZKJVQ+MinionPro-Regular4 Type 1C Custom yes yes no 67 0 BZKJVQ+MTSYN6 Type 1C Custom yes yes no 68 0 BZKJVQ+MTSYN3 Type 1C Custom yes yes no 69 0 BZKJVQ+MTMI3 Type 1C Custom yes yes no 70 0 BZKJVQ+MTMI2 Type 1C Custom yes yes no 71 0 BZKJVQ+MinionPro-Regular7 Type 1C Custom yes yes no 72 0 BZKJVQ+MTGU Type 1C Custom yes yes no 73 0 BZKJVQ+MinionPro-Regular5 Type 1C Custom yes yes no 74 0 BZKJVQ+MTSYN4 Type 1C Custom yes yes no 75 0 BZKJVQ+MinionPro-Regular6 Type 1C Custom yes yes no 76 0 BZKJVQ+MTSYN5 Type 1C Custom yes yes no 77 0 BZKJVQ+MinionPro-Regular10 Type 1C Custom yes yes no 164 0 BZKJVQ+CMEX103 Type 1C Custom yes yes no 165 0 BZKJVQ+MTSYN7 Type 1C Custom yes yes no 166 0 BZKJVQ+MinionPro-Regular9 Type 1C Custom yes yes no 167 0 BZKJVQ+MTGU2 Type 1C Custom yes yes no 168 0 BZKJVQ+MTMI6 Type 1C Custom yes yes no 169 0 BZKJVQ+MinionPro-Regular11 Type 1C Custom yes yes no 170 0 BZKJVQ+MTSYN9 Type 1C Custom yes yes no 171 0 BZKJVQ+MTMI5 Type 1C Custom yes yes no 172 0 BZKJVQ+MTMI4 Type 1C Custom yes yes no 173 0 BZKJVQ+MTSYN8 Type 1C Custom yes yes no 174 0 BZKJVQ+MinionPro-Regular8 Type 1C Custom yes yes no 175 0 BZKJVQ+MTGU3 Type 1C Custom yes yes no 176 0 BZKJVQ+Calibri Type 1C WinAnsi yes yes no 252 0 BZKJVQ+Calibri2 Type 1C WinAnsi yes yes no 253 0 BZKJVQ+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 387 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-02-11 02:51:30 CET RepresentationInformation: pmc_10435455.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-02-08 03:11:32 CET Size: 1028931 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 669 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Distortion of Mendelian segregation across the Angus cattle genome uncovering regions affecting reproduction Children: Item: Title: Methods Children: Item: Title: Genotype data. Item: Title: Analytical models of transmission ratio distortion. Children: Item: Title: Allelic parameterization of TRD. Item: Title: Genotypic parameterization of TRD. Item: Title: Statistical analyses. Item: Title: Characterization of TRD effects on reproductive phenotypes. Item: Title: Ethics declarations. Item: Title: Results and discussion Children: Item: Title: Characterization of TRD on Angus genome. Item: Title: Relevant insight of TRD findings on Angus genome with deleterious alleles.. Children: Item: Title: Allelic patterns. Item: Title: Genotypic patterns. Item: Title: Model comparison. Item: Title: Validation and comparison of TRD phenomenon and lethality across breeds.. Item: Title: Validation of the identified TRD regions using reproductive phenotypes: heifer pregnancy trait. Item: Title: Conclusions Item: Title: References Item: Title: Acknowledgements Info: Title: Distortion of Mendelian segregation across the Angus cattle genome uncovering regions affecting reproduction Author: S. 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Id-Lahoucine J. Casellas D. Lu M. Sargolzaei S. Miller A. 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