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Destination: s3 Children: Item: Title: Clinical characteristics Destination: s3_1 Item: Title: Glycemic control optimization normalizes the main metabolic and lipidic variables at a 12-month follow-up Destination: s3_2 Item: Title: Newly diagnosed T2DM patients showed increased sLRP1 and decreased ANP plasma levels compared to controls Destination: s3_3 Item: Title: Metabolic optimization normalizes circulating levels of sLRP1 and ANP, and sLRP1/ANP ratio at a 12-month follow-up Destination: s3_4 Item: Title: Discussion Destination: s4 Children: Item: Title: Strengths and limitations Destination: s4_1 Item: Title: Conclusion Destination: s5 Item: Title: Data availability statement Destination: s6 Item: Title: Ethics statement Destination: s7 Item: Title: Author contributions Destination: s8 Item: Title: Funding Destination: bmark_1865464027 Item: Title: Acknowledgments Destination: bmark_-366698314 Item: Title: References Destination: bmark_2090415954 Info: Keywords: sLRP1, ANP, 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S, Sánchez-Quesada JL, Rives J, Garcia-Moll X, Vilades D, Perez A and Llorente-Cortes V (2023) Increased sLRP1 and decreased atrial natriuretic peptide plasma levels in newly diagnosed T2DM patients are normalized after optimization of glycemic control. Front. Endocrinol. 14:1236487 Copyright © 2023 García, Gil, Miñambres, Benitez-Amaro, Rodríguez, Claudi, Julve, Benitez, Sánchez-Quesada, Rives, Garcia-Moll, Vilades, Perez and Llorente-Cortes. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. sLRP1 ANP metabolic control T2DM hypoglycemic treatments Increased sLRP1 and decreased atrial natriuretic peptide plasma levels in newly diagnosed T2DM patients are normalized after optimization of glycemic control sLRP1, ANP, metabolic control, T2DM, hypoglycemic treatments True https://www.frontiersin.org/legal/copyright-statement Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 222, 686, 526, 707 Annotation: Subtype: Link Rect: 222, 661, 529, 682 Annotation: Subtype: Link Rect: 222, 636, 533, 657 Annotation: Subtype: Link Rect: 222, 611, 501, 632 Annotation: Subtype: Link Rect: 222, 586, 539, 607 Annotation: Subtype: Link Rect: 490, 496, 499, 505 Annotation: Subtype: Link Rect: 369, 481, 378, 490 Annotation: Subtype: Link Rect: 49, 33, 135, 40 Annotation: Subtype: Link Rect: 500, 33, 545, 40 Annotation: Subtype: Link Rect: 49, 691, 125, 706 Annotation: Subtype: Link Rect: 60, 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